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Drug eluting biliary stents to decrease stent failure rates:Areview of the literature 被引量:6
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作者 Joseph Shatzel Jisoo Kim +8 位作者 Kartik Sampath Sharjeel Syed Jennifer Saad Zilla H Hussain Kabir Mody J Marc Pipas Stuart Gordon timothy gardner Richard I Rothstein 《World Journal of Gastrointestinal Endoscopy》 CAS 2016年第2期77-85,共9页
Biliary stenting is clinically effective in relieving both malignant and non-malignant obstructions. However, there are high failure rates associated with tumor ingrowth and epithelial overgrowth as well as internally... Biliary stenting is clinically effective in relieving both malignant and non-malignant obstructions. However, there are high failure rates associated with tumor ingrowth and epithelial overgrowth as well as internally from biofilm development and subsequent clogging. Within the last decade, the use of prophylactic drug eluting stents as a means to reduce stent failure has been investigated. In this review we provide an overview of the current research on drug eluting biliary stents. While there is limited human trial data regarding the clinical benefit of drug eluting biliary stents in preventing stent obstruction, recent research suggests promise regarding their safety and potential efficacy. 展开更多
关键词 BILE ducts CHOLANGIOCARCINOMA ENDOSCOPY PANCREAS
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Studies of Microstructure of Kernels of Macadamia integrifolia and Its Hybrids through MRI, X-Ray Tomography and Confocal Microscopy
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作者 Warangkana Srichamnong Bill Price +4 位作者 timothy gardner Ryan Dean Ervan Plougonven Angelique Leonard George Srzednicki 《Journal of Food Science and Engineering》 2013年第9期503-516,共14页
The aim of this study was to apply the existing techniques that enable examination ofmacadamia kernels to provide a better understanding of physico-chemical properties of kernels during postharvest processing. These t... The aim of this study was to apply the existing techniques that enable examination ofmacadamia kernels to provide a better understanding of physico-chemical properties of kernels during postharvest processing. These techniques, such as X-ray tomography, could be applied for quality monitoring in the macadamia industry. The objectives of this study were to investigate the browning centre symptoms that usually occur in macadamia nuts-in-shell. The applied techniques included confocal microscopy, X-ray tomography and magnetic resonance imaging (MRI). Five different varieties of macadamia nuts (A38, 246, 816, 842 and Daddow) were selected to include distinct characteristics, such as drop pattern and growing location. Analysis of the microstructure of kernels by confocal microscopy showed the distribution of possible brown pigment compounds as well as the distribution of lipids, carbohydrates and proteins inside macadamia cells. Physical properties data, including shell density and seed to volume ratio, were obtained by X-ray tomography. Magnetic resonance diffusion tensor imaging used in this study showed marked differences in microstructure which indicate that different varieties exhibit different microstructures expressed as fraction ofanisotropy and apparent diffusion coefficient that appear to be related to the occurrence of the brown centre. Hence, the findings of this study have potential to improve the existing postharvest techniques used in the macadamia processing industry. They will be of benefit to the industry in terms of improved quality control and cost reduction. 展开更多
关键词 Macadamia integrifolia MICROSTRUCTURE magnetic resonance imaging confocal microscopy X-ray tomography
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