期刊文献+
共找到41篇文章
< 1 2 3 >
每页显示 20 50 100
Regulation role of miR-204 on SIRT1/VEGF in metabolic memory induced by high glucose in human retinal pigment epithelial cells
1
作者 Qiao-Ling Lai ting xie +1 位作者 Wei-Dong Zheng Yan Huang 《International Journal of Ophthalmology(English edition)》 SCIE CAS 2024年第7期1232-1237,共6页
AIM:To examine the regulatory role of microRNA-204(miR-204)on silent information regulator 1(SIRT1)and vascular endothelial growth factor(VEGF)under highglucose-induced metabolic memory in human retinal pigment epithe... AIM:To examine the regulatory role of microRNA-204(miR-204)on silent information regulator 1(SIRT1)and vascular endothelial growth factor(VEGF)under highglucose-induced metabolic memory in human retinal pigment epithelial(hRPE)cells.METHODS:Cells were cultured with either normal(5 mmol/L)or high D-glucose(25 mmol/L)concentrations for 8d to establish control and high-glucose groups,respectively.To induce metabolic memory,cells were cultured with 25 mmol/L D-glucose for 4d followed by culture with 5 mmol/L D-glucose for 4d.In addition,exposed in 25 mmol/L D-glucose for 4d and then transfected with 100 nmol/L miR-204 control,miR-204 inhibitor or miR-204 mimic in 5 mmol/L D-glucose for 4d.Quantitative reverse transcription-polymerase chain reaction(RT-qPCR)was used to detect miR-204 mRNA levels.SIRT1 and VEGF protein levels were assessed by immunohistochemical and Western blot.Flow cytometry was used to investigate apoptosis rate.RESULTS:It was found that high glucose promoted miR-204 and VEGF expression,and inhibited SIRT1 activity,even after the return to normal glucose culture conditions.Upregulation of miR-204 promoted apoptosis inhibiting SIRT1 and increasing VEGF expression.However,downregulation of miR-204 produced the opposite effects.CONCLUSION:The study identifies that miR-204 is the upstream target of SIRT1and VEGF,and that miR-204 can protect hRPE cells from the damage caused by metabolic memory through increasing SIRT1 and inhibiting VEGF expression. 展开更多
关键词 human retinal pigment epithelial metabolic memory microRNA-204 silent information regulator 1 vascular endothelial growth factor high-glucose
下载PDF
新药改善自体造血干细胞移植治疗复发或难治性霍奇金淋巴瘤患者的生存分析
2
作者 谢婷 刘慧敏 +5 位作者 山丹丹 刘薇 王轶 黄文阳 邱录贵 邹德慧 《中国肿瘤临床》 CAS CSCD 北大核心 2024年第2期76-80,共5页
目的:探讨新药时代自体造血干细胞移植(autologous hematopoietic stem cell transplantation,ASCT)治疗复发或难治性(relapse or refractory,R/R)经典型霍奇金淋巴瘤(classical Hodgkin's lymphoma,cHL)的疗效。方法:回顾性分析201... 目的:探讨新药时代自体造血干细胞移植(autologous hematopoietic stem cell transplantation,ASCT)治疗复发或难治性(relapse or refractory,R/R)经典型霍奇金淋巴瘤(classical Hodgkin's lymphoma,cHL)的疗效。方法:回顾性分析2010年1月至2022年12月在中国医学科学院血液病医院诊治的56例挽救治疗敏感、序贯ASCT治疗的R/R cHL患者,根据挽救治疗是否包含维布妥昔单抗(brentuximab vedotin,BV)或程序性死亡受体1(programmed death-1,PD-1)抑制剂分为新药组32例和非新药组24例,分析两组患者的临床特征及疗效,使用Kaplan-Meier法进行生存分析。结果:56例患者中男性35例,女性21例,中位移植年龄29(11~55)岁。中位随访时间56(2~137)个月,移植后预期5年总生存(overall survival,OS)率和无进展生存(progression-free survival,PFS)率分别为94.3%和75.8%。新药组患者的5年PFS更优(90.1%vs.59.1%,HR=0.23,95%CI:0.07~0.71,P=0.011),但OS差异无统计学意义(93.5%vs.95.5%,HR=1.2,95%CI:0.14~10.34,P=0.873)。结论:对于挽救治疗敏感的R/R cHL患者,ASCT仍然是标准的巩固治疗策略。新药在移植前、后的应用可进一步提高ASCT治疗R/R cHL患者的生存。 展开更多
关键词 霍奇金淋巴瘤 造血干细胞移植 维布妥昔单抗 PD-1抑制剂
下载PDF
Acute primary angle closure during the Omicron outbreak
3
作者 Dong Fang Wang-ting Li +9 位作者 Jia Liang Lu Chen Ning-Xin Dou Hui-Yan Zheng Can-Feng Huang ting xie Yi-Jing Zhuang Peng-Feng Li Xing-Xing Mao Shao-Chong Zhang 《International Journal of Ophthalmology(English edition)》 SCIE CAS 2024年第7期1337-1343,共7页
AIM:To investigate Omicron’s impact on clinical presentation of acute primary angle closure(APAC)in China.METHODS:A consecutive case series with historical controls was conducted at Shenzhen Eye Hospital,the largest ... AIM:To investigate Omicron’s impact on clinical presentation of acute primary angle closure(APAC)in China.METHODS:A consecutive case series with historical controls was conducted at Shenzhen Eye Hospital,the largest specialized hospital in Shenzhen,China.Medical records from a two-month period during the Omicron pandemic(December 1,2022,to January 31,2023)were compared with records from two control groups(12/2018–1/2019 and 12/2021–1/2022)before pandemic.Patients with APAC were included,and the prevalence of APAC and demographic characteristics in Omicron-infected and noninfected patients were compared.RESULTS:Seventy-one(23.43%)out of 303 patients were diagnosed with APAC in the pandemic cohort,which was 2.98 and 2.61 times higher than that in control cohorts(7.87%in 2019,8.96%in 2022,P<0.001).The pandemic cohort has significantly higher Omicron-infected rate(78.87%vs 0 vs 0;P<0.001),lower proportion of glaucoma history(16.90%vs 42.86%vs 41.67%,P=0.005),higher surgical rate(95.77%vs 83.33%vs 78.57%,P=0.024),higher total medical costs and larger pupil diameter(5.63±0.15 vs 4.68±0.15 vs 4.69±0.22 mm,P<0.01).In 83%Omicron-infected patients,ocular symptoms appeared within 3d after systemic symptoms onset.In multivariate analysis,Omicron infection(P<0.001)was the only independent predictor of pupil diameter.CONCLUSION:In the Omicron epidemic in China,there is an increase of prevalence and severity of APAC,particularly focusing on the first 3d following infection. 展开更多
关键词 Omicron acute primary angle closure ocular symptoms
下载PDF
The g-Good-Neighbor Connectivity of Some Cartesian Product Graphs 被引量:1
4
作者 Yinkui Li ting xie Xiaoxiao Qin 《Open Journal of Discrete Mathematics》 2023年第1期27-37,共11页
The g-good-neighbor connectivity of G is a generalization of the concept of connectivity, which is just for, and an important parameter in measuring the fault tolerance and reliability of interconnection network. Many... The g-good-neighbor connectivity of G is a generalization of the concept of connectivity, which is just for, and an important parameter in measuring the fault tolerance and reliability of interconnection network. Many well-known networks can be constructed by the Cartesian products of some simple graphs. In this paper, we determine the g-good-neighbor connectivity of some Cartesian product graphs. We give the exact value of g-good-neighbor connectivity of the Cartesian product of two complete graphs and for , mesh for , cylindrical grid and torus for . 展开更多
关键词 CONNECTIVITY The g-Good-Neighbor Connectivity Cartesian Product
下载PDF
Effect of miR-27b-3p and Nrf2 in human retinal pigment epithelial cell induced by high-glucose
5
作者 Qiao-Ling Lai ting xie +1 位作者 Wei-Dong Zheng Yan Huang 《International Journal of Ophthalmology(English edition)》 SCIE CAS 2023年第10期1582-1588,共7页
AIM:To determine whether the microRNA-27b-3p(miR-27b-3p)/NF-E2-related factor 2(Nrf2)pathway plays a role in human retinal pigment epithelial(hRPE)cell response to high glucose,how miR-27b-3p and Nrf2 expression are r... AIM:To determine whether the microRNA-27b-3p(miR-27b-3p)/NF-E2-related factor 2(Nrf2)pathway plays a role in human retinal pigment epithelial(hRPE)cell response to high glucose,how miR-27b-3p and Nrf2 expression are regulated,and whether this pathway could be specifically targeted.METHODS:hRPE cells were cultured in normal glucose or high glucose for 1,3,or 6d before measuring cellular proliferation rates using cell counting kit-8 and reactive oxygen species(ROS)levels using a dihydroethidium kit.miR-27b-3p,Nrf2,NAD(P)H quinone oxidoreductase 1(NQO1)and heme oxygenase-1(HO-1)mRNA and protein levels were analyzed using reverse transcription quantitative polymerase chain reaction(RT-qPCR)and immunocytofluorescence(ICF),respectively.Western blot analyses were performed to determine nuclear and total Nrf2 protein levels.Nrf2,NQO1,and HO-1 expression levels by RT-qPCR,ICF,or Western blot were further tested after miR-27b-3p overexpression or inhibitor lentiviral transfection.Finally,the expression level of those target genes was analyzed after treating hRPE cells with pyridoxamine.RESULTS:Persistent exposure to high glucose gradually suppressed hRPE Nrf2,NQO1,and HO-1 mRNA and protein levels and increased miR-27b-3p mRNA levels.High glucose also promoted ROS release and inhibited cellular proliferation.Nrf2,NQO1,and HO-1 mRNA levels decreased after miR-27b-3p overexpression and,conversely,both mRNA and protein levels increased after expressing a miR-27b-3p inhibitor.After treating hRPE cells exposed to high glucose with pyridoxamine,ROS levels tended to decreased,proliferation rate increased,Nrf2,NQO1,and HO-1 mRNA and protein levels were upregulated,and miR-27b-3p mRNA levels were suppressed.CONCLUSION:Nrf2 is a downstream target of miR-27b-3p.Furthermore,the miR-27b-3p inhibitor pyridoxamine can alleviate high glucose injury by regulating the miR-27b-3p/Nrf2 axis. 展开更多
关键词 human retinal pigment epithelial cell high glucose PYRIDOXAMINE microRNA-27b-3p NF-E2-related factor 2 NAD(P)H quinone oxidoreductase 1 heme oxygenase-1
下载PDF
Potassium transporter OsHAK9 regulates seed germination under salt stress by preventing gibberellin degradation through mediating OsGA2ox7 in rice
6
作者 Peng Zeng ting xie +10 位作者 Jiaxin Shen Taokai Liang Lu Yin Kexin Liu Ying He Mingming Chen Haijuan Tang Sunlu Chen Sergey Shabala Hongsheng Zhang Jinping Cheng 《Journal of Integrative Plant Biology》 SCIE CAS CSCD 2024年第4期731-748,共18页
Soil salinity has a major impact on rice seed germination,severely limiting rice production.Herein,a rice germination defective mutant under salt stress(gdss)was identified by using chemical mutagenesis.The GDSS gene ... Soil salinity has a major impact on rice seed germination,severely limiting rice production.Herein,a rice germination defective mutant under salt stress(gdss)was identified by using chemical mutagenesis.The GDSS gene was detected via MutMap and shown to encode potassium transporter OsHAK9.Phenotypic analysis of complementation and mutant lines demonstrated that OsHAK9 was an essential regulator responsible for seed germination under salt stress.OsHAK9 is highly expressed in germinating seed embryos.Ion contents and non-invasive micro-test technology results showed that OsHAK9 restricted K^(+)efflux in salt-exposed germinating seeds for the balance of K^(+)/Na^(+).Disruption of OsHAK9 significantly reduced gibberellin 4(GA4)levels,and the germination defective phenotype of oshak9a was partly rescued by exogenous GA_(3)treatment under salt stress.RNA sequencing(RNA-seq)and real-time quantitative polymerase chain reaction analysis demonstrated that the disruption of OsHAK9 improved the GA-deactivated gene OsGA2ox7 expression in germinating seeds under salt stress,and the expression of OsGA2ox7 was significantly inhibited by salt stress.Null mutants of OsGA2ox7 created using clustered,regularly interspaced,short palindromic repeat(CRISPR)/CRISPR-associated nuclease 9 approach displayed a dramatically increased seed germination ability under salt stress.Overall,our results highlight that OsHAK9 regulates seed germination performance under salt stress involving preventing GA degradation by mediating OsGA2ox7,which provides a novel clue about the relationship between GA and OsHAKs in rice. 展开更多
关键词 GDSS GIBBERELLINS potassium transporter RICE salt tolerance seed germination
原文传递
湖北地区孕妇碘营养状况及尿碘含量的影响因素分析 被引量:12
7
作者 易念华 谢婷 +5 位作者 刘念 孙雪静 吴兰 曾雪慧 唐念 盛青松 《中国现代医学杂志》 CAS 2020年第7期98-101,共4页
目的研究湖北地区孕妇碘营养状况及对孕妇尿碘含量的影响因素。方法采用整群分层抽样法进行抽样调查,抽取2015年10月-2017年10月湖北地区568例孕妇作为研究对象,收集研究对象的一般资料,观察孕妇碘营养状况。对比尿碘含量正常和尿碘含... 目的研究湖北地区孕妇碘营养状况及对孕妇尿碘含量的影响因素。方法采用整群分层抽样法进行抽样调查,抽取2015年10月-2017年10月湖北地区568例孕妇作为研究对象,收集研究对象的一般资料,观察孕妇碘营养状况。对比尿碘含量正常和尿碘含量异常对象的一般资料,对差异情况采用Logistic回归分析,分析孕妇尿碘含量的影响因素。结果研究对象中碘营养状况正常的孕妇258例,占45.42%;碘营养状况异常的孕妇310例,占54.58%。尿碘含量正常和尿碘含量异常的研究对象在文化程度、食盐量、海产品饮食频次、乳制品饮食频次、小米饮食频次、肉类饮食频次及碘剂补充情况方面比较,差异有统计学意义(P<0.05)。Logistic回归分析发现,文化程度、食盐量、海产品饮食频次、乳制品饮食频次、小米饮食频次、肉类饮食频次及碘剂补充情况是孕妇尿碘含量的影响因素(P<0.05)。结论湖北地区部分孕妇存在碘营养异常情况,应根据孕妇自身情况采取针对性干预,改善孕妇碘营养异常情况。 展开更多
关键词 孕妇 碘营养 尿碘 影响因素
下载PDF
The Drosophila ovary: an active stem cell community 被引量:8
8
作者 Daniel Kirilly ting xie 《Cell Research》 SCIE CAS CSCD 2007年第1期15-25,共11页
Only a small number of cells in adult tissues (the stem cells) possess the ability to self-renew at every cell division, while producing differentiating daughter cells to maintain tissue homeostasis for an organism... Only a small number of cells in adult tissues (the stem cells) possess the ability to self-renew at every cell division, while producing differentiating daughter cells to maintain tissue homeostasis for an organism's lifetime. The Drosophila ovary harbors three different types of stem cell populations (germline stem cell (GSC), somatic stem cell (SSC) and escort stem cell (ESC)) located in a simple anatomical structure known as germarium, rendering it one of the best model systems for studying stem cell biology due to reliable stem cell identification and available sophisticated genetic tools for manipulating gene functions. Particularly, the niche for the GSC is among the first and best studied ones, and studies on the GSC and its niche have made many unique contributions to a better understanding of relationships between stem cells and their niche. So far, both the GSC and the SSC have been shown to be regulated by extrinsic factors originating from their niche and intrinsic factors functioning within. Multiple signaling pathways are required for controlling GSC and SSC self-renewal and differentiation, which provide unique opportunities to investigate how multiple signals from the niche are interpreted in the stem cell. Since the Drosophila ovary contains three types of stem cells, it also provides outstanding opportunities to study how multiple stem cells in a given tissue work collaboratively to contribute to tissue function and maintenance. This review highlights recent major advances in studying Drosophila ovarian stem cells and also discusses future directions and challenges. 展开更多
关键词 Drosophila ovary germline stem cell somatic stem cell escort stem cell
下载PDF
A review and research on comprehensive characterization of microscopic shale gas reservoir space 被引量:5
9
作者 Yu-ru Yang Xiao-chen Liu +12 位作者 Hui Zhang Gang-yi Zhai Jiao-dong Zhang Zhi-fang Hu Shu-jing Bao Cong Zhang Xiang-hua Wang Xiao Yang Zheng-zhuang Liu ting xie Juan Chen Liyu Fang Li-juan Qin 《China Geology》 2019年第4期541-556,共16页
In this paper,substantial domestic and foreign research results of microscopic shale reservoir space were systemically reviewed,the research history consisting of simple observation and qualitative classification,quan... In this paper,substantial domestic and foreign research results of microscopic shale reservoir space were systemically reviewed,the research history consisting of simple observation and qualitative classification,quantitative research,the combination of qualitative and quantitative research successively as well as the characteristics of each research stage were summarized.In addition,the current problems existing in the characterization methods of shale reservoir space were also analyzed.Furthermore,based on massive actual detection of typical core samples obtained from more than 50 global shale gas wells and relevant practical experience,a comprehensive characterization method of combining qualitative with the semiquantitative characterization was put forward.In detail,the indicators of the qualitative characterization include pore combination type and organic-matter microscopic morphology type,while the core elements of the semi-quantitative characterization include the percentage of the organic-matter area and the plane porosity of the pores of different types.Based on the reference of the naming and classification of rocks,the three-end-member diagram method was used to characterize microscopic shale reservoir space.This is achieved by plotting the three end-member diagram of 3 kinds of first-order critical reservoir spaces,i.e.,organic-matter pores,matrix pores,and micro-fractures,in order to intuitively present the features of the microscopic pore combination.Meanwhile,statistic histograms of organic-matter microscopic morphology type and the plane porosity of different types of pores were adopted to characterize the development degree of second-order pores quantitatively.By this comprehensive characterization method,the importance of both pore combination and the microscopic morphology of organic matter were emphasized,revealing the control of organic-matter microscopic morphology over the organic-matter pores.What is more,high-resolution FE-SEM was adopted to obtain semi-quantitative statistics results.In this way,the features of pore development and pore combination were quantified,not only reflecting the types and storage capacity of the microscopic shale reservoir space,but also presenting the hydrocarbongenerating potential of organic matter in shale.Therefore,the results of this research are capable of providing in-depth microscopic information for the assessment and exploration and development of shale gas resources. 展开更多
关键词 SHALE SHALE gas Reservoir space RESEARCH status Types of PORE COMBINATIONS Oil-gas exploration engineering Longmaxi FORMATION Niutitang FORMATION Shahejie FORMATION Yanchang FORMATION China USA
下载PDF
Xiaoqinglong decoction reduces dendritic cell differentiation and regulates the Th1/Th2 balance in a mouse model of allergic asthma 被引量:2
10
作者 Juntang Yan Nan Deng +5 位作者 Qingguo Wang Xin Du Changxiang Li ting xie Yanxia Liu Min Liu 《Journal of Traditional Chinese Medical Sciences》 2020年第2期133-140,共8页
Background:Xiaoqinglong decoction(XQLD)is a classic Chinese medicinal formula that is widely used to treat allergic asthma.Recently,the use of XQLD to treat allergic asthma has inspired research to determine its mecha... Background:Xiaoqinglong decoction(XQLD)is a classic Chinese medicinal formula that is widely used to treat allergic asthma.Recently,the use of XQLD to treat allergic asthma has inspired research to determine its mechanism of action.Because dendritic cells(DCs)and the T helper 1(Th1)/Th2 cytokine balance play important roles in allergic asthma,the present work aimed to assess how these immune system components are affected by XQLD.Methods:Thirty-six female BALB/C mice were randomly divided into three groups:an ovalbumin-based allergic asthma model group,a XQLD treatment group,and a control group.Histology was performed with haematoxylin and eosin staining and immunohistochemical staining.Bronchoalveolar lavage fluid and blood were collected from the animals and used to analyze the composition of inflammatory cells and expression levels of the cytokines interleukin(IL)-5 and IL-13.The thymic stromal lymphopoietin(TSLP)protein expression was assessed by western blot analysis,and the Gata3 and Tbx21 mRNA levels were assessed by polymerase chain reaction.Results:Compared with the OVA group,the levels of TSLP expression,IL-5,IL-13,and immunoglobulin E in the XQLD group were lower(all P<.01).The level of IL-4-expressing cells(Th2 cells)was lower(P=.0013),and the percentage of IFN-g-expressing cells(Th1 cells)was higher in the XQLD group compared with those in the OVA group(P=.0065).In addition,XQLD increased the expression of Tbx21 mRNA and decreased the expression of Gata3 mRNA in the lungs compared with the OVA group(both P<.01).Conclusion:These findings suggest that XQLD may ameliorate the course of allergic asthma by regulating the Gata3/Tbx21 balance and inhibiting TSLP expression,changes which are indicative of an altered Th1/Th2 balance.Thus,the clinical effectiveness of XQLD in treating allergic asthma may be due to its regulation of Th1/Th2 balance. 展开更多
关键词 TH1/TH2 ALLERGIC DECOCTION
下载PDF
Morphology-Controlled Growth of A1N One-Dimensional Nanostructures 被引量:1
11
作者 ting xie Min YE +5 位作者 Xiaosheng FANG Zhi JIANG Li CHEN Mingguang KONG Yucheng WU Lide ZHANG 《Journal of Materials Science & Technology》 SCIE EI CAS CSCD 2008年第4期608-614,共7页
Aluminum nitride (AIN) nanowires, serrated nanoribbons, and nanoribbons were selectively obtained through a simple chloride assisted chemical vapor deposition process. The morphologies of the products could be contr... Aluminum nitride (AIN) nanowires, serrated nanoribbons, and nanoribbons were selectively obtained through a simple chloride assisted chemical vapor deposition process. The morphologies of the products could be controlled by adjusting the deposition position and the flux of the reactant gas. The morphologies and structures of the AIN products were investigated in detail. The formation mechanism of the as-prepared different morphologies of AIN one-dimensional (ID) nanostructures was discussed on the basis of the experimental results. 展开更多
关键词 Aluminum nitride Morphology-controlled growth One-dimensional nanostructure
下载PDF
Chloride Assisted Growth of Aluminum Nitride Nanobelts and Their Enhanced Dielectric Responses
12
作者 ting xie Min ye +4 位作者 Zhi Jiang Yong Qin Yu-cheng Wu Guo-wen Meng Li-de Zhang 《Chinese Journal of Chemical Physics》 SCIE CAS CSCD 北大核心 2008年第6期586-590,共5页
Aluminum nitride (AlN) nanobelts were successfully synthesized in high yield through a chloride assisted vapor-solid process. X-ray diffraction, transmission electron microscopy, and selected area electronic diffrac... Aluminum nitride (AlN) nanobelts were successfully synthesized in high yield through a chloride assisted vapor-solid process. X-ray diffraction, transmission electron microscopy, and selected area electronic diffraction demonstrate that the as-prepared nanobelts are pure, structurally uniform and single crystalline, and can be indexed to hexagonal wurtzite structure. The micro observations show that there exist no defects in the obtained nanobelts. The growth direction of the nanobelts is along [0001]. The frequency spectra of the relative dielectric constant and of the dielectric loss were measured in the frequency range of 50 Hz to 5 MHz. Analysis of these spectra indicates that the interface in samples has great influence on the dielectric behavior of samples. As compared with AlN micropowders, AlN nanobelts have much higher relative dielectric constant, especially at low frequencies at room temperature. 展开更多
关键词 Aluminum nitride NANOBELT Chloride assisted growth Dielectric property
下载PDF
Photodissociation Dynamics of CS_(2) Near 204 nm: The S(^(3)PJ)+CS(X^(1)∑^(+)) Channels
13
作者 Min Zhao Zhen-xing Li +8 位作者 ting xie Yao Chang Fu-yan Wu Qin Wang Wen-tao Chen Tao Wang Xing-an Wang Kai-jun Yuan Xue-ming Yang 《Chinese Journal of Chemical Physics》 SCIE CAS CSCD 2021年第1期95-101,I0012,共8页
We study the phot odissociation dynamics of CS2 in the ultraviolet region using the time-sliced velocity map ion imaging technique.The S(3 Pj)+CS(X1E+)product channels were observed and identified at four wavelengths ... We study the phot odissociation dynamics of CS2 in the ultraviolet region using the time-sliced velocity map ion imaging technique.The S(3 Pj)+CS(X1E+)product channels were observed and identified at four wavelengths of 201.36,203.10,204.85 and 206.61 nm.In the measured images of S(3Pj=2,1,0),the vibrational states of the CS(X1E+)co-products were partially resolved and the vibrational state distributions were determined.Moreover,the product total kinetic energy releases and the anisotropic parameters were derived.The relatively small anisotropic parameter values indicate that the S(3Pj=2丄0)+CS(X1E+)channels are very likely formed via the indirect predissociation process of CS2.The study of the S(3Pj=2,1;0)+CS(X1E+)channels,which come from the spin-orbit coupling dissociation process of CS2,shows that nonadiabatic process plays a role in the ultraviolet photodissociation of CS2. 展开更多
关键词 Carbon disulfide Time-sliced velocity map ion imaging PHOTODISSOCIATION
下载PDF
Wavelength Dependent Photodissociation of OCS via F 3^1ПRydberg State:CO(X1+)+S(1D2)Product Channel
14
作者 Fei Xu Yu-xin Tan +6 位作者 Dao-fu Yuan Wen-tao Chen Sheng-rui Yu ting xie Tao Wang Xue-ming Yang Xing-an Wang 《Chinese Journal of Chemical Physics》 SCIE CAS CSCD 2020年第6期691-696,I0002,共7页
The vacuum ultraviolet photodissociation of OCS via the F 3^1ΠRydberg states was investigated in the range of 134-140 nm by means of the time-sliced velocity map ion imaging technique.The images of S(^1D2)products fr... The vacuum ultraviolet photodissociation of OCS via the F 3^1ΠRydberg states was investigated in the range of 134-140 nm by means of the time-sliced velocity map ion imaging technique.The images of S(^1D2)products from the CO(X^1Σ^+)+S(^1D2)dissociation channel were acquired at five photolysis wavelengths,corresponding to a series of symmetric stretching vibrational excitations in OCS(F 3^1Π,v1=0-4).The total translational energy distributions,vibrational populations and angular distributions of CO(X^1Σ^+,v)coproducts were derived.The analysis of experimental results suggests that the excited OCS molecules dissociate to CO(X^1Σ^+)and S(^1D2)products via non-adiabatic couplings between the upper F 3^1Πstates and the lower-lying states both in the C∞v and Cs symmetry.Furthermore,strong wavelength dependent behavior has been observed:the greatly distinct vibrational populations and angular distributions of CO(X^1Σ^+,v)products from the lower(v1=0-2)and higher(v1=3,4)vibrational states of the excited OCS(F 3^1Π,v1)demonstrate that very different mechanisms are involved in the dissociation processes.This study provides evidence for the possible contribution of vibronic coupling and the crucial role of vibronic coupling on the vacuum ultraviolet photodissociation dynamics. 展开更多
关键词 Vacuum ultraviolet photodissociation Carbonyl sulfide Velocity map ion imaging
下载PDF
Mechanism of Radix isatidis in influencing pulmonary inflammation in tuberculosis rats by TLR4-NF-κB pathway
15
作者 Rui-hua Chen ting xie +1 位作者 Bing Tian Shan Song 《Journal of Hainan Medical University》 2019年第16期13-16,共4页
Objective:To investigate the mechanism of the effects of Radix isatidis on lung inflammation in tuberculosis rats through TLR4-NF-κB pathway.Methods:Forty-five SD rats were randomly divided into three groups(n=15 in ... Objective:To investigate the mechanism of the effects of Radix isatidis on lung inflammation in tuberculosis rats through TLR4-NF-κB pathway.Methods:Forty-five SD rats were randomly divided into three groups(n=15 in each group):control group,model group,and isatis root polysaccharide group.Through the tail vein injection of H37RV Mycobacterium tuberculosis model,the rats in the isatis root polysaccharide group received the intervention of Radix isatidis polysaccharides on the second day of infection.The serum inflammatory factors and the expression levels of TLR4-NF-κB pathway and inflammatory factors in lung tissue of each group were detected and compared.Results:A large number of Mycobacterium tuberculosis infection in the lung tissue of the model group,and clustered outside the cell.In the isatis root polysaccharide group,the CFU level was significantly lower compared with the model group,and the number of Mycobacterium tuberculosis was less than that of the model group(P<0.05),mainly distributed in tuberculous nodules and giant cells.The level of serum inflammatory factors in the model group was significantly higher than that in the control group(P<0.05).The levels of IL-1β,IL-6 and IFN-γin the serum of the isatis root polysaccharide group were significantly lower than those in the model group and significantly higher than those in the control group(P<0.05).The TLR4-NF-κB pathway and inflammatory factor mRNA levels in the lung tissue of the model group were significantly higher than those of the control group(P<0.05).The levels of TLR4,NF-κB,IL-1β,IL-6 and IFN-γin the lung tissue of the isatis root polysaccharide group were significantly lower than those of the model group and significantly higher than those of the control group(P<0.05).The expression level of TLR4-NF-κB pathway was significantly up-regulated in the lung tissue of model rats(P<0.05).The levels of TLR4 and NF-κB in the lung tissue of the isatis root polysaccharide group were significantly lower than those of the model group and significantly higher than those of the control group(P<0.05).Conclusion:Radix isatidis can alleviate lung inflammation caused by Mycobacterium tuberculosis infection by regulating TLR4-NF-κB pathway. 展开更多
关键词 MYCOBACTERIUM TUBERCULOSIS RADIX isatidis TOLL-LIKE RECEPTOR 4 Nuclear factorκB
下载PDF
Research on the Development Strategy of Community Education Based on Reverse Socialization
16
作者 ting xie Zongrong Liu 《教育研究前沿(中英文版)》 2022年第2期144-148,共5页
The exploration of China's community education development practice is well-aligned progressing,community education for improving the quality of the whole people and promoting social development is of great signif... The exploration of China's community education development practice is well-aligned progressing,community education for improving the quality of the whole people and promoting social development is of great significance.Reverse socialization plays an important role in alleviating intergenerational estrangement,providing new development direction and promoting balanced development of community education.To Promote the development of community education under the effect of reverse socialization,"the younger generations should influence the elder"so as to improve the cognition of community education;Optimize the policy,"new insights transforming the old concepts"so as to act well in community education publicity;At the mean time,the construction of characteristic community education work should be done as well. 展开更多
关键词 Reverse Socialization Community Education Development Strategy
下载PDF
Fe-doped Co_(3)O_(4) nanowire strutted 3D pinewood-derived carbon: A highly selective electrocatalyst for ammonia production via nitrate reduction 被引量:2
17
作者 Xuwei Liu Chaozhen Liu +12 位作者 Xun He Zhengwei Cai Kai Dong Jun Li Xiaoya Fan ting xie Xiya Yang Yonglan Luo Dongdong Zheng Shengjun Sun Sulaiman Alfaifi Feng Gong Xuping Sun 《Nano Research》 SCIE EI CSCD 2024年第4期2276-2282,共7页
Nitrate(NO_(3)^(-)),a nitrogen-containing pollutant,is prevalent in aqueous solutions,contributing to a range of environmental and health-related issues.The electrocatalytic reduction of NO_(3)^(-)holds promise as a s... Nitrate(NO_(3)^(-)),a nitrogen-containing pollutant,is prevalent in aqueous solutions,contributing to a range of environmental and health-related issues.The electrocatalytic reduction of NO_(3)^(-)holds promise as a sustainable approach to both eliminating NO_(3)^(-)and generating valuable ammonia(NH_(3)).Nevertheless,the reduction reaction of NO_(3)^(-)(NO_(3)^(-)RR),involving 8-electron transfer process,is intricate,necessitating highly efficient electrocatalysts to facilitate the conversion of NO_(3)^(-)to NH_(3).In this study,Fe-doped Co_(3)O_(4) nanowire strutted three-dimensional(3D)pinewood-derived carbon(Fe-Co_(3)O_(4)/PC)is proposed as a high-efficiency NO_(3)^(-)RR electrocatalyst for NH_(3) production.Operating within 0.1 M NaOH containing NO_(3)^(-),Fe-Co_(3)O_(4)/PC demonstrates exceptional performance,obtain an impressively large NH_(3) yield of 0.55 mmol·h^(-1)·cm^(-2) and an exceptionally high Faradaic efficiency of 96.5%at-0.5 V,superior to its Co_(3)O_(4)/PC counterpart(0.2 mmol·h^(-1)·cm^(-2),73.3%).Furthermore,the study delves into the reaction mechanism of Fe-Co_(3)O_(4) for NO_(3)^(-)RR through theoretical calculations. 展开更多
关键词 Fe-doped Co_(3)O_(4) nanowire pinewood-derived carbon electrocatalytic NO_(3)-reduction NH_(3) synthesis density functional theory
原文传递
Geochemistry and Zircon U-Pb and Hf Isotopes of Early Devonian Hardawu Granites in the Eastern Segment of the Ultrahigh-Pressure Metamorphic Belt, Northern Qaidam Basin
18
作者 Hua Li Ming Wang +8 位作者 Jiqing Li Haikui Tong Jiaxiang Dong Minggang Tian Xiaolin Chen Leguang Li ting xie Xiong Li Yuying Che 《Journal of Earth Science》 SCIE CAS CSCD 2024年第3期866-877,共12页
The Hardawu granites in the eastern segment of the ultrahigh-pressure metamorphic belt,the northern Qaidam Basin,were studied by whole-rock major and trace elements and in-situ zircon U-Pb geochronology and Hf isotope... The Hardawu granites in the eastern segment of the ultrahigh-pressure metamorphic belt,the northern Qaidam Basin,were studied by whole-rock major and trace elements and in-situ zircon U-Pb geochronology and Hf isotopes to discuss the petrogenesis and tectonic evolution.Geochronological results show that the granites have a crystallization age of 401±3 Ma,suggesting that they were formed in the Early Devonian.The granites have SiO2 contents of 75.32 wt.%-76.05 wt.%,total alkali contents of 8.23 wt.%-8.36 wt.%,and K2O/Na2O ratios of 1.62-1.91.They were rich in K2O,poor in TiO2,MnO,MgO,and P2O5,and have A/CNK values of 1.05-1.07,Rittmann indexδvalues of 2.05-2.14,and differentiation index(DI)values of 92.85-94.18.They are high potassium calc-alkaline,weakperaluminum,and highly differentiated I-type granites.The granites also show enrichment of large ion lithophile elements(LILE)such as Rb,Ba,and Th,and depletion of high field strength elements(HFSE)such as Nb,Ta,and Ti.The total REE concentrations range from 169 ppm to 232 ppm,with enrichments of light rare earth elements and negative Eu anomalies(δEu=0.39-0.55).The zirconεHf(t)values range from-0.65 to-2.29,and the two-stage model ages(tDM2)changed within a small range of 1.44 to 1.54 Ga,indicating that the magma of the Hardawu granites was originated from the partial melting of Mesoproterozoic lower crustal materials.Combined with previous studies,we suggest that the Hardawu granites were formed in the extensional tectonic setting after the collision between the Qaidam Block and the central and southern Qilian Block in the Early Devonian. 展开更多
关键词 GRANITE Early Devonian PETROGENESIS tectonic implication Qaidam Basin GEOCHEMISTRY
原文传递
Integration of urchin-like MnCo_(2)O_(4)@C core–shell nanowire arrays within porous copper current collector for superior performance Li-ion battery anodes
19
作者 Xue-Ru Zhang Qiong Wu +3 位作者 Yong Zhang Xi-Fei Li ting xie Yu-Cheng Wu 《Rare Metals》 SCIE EI CAS CSCD 2024年第2期599-611,共13页
Spinel MnCo_(2)O_(4) is a promising energy storage candidate as anode materials in lithium-ion batteries owing to synergistic effects of two intrinsic solid-state redox couples.However,low conductivity,poor rate capac... Spinel MnCo_(2)O_(4) is a promising energy storage candidate as anode materials in lithium-ion batteries owing to synergistic effects of two intrinsic solid-state redox couples.However,low conductivity,poor rate capacity and rapid capacity fading have seriously impaired its practical applications.To overcome the inferiorities,urchin-like MnCo_(2)O_(4)@C core–shell nanowire arrays have been fabricated directly within a porous copper current collector via a facile hydrothermal method followed by a chemical vapor deposition carbonization process.In a typical nanowire,the core is composed of interconnected MnCo_(2)O_(4)nanoparticles and the shell shows as a thin amorphous carbon layer.The integrated MnCo_(2)O_(4)@C/Cu structure could act as working anodes without using additives or polymer binders.While MnCo_(2)O_(4)@C/Cu possesses slightly longer Li-ion insertion/desertion pathway than that of MnCo_(2)O_(4)/Cu,the carbon shell could effectively prevent the pulverization of MnCo_(2)O_(4) and lower down charge transfer resistance and actively participate in Li-ion cycles.The rearrangement of carbon atoms during lithiation/delithiation cycling could inhibit the formation of passive solid electrolyte interphase films.As a result,the MnCo_(2)O_(4)@C/Cu electrode presents superior rate capacity(600 mAh·g^(−1) at 1 A·g^(−1)) and better stability(797 mAh·g^(−1) after 200 cycles at 100 mA·g^(−1)).The excellent reversible Li ion storage capacity,cycling stability and rate capacity endow MnCo_(2)O_(4)@C/Cu great potential as stable and high output integrated anode materials in Li-ion batteries. 展开更多
关键词 MnCo_(2)O_(4)@C Urchin-like nanowire arrays CORE-SHELL Integrated anode materials Lithium-ion batteries
原文传递
Artificial cavernosa-like tissue based on multibubble Matrigel and a human corpus cavernous fibroblast scaffold
20
作者 Yu-Zhuo Chen Yi-Hong Zhou +17 位作者 Min-Bo Yan Ming Xiao Biao Liu Ying-Hao Yin Xiao-Li Tan Yong-Quan Huang Yu-Hong Lin ting xie Jia-Li Tian Qi Wang Jian-Ying Li Zi-Zhou Meng Zheng Li Emily Xing Yu-Xin Tang Ya-Wei Li Zhong-Zhen Su Liang-Yu Zhao 《Asian Journal of Andrology》 SCIE CAS CSCD 2024年第3期260-267,共8页
Ex vivo tissue culture of the human corpus cavernosum(cc)can be used to explore the tissue structural changes and complex signaling networks.At present,artificial Cc-like tissues based on acellular or three-dimensiona... Ex vivo tissue culture of the human corpus cavernosum(cc)can be used to explore the tissue structural changes and complex signaling networks.At present,artificial Cc-like tissues based on acellular or three-dimensional(3D)-printed scaffolds are used to solve the scarcity of primary penis tissue samples.However,inconvenience and high costs limit the wide application of such methods.Here,we describe a simple,fast,and economical method of constructing artificial CC-like tissue.Human Cc fibroblasts(FBs),endothelial cells(ECs),and smooth muscle cells(SMCs)were expanded in vitro and mixed with Matrigel in specific proportions.A large number of bubbles were formed in the mixture by vortexing combined with pipette blowing,creating a porous,spongy,and spatial structure.The Cc FBs produced a variety of signaling factors,showed multidirectional differentiation potential,and grew in a 3D grid in Matrigel,which is necessary for CC-like tissue to maintain a porous structure as a cell scaffold.Within the C-like tissue,ECs covered the surface of the lumen,and SMCs were located inside the trabeculae,similar to the structure of the primary Cc.Various cell components remained stable for 3 days in vitro,but the EC content decreased on the 7th day.Wingless/integrated(WNT)signaling activation led to lumen atrophy and increased tissue fibrosis in CC-like tissue,inducing the same changes in characteristics as in the primary Cc.This study describes a preparation method for human artificial cC-like tissue that may provide an improved experimental platform for exploring the function and structure of the cC and conducting drug screening for erectile dysfunction therapy. 展开更多
关键词 artificial tissue corpus cavernosum ex vivo FIBROBLASTS
原文传递
上一页 1 2 3 下一页 到第
使用帮助 返回顶部