The aerosol number concentration and size distribution were measured with the newly developed Wide-range Particle Spectrometer in summer and winter of 2006 at the urban site of Jinan City. Here reported the characteri...The aerosol number concentration and size distribution were measured with the newly developed Wide-range Particle Spectrometer in summer and winter of 2006 at the urban site of Jinan City. Here reported the characteristics of fine particles of the different observation seasons. Relative high number concentrations for the particles in the diameter range of 10-500 nm were observed in both seasons. It was found that the dominant number distributed in particle diameter smaller than 100 nm and the percentage over the number concentration of all air particles is much higher than what has been measured in other urban sites over the world. The number mean diameter in summer was much smaller than in winter, strongly suggesting the different origin of ultrafine particles in different seasons. That is, particles in ultrafine mode mainly came from nucleation and new particle formation in summer while from traffic emission in winter. The diurnal variation also supported this point. Number concentration in the diameter range of 10-200 um got their peak values at noontime, well correlated with the mixing ratio of SO2 and the intensity of solar radiation in summer. While in winter, those in the same diameter range showed the main peaks during the traffic hours happened in the morning and evening.展开更多
青藏高原藏南谷地中部的玛不错湖位于印度夏季风和西风影响区内,对气候变化响应敏感。不同年份相同时相的遥感影像反映了湖面的变化特征,是探究区域气候变化的重要对象。湖岸堤和湖成阶地沉积物记录了湖面水位变化的历史,可帮助认识区...青藏高原藏南谷地中部的玛不错湖位于印度夏季风和西风影响区内,对气候变化响应敏感。不同年份相同时相的遥感影像反映了湖面的变化特征,是探究区域气候变化的重要对象。湖岸堤和湖成阶地沉积物记录了湖面水位变化的历史,可帮助认识区域古气候的变化和定量重建湖面波动。本文运用ArcGIS遥感解译、AMS ^( 14)C测年和DEM等方法确定玛不错北岸湖岸堤的高程和湖岸阶地的年代,结合湖成阶地剖面的沉积序列指示的湖面变化过程,重建晚更新世以来玛不错湖面的变化过程。S_(7)-S_(4)湖岸堤阶段,14256~13984 a BP之前,玛不错与其南侧的嘎拉错、多庆错为一体,是一个统一的大湖。S_(7)→S_(4),湖平面总体上呈逐渐下降的趋势,玛不错与多庆错、嘎拉错先后分离形成独立湖泊。S_(4)→S_(3)阶段,湖面逐渐上涨,分离的玛不错与嘎拉错重新连为一体,但这个过程持续时间比较短暂。S_(3)-S_(1)阶段,14256~13984 a BP之后,玛不错成为一个独立的湖泊。S_(3)→S_(1)阶段,湖面整体上呈逐渐下降的趋势。综合来看,晚更新世以来玛不错湖面经历了高→低→高→低的变化过程,湖面升降变化主要受区域大气降水和冰川融水的控制,反映了印度季风的强弱变化和全球气候的变化。近十年来遥感解译的湖面变化显示,玛不错2013-2015年期间呈萎缩状态,2016-2018年期间呈扩张状态,反映近年来青藏高原藏南谷地中部的气候有向暖湿化发展的趋势。该认识对于全球气候变暖背景下青藏高原气候环境变化趋势研究领域提供了新的参考。展开更多
目的探讨β胶原特殊序列(β-crosslaps,β-CTX)、总1型胶原氨基端延长肽(t-P1NP)及N端中段骨钙素(N-MID-OT)在绝经后女性骨质疏松性骨折风险评估中的应用价值。方法回顾性分析2020年2月至2022年12月解放军总医院第六医学中心收治的102...目的探讨β胶原特殊序列(β-crosslaps,β-CTX)、总1型胶原氨基端延长肽(t-P1NP)及N端中段骨钙素(N-MID-OT)在绝经后女性骨质疏松性骨折风险评估中的应用价值。方法回顾性分析2020年2月至2022年12月解放军总医院第六医学中心收治的102例绝经后骨质疏松(postmenopausal osteoporosis,PMOP)患者的临床资料,将其作为研究组,并根据是否发生骨折将其分为PMOP骨折组(39例)与PMOP未骨折组(63例),另选100名健康体检者作为对照组。记录所有研究对象的β-CTX、t-P1NP及N-MID-OT水平并进行比较,用ROC曲线评价β-CTX、t-P1NP及N-MID-OT在绝经后女性骨质疏松性骨折风险评估中的应用价值。结果研究组的平均体重、体质量指数、股骨颈骨密度(bone mineral density,BMD)、左髋总和BMD及L 1~4总和BMD均明显低于对照组(P<0.05);而两组研究对象的平均年龄、平均身高及绝经年龄等比较差异均无统计学意义(P>0.05)。研究组的β-CTX、t-P1NP及N-MID-OT均明显高于对照组(t值依次为12.688、37.430、26.599,P<0.05)。β-CTX+t-P1NP+N-MID-OT联合检测用于预测PMOP的AUC值为0.978,敏感度为98.04%,特异度为97.00%,表明β-CTX+t-P1NP+N-MID-OT三指标联合检测用于预测PMOP的效能更高。PMOP骨折组的β-CTX、t-P1NP及N-MID-OT均明显高于PMOP未骨折组(t值依次为6.078、16.363、12.227,P<0.05)。β-CTX+t-P1NP+N-MID-OT联合检测用于评估PMOP骨折风险的AUC值为0.939,敏感度为94.87%,特异度为95.24%,表明β-CTX+t-P1NP+N-MID-OT联合检测用于评估PMOP骨折风险的效能更高。结论PMOP患者β-CTX、t-P1NP及N-MID-OT水平均明显升高,而PMOP骨折患者β-CTX、t-P1NP及N-MID-OT水平升高更为明显,且β-CTX+t-P1NP+N-MID-OT联合检测可显著提高对PMOP预测及骨折风险评估效能,值得借鉴。展开更多
基金Project supported by the National Basic Research Project(973)of China(No.2005CB422203)the National Post-Doctor Foundation of China(No.20060390990).
文摘The aerosol number concentration and size distribution were measured with the newly developed Wide-range Particle Spectrometer in summer and winter of 2006 at the urban site of Jinan City. Here reported the characteristics of fine particles of the different observation seasons. Relative high number concentrations for the particles in the diameter range of 10-500 nm were observed in both seasons. It was found that the dominant number distributed in particle diameter smaller than 100 nm and the percentage over the number concentration of all air particles is much higher than what has been measured in other urban sites over the world. The number mean diameter in summer was much smaller than in winter, strongly suggesting the different origin of ultrafine particles in different seasons. That is, particles in ultrafine mode mainly came from nucleation and new particle formation in summer while from traffic emission in winter. The diurnal variation also supported this point. Number concentration in the diameter range of 10-200 um got their peak values at noontime, well correlated with the mixing ratio of SO2 and the intensity of solar radiation in summer. While in winter, those in the same diameter range showed the main peaks during the traffic hours happened in the morning and evening.
文摘青藏高原藏南谷地中部的玛不错湖位于印度夏季风和西风影响区内,对气候变化响应敏感。不同年份相同时相的遥感影像反映了湖面的变化特征,是探究区域气候变化的重要对象。湖岸堤和湖成阶地沉积物记录了湖面水位变化的历史,可帮助认识区域古气候的变化和定量重建湖面波动。本文运用ArcGIS遥感解译、AMS ^( 14)C测年和DEM等方法确定玛不错北岸湖岸堤的高程和湖岸阶地的年代,结合湖成阶地剖面的沉积序列指示的湖面变化过程,重建晚更新世以来玛不错湖面的变化过程。S_(7)-S_(4)湖岸堤阶段,14256~13984 a BP之前,玛不错与其南侧的嘎拉错、多庆错为一体,是一个统一的大湖。S_(7)→S_(4),湖平面总体上呈逐渐下降的趋势,玛不错与多庆错、嘎拉错先后分离形成独立湖泊。S_(4)→S_(3)阶段,湖面逐渐上涨,分离的玛不错与嘎拉错重新连为一体,但这个过程持续时间比较短暂。S_(3)-S_(1)阶段,14256~13984 a BP之后,玛不错成为一个独立的湖泊。S_(3)→S_(1)阶段,湖面整体上呈逐渐下降的趋势。综合来看,晚更新世以来玛不错湖面经历了高→低→高→低的变化过程,湖面升降变化主要受区域大气降水和冰川融水的控制,反映了印度季风的强弱变化和全球气候的变化。近十年来遥感解译的湖面变化显示,玛不错2013-2015年期间呈萎缩状态,2016-2018年期间呈扩张状态,反映近年来青藏高原藏南谷地中部的气候有向暖湿化发展的趋势。该认识对于全球气候变暖背景下青藏高原气候环境变化趋势研究领域提供了新的参考。
文摘目的探讨β胶原特殊序列(β-crosslaps,β-CTX)、总1型胶原氨基端延长肽(t-P1NP)及N端中段骨钙素(N-MID-OT)在绝经后女性骨质疏松性骨折风险评估中的应用价值。方法回顾性分析2020年2月至2022年12月解放军总医院第六医学中心收治的102例绝经后骨质疏松(postmenopausal osteoporosis,PMOP)患者的临床资料,将其作为研究组,并根据是否发生骨折将其分为PMOP骨折组(39例)与PMOP未骨折组(63例),另选100名健康体检者作为对照组。记录所有研究对象的β-CTX、t-P1NP及N-MID-OT水平并进行比较,用ROC曲线评价β-CTX、t-P1NP及N-MID-OT在绝经后女性骨质疏松性骨折风险评估中的应用价值。结果研究组的平均体重、体质量指数、股骨颈骨密度(bone mineral density,BMD)、左髋总和BMD及L 1~4总和BMD均明显低于对照组(P<0.05);而两组研究对象的平均年龄、平均身高及绝经年龄等比较差异均无统计学意义(P>0.05)。研究组的β-CTX、t-P1NP及N-MID-OT均明显高于对照组(t值依次为12.688、37.430、26.599,P<0.05)。β-CTX+t-P1NP+N-MID-OT联合检测用于预测PMOP的AUC值为0.978,敏感度为98.04%,特异度为97.00%,表明β-CTX+t-P1NP+N-MID-OT三指标联合检测用于预测PMOP的效能更高。PMOP骨折组的β-CTX、t-P1NP及N-MID-OT均明显高于PMOP未骨折组(t值依次为6.078、16.363、12.227,P<0.05)。β-CTX+t-P1NP+N-MID-OT联合检测用于评估PMOP骨折风险的AUC值为0.939,敏感度为94.87%,特异度为95.24%,表明β-CTX+t-P1NP+N-MID-OT联合检测用于评估PMOP骨折风险的效能更高。结论PMOP患者β-CTX、t-P1NP及N-MID-OT水平均明显升高,而PMOP骨折患者β-CTX、t-P1NP及N-MID-OT水平升高更为明显,且β-CTX+t-P1NP+N-MID-OT联合检测可显著提高对PMOP预测及骨折风险评估效能,值得借鉴。
