Fengyun meteorological satellites have undergone a series of significant developments over the past 50 years.Two generations,four types,and 21 Fengyun satellites have been developed and launched,with 9 currently opera...Fengyun meteorological satellites have undergone a series of significant developments over the past 50 years.Two generations,four types,and 21 Fengyun satellites have been developed and launched,with 9 currently operational in orbit.The data obtained from Fengyun satellites is employed in a multitude of applications,including weather forecasting,meteorological disaster prevention and reduction,climate change,global environmental monitoring,and space weather.These data products and services are made available to the global community,resulting in tangible social and economic benefits.In 2023,two Fengyun meteorological satellites were successfully launched.This report presents an overview of the two recently launched Fengyun satellites and currently in orbit Fengyun satellites,including an evaluation of their remote sensing instruments since 2022.Additionally,it addresses the subject of Fengyun satellite data archiving,data services,application services,international cooperation,and supporting activities.Furthermore,the development prospects have been outlined.展开更多
目的:探讨LncRNA PRNCR1(prostate cancer non-coding RNA 1)相关的4个基因多态性位点与胃癌发病风险及病理特征的相关性。方法:研究纳入300例经病理确诊的胃癌患者和300例健康者进行病例对照研究;基因分型采用Mass-array基因分析平台完...目的:探讨LncRNA PRNCR1(prostate cancer non-coding RNA 1)相关的4个基因多态性位点与胃癌发病风险及病理特征的相关性。方法:研究纳入300例经病理确诊的胃癌患者和300例健康者进行病例对照研究;基因分型采用Mass-array基因分析平台完成;采用酶联免疫吸附实验(ELISA)检测幽门螺杆菌(H. pylori)感染状态。结果:LncRNA PRNCR1 rs16901946位点的基因型分布在对照组及病例组中有显著性差异(P=0.018)。与野生型AA基因型相比,rs16901946位点AG基因型(AG vs. AA:校正后OR=1.41,95%CI:1.00～1.98,P=0.048)、GG基因型(GG vs. AA:校正后OR=2.57,95%CI:1.15～5.75,P=0.022)及AG/GG基因型(AG/GG vs. AA:校正后OR=1.51,95%CI:1.09～2.09,P=0.014)的胃癌相对发病风险较高。亚组分析显示,该位点在男性(AG/GG vs. AA:校正后OR=1.82,95%CI:1.23～2.69,P=0.003)、在H. pylori感染人群(AG/GG vs. AA:校正后OR=1.83,95%CI:1.16～2.89,P=0.009)发病风险相对较高。对肿瘤病理特征进行亚组分析显示,该位点与贲门癌的发病风险相关(AG/GG vs. AA:校正后OR=1.58,95%CI:1.10～2.28,P=0.011)、早期胃癌风险相关(AG/GG vs. AA:校正后OR=1.88,95%CI:1.18～2.98,P=0.008)。结论:lncRNA PRNCR1 rs16901946的遗传多态性位点与胃癌发病风险相关,在男性及H. pylori感染阳性人群中的相对风险高。展开更多
基金Supported by National Natural Science Foundation of China(42274217)。
文摘Fengyun meteorological satellites have undergone a series of significant developments over the past 50 years.Two generations,four types,and 21 Fengyun satellites have been developed and launched,with 9 currently operational in orbit.The data obtained from Fengyun satellites is employed in a multitude of applications,including weather forecasting,meteorological disaster prevention and reduction,climate change,global environmental monitoring,and space weather.These data products and services are made available to the global community,resulting in tangible social and economic benefits.In 2023,two Fengyun meteorological satellites were successfully launched.This report presents an overview of the two recently launched Fengyun satellites and currently in orbit Fengyun satellites,including an evaluation of their remote sensing instruments since 2022.Additionally,it addresses the subject of Fengyun satellite data archiving,data services,application services,international cooperation,and supporting activities.Furthermore,the development prospects have been outlined.
文摘目的:探讨LncRNA PRNCR1(prostate cancer non-coding RNA 1)相关的4个基因多态性位点与胃癌发病风险及病理特征的相关性。方法:研究纳入300例经病理确诊的胃癌患者和300例健康者进行病例对照研究;基因分型采用Mass-array基因分析平台完成;采用酶联免疫吸附实验(ELISA)检测幽门螺杆菌(H. pylori)感染状态。结果:LncRNA PRNCR1 rs16901946位点的基因型分布在对照组及病例组中有显著性差异(P=0.018)。与野生型AA基因型相比,rs16901946位点AG基因型(AG vs. AA:校正后OR=1.41,95%CI:1.00～1.98,P=0.048)、GG基因型(GG vs. AA:校正后OR=2.57,95%CI:1.15～5.75,P=0.022)及AG/GG基因型(AG/GG vs. AA:校正后OR=1.51,95%CI:1.09～2.09,P=0.014)的胃癌相对发病风险较高。亚组分析显示,该位点在男性(AG/GG vs. AA:校正后OR=1.82,95%CI:1.23～2.69,P=0.003)、在H. pylori感染人群(AG/GG vs. AA:校正后OR=1.83,95%CI:1.16～2.89,P=0.009)发病风险相对较高。对肿瘤病理特征进行亚组分析显示,该位点与贲门癌的发病风险相关(AG/GG vs. AA:校正后OR=1.58,95%CI:1.10～2.28,P=0.011)、早期胃癌风险相关(AG/GG vs. AA:校正后OR=1.88,95%CI:1.18～2.98,P=0.008)。结论:lncRNA PRNCR1 rs16901946的遗传多态性位点与胃癌发病风险相关,在男性及H. pylori感染阳性人群中的相对风险高。
