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Fabrication of lightweight 3D interpenetrated NiTi@Mg composite with superior bending properties
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作者 Yu-jing liU Xiao-chun liU +4 位作者 Kun-mao li Xiang WU Sheng-feng ZHOU wei li Wen-cai ZHANG 《Transactions of Nonferrous Metals Society of China》 SCIE EI CAS CSCD 2024年第11期3569-3584,共16页
A NiTi@Mg interpenetrating phase composite with high strength and lightweight was prepared by additive manufacturing(AM)and infiltration technology,and the interface bonding,three-point bending properties and cyclic c... A NiTi@Mg interpenetrating phase composite with high strength and lightweight was prepared by additive manufacturing(AM)and infiltration technology,and the interface bonding,three-point bending properties and cyclic compressive properties of NiTi@Mg composites were investigated.The results show that the metallurgically bonded interface is formed at the NiTi/Mg interfaces.The bending strength and compressive strength of the NiTi@Mg composite are 2.5 and 1.7 times higher than those of the NiTi scaffold,respectively.During the bending deformation process,a large number of dislocations are observed to accumulate in the soft Mg area at the interface.Furthermore,the finite element model showed that the stress accumulation area,where the bending crack is initiated,is located at the interface of NiTi and Mg.The strengthening mechanism of NiTi@Mg composites is attributed to the twinning strengthening of Mg and heterogeneous structure strengthening. 展开更多
关键词 metal composites NiTi@Mg bending properties finite element simulation strengthening mechanism
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Susceptibility weighted imaging in the evaluation of hemorrhagic diffuse axonal injury 被引量:6
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作者 Jing-jing Tao wei-jiang Zhang +5 位作者 Dong Wang Chun-juan Jiang Hua Wang wei li wei-yang Ji Qing Wang 《Neural Regeneration Research》 SCIE CAS CSCD 2015年第11期1879-1881,共3页
Diffuse axonal injury(DAI)is axonal and small vessel injury produced by a sudden acceleration of the head by an external force,and is a major cause of death and severe disability(Paterakis et al.,2000).Prognosis i... Diffuse axonal injury(DAI)is axonal and small vessel injury produced by a sudden acceleration of the head by an external force,and is a major cause of death and severe disability(Paterakis et al.,2000).Prognosis is poorer in patients with apparent hemorrhage than in those without(Paterakis et al.,2000).Therefore,it is important to identify the presence and precise position of hemorrhagic foci for a more accurate diagnosis.CT and magnetic resonance imaging(MRI)have long been applied in the diagnosis of DAI, but they are not sensitive enough for the detection of small hemorrhagic foci, and cannot meet the requirements for early diagnosis. A major advance in MRI has been the development of susceptibility weighted imaging (SWI), which has greatly increased the ability to detect small hemorrhagic foci after DAI (Ashwal et al., 2006). 展开更多
关键词 Susceptibility weighted imaging in the evaluation of hemorrhagic diffuse axonal injury SWI GCS FLAIR DWI
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Mitochondrial dysfunction and quality control lie at the heart of subarachnoid hemorrhage 被引量:5
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作者 Jiatong Zhang Qi Zhu +4 位作者 Jie Wang Zheng Peng Zong Zhuang Chunhua Hang wei li 《Neural Regeneration Research》 SCIE CAS CSCD 2024年第4期825-832,共8页
The dramatic increase in intracranial pressure after subarachnoid hemorrhage leads to a decrease in cerebral perfusion pressure and a reduction in cerebral blood flow.Mitochondria are directly affected by direct facto... The dramatic increase in intracranial pressure after subarachnoid hemorrhage leads to a decrease in cerebral perfusion pressure and a reduction in cerebral blood flow.Mitochondria are directly affected by direct factors such as ischemia,hypoxia,excitotoxicity,and toxicity of free hemoglobin and its degradation products,which trigger mitochondrial dysfunction.Dysfunctional mitochondria release large amounts of reactive oxygen species,inflammatory mediators,and apoptotic proteins that activate apoptotic pathways,further damaging cells.In response to this array of damage,cells have adopted multiple mitochondrial quality control mechanisms through evolution,including mitochondrial protein quality control,mitochondrial dynamics,mitophagy,mitochondrial biogenesis,and intercellular mitochondrial transfer,to maintain mitochondrial homeostasis under pathological conditions.Specific interventions targeting mitochondrial quality control mechanisms have emerged as promising therapeutic strategies for subarachnoid hemorrhage.This review provides an overview of recent research advances in mitochondrial pathophysiological processes after subarachnoid hemorrhage,particularly mitochondrial quality control mechanisms.It also presents potential therapeutic strategies to target mitochondrial quality control in subarachnoid hemorrhage. 展开更多
关键词 mitochondrial biogenesis mitochondrial dynamics mitochondrial dysfunction mitochondrial fission and fusion mitochondrial quality control MITOPHAGY subarachnoid hemorrhage
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Alkyl dimethyl betaine activates the low-temperature collection capacity of sodium oleate for scheelite 被引量:2
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作者 Xu Wang Zhengquan Zhang +5 位作者 Yanfang Cui wei li Congren Yang Hao Song Wenqing Qin Fen Jiao 《International Journal of Minerals,Metallurgy and Materials》 SCIE EI CSCD 2024年第1期71-80,共10页
The impact of alkyl dimethyl betaine (ADB) on the collection capacity of sodium oleate (NaOl) at low temperatures was evaluated using flotation tests at various scales. The low-temperature synergistic mechanism of ADB... The impact of alkyl dimethyl betaine (ADB) on the collection capacity of sodium oleate (NaOl) at low temperatures was evaluated using flotation tests at various scales. The low-temperature synergistic mechanism of ADB and NaOl was explored by infrared spectroscopy, X-ray photoelectron spectroscopy, surface tension measurement, foam performance test, and flotation reagent size measurement.The flotation tests revealed that the collector mixed with octadecyl dimethyl betaine (ODB) and NaOl in a mass ratio of 4:96 exhibited the highest collection capacity. The combined collector could increase the scheelite recovery by 3.48% at low temperatures of 8–12℃. This is particularly relevant in the Luanchuan area, which has the largest scheelite concentrate output in China. The results confirmed that ODB enhanced the collection capability of NaOl by improving the dispersion and foaming performance. Betaine can be introduced as an additive to NaOl to improve the recovery of scheelite at low temperatures. 展开更多
关键词 SCHEELITE BETAINE low temperature synergistic effect dispersion FOAMABILITY
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Fine mapping and characterization of stripe rust resistance gene YrAYH in near-isogenic lines derived from a cross involving wheat landrace Anyuehong 被引量:1
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作者 li Long Jue li +19 位作者 linyu Huang Huiling Jin Fangnian Guan Haipeng Zhang Sasa Zhao Hao li Zhien Pu wei li Qiantao Jiang Yuming wei Jian Ma Houyang Kang Shoufen Dai Pengfei Qi Qiang Xu Mei Deng Youliang Zheng Yunfeng Jiang Matthew James Moscou Guoyue Chen 《The Crop Journal》 SCIE CSCD 2024年第3期826-835,共10页
Stripe rust,caused by Puccinia striiformis f.sp.tritici(Pst),is a devastating disease in wheat worldwide.Discovering and characterizing new resistance genes/QTL is crucial for wheat breeding programs.In this study,we ... Stripe rust,caused by Puccinia striiformis f.sp.tritici(Pst),is a devastating disease in wheat worldwide.Discovering and characterizing new resistance genes/QTL is crucial for wheat breeding programs.In this study,we fine-mapped and characterized a stripe rust resistance gene,YRAYH,on chromosome arm 5BL in the Chinese wheat landrace Anyuehong(AYH).Evaluations of stripe rust response to prevalent Chinese Pst races in near-isogenic lines derived from a cross of Anyuehong and Taichung 29 showed that YrAYH conferred a high level of resistance at all growth stages.Fine mapping using a large segregating population of 9748 plants,narrowed the YRAYH locus to a 3.7 Mb interval on chromosome arm 5BL that included 61 annotated genes.Transcriptome analysis of two NIL pairs identified 64 upregulated differentially expressed genes(DEGs)in the resistant NILs(NILs-R).Annotations indicated that many of these genes have roles in plant disease resistance pathways.Through a combined approach of fine-mapping and transcriptome sequencing,we identified a serine/threonine-protein kinase SRPK as a candidate gene underlying YrAYH.A unique 25 bp insertion was identified in the NILs-R compared to the NILs-S and previously published wheat genomes.An InDel marker was developed and co-segregated with YrAYH.Agronomic trait evaluation of the NILs suggested that YrAYH not only reduces the impact of stripe rust but was also associated with a gene that increases plant height and spike length. 展开更多
关键词 Candidate gene analysis Crop protection Puccinia striiformis Transcriptome analyses
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Ontology modeling of semantics in social media:Public issue knowledge base (PIKB)of the Weibo 被引量:2
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作者 Yan ZHOU wei li +1 位作者 Xingfu YUAN Pengyi ZHANG 《Chinese Journal of Library and Information Science》 2014年第1期16-30,共15页
Purpose:This study aims to construct an ontology to model the semantics of social media streams,in particular,trending topics and public issues.Design/methodology/approach:Our knowledge base included 10 public events ... Purpose:This study aims to construct an ontology to model the semantics of social media streams,in particular,trending topics and public issues.Design/methodology/approach:Our knowledge base included 10 public events and topics from Weibo respectively,which were collected through keyword search and a crawler program.We used a semi-automatic approach to model and annotate the semantics in social media,and adapted the multi-layered ontology to refine the design based on previous researches,then we used named entity recognition(NER) to extract entities to instantiate the ontology.Relationships were extracted based on co-occurrence measures.Finally,we manually conducted post-filtering evaluation and edited the extracted entities and relationships.Findings:An initial assessment demonstrated that our multi-layered ontology supports various types of queries and analyses in the public issue knowledge base(PIKB),which can serve as an effective tool to query,understand and trace public issues.Research limitations:Manual involvement cannot meet the requirements for challenges of sustainable developments.Since the relationships extracted are fully based on the co-occurrence of entities,rich semantic relationships,such as how much the key players have been involved,could not be fully reflected.Besides,the user evaluation is necessary for further ontology assessment.Practical implications:The PIKB can be used by regular Web users and policy makers to query,understand,and make sense of public events and topics.The methodology and reusable ontology model are useful for institutions that are interested in making use of the social media data.Originality/value:In this study,a multi-layered ontology is applied to model the evolving semantics of public events and trending topics in social media,and the semi-automatic approach could make it possible to extract entities and relationships from large amount of unstructured short texts of user generated content(UGC) from social media. 展开更多
关键词 ONTOLOGY Knowledge organization Public issue knowledge base(PIKB) Public issues Social media
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Clinical analysis of colistin sulfate in the treatment of pneumonia caused by carbapenem-resistant Gram-negative bacteria 被引量:1
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作者 Hai-Chang Xu Yan Cui +6 位作者 Xue-Ying Wang Hai-Bo Wu wei li Dan Wang Na lin lin lin Ying-Hui Zhang 《World Journal of Clinical Cases》 SCIE 2024年第13期2173-2181,共9页
BACKGROUND Multidrug-resistant Gram-negative bacteria,exacerbated by excessive use of antimicrobials and immunosuppressants,are a major health threat.AIM To study the clinical efficacy and safety of colistin sulfate i... BACKGROUND Multidrug-resistant Gram-negative bacteria,exacerbated by excessive use of antimicrobials and immunosuppressants,are a major health threat.AIM To study the clinical efficacy and safety of colistin sulfate in the treatment of carbapenem-resistant Gram-negative bacilli-induced pneumonia,and to provide theoretical reference for clinical diagnosis and treatment.METHODS This retrospective analysis involved 54 patients with Gram-negative bacilli pneumonia admitted to intensive care unit of The General Hospital of the Northern Theater Command of the People's Liberation Army of China from August 2020 to June 2022.After bacteriological culture,the patients'airway secretions were collected to confirm the presence of Gram-negative bacilli.The patients were divided into the experimental and control groups according to the medication used.The research group consisted of 28 patients who received polymyxin sulfate combined with other drugs through intravenous,nebulization,or intravenous combined with nebulization,with a daily dosage of 1.5–3.0 million units.The control group consisted of 26 patients who received standard dosages of other antibiotics(including sulbactam sodium for injection,cefoperazone sodium sulbactam for injection,tigecycline,meropenem,or vaborbactam).RESULTS Of the 28 patients included in the research group,26 patients showed improvement,treatment was ineffective for two patients,and one patient died,with the treatment efficacy rate of 92.82%.Of the 26 patients in the control group,18 patients improved,treatment was ineffective for eight patients,and two patients died,with the treatment efficacy rate of 54.9%;significant difference was observed between the two groups(P<0.05).The levels of white blood cell(WBC),procalcitonin(PCT),and C-reactive protein(CRP)in both groups were significantly lower after treatment than before treatment(P<0.05),and the levels of WBC,PCT,and CRP in the research group were significantly lower than those in the control group(P<0.05).Compared with before treatment,there were no significant changes in aspartate aminotransferase,creatinine,and glomerular filtration rate in both groups,while total bilirubin and alanine aminotransferase decreased after treatment(P<0.05)with no difference between the groups.In patients with good clinical outcomes,the sequential organ failure assessment(SOFA)score was low when treated with inhaled polymyxin sulfate,and specific antibiotic treatment did not improve the outcome.Sepsis and septic shock as well as a low SOFA score were independent factors associated with good clinical outcomes.CONCLUSION Polymyxin sulfate has a significant effect on the treatment of patients with multiple drug-resistant Gram-negative bacilli pneumonia and other infections in the lungs and is safe and reliable.Moreover,the administration route of low-dose intravenous injection combined with nebulization shows better therapeutic effects and lower adverse reactions,providing new ideas for clinical administration. 展开更多
关键词 Colistin sulfate Extensively drug-resistant PNEUMONIA Intravenous combined with nebulization Sepsis NEPHROTOXICITY NEUROTOXICITY
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How do lateral septum projections to the ventral CA1 influence sociability?
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作者 Dan Wang Di Zhao +12 位作者 Wentao Wang Fengai Hu Minghu Cui Jing liu Fantao Meng Cuilan liu Changyun Qiu Dunjiang liu Zhicheng Xu Yameng Wang Yu Zhang wei li Chen li 《Neural Regeneration Research》 SCIE CAS CSCD 2024年第8期1789-1801,共13页
Social dysfunction is a risk factor for several neuropsychiatric illnesses.Previous studies have shown that the lateral septum(LS)-related pathway plays a critical role in mediating social behaviors.Howeve r,the role ... Social dysfunction is a risk factor for several neuropsychiatric illnesses.Previous studies have shown that the lateral septum(LS)-related pathway plays a critical role in mediating social behaviors.Howeve r,the role of the connections between the LS and its downstream brain regions in social behavio rs remains unclea r.In this study,we conducted a three-chamber test using electrophysiological and chemogenetic approaches in mice to determine how LS projections to ventral CA1(vCA1)influence sociability.Our res ults showed that gamma-aminobutyric acid(GABA)-e rgic neuro ns were activated following social experience,and that social behavio rs were enhanced by chemogenetic modulation of these neurons.Moreover,LS GABAergic neurons extended their functional neural connections via vCA1 glutamatergic pyramidal neurons,and regulating LSGABA→vCA1Gluneural projections affected social behaviors,which were impeded by suppressing LSprojecting vCA1 neuronal activity or inhibiting GABAAreceptors in vCA1.These findings support the hypothesis that LS inputs to the vCA1 can control social prefe rences and social novelty behaviors.These findings provide new insights rega rding the neural circuits that regulate sociability. 展开更多
关键词 chemogenetics GABA receptor GABAergic neurons glutamatergic neurons lateral septum neural excitability neural projection social novelty social preference ventral CA1
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A Single-Board Integrated Millimeter-Wave Asymmetric Full-Digital Beamforming Array for B5G/6G Applications
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作者 Qingqing lin Jun Xu +9 位作者 Kai Chen Long Wang wei li Zhiqiang Yu Guangqi Yang Jianyi Zhou Zhe Chen Jixin Chen Xiaowei Zhu wei Hong 《Engineering》 SCIE EI CAS CSCD 2024年第10期35-50,共16页
In this article,a single-board integrated millimeter-wave(mm-Wave)asymmetric full-digital beamforming(AFDBF)array is developed for beyond-fifth-generation(B5G)and sixth-generation(6G)communications.The proposed integr... In this article,a single-board integrated millimeter-wave(mm-Wave)asymmetric full-digital beamforming(AFDBF)array is developed for beyond-fifth-generation(B5G)and sixth-generation(6G)communications.The proposed integrated array effectively addresses the challenge of arranging a large number of ports in a full-digital array by designing vertical connections in a three-dimensional space and successfully integrating full-digital transmitting(Tx)and receiving(Rx)arrays independently in a single board.Unlike the traditional symmetric array,the proposed asymmetric array is composed of an 8×8 Tx array arranged in a square shape and an 8+8 Rx array arranged in an L shape.The center-to-center distance between two adjacent elements is 0.54k0 for both the Tx and Rx arrays,where k0 is the free-space wavelength at 27 GHz.The proposed AFDBF array possesses a more compact structure and lower system hardware cost and power consumption compared with conventional brick-type full-digital arrays.In addition,the energy efficiency of the proposed AFDBF array outperforms that of a hybrid beamforming array.The measurement results indicate that the operating frequency band of the proposed array is 24.25–29.50 GHz.An eight-element linear array within the Tx array can achieve a scanning angle ranging from-47°to+47°in both the azimuth and the elevation planes,and the measured scanning range of each eight-element Rx array is–45°to+45°.The measured maximum effective isotropic radiated power(EIRP)of the eight-element Tx array is 43.2 dBm at 28.0 GHz(considering the saturation point).Furthermore,the measured error vector magnitude(EVM)is less than 3%when 64-quadrature amplitude modulation(QAM)waveforms are used. 展开更多
关键词 Full-digital beamforming array Asymmetric structure Single-board integrated Beyond fifth-generation and sixthgeneration Millimeter-wave communication Complex modulation Printed circuit board Vertical connection
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Fixed-Time Antidisturbance Consensus Tracking for Nonlinear Multiagent Systems With Matching and Mismatching Disturbances
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作者 Xiangmin Tan Chunyan Hu +3 位作者 Guanzhen Cao Qinglai wei wei li Bo Han 《IEEE/CAA Journal of Automatica Sinica》 SCIE EI CSCD 2024年第6期1410-1423,共14页
In this paper,fixed-time consensus tracking for mul-tiagent systems(MASs)with dynamics in the form of strict feed-back affine nonlinearity is addressed.A fixed-time antidistur-bance consensus tracking protocol is prop... In this paper,fixed-time consensus tracking for mul-tiagent systems(MASs)with dynamics in the form of strict feed-back affine nonlinearity is addressed.A fixed-time antidistur-bance consensus tracking protocol is proposed,which consists of a distributed fixed-time observer,a fixed-time disturbance observer,a nonsmooth antidisturbance backstepping controller,and the fixed-time stability analysis is conducted by using the Lyapunov theory correspondingly.This paper includes three main improvements.First,a distributed fixed-time observer is developed for each follower to obtain an estimate of the leader’s output by utilizing the topology of the communication network.Second,a fixed-time disturbance observer is given to estimate the lumped disturbances for feedforward compensation.Finally,a nonsmooth antidisturbance backstepping tracking controller with feedforward compensation for lumped disturbances is designed.In order to mitigate the“explosion of complexity”in the tradi-tional backstepping approach,we have implemented a modified nonsmooth command filter to enhance the performance of the closed-loop system.The simulation results show that the pro-posed method is effective. 展开更多
关键词 Antidisturbance BACKSTEPPING consensus tracking fixed-time stability multiagent system(MASs) strict feedback affine nonlinear systems.
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Regression Method for Rail Fastener Tightness Based on Center-Line Projection Distance Feature and Neural Network
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作者 Yuanhang Wang Duxin liu +4 位作者 Sheng Guo Yifan Wu Jing liu wei li Hongjie Wang 《Chinese Journal of Mechanical Engineering》 SCIE EI CAS CSCD 2024年第2期356-371,共16页
In the railway system,fasteners have the functions of damping,maintaining the track distance,and adjusting the track level.Therefore,routine maintenance and inspection of fasteners are important to ensure the safe ope... In the railway system,fasteners have the functions of damping,maintaining the track distance,and adjusting the track level.Therefore,routine maintenance and inspection of fasteners are important to ensure the safe operation of track lines.Currently,assessment methods for fastener tightness include manual observation,acoustic wave detection,and image detection.There are limitations such as low accuracy and efficiency,easy interference and misjudgment,and a lack of accurate,stable,and fast detection methods.Aiming at the small deformation characteristics and large elastic change of fasteners from full loosening to full tightening,this study proposes high-precision surface-structured light technology for fastener detection and fastener deformation feature extraction based on the center-line projection distance and a fastener tightness regression method based on neural networks.First,the method uses a 3D camera to obtain a fastener point cloud and then segments the elastic rod area based on the iterative closest point algorithm registration.Principal component analysis is used to calculate the normal vector of the segmented elastic rod surface and extract the point on the centerline of the elastic rod.The point is projected onto the upper surface of the bolt to calculate the projection distance.Subsequently,the mapping relationship between the projection distance sequence and fastener tightness is established,and the influence of each parameter on the fastener tightness prediction is analyzed.Finally,by setting up a fastener detection scene in the track experimental base,collecting data,and completing the algorithm verification,the results showed that the deviation between the fastener tightness regression value obtained after the algorithm processing and the actual measured value RMSE was 0.2196 mm,which significantly improved the effect compared with other tightness detection methods,and realized an effective fastener tightness regression. 展开更多
关键词 Railway system Fasteners Tightness inspection Neural network regression 3D point cloud processing
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Comparative analysis of thermodynamic and mechanical responses between underground hydrogen storage and compressed air energy storage in lined rock caverns
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作者 Bowen Hu liyuan Yu +5 位作者 Xianzhen Mi Fei Xu Shuchen li wei li Chao wei Tao Zhang 《International Journal of Mining Science and Technology》 SCIE EI CAS CSCD 2024年第4期531-543,共13页
Underground hydrogen storage(UHS)and compressed air energy storage(CAES)are two viable largescale energy storage technologies for mitigating the intermittency of wind and solar power.Therefore,it is meaningful to comp... Underground hydrogen storage(UHS)and compressed air energy storage(CAES)are two viable largescale energy storage technologies for mitigating the intermittency of wind and solar power.Therefore,it is meaningful to compare the properties of hydrogen and air with typical thermodynamic storage processes.This study employs a multi-physical coupling model to compare the operations of CAES and UHS,integrating gas thermodynamics within caverns,thermal conduction,and mechanical deformation around rock caverns.Gas thermodynamic responses are validated using additional simulations and the field test data.Temperature and pressure variations of air and hydrogen within rock caverns exhibit similarities under both adiabatic and diabatic simulation modes.Hydrogen reaches higher temperature and pressure following gas charging stage compared to air,and the ideal gas assumption may lead to overestimation of gas temperature and pressure.Unlike steel lining of CAES,the sealing layer(fibre-reinforced plastic FRP)in UHS is prone to deformation but can effectively mitigates stress in the sealing layer.In CAES,the first principal stress on the surface of the sealing layer and concrete lining is tensile stress,whereas UHS exhibits compressive stress in the same areas.Our present research can provide references for the selection of energy storage methods. 展开更多
关键词 Underground hydrogen storage Compressed air energy storage Mechanical response Thermodynamic response Lined rock caverns
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Adaptive battery thermal management systems in unsteady thermal application contexts
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作者 Kailong liu Qiao Peng +3 位作者 Zhuoran liu wei li Naxin Cui Chenghui Zhang 《Journal of Energy Chemistry》 SCIE EI CAS CSCD 2024年第10期650-668,I0014,共20页
With the increasing attention paid to battery technology,the microscopic reaction mechanism and macroscopic heat transfer process of lithium-ion batteries have been further studied and understood from both academic an... With the increasing attention paid to battery technology,the microscopic reaction mechanism and macroscopic heat transfer process of lithium-ion batteries have been further studied and understood from both academic and industrial perspectives.Temperature,as one of the key parameters in the physical fra mework of batteries,affects the performa nce of the multi-physical fields within the battery,a nd its effective control is crucial.Since the heat generation in the battery is determined by the real-time operating conditions,the battery temperature is essentially controlled by the real-time heat dissipation conditions provided by the battery thermal management system.Conventional battery thermal management systems have basic temperature control capabilities for most conventional application scenarios.However,with the current development of la rge-scale,integrated,and intelligent battery technology,the adva ncement of battery thermal management technology will pay more attention to the effective control of battery temperature under sophisticated situations,such as high power and widely varied operating conditions.In this context,this paper presents the latest advances and representative research related to battery thermal management system.Firstly,starting from battery thermal profile,the mechanism of battery heat generation is discussed in detail.Secondly,the static characteristics of the traditional battery thermal management system are summarized.Then,considering the dynamic requirements of battery heat dissipation under complex operating conditions,the concept of adaptive battery thermal management system is proposed based on specific research cases.Finally,the main challenges for battery thermal management system in practice are identified,and potential future developments to overcome these challenges are presented and discussed. 展开更多
关键词 Lithium-ion batteries Heat generation mechanism Battery thermal management system Cooling methods Battery safety
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Self-templating synthesis of biomass-based porous carbon nanotubes for energy storage and catalytic degradation applications
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作者 Manman Xu Shiqi Fu +7 位作者 Yukai Wen wei li Qiongfang Zhuo Haida Zhu Zhikeng Zheng Yuwen Chen Anqi Wang Kai Yan 《Green Energy & Environment》 SCIE EI CAS CSCD 2024年第3期584-595,共12页
Dwindling energy sources and a worsening environment are huge global problems,and biomass wastes are an under-exploited source of material for both energy and material generation.Herein,self-template decoction dregs o... Dwindling energy sources and a worsening environment are huge global problems,and biomass wastes are an under-exploited source of material for both energy and material generation.Herein,self-template decoction dregs of Ganoderma lucidum-derived porous carbon nanotubes(ST-DDLGCs)were synthesized via a facile and scalable strategy in response to these challenges.ST-DDLGCs exhibited a large surface area(1731.51 m^(2)g^(-1))and high pore volume(0.76 cm^(3)g^(-1)),due to the interlacing tubular structures of precursors and extra-hierarchical porous structures on tube walls.In the ST-DDLGC/PMS system,the degradation efficiency of capecitabine(CAP)reached~97.3%within 120 min.Moreover,ST-DDLGCs displayed high catalytic activity over a wide pH range of 3–9,and strong anti-interference to these typical and ubiquitous anions in wastewater and natural water bodies(i.e.,H_(2)PO_(4)^(-),NO_(3)^(-),Cl^(-) and HCO_(3)^(-)),in which a ^(1)O_(2)-dominated oxidation was identified and non-radical mechanisms were deduced.Additionally,ST-DDLGC-based coin-type symmetrical supercapacitors exhibited outstanding electrochemical performance,with specific capacitances of up to 328.1 F g^(-1)at 0.5 A g^(-1),and cycling stability of up to 98.6%after 10,000 cycles at a current density of 2 A g^(-1).The superior properties of ST-DDLGCs could be attributed to the unique porous tubular structure,which facilitated mass transfer and presented numerous active sites.The results highlight ST-DDLGCs as a potential candidate for constructing inexpensive and advanced environmentally functional materials and energy storage devices. 展开更多
关键词 Ganoderma lucidum residue Porous carbon nanotubes Self-template method Wastewater treatment Supercapacitor electrode
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Effect of Jianpi Shengxue Tablet on Iron Metabolism and Nutritional Status in Patients with Renal Anemia:A Prospective,Randomized,Open,Parallel Controlled and Multicenter Clinical Study
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作者 Juan YANG Meng-yuan liANG +15 位作者 Yu li Hao ZHANG wei li Jing LV li-ping DONG Jing-song JIN Cheng YANG Qing-hong ZHANG li LONG Rong ZOU Yi GAO Dan SONG Chun-qin PAN Ying YAO Xiao-lin ZHAN Xiao-hui WANG 《Current Medical Science》 SCIE CAS 2024年第3期603-610,共8页
Objective This study aimed to analyze the clinical efficacy of the Jianpi Shengxue tablet for treating renal anemia.Methods A total of 200 patients with renal anemia from December 2020 to December 2022 were enrolled a... Objective This study aimed to analyze the clinical efficacy of the Jianpi Shengxue tablet for treating renal anemia.Methods A total of 200 patients with renal anemia from December 2020 to December 2022 were enrolled and randomly divided into two groups.Patients in the control group were treated with polysaccharide-iron complex,and those in the experimental group were administered Jianpi Shengxue tablet.After 8 weeks of continuous treatment,the therapeutic outcomes regarding anemia were compared between the two groups.Results After treatment,the red blood cell(RBC)count,hematocrit(HCT),reticulocyte percentage(RET),ferritin(SF),serum iron(SI),transferrin saturation(TSAT),and serum albumin(ALB)all increased(P<0.01),and the clinical symptom score and total iron binding capacity decreased(P<0.01)in the experimental group.Moreover,the improvements in RBC,HCT,RET,SF,SI,TAST,ALB,and clinical symptoms(fatigue,anorexia,dull skin complexion,numbness of hands and feet)in the experimental group were significantly greater than those in the control group(P<0.05).The total effective rate for treating renal anemia was significantly higher in the experimental group than in the control group(P<0.01).Conclusion The Jianpi Shengxue tablet demonstrates efficacy in treating renal anemia,leading to significant improvements in the laboratory examination results and clinical symptoms of patients with renal anemia. 展开更多
关键词 Jianpi Shengxue tablet renal anemia RANDOMIZED OPEN parallel control multicenter clinical study
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Elimination of GGTA1,CMAH,β4GalNT2 and CIITA genes in pigs compromises human versus pig xenogeneic immune reactions
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作者 Jing Xu Jilong Ren +11 位作者 Kai Xu Minghui Fang Meina Ka Fei Xu Xin Wang Jing Wang Zhiqiang Han Guihai Feng Ying Zhang Tang Hai wei li Zheng Hu 《Animal Models and Experimental Medicine》 CAS CSCD 2024年第4期584-590,共7页
Background:Pig organ xenotransplantation is a potential solution for the severe organ shortage in clinic,while immunogenic genes need to be eliminated to improve the immune compatibility between humans and pigs.Curren... Background:Pig organ xenotransplantation is a potential solution for the severe organ shortage in clinic,while immunogenic genes need to be eliminated to improve the immune compatibility between humans and pigs.Current knockout strategies are mainly aimed at the genes causing hyperacute immune rejection(HAR)that occurs in the first few hours while adaptive immune reactions orchestrated by CD4 T cell thereafter also cause graft failure,in which process the MHCⅡmolecule plays critical roles.Methods:Thus,we generate a 4-gene(GGTA1,CMAH,β4GalNT2,and CIITA)knockout pig by CRISPR/Cas9 and somatic cell nuclear transfer to compromise HAR and CD4 T cell reactions simultaneously.Results:We successfully obtained 4KO piglets with deficiency in all alleles of genes,and at cellular and tissue levels.Additionally,the safety of our animals after gene editing was verified by using whole-genome sequencing and karyotyping.Piglets have survived for more than one year in the barrier,and also survived for more than 3 months in the conventional environment,suggesting that the piglets without MHCⅡcan be raised in the barrier and then gradually mated in the conventional environment.Conclusions:4KO piglets have lower immunogenicity,are safe in genomic level,and are easier to breed than the model with both MHCⅠandⅡdeletion. 展开更多
关键词 CD4 T cell genetically edited pig immune rejection major histocompatibility complex II XENOTRANSPLANTATION
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Performance enhancement and active sites identification of Cu-Cd bimetallic oxide derived catalysts for electrochemical CO_(2) reduction
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作者 Cai Wang Xin Hu +7 位作者 Bairong Chen Houan Ren Xiaoyu Wang Yilin Zhang Xinyu Chen Yuping liu Qingxin Guan wei li 《Journal of Energy Chemistry》 SCIE EI CAS CSCD 2024年第4期50-58,共9页
The development of earth-abundant electrocatalysts with high performance for electrochemical CO_(2)reduction(ECR)is of great significance.Cu-based catalysts have been widely investigated for ECR due to their unique ab... The development of earth-abundant electrocatalysts with high performance for electrochemical CO_(2)reduction(ECR)is of great significance.Cu-based catalysts have been widely investigated for ECR due to their unique ability to generate various carbonaceous products,but directing selectivity toward one certain product and identifying the real active sites during ECR are still full of challenge.Here,after the incorporation of CdO into CuO,the Cu_(0.5)Cd_(0.5)-O catalyst achieves a 10.3-fold enhancement for CO selectivity in comparison with CuO,and a CO faradic efficiency nearly 90%with a current density around20 mA cm^(-2)could maintain at least 60 h.Interestingly,a wide CO/H_(2)ratio(0.07-10)is reached on Cu_(x)Cd_(1-x)-O catalysts by varying the Cu/Cd ratio,demonstrating the potential of syngas production using such catalysts.The results of ex situ XRD,XPS,and in situ Raman reveal that the real active sites of Cu_(0.5)Cd_(0.5)-O catalysts for CO production during ECR reaction are the reconstructed mixed phases of CuCd alloy and CdCO_(3).In situ FTIR and theoretical calculations further implicate the presence of Cd related species promotes the CO desorption and inhibits the H_(2)evolution,thus leading to an enhanced CO generation. 展开更多
关键词 CO_(2)reduction Cu-Cd bimetallic Real active sites CO production
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Shenqi Fuzheng injection alleviates chemotherapy-induced cachexia by restoring glucocorticoid signaling in hypothalamus
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作者 Entezar Berik Zijia Zhang +16 位作者 wei li Yawen liu Sihan Chen Wenyong Wu Zhaojun Wang Xinqin Kong Wenqiang Pei Huiqing Dong Huali Long Min Lei Jennifer Yiyang Wang liangfeng liu Jinjun Hou Jing Feng Zhaoxia li Wanying Wu De-an Guo 《Journal of Pharmaceutical Analysis》 SCIE CAS CSCD 2024年第3期431-434,共4页
Chemotherapy-induced cachexia(CIC)is a debilitating condition characterized by weight loss,muscle atrophy,and anorexia[1].While peripheral mechanisms of cachexia have been extensively studied,the involvement of the ce... Chemotherapy-induced cachexia(CIC)is a debilitating condition characterized by weight loss,muscle atrophy,and anorexia[1].While peripheral mechanisms of cachexia have been extensively studied,the involvement of the central nervous system(CNS)in CIC is often overlooked.Chemotherapeutic drugs cause stress responses and inflammation,which may impact the hypothalamus and disrupt systemic energy and neuroendocrine functions.Understanding hypothalamic roles in regulating these processes can provide insights into CIC's mechanisms and aid in developing novel therapies. 展开更多
关键词 injection DRUGS GLUCOCORTICOID CHEMOTHERAPY
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Predict the evolution of mechanical property of Al-Li alloys in a marine environment
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作者 wei li lin Xiang +6 位作者 Guang Wu Hongli Si Jinyan Chen Yiming Jin Yan Su Jianquan Tao Chunyang Huang 《Defence Technology(防务技术)》 SCIE EI CAS CSCD 2024年第1期557-566,共10页
The ocean is one of the essential fields of national defense in the future,and more and more attention is paid to the lightweight research of Marine equipment and materials.This study it is to develop a Machine learni... The ocean is one of the essential fields of national defense in the future,and more and more attention is paid to the lightweight research of Marine equipment and materials.This study it is to develop a Machine learning(ML)-based prediction method to study the evolution of the mechanical properties of Al-Li alloys in the marine environment.We obtained the mechanical properties of Al-Li alloy samples under uniaxial tensile deformation at different exposure times through Marine exposure experiments.We obtained the strain evolution by digital image correlation(DIC).The strain field images are voxelized using 2D-Convolutional Neural Networks(CNN)autoencoders as input data for Long Short-Term Memory(LSTM)neural networks.Then,the output data of LSTM neural networks combined with corrosion features were input into the Back Propagation(BP)neural network to predict the mechanical properties of Al-Li alloys.The main conclusions are as follows:1.The variation law of mechanical properties of2297-T8 in the Marine atmosphere is revealed.With the increase in outdoor exposure test time,the tensile elastic model of 2297-T8 changes slowly,within 10%,and the tensile yield stress changes significantly,with a maximum attenuation of 23.6%.2.The prediction model can predict the strain evolution and mechanical response simultaneously with an error of less than 5%.3.This study shows that a CNN/LSTM system based on machine learning can be built to capture the corrosion characteristics of Marine exposure experiments.The results show that the relationship between corrosion characteristics and mechanical response can be predicted without considering the microstructure evolution of metal materials. 展开更多
关键词 Marine environment Al-Li alloy Machine learning CORROSION
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Application of the finite analytic numerical method to a flowdependent variational data assimilation
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作者 Yan Hu wei li +2 位作者 Xuefeng Zhang Guimei liu liang Zhang 《Acta Oceanologica Sinica》 SCIE CAS CSCD 2024年第3期30-39,共10页
An anisotropic diffusion filter can be used to model a flow-dependent background error covariance matrix,which can be achieved by solving the advection-diffusion equation.Because of the directionality of the advection... An anisotropic diffusion filter can be used to model a flow-dependent background error covariance matrix,which can be achieved by solving the advection-diffusion equation.Because of the directionality of the advection term,the discrete method needs to be chosen very carefully.The finite analytic method is an alternative scheme to solve the advection-diffusion equation.As a combination of analytical and numerical methods,it not only has high calculation accuracy but also holds the characteristic of the auto upwind.To demonstrate its ability,the one-dimensional steady and unsteady advection-diffusion equation numerical examples are respectively solved by the finite analytic method.The more widely used upwind difference method is used as a control approach.The result indicates that the finite analytic method has higher accuracy than the upwind difference method.For the two-dimensional case,the finite analytic method still has a better performance.In the three-dimensional variational assimilation experiment,the finite analytic method can effectively improve analysis field accuracy,and its effect is significantly better than the upwind difference and the central difference method.Moreover,it is still a more effective solution method in the strong flow region where the advective-diffusion filter performs most prominently. 展开更多
关键词 finite analytic method advection-diffusion equation data assimilation flow-dependent
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