Conventional method for hose-drogue model of aerial refueling system is known to be complex due to the flexible body of hose.And as reported,drogues are unstable in atmospheric turbulence,which greatly decreases docki...Conventional method for hose-drogue model of aerial refueling system is known to be complex due to the flexible body of hose.And as reported,drogues are unstable in atmospheric turbulence,which greatly decreases docking success rates.This paper proposes a dynamic model for a hose-drogue aerial refueling system based on Kane equation and rigid multi-body dynamics,and analyzes its performance.Furthermore,the nonlinear dynamic model is linearized at the equilibrium point and simplified from full order to 2 nd order.Based on the simplified 2 nd order model,active control strategies,including proportion integral derivative(PID)and liner quadratic regulator(LQR)control laws,are designed to inhibit the pendulum movement of drogue due to,atmospheric turbulences.Numerical simulation results show the significant correctness of the proposed dynamic model by steady-state drag and balance position of drogue when the tanker flights under different conditions.Moreover,the steady state position error varies within 1 cm,thanks to either controller,when the drogue suffers from moderate-level atmospheric turbulences.Further,the PID controller exhibits better control effect and higher control precision than LQR controller.展开更多
目的探讨血清高迁移率族蛋白B1(high mobility group protein B1,HMGB1)、可溶性髓系细胞触发受体1(soluble myeloid cell trigger receptor-1,sTREM-1)联合检测对脓毒症并发急性肾损伤(acute kidney injury,AKI)的诊断价值。方法回顾...目的探讨血清高迁移率族蛋白B1(high mobility group protein B1,HMGB1)、可溶性髓系细胞触发受体1(soluble myeloid cell trigger receptor-1,sTREM-1)联合检测对脓毒症并发急性肾损伤(acute kidney injury,AKI)的诊断价值。方法回顾性选择徐州市中心医院2020年1月1日至2022年1月31日收治的156例脓毒症患者,另选取同期68例体检健康者为对照组。对比两组受试者血清HMGB1、sTREM-1水平,多因素Logistic回归分析脓毒症并发AKI的影响因素,受试者工作特征曲线分析血清HMGB1、sTREM-1水平对脓毒症并发AKI的诊断价值。结果脓毒症组患者血清HMGB1[172530(133870,204010)ng/L比83720(63480,99870)ng/L]、sTREM-1[(49.56±8.03)ng/L比(24.96±5.24)ng/L]水平明显高于对照组(P<0.05);多因素Logistic分析显示,血肌酐(OR=1.079,95%CI:1.037~1.122)、HMGB1(OR=1.933,95%CI:1.376~2.714)、sTREM-1(OR=1.201,95%CI:1.101~1.309)为脓毒症并发AKI的独立危险因素(P<0.05);受试者工作特征曲线显示,HMGB1联合sTREM-1[曲线下面积(area under the curve,AUC)=0.928,95%CI:0.876~0.963]诊断脓毒症并发AKI的敏感度、特异度、准确度高于HMGB1(AUC=0.790,95%CI:0.718~0.851)、sTREM-1(AUC=0.778,95%CI:0.705~0.840)诊断。结论脓毒症患者血清HMGB1、sTREM-1水平明显增高,是脓毒症并发AKI的独立危险因素。展开更多
基金supported in part by the National Natural Science Foundation of China(No.61533008)the Fundamental Research Funds for the Central Universities(No. NZ2016104)the Funding of Jiangsu Innovation Program for Graduate Education(No.KYLX15_0276)
文摘Conventional method for hose-drogue model of aerial refueling system is known to be complex due to the flexible body of hose.And as reported,drogues are unstable in atmospheric turbulence,which greatly decreases docking success rates.This paper proposes a dynamic model for a hose-drogue aerial refueling system based on Kane equation and rigid multi-body dynamics,and analyzes its performance.Furthermore,the nonlinear dynamic model is linearized at the equilibrium point and simplified from full order to 2 nd order.Based on the simplified 2 nd order model,active control strategies,including proportion integral derivative(PID)and liner quadratic regulator(LQR)control laws,are designed to inhibit the pendulum movement of drogue due to,atmospheric turbulences.Numerical simulation results show the significant correctness of the proposed dynamic model by steady-state drag and balance position of drogue when the tanker flights under different conditions.Moreover,the steady state position error varies within 1 cm,thanks to either controller,when the drogue suffers from moderate-level atmospheric turbulences.Further,the PID controller exhibits better control effect and higher control precision than LQR controller.
文摘目的探讨血清高迁移率族蛋白B1(high mobility group protein B1,HMGB1)、可溶性髓系细胞触发受体1(soluble myeloid cell trigger receptor-1,sTREM-1)联合检测对脓毒症并发急性肾损伤(acute kidney injury,AKI)的诊断价值。方法回顾性选择徐州市中心医院2020年1月1日至2022年1月31日收治的156例脓毒症患者,另选取同期68例体检健康者为对照组。对比两组受试者血清HMGB1、sTREM-1水平,多因素Logistic回归分析脓毒症并发AKI的影响因素,受试者工作特征曲线分析血清HMGB1、sTREM-1水平对脓毒症并发AKI的诊断价值。结果脓毒症组患者血清HMGB1[172530(133870,204010)ng/L比83720(63480,99870)ng/L]、sTREM-1[(49.56±8.03)ng/L比(24.96±5.24)ng/L]水平明显高于对照组(P<0.05);多因素Logistic分析显示,血肌酐(OR=1.079,95%CI:1.037~1.122)、HMGB1(OR=1.933,95%CI:1.376~2.714)、sTREM-1(OR=1.201,95%CI:1.101~1.309)为脓毒症并发AKI的独立危险因素(P<0.05);受试者工作特征曲线显示,HMGB1联合sTREM-1[曲线下面积(area under the curve,AUC)=0.928,95%CI:0.876~0.963]诊断脓毒症并发AKI的敏感度、特异度、准确度高于HMGB1(AUC=0.790,95%CI:0.718~0.851)、sTREM-1(AUC=0.778,95%CI:0.705~0.840)诊断。结论脓毒症患者血清HMGB1、sTREM-1水平明显增高,是脓毒症并发AKI的独立危险因素。
