Through dynamically monitoring changes of acute mountain sickness(AMS)occurrences,cardiopulmonary function and mood states from Shanghai(4 m)to Lhasa(3650 m)and Yambajan(4300 m),Tibet,we obtained physiopsychological d...Through dynamically monitoring changes of acute mountain sickness(AMS)occurrences,cardiopulmonary function and mood states from Shanghai(4 m)to Lhasa(3650 m)and Yambajan(4300 m),Tibet,we obtained physiopsychological data of the 37th Chinese Antarctic pre-selected expeditioners for Kunlun Station.Through analyzing different physiopsychological changes between AMS-susceptible(AMS-S)and AMS-resistant(AMS-R)expeditioners,we would explore indicators to screen hypoxia-susceptible expeditioners.According to AMS occurrences evaluated by Lake Louise Score(LLS)in Yambajan,we divided the expeditioners(n=24,31.92±5.76 a)into AMS-S and AMS-R groups.Using a series of medical instrumentsand questionnaires,we monitored their cardiopulmonary function and mood states,and analyzed the differences of physiopsychological parameters between AMS-S and AMS-R groups.Compared with Shanghai,when expeditioners arrived in Yambajan,in both AMS-S and AMS-R groups,oxygen saturation(SpO2)significantly decreased,and blood pressure significantly increased(P<0.05).As for electrocardiogram(ECG),interval from the beginning to the end of QRS complex wave(QRS),interval from the beginning of QRS complex wave to the end of T wave(QT),interval between 2 adjacent P waves(PP)and interval between 2 adjacent R waves(RR)significantly decreased,heart rate(HR)and HR-corrected QT interval(QTc)significantly increased(P<0.05).Cardiac contractility and pumping function significantly decreased,systemic vascular resistance significantly increased(P<0.05).Pulmonary airway patency significantly increased(P<0.05).Compared with AMS-R group,AMS-S group showed significantly lower SpO2 and higher stroke volume variation(SVV)in Shanghai,however,significantly lower maximal expiratory flow at 75%of forced vital capacity(MEF75),higher levels of anxiety,fatigue and confusion in Yambajan(P<0.05).In conclusion,when expeditioners arrived at 4300 m,their cardiopulmonary function and mood states changed significantly.SpO2,SVV,MEF75,anxiety,fatigue and confusion maybe could be used as clues for screening hypoxia-susceptible individuals.展开更多
The traditional method for sulfur isotope measurement using EA-IRMS commonly requires sulfur content greater than 2 μmol. Such a large sample size limits its application to low-S materials, the size mainly being due ...The traditional method for sulfur isotope measurement using EA-IRMS commonly requires sulfur content greater than 2 μmol. Such a large sample size limits its application to low-S materials, the size mainly being due to ineffective utilization of sample gas, almost 99.7% of which is discarded with carrier gas through the split port of the continuous-flow interface. A modified EA-IRMS system with a gas chromatographic(GC) column and a custom-built cryogenic concentration device is used in this study. We measured six reference materials to test the performance of this method. The results were consistent with those obtained through traditional EA-IRMS. Precisions ranging from ±0.24‰ to ±0.76‰(1σ)can be obtained with samples equivalent to ~80 nmol sulfur, which were similar to results obtained from an alternative method using an absorption column. Our improved method is a powerful tool for sulfur isotope measurement in ultrasmall sulfide and sulfate samples, which can be further applied to carbon, nitrogen and oxygen isotope analyses of samples at about 100 nmol level.展开更多
Regarding the performance of traditional endpoint detection algorithms degrades as the environment noise level increases, a recursive calculating algorithm for higher-order cu- mulants over a sliding window is propose...Regarding the performance of traditional endpoint detection algorithms degrades as the environment noise level increases, a recursive calculating algorithm for higher-order cu- mulants over a sliding window is proposed. Then it is applied to the speech endpoint detection. Furthermore, endpoint detection is carried out with the feature of energy. Experimental results show that both the computational efficiency and the robustness against noise of the proposed algorithm are improved remarkably compared with traditional algorithm. The average prob- ability of correct point detection （Pc-point） of the proposed voice activity detection （VAD） is 6.07% higher than that of G.729b VAD in different noisy at different signal-noise ratios （SNRs） environments.展开更多
基金funded by the CAA(Grant no.JDXT2019-03)the National Antarctic Expedition Training Base of China(Medical Monitoring and Screening of the 37th Chinese Antarctic Pre-selected Expeditioners of Kunlun Station During Plateau Adaptive Training in Tibet)the CAA(Formulation of Technical Specifications for Physiological Health Monitoring of Antarctic Expeditioners).
文摘Through dynamically monitoring changes of acute mountain sickness(AMS)occurrences,cardiopulmonary function and mood states from Shanghai(4 m)to Lhasa(3650 m)and Yambajan(4300 m),Tibet,we obtained physiopsychological data of the 37th Chinese Antarctic pre-selected expeditioners for Kunlun Station.Through analyzing different physiopsychological changes between AMS-susceptible(AMS-S)and AMS-resistant(AMS-R)expeditioners,we would explore indicators to screen hypoxia-susceptible expeditioners.According to AMS occurrences evaluated by Lake Louise Score(LLS)in Yambajan,we divided the expeditioners(n=24,31.92±5.76 a)into AMS-S and AMS-R groups.Using a series of medical instrumentsand questionnaires,we monitored their cardiopulmonary function and mood states,and analyzed the differences of physiopsychological parameters between AMS-S and AMS-R groups.Compared with Shanghai,when expeditioners arrived in Yambajan,in both AMS-S and AMS-R groups,oxygen saturation(SpO2)significantly decreased,and blood pressure significantly increased(P<0.05).As for electrocardiogram(ECG),interval from the beginning to the end of QRS complex wave(QRS),interval from the beginning of QRS complex wave to the end of T wave(QT),interval between 2 adjacent P waves(PP)and interval between 2 adjacent R waves(RR)significantly decreased,heart rate(HR)and HR-corrected QT interval(QTc)significantly increased(P<0.05).Cardiac contractility and pumping function significantly decreased,systemic vascular resistance significantly increased(P<0.05).Pulmonary airway patency significantly increased(P<0.05).Compared with AMS-R group,AMS-S group showed significantly lower SpO2 and higher stroke volume variation(SVV)in Shanghai,however,significantly lower maximal expiratory flow at 75%of forced vital capacity(MEF75),higher levels of anxiety,fatigue and confusion in Yambajan(P<0.05).In conclusion,when expeditioners arrived at 4300 m,their cardiopulmonary function and mood states changed significantly.SpO2,SVV,MEF75,anxiety,fatigue and confusion maybe could be used as clues for screening hypoxia-susceptible individuals.
基金supported by the National Natural Science Foundation of China (Grant Nos. 41627802 and 41973022)the Central Public-interest Scientific Institution Basal Research Fund (Grant No. YYWF201710)。
文摘The traditional method for sulfur isotope measurement using EA-IRMS commonly requires sulfur content greater than 2 μmol. Such a large sample size limits its application to low-S materials, the size mainly being due to ineffective utilization of sample gas, almost 99.7% of which is discarded with carrier gas through the split port of the continuous-flow interface. A modified EA-IRMS system with a gas chromatographic(GC) column and a custom-built cryogenic concentration device is used in this study. We measured six reference materials to test the performance of this method. The results were consistent with those obtained through traditional EA-IRMS. Precisions ranging from ±0.24‰ to ±0.76‰(1σ)can be obtained with samples equivalent to ~80 nmol sulfur, which were similar to results obtained from an alternative method using an absorption column. Our improved method is a powerful tool for sulfur isotope measurement in ultrasmall sulfide and sulfate samples, which can be further applied to carbon, nitrogen and oxygen isotope analyses of samples at about 100 nmol level.
基金supported by the National Natural Science Eoundation of China(61271352)
文摘Regarding the performance of traditional endpoint detection algorithms degrades as the environment noise level increases, a recursive calculating algorithm for higher-order cu- mulants over a sliding window is proposed. Then it is applied to the speech endpoint detection. Furthermore, endpoint detection is carried out with the feature of energy. Experimental results show that both the computational efficiency and the robustness against noise of the proposed algorithm are improved remarkably compared with traditional algorithm. The average prob- ability of correct point detection （Pc-point） of the proposed voice activity detection （VAD） is 6.07% higher than that of G.729b VAD in different noisy at different signal-noise ratios （SNRs） environments.
