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Expediting Should Be Emphasized in B&R Engineering Construction
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作者 weilun zhang 《China's Foreign Trade》 2019年第3期50-50,共1页
Expediting is becoming more essential with the increase of engineering construction projects by Chinese companies abroad.According to Xinhua News Agency,from 2013 to 2018,Chinese enterprises’direct investment in coun... Expediting is becoming more essential with the increase of engineering construction projects by Chinese companies abroad.According to Xinhua News Agency,from 2013 to 2018,Chinese enterprises’direct investment in countries along the Belt and Road(B&R)exceeded USD 90 billion,with an average annual growth rate of 5.2%.For countries along B&R,the value of Engineering Procurement Construction(EPC)projects signed with Chinese companies exceeded USD 600 billion,which is an average annual increase of 11.9%. 展开更多
关键词 EPC Expediting SHOULD BE Emphasized in B&R ENGINEERING CONSTRUCTION
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双子季铵盐氯胺的合成及抗菌应用
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作者 李令东 张维伦 +3 位作者 刘鹏飞 周子杰 周豪 杜中田 《有机化学》 SCIE CAS CSCD 北大核心 2024年第6期2041-2048,共8页
以5,5-二甲基海因为原料,通过多步合成策略制备了一系列不同长度spacer的双子(Gemini)季铵盐氯胺抗菌剂N,N-双(3-(3-氯-4,4-二甲基-2,5-二氧亚基咪唑烷-1-基)丙基)-N,N,N,N-四甲基丁烷-1,4-二铵氯化物(6)~N,N-双(3-(3-氯-4,4-二甲基-2,5... 以5,5-二甲基海因为原料,通过多步合成策略制备了一系列不同长度spacer的双子(Gemini)季铵盐氯胺抗菌剂N,N-双(3-(3-氯-4,4-二甲基-2,5-二氧亚基咪唑烷-1-基)丙基)-N,N,N,N-四甲基丁烷-1,4-二铵氯化物(6)~N,N-双(3-(3-氯-4,4-二甲基-2,5-二氧亚基咪唑烷-1-基)丙基)-N,N,N,N-四甲基癸烷-1,10-二铵氯化物(9),采用核磁共振波谱(NMR)和高分辨质谱(HRMS)表征了前体和氯胺结构.以E.coli(ATCC 25922)和S.aureus(ATCC 25923)为模式菌株,以已报道的Gemini-季铵盐氯胺5为对照,初步测试了氯胺6~9抗菌活性.抗菌数据表明,5~9抗菌活性随结构中spacer增大呈现了先减弱后增强的趋势,其中spacer为C10H20的氯胺9抗菌活性达到了最佳,明显优于具有“团队”抗菌效应的5~6,这可能是9达到了分子触杀所需最佳的亲疏水平衡状态所致.表明spacer大小决定了“团队”协同抗菌作用的强弱,且双亲氯胺亲疏水状态对分子触杀贡献极大.合成了一系列高效阳离子型氯胺抗菌剂,为今后更高效氯胺抗菌剂研发提供重要参考. 展开更多
关键词 双子季铵盐氯胺 化学多步合成 抗菌活性 亲疏水平衡 “团队”抗菌效应
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A Refueling Scheme Optimization Model for the Voyage Charter with Fuel Price Fluctuation and Ship Deployment Consideration
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作者 Peng JIA weilun zhang +1 位作者 Wenhao E Xueshan SUN 《Journal of Systems Science and Information》 CSCD 2017年第3期267-278,共12页
Due to the long operation cycle of maritime transportation and frequent fluctuations of the bunker fuel price, the refueling expenditure of a chartered ship at different time or ports of call make significant differen... Due to the long operation cycle of maritime transportation and frequent fluctuations of the bunker fuel price, the refueling expenditure of a chartered ship at different time or ports of call make significant difference. From the perspective of shipping company, an optimal set of refueling schemes for a ship fleet operating on different voyage charter routes is an important decision. To address this issue, this paper presents an approach to optimize the refueling scheme and the ship deployment simultaneously with considering the trend of fuel price fluctuations. Firstly, an ARMA model is applied to forecast a time serials of the fuel prices. Then a mixed-integer nonlinear programming model is proposed to maximize total operating profit of the shipping company. Finally, a case study on a charter company with three bulk carriers and three voyage charter routes is conducted. The results show that the optimal solution saves the cost of 437,900 USD compared with the traditional refueling scheme, and verify the rationality and validity of the model. 展开更多
关键词 voyage charter refueling scheme optimization ship deployment bunker fuel price prediction
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