Effect of early stepwise cardiopulmonary rehabilitation on function and quality of life in sepsis patients

BACKGROUND Sepsis,as a non-limiting host infection disease,can be accompanied by serious complications such as organ failure,which seriously threatens patient quality of life.AIM To investigate the effect of early stepwise cardiopulmonary rehabilitation on cardiopulmonary function and quality of life in patients evacuated from mechanical ventilation with sepsis.METHODS A total of 80 patients with sepsis who were hospitalized in our hospital from January 2021 to January 2022 were selected and divided into the observation group(n=40)and the control group(n=40)according to the random number table method.The observation group was treated with early stepwise cardiopulmonary rehabilitation,and the control group was treated with a conventional treatment regimen.Cardiac function indexes(central venous pressure,cardiac troponin I,B-type brain natriuretic peptide),lung function indicators(diaphragmatic mobility,changes in central venous oxygen saturation,oxygenation index),and quality of life(Quality of Life Evaluation Scale)were compared between the two groups after treatment.RESULTS After treatment,the central venous pressure,diaphragm mobility,central venous oxygen saturation,oxygenation index,and Quality of Life Evaluation Scale scores in the observation group were higher than those in the control group,and the differences were statistically significant(P<0.05).The observation group was less than that of the control group for other parameters,and the differences were statistically significant(P<0.05).CONCLUSION Early stepwise cardiopulmonary rehabilitation can effectively enhance cardiac and pulmonary function and improve the quality of life in patients evacuated from mechanical ventilation with sepsis.

High-performance amorphous In–Ga–Zn–O thin-film transistor nonvolatile memory with a novel p-SnO/n-SnO_(2) heterojunction charge trapping stack

Amorphous In–Ga–Zn–O(a-IGZO)thin-film transistor(TFT)memories with novel p-SnO/n-SnO_(2) heterojunction charge trapping stacks(CTSs)are investigated comparatively under a maximum fabrication temperature of 280℃.Compared to a single p-SnO or n-SnO_(2) charge trapping layer(CTL),the heterojunction CTSs can achieve electrically programmable and erasable characteristics as well as good data retention.Of the two CTSs,the tunneling layer/p-SnO/nSnO_(2)/blocking layer architecture demonstrates much higher program efficiency,more robust data retention,and comparably superior erase characteristics.The resulting memory window is as large as 6.66 V after programming at 13 V/1 ms and erasing at-8 V/1 ms,and the ten-year memory window is extrapolated to be 4.41 V.This is attributed to shallow traps in p-SnO and deep traps in n-SnO_(2),and the formation of a built-in electric field in the heterojunction.

Ultrafast Fiber Laser Based on Tungsten Sulphoselenide Materials

Tungsten sulphoselenide(WSSe) alloys, belonging to the transition metal dichalcogenide family, have attracted significant interest in the area of optoelectronics because of their unique optical and electronic properties.However, there has been a dearth of sufficient research on the saturable absorption features and ultrafast lasers applications. Herein, we fabricated a WSSe-microfiber saturable absorber(SA) based on WSSe nanosheets prepared by liquid exfoliation technique. The SA provided a saturation intensity of a modulation depth of 27.95%and a nonsaturable loss of 21.34%. To investigate the potential applications of WSSe in ultrafast photonics, the prepared WSSe-microfiber was incorporated into an Er-doped fiber laser ring cavity. The results demonstrated that the WSSe-based SA successfully generated mode-locking laser pulses with a remarkably short pulse width of 231 fs. Furthermore, the output power of this ultrafast fiber laser reached an impressive value of 15.68 mW.These findings provide valuable views into the unique features of WSSe alloys in the areas of ultrafast optics and develop recipes for SA in ultrafast fiber lasers.

慢性丙型肝炎病毒患者APRI评分与肝功能、凝血功能的相关性

目的探讨不同程度肝损伤慢性丙型肝炎病毒(HCV)患者天门冬氨酸氨基转移酶与血小板比值(APRI)评分、肝功能及凝血功能之间的关系。方法检测受试者的肝功能、血小板及凝血功能指标,计算APRI评分,对相关指标进行比较分析。结果 HCV组患者血浆纤维蛋白原(FIB)、APRI评分、总胆红素(TBIL)、γ-谷氨酰转肽酶(γ-GT)、活化部分凝血活酶时间(APTT)、凝血酶原时间(PT)、凝血酶时间(TT)及D二聚体(D-D)水平与健康体检组比较有差异(P<0.05)。患者TBIL、γ-GT、APTT、PT及TT与APRI评分呈正相关(P<0.05),FIB与APRI评分呈负相关(P<0.05)。结论慢性HCV患者肝功能、凝血功能与APRI评分相关,对评估慢性HCV患者肝损伤趋势有重要意义。

MoS_2 saturable absorber prepared by chemical vapor deposition method for nonlinear control in Q-switching fiber laser

Due to the remarkable carrier mobility and nonlinear characteristic, MoS2 is considered to be a powerful competitor as an effective optical modulated material in fiber lasers. In this paper, the MoS2 films are prepared by the chemical vapor deposition method to guarantee the high quality of the crystal lattice and uniform thickness. The transfer of the films to microfiber and the operation of gold plated films ensure there is no heat-resistant damage and anti-oxidation. The modulation depth of the prepared integrated microfiber-MoS2 saturable absorber is 11.07%. When the microfiber-MoS2 saturable absorber is used as a light modulator in the Q-switching fiber laser, the stable pulse train with a pulse duration of 888 ns at 1530.9 nm is obtained. The ultimate output power and pulse energy of output pulses are 18.8 mW and 88 nJ, respectively. The signal-to-noise ratio up to 60 dB indicates the good stability of the laser. This work demonstrates that the MoS2 saturable absorber prepared by the chemical vapor deposition method can serve as an effective nonlinear control device for the Q-switching fiber laser.

Stable soliton propagation in a coupled (2+1) dimensional Ginzburg-Landau system

A coupled(2+1)-dimensional variable coefficient Ginzburg-Landau equation is studied.By virtue of the modified Hirota bilinear method,the bright one-soliton solution of the equation is derived.Some phenomena of soliton propagation are analyzed by setting different dispersion terms.The influences of the corresponding parameters on the solitons are also discussed.The results can enrich the soliton theory,and may be helpful in the manufacture of optical devices.

Soliton fusion and fission for the high-order coupled nonlinear Schr?dinger system in fiber lasers

With the rapid development of communication technology,optical fiber communication has become a key research area in communications.When there are two signals in the optical fiber,the transmission of them can be abstracted as a high-order coupled nonlinear Schr¨odinger system.In this paper,by using the Hirota’s method,we construct the bilinear forms,and study the analytical solution of three solitons in the case of focusing interactions.In addition,by adjusting different wave numbers for phase control,we further discuss the influence of wave numbers on soliton transmissions.It is verified that wave numbers k_(11),k_(21),k_(31),k_(22),and k_(32)can control the fusion and fission of solitons.The results are beneficial to the study of all-optical switches and fiber lasers in nonlinear optics.

Photoresponsive characteristics of thin film transistors with perovskite quantum dots embedded amorphous InGaZnO channels

Photodetectors based on amorphous InGaZnO(a-IGZO)thin film transistor(TFT)and halide perovskites have attracted attention in recent years.However,such a stack assembly of a halide perovskite layer/an a-IGZO channel,even with an organic semiconductor film inserted between them,easily has a very limited photoresponsivity.In this article,we investigate photoresponsive characteristics of TFTs by using CsPbX3(X=Br or I)quantum dots(QDs)embedded into the a-IGZO channel,and attain a high photoresponsivity over 10^3A·W^-1,an excellent detectivity in the order of 10^16 Jones,and a light-to-dark current ratio up to 10^5 under visible lights.This should be mainly attributed to the improved transfer efficiency of photoelectrons from the QDs to the a-IGZO channel.Moreover,spectrally selective photodetection is demonstrated by introducing halide perovskite QDs with different bandgaps.Thus,this work provides a novel strategy of device structure optimization for significantly improving the photoresponsive characteristics of TFT photodetectors.

Soliton Rectangular Pulses and Bound States in a Dissipative System Modeled by the Variable-Coefficients Complex Cubic-Quintic Ginzburg-Landau Equation

The complex cubic-quintic Ginzburg-Landau equation(CQGLE)is a universal model for describing a dissipative system,especially fiber laser.The analytic one-soliton solution of the variable-coefficients CQGLE is calculated by a modified Hirota method.Then,phenomena of soliton pulses splitting and stable bound states of two solitons are investigated.Moreover,rectangular dissipative soliton pulses of the variable-coefficients CQGLE are realized and controlled effectively in the theoretical research for the first time,which breaks through energy limitation of soliton pulses and is expected to provide theoretical basis for preparation of high-energy soliton pulses in fiber lasers.

Band Alignment at the Al2O3/β-Ga2O3 Interface with CHF3 Treatment

The energy band alignment at the atomic layer deposited Al2O3/β-Ga2O3 interface with CHF3 treatment was characterized by x-ray photoelectron spectroscopy and secondary ion mass spectrometry(SIMS).With additional CHF3 plasma treatment,the conduction band offset increases from 1.95±0.1 eV to 2.32±0.1 eV;and the valence band offset decreases from 0.21±0.1 eV to-0.16±0.1 eV.As a result,the energy band alignment changes from type I to type II.This energy band alignment transition could be attributed to the downshift of the core-level of Ga 3d,resulting from the Ga–F bond formation in the F-rich interfacial layer,which is confirmed by the SIMS results.

Effect of Danhong injection on neuroendocrine molecules and ventricular remodeling in patients with ischemic cardiomyopathy heart failure

Objective:To study the effect of Danhong injection on neuroendocrine molecules and ventricular remodeling in patients with ischemic cardiomyopathy heart failure.Methods: 80 cases of patients with ischemic cardiomyopathy heart failure who were treated in our hospital between March 2014 and December 2016 were collected and divided into control group (n=40) and observation group (n=40) according to random number table. The control group received regular treatment, the observation group received regular + Danhong injection treatment, and both therapies lasted for 14 d a course, two sessions. Serum contents of neuroendocrine molecules and ventricular remodeling-related indexes, Doppler ultrasonic ventricular remodeling parameter levels, and so on were compared between two groups of patients before and after treatment.Results: Before treatment, serum contents of neuroendocrine molecules and ventricular remodeling-related indexes as well as Doppler ultrasonic ventricular remodeling parameter levels were not statistically different between two groups of patients. After treatment, serum neuroendocrine molecules NT-proBNP, ANP, AngⅡ, ALD and NE contents of observation group were lower than those of control group, serum ventricular remodeling indexes TGF-β1, NF-κB, CysC and FGF23 contents were lower than those of control group, and ultrasonic ventricular remodeling parameters LVMI, LVRI, RVEDV and RVESV levels were lower than those of control group.Conclusion: Adjuvant Danhong injection therapy helps optimize the neuroendocrine molecule contents and inhibit the ventricular remodeling process in patients with ischemic cardiomyopathy heart failure.

Ferroelectric artificial synapse for neuromorphic computing and flexible applications

Research of artificial synapses is increasing in popularity with the development of bioelectronics and the appearance of wearable devices.Because the high-temperature treatment process of inorganic materials is not compatible with flexible substrates,organic ferroelectric materials that are easier to process have emerged as alternatives.An organic synaptic device based on P(VDF-TrFE)was prepared in this study.The device showed reliable P/E endurance over 104 cycles and a data storage retention capability at 80℃ over 104 s.Simultaneously,it possessed excellent synaptic functions,including short-term/long-term synaptic plasticity and spike-timing-dependent plasticity.In addition,the ferroelectric performance of the device remained stable even under bending(7 mm bending radius)or after 500 bending cycles.This work shows that low-temperature processed organic ferroelectric materials can provide new ideas for the future development of wearable electronics and flexible artificial synapses.

Floating-gate photosensitive synaptic transistors with tunable functions for neuromorphic computing

Synaptic devices that merge memory and processing functions into one unit have broad application potentials in neuromorphic computing, soft robots, and humanmachine interfaces. However, most previously reported synaptic devices exhibit fixed performance once been fabricated,which limits their application in diverse scenarios. Here, we report floating-gate photosensitive synaptic transistors with charge-trapping perovskite quantum dots(PQDs) and atomic layer deposited(ALD) Al_(2)O_(3) tunneling layers, which exhibit typical synaptic behaviors including excitatory postsynaptic current(EPSC), pair-pulse facilitation and dynamic filtering characteristics under both electrical or optical signal stimulation. Further, the combination of the high-quality Al2O3 tuning layer and highly photosensitive PQDs charge-trapping layer provides the devices with extensively tunable synaptic performance under optical and electrical co-modulation. Applying light during electrical modulation can significantly improve both the synaptic weight changes and the nonlinearity of weight updates, while the memory effect under light modulation can be obviously adjusted by the gate voltage.The pattern learning and forgetting processes for "0" and "1"with different synaptic weights and memory times are further demonstrated in the device array. Overall, this work provides synaptic devices with tunable functions for building complex and robust artificial neural networks.

Spectrum projection with a bandgap-gradient perovskite cell for colour perception

Optoelectronic devices for light or spectral signal detection are desired for use in a wide range of applications,including sensing,imaging,optical communications,and in situ characterization.However,existing photodetectors indicate only light intensities,whereas multiphotosensor spectrometers require at least a chip-level assembly and can generate redundant signals for applications that do not need detailed spectral information.Inspired by human visual and psychological light perceptions,the compression of spectral information into representative intensities and colours may simplify spectrum processing at the device level.Here,we propose a concept of spectrum projection using a bandgap-gradient semiconductor cell for intensity and colour perception.Bandgap-gradient perovskites,prepared by a halide-exchanging method via dipping in a solution,are developed as the photoactive layer of the cell.The fabricated cell produces two output signals:one shows linear responses to both photon energy and flux,while the other depends on only photon flux.Thus,by combining the two signals,the single device can project the monochromatic and broadband spectra into the total photon fluxes and average photon energies(i.e.,intensities and hues),which are in good agreement with those obtained from a commercial photodetector and spectrometer.Under changing illumination in real time,the prepared device can instantaneously provide intensity and hue results.In addition,the flexibility and chemical/bio-sensing of the device via colour comparison are demonstrated.Therefore,this work shows a human visual-like method of spectrum projection and colour perception based on a single device,providing a paradigm for high-efficiency spectrum-processing applications.

Temperature-induced resistance transition behaviors of melamine sponge composites wrapped with different graphene oxide derivatives

Temperature-re s ponsive resistance transition behaviors of the melamine sponges wrapped with different graphene oxide derivatives(i.e.nanoribbon,wide-ribbon and sheet)were investigated.Melamine sponge composites coated by three types of GO derivatives were prepared by a simple dip-coating approach.All these composites show good mechanical flexibility and reliability(almost unchanged compressive stress at 70%strain after 100 cycles),high hydrophobicity(water contact angle>120°),excellent flame resistance(self-extinguishing)and structural stability even after burning,which was used to construct the resistance-based fire alarm/warning sensor.Notably,the different resistance response behaviors of such sensors are strongly dependent on the GO size and network formed on the MF skeleton surface.Typically,at a fixed high temperature of~350℃,the three fire alarm sensors show different response time(to trigger the alarm light)of 6.3,8.4 and 11.1 s for nanoribbon,wide-ribbon and sheet at the same concentration,respectively.The structural observation and chemical analysis demonstrated that the discrepancy of temperature-responsive resistance transition behaviors of various GO derivatives was strongly determined by their different thermal reduction degrees during the high-tempe rature or flame treating process.This work offers a design and development for construction of smart fire alarm device for potential fire prevention and safety applications.

Synthesis,Characterization and Phase Behaviors of Polypeptides Bearing Biphenyl Mesogens and Oligo-Ethylene-Glycol Tails

A series ofpolypeptides bearing biphenyl mesogenic side-chains and oligo-ethylene-glycol （OEG） tails （PPLGn-g- BPOEGm, n = 26 and 63, m = 2, 3, and 7） has been synthesized via a 1,3-dipolar cycloaddition with quantitative grafting density. FTIR results revealed that the polypeptides adopted highly stable a-helix in the temperature range of 25-200 ℃. DSC, POM and WAXS analysis revealed that PPLGn-g-BPOEGm （m ≤ 3） samples with short OEG tail length showed two main phase transitions including crystal to liquid crystalline （smectie C, SmC） phase transition and the melting transition of crystalline E-phase, while PPLG,-g-BPOEG7 with longer OEG tail length （m = 7） exhibited the melting transitions without the formation of liquid crystalline phase.

Structural Restoration of the Medial Collateral Ligament Using Cubital Tunnel Retinaculum in Stiff Elbow Instability

To the Editor： lnstable elbow results from overuse and trauma. It brings pain and weakness to patients.HI There are three major considerations in treating this disease： central bone stability, lateral ligament stability, and medial ligament stability. The medial ligament includes the anterior, posterior, and transverse bundles.

General Decay for a Thermoelastic Problem of a Microbeam with Gurtin-Pipkin Thermal Law

In this paper,we study the well-posedness and the asymptotic stability of a one-dimensional thermoelastic microbeam system,where the heat conduction is given by Gurtin-Pipkin thermal law.We first establish the well-posedness of the system by using the semigroup arguments and Lumer-Phillips theorem.We then obtain an explicit and general formula for the energy decay rates through perturbed energy method and some properties of the convex functions.