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Association of plant-based diets with the risk of upper gastrointestinal tract cancers:A systematic review and meta-analysis
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作者 Shan-Rui Ma Yue-Ying Zhang +2 位作者 Zhi-Yuan Fan Fei-Fan He wen-qiang wei 《Journal of Nutritional Oncology》 2023年第4期183-195,共13页
Background:Diets rich in red or processed meat have been linked to an increased risk of cancers within the digestive system.It has been suggested that a plant-based diet may have protective effects against digestive s... Background:Diets rich in red or processed meat have been linked to an increased risk of cancers within the digestive system.It has been suggested that a plant-based diet may have protective effects against digestive system cancers.This study aimed to determine the association between plant-based diets and upper gastrointestinal tract cancers(UGTC).Methods:We conducted a systematic review and meta-analysis of observational studies.We searched the PubMed,Medline,Embase,and Web of Science databases for articles published up to September 30,2023.We pooled the risk ratios(RR)with the corresponding 95%confi-dence intervals(CI)using fixed or random-effects models.Results:Our meta-analysis included 16 studies(30 results).The data revealed a strong inverse association between a high intake of plant-based diets and UGTC(RR=0.60,95%CI=0.49-0.72),specifically gastric cancer(GC,RR=0.53,95%CI=0.42-0.67)and esophageal can-cer(EC,RR=0.63,95%CI=0.42-0.96).This relationship was not significant for gastric cardia cancer(GCA)or esophagogastric junctional cancer(EGJC,RR=0.76,95%CI=0.47-1.22).A subgroup analysis showed the association was significant in studies from Asia and Europe,as well as in studies utilizing indices such as a vegetarian diet,Mediterranean diet,the plant-based diet index,and principal component analy-sis(PCA)dietary patterns.There was no indication of publication bias among the analyzed studies.Conclusions:This meta-analysis highlights the potential health benefits of plant-based diets in preventing UGTC,particularly regarding esophageal squamous cell carcinoma(ESCC)and GC.Nevertheless,additional research is required to validate these results and explore the un-derlying mechanisms. 展开更多
关键词 upper gastrointestinal tract cancers plant-based diets META-ANALYSIS
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Comparative epidemiology of gastric cancer between Japan and China 被引量:64
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作者 Yingsong Lin Junko Ueda +4 位作者 Shogo Kikuchi Yukari Totsuka wen-qiang wei You-Lin Qiao Manami Inoue 《World Journal of Gastroenterology》 SCIE CAS CSCD 2011年第39期4421-4428,共8页
AIM:To clarify the similarities and differences in gastric cancer epidemiology between Japan and China.METHODS:A comprehensive literature search of the PubMed database was performed.The relevant literature published i... AIM:To clarify the similarities and differences in gastric cancer epidemiology between Japan and China.METHODS:A comprehensive literature search of the PubMed database was performed.The relevant literature published in China was also been cited.Data on incidence and mortality rates in 2008 were obtained from the Cancer Mondial database,published by International Agency for Research on Cancer at http://www-dep.iarc.fr/.RESULTS:Gastric cancer remains a significant publichealth burden in both Japan and China.The prevalence of Helicobacter pylori(H.pylori)colonization is high in the adult populations of both countries.Accumulating evidence from intervention studies in both countries has shown the effectiveness of H.pylori eradication in reduc-ing gastric cancer incidence.There are differences,however,in many aspects of gastric cancer,including patterns of incidence and mortality,trends in the prevalence of H.pylori infection,H.pylori strains,the magnitude of risk of gastric cancer related to H.pylori infection,and associations with dietary habits.Compared with China,Japan has seen a more rapid decline in H.pylori infection among adolescents.While Japanese cohort studies have dominated the literature concerning the associations between gastric cancer and dietary habits,numerous case-control studies in China suggest a positive association between a high intake of preserved fish and vegetables and gastric cancer risk.There is a need for a multidisciplinary research approach to understand the interactions between various strains of H.pylori,host factors,and other lifestyle and environmental factors in gastric carcinogenesis in both countries.CONCLUSION:The shared high incidence of gastric cancer and high prevalence of H.pylori,as well as differences in many aspects of gastric cancer,provide an excellent opportunity to establish Sino-Japanese collaborations. 展开更多
关键词 Gastric cancer Risk factor Helicobacter pylori EPIDEMIOLOGY
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Cost-benefit analysis of esophageal cancer endoscopic screening in high-risk areas of China 被引量:33
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作者 Juan Yang wen-qiang wei +3 位作者 Jin Niu Zhi-Cai Liu Chun-Xia Yang You-Lin Qiao 《World Journal of Gastroenterology》 SCIE CAS CSCD 2012年第20期2493-2501,共9页
AIM:To estimate the cost-benefit of endoscopic screening strategies of esophageal cancer(EC)in high-risk areas of China. METHODS:Markov model-based analyses were conducted to compare the net present values(NPVs)and th... AIM:To estimate the cost-benefit of endoscopic screening strategies of esophageal cancer(EC)in high-risk areas of China. METHODS:Markov model-based analyses were conducted to compare the net present values(NPVs)and the benefit-cost ratios(BCRs)of 12 EC endoscopic screening strategies.Strategies varied according to the targeted screening age,screening frequencies,and follow-up intervals.Model parameters were collected from population-based studies in China,published literatures,and surveillance data. RESULTS:Compared with non-screening outcomes,all strategies with hypothetical 100 000 subjects saved life years.Among five dominant strategies determined by the incremental cost-effectiveness analysis,screening once at age 50 years incurred the lowest NPV(international dollar-I$55 million)and BCR(2.52).Screening six times between 40-70 years at a 5-year interval[i.e., six times(40)f-strategy]yielded the highest NPV(I$99 million)and BCR(3.06).Compared with six times(40)fstrategy,screening thrice between 40-70 years at a 10-year interval resulted in relatively lower NPV,but the same BCR. CONCLUSION:EC endoscopic screening is cost-beneficial in high-risk areas of China.Policy-makers should consider the cost-benefit,population acceptance,and local economic status when choosing suitable screening strategies. 展开更多
关键词 Cost-benefit analysis Esophageal cancer ENDOSCOPY SCREENING High-risk area
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Cost-benefit analysis of screening for esophageal and gastric cardiac cancer 被引量:15
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作者 wen-qiang wei Chun-Xia Yang +4 位作者 Si-Han Lu Juan Yang Bian-Yun Li Shi-Yong Lian You-Lin Qiao 《Chinese Journal of Cancer》 SCIE CAS CSCD 北大核心 2011年第3期213-218,共6页
In 2005, a program named "Early Detection and Early Treatment of Esophageal and Cardiac Cancer" (EDETEC) was initiated in China. A total of 8279 residents aged 40-69 years old were recruited into the EDETEC ... In 2005, a program named "Early Detection and Early Treatment of Esophageal and Cardiac Cancer" (EDETEC) was initiated in China. A total of 8279 residents aged 40-69 years old were recruited into the EDETEC program in Linzhou of Henan Province between 2005 and 2008. Howerer, the cost-benefit of the EDETEC program is not very clear yet. We conducted herein a cost-benefit analysis of screening for esophageal and cardiac cancer. The assessed costs of the EDETEC program included screening costs for each subject, as well as direct and indirect treatment costs for esophageal and cardiac severe dysplasia and cancer detected by screening. The assessed benefits of this program included the saved treatment costs, both direct and indirect, on esophageal and cardiac cancer, as well as the value of prolonged life due to screening, as determined by the human capital approach. The results showed the screening cost of finding esophageal and cardiac severe dysplasia or cancer ranged from $2707 to $4512, and the total cost on screening and treatment was $13 115-$14 920. The cost benefit was $58 944-$155 110 (the saved treatment cost, $17 730, plus the value of prolonged life, $41 214-$137 380). The ratio of benefit-to-cost (BCR) was 3.95-11.83. Our results suggest that EDETEC has a high benefit-to-cost ratio in China and could be instituted into high risk areas of China. 展开更多
关键词 成本效益分析 筛选检测 食管癌 贲门癌 早期治疗 胃癌 人生价值 总费用
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Attributable Causes of Cancer in China:Fruit and Vegetable 被引量:5
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作者 Hui-juan Xiao Hao Liang +5 位作者 Jian-bing Wang Cheng-Yu Huang wen-qiang wei Mathieu Boniol You-lin Qiao Paolo Boffetta 《Chinese Journal of Cancer Research》 SCIE CAS CSCD 2011年第3期171-176,共6页
Objective:To provide an evidence-based and consistent assessment of the burden of cancer attributable to inadequate fruit and vegetable intake in China in 2005.Methods:The proportions of cancers attributable to low ... Objective:To provide an evidence-based and consistent assessment of the burden of cancer attributable to inadequate fruit and vegetable intake in China in 2005.Methods:The proportions of cancers attributable to low consumption of vegetable and fruit were calculated separately to estimate the burden of related cancers for the year 2005 in China.Data on the prevalence of exposure were derived from a Chinese nutrition and health survey.Data on relative risks were mainly derived from meta-analysis.Attributable fractions were calculated based on the counterfactual scenario which was a shift in the exposure distribution.Results:The total cancer burden attributable to inadequate consumption of fruit was up to 233,000 deaths (13.0% of all cancers) and 300,000 cases (11.6% of all cancers) in 2005.Increasing consumption of vegetable to the highest quintile could avoid total cancer deaths and cases by 3.6% (64,000 persons) and 3.4% (88,000 persons).The contributions to cancer burden were higher in rural areas than in urban areas.They have greater influence on men than on women.The largest proportions of cancer burden attributable to low fruit and vegetable intake were for oral and pharyngeal cancers.Conclusion:This study showed that inadequate intake of fruit and vegetable makes a significant contribution to the cancer burden.Increasing consumption of fruit and vegetable could prevent many cancer deaths and save many lives.Promoting the consumption of fruit and vegetable is an important component in diet-based strategies for preventing cancer. 展开更多
关键词 FRUIT VEGETABLE CANCER Population attributable fraction China
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关节镜下微创治疗18例胫骨平台骨折合并前交叉韧带胫骨止点撕脱骨折的疗效观察 被引量:11
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作者 魏文强 顾峥嵘 +5 位作者 曹烈虎 方国正 梁志民 子树明 季佳庆 王雄 《中国内镜杂志》 2021年第5期84-88,共5页
目的探讨关节镜下微创治疗胫骨平台骨折合并前交叉韧带(ACL)胫骨止点撕脱骨折的手术效果。方法选择2016年7月-2019年7月上海市宝山区罗店医院骨科和锦州医科大学附属第三医院骨二科收治的18例胫骨平台骨折合并ACL胫骨止点撕脱骨折的患... 目的探讨关节镜下微创治疗胫骨平台骨折合并前交叉韧带(ACL)胫骨止点撕脱骨折的手术效果。方法选择2016年7月-2019年7月上海市宝山区罗店医院骨科和锦州医科大学附属第三医院骨二科收治的18例胫骨平台骨折合并ACL胫骨止点撕脱骨折的患者。利用关节镜进行关节腔检查、处理合并症、复位骨折及微创内固定,采用膝关节功能HSS评分分别在术后3、6和12个月对患者进行随访,评估患肢膝关节的功能。结果所有患者术后切口均无感染,愈合良好,随访时间3~12个月,平均6个月。术后12个月膝关节功能为:优6例(33.3%)、良10例(55.6%)、可2例(11.1%)。结论关节镜结合微创内固定治疗胫骨平台骨折合并ACL胫骨止点撕脱骨折,患者膝关节功能恢复良好。 展开更多
关键词 胫骨平台骨折 关节镜 微创内固定 前交叉韧带
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Evaluation of routine biopsies in endoscopic screening for esophagogastric junction cancer 被引量:2
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作者 Xin Niu wen-qiang wei +10 位作者 Chang-Qing Hao Guo-Hui Song Jun Li Zhao-Lai Hua Yong-wei Li Jun Chang Xin-Zheng Wang De-Li Zhao Guo-Qing Wang Evelyn Hsieh You-Lin Qiao 《World Journal of Gastroenterology》 SCIE CAS 2014年第17期5074-5081,共8页
AIM: To explore whether routine biopsies at the high incidence spot of esophagogastric junction (EGJ) cancer are justified in endoscopic screening.
关键词 Esophagogastric junction cancer High incidence spot Screening ENDOSCOPY BIOPSY
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