期刊文献+
共找到36篇文章
< 1 2 >
每页显示 20 50 100
Establishment and Application of Identification Methods for Resistance to Sugarcane White Leaf Disease(SCWL)
1
作者 wenfeng li Rongyue ZHANG +4 位作者 Xiaoyan WANG Hongli SHAN Jie li Yinhu li Yingkun HUANG 《Agricultural Biotechnology》 CAS 2023年第1期12-15,共4页
[Objectives]This study was conducted to establish simple, efficient, stable, standardized and practical identification methods for sugarcane resistance to white leaf disease(SCWL), and promote the breeding for sugarca... [Objectives]This study was conducted to establish simple, efficient, stable, standardized and practical identification methods for sugarcane resistance to white leaf disease(SCWL), and promote the breeding for sugarcane resistance to SCWL. [Methods]The identification technology of sugarcane resistance to SCWL was systematically studied and explored from the aspects of sugarcane material treatment and planting, inoculation liquid preparation, inoculation method, disease investigation, grading standard formulation, etc., and two sets of simple, efficient, stable, standardized and practical accurate identification methods for sugarcane resistance to SCWL were created for the first time, namely, the seed cane coating inoculation method and the stem-cutting inoculation method at the growth stage. The seed cane coating inoculation method includes the steps of directly screening SCWL phytoplasma, extracting juice from cane and adding 10 times of sterile water to prepare an inoculation liquid, spraying seed cane on plastic film to keep moisture, planting the inoculated materials in barrels in an insect-proof greenhouse for cultivation, investigating the incidence rate 30 d after inoculation, and evaluating the disease resistance according to the 1-5 level standard. The method of stem-cutting inoculation includes the steps of directly screening sugarcane stems carrying SCWL phytoplasma and adding 10 times of sterile water to prepare an inoculation liquid, cultivating the identification materials in an insect-proof greenhouse, dropping 100 μl of the inoculation liquid into each root incision with a pipette gun at the age of 6 months, investigating the incidence rate 20 d after planting, and evaluating the disease resistance according to the 1-5 level standard. [Results] The two methods are similar to the natural transmission method. After inoculation, SCML occurred significantly, with high sensitivity and good reproducibility. The results of resistance identification were consistent with those of natural disease in the field. Through the two inoculation methods and field natural disease investigation, the resistance of 10 main cultivars to SCML was identified, which was true and reliable. [Conclusions] This study can provide standard varieties for identification of SCML resistance in the future. 展开更多
关键词 Sugarcane white leaf disease Inoculation technology Seed cane-spraying inoculation Stem-cutting inoculation method Identification of disease resistance
下载PDF
Observation on the Application Effect of Targeted Infusion Safety Nursing in Inpatients with Cancer
2
作者 Xue Jin wenfeng li 《Journal of Clinical and Nursing Research》 2023年第4期38-44,共7页
Objective:To study the clinical effect of targeted infusion safety nursing during infusion of inpatients with cancer.Methods:From January 1,2020,to January 1,2023,a total of 6,614 infusion patients were treated in The... Objective:To study the clinical effect of targeted infusion safety nursing during infusion of inpatients with cancer.Methods:From January 1,2020,to January 1,2023,a total of 6,614 infusion patients were treated in The First Affiliated Hospital of Wenzhou Medical University,and 300 inpatients with cancer were selected as the research objects and randomly divided into the observation group and the control group,with 150 patients in each group.The control group received routine infusion nursing,and the observation group received targeted infusion safety nursing.The targeted infusion safety nursing was judged by comparing the nursing quality assessment,incidence of adverse events,patient compliance,and patients’mastery of infusion knowledge between the two groups.clinical effect.Results:After the targeted infusion safety nursing was given to the patients in the observation group,the patients in this group recognized the nursing quality,and the statistical score was higher than that in the control group;the incidence of adverse events in the observation group was lower than that in the control group.The compliance of the observation group was higher than that of the control group.The mastery of health knowledge in the observation group was also higher than that in the control group and the difference was statistically significant(P<0.02).Conclusion:After implementing targeted infusion safety nursing for inpatients with cancer,it can effectively prevent the occurrence of adverse events,improve patient compliance,and increase the mastery of relevant knowledge of patients. 展开更多
关键词 Tumor patients Infusion nursing Targeted safety nursing Adverse events
下载PDF
Hydromechanical characterization of gas transport amidst uncertainty for underground nuclear explosion detection 被引量:1
3
作者 wenfeng li Chelsea W.Neil +3 位作者 J William Carey Meng Meng Luke P.Frash Philip H.Stauffer 《Journal of Rock Mechanics and Geotechnical Engineering》 SCIE CSCD 2024年第6期2019-2032,共14页
Given the challenge of definitively discriminating between chemical and nuclear explosions using seismic methods alone,surface detection of signature noble gas radioisotopes is considered a positive identification of ... Given the challenge of definitively discriminating between chemical and nuclear explosions using seismic methods alone,surface detection of signature noble gas radioisotopes is considered a positive identification of underground nuclear explosions(UNEs).However,the migration of signature radionuclide gases between the nuclear cavity and surface is not well understood because complex processes are involved,including the generation of complex fracture networks,reactivation of natural fractures and faults,and thermo-hydro-mechanical-chemical(THMC)coupling of radionuclide gas transport in the subsurface.In this study,we provide an experimental investigation of hydro-mechanical(HM)coupling among gas flow,stress states,rock deformation,and rock damage using a unique multi-physics triaxial direct shear rock testing system.The testing system also features redundant gas pressure and flow rate measurements,well suited for parameter uncertainty quantification.Using porous tuff and tight granite samples that are relevant to historic UNE tests,we measured the Biot effective stress coefficient,rock matrix gas permeability,and fracture gas permeability at a range of pore pressure and stress conditions.The Biot effective stress coefficient varies from 0.69 to 1 for the tuff,whose porosity averages 35.3%±0.7%,while this coefficient varies from 0.51 to 0.78 for the tight granite(porosity<1%,perhaps an underestimate).Matrix gas permeability is strongly correlated to effective stress for the granite,but not for the porous tuff.Our experiments reveal the following key engineering implications on transport of radionuclide gases post a UNE event:(1)The porous tuff shows apparent fracture dilation or compression upon stress changes,which does not necessarily change the gas permeability;(2)The granite fracture permeability shows strong stress sensitivity and is positively related to shear displacement;and(3)Hydromechanical coupling among stress states,rock damage,and gas flow appears to be stronger in tight granite than in porous tuff. 展开更多
关键词 Underground nuclear explosion uncertainty quantification Radionuclide transport Biot effective stress coefficient Fracture permeability Matrix permeability
下载PDF
Effect of stress-dependent microannulus aperture on well leakage 被引量:1
4
作者 Meng Meng Luke P.Frash +3 位作者 J.William Carey Mohamed Mehana wenfeng li Bailian Chen 《Journal of Rock Mechanics and Geotechnical Engineering》 SCIE CSCD 2024年第6期1967-1976,共10页
Debonding at the cement-casing interface is recognized as a principal failure mechanism leading to CO_(2) leakage in wells.This detachment gives rise to a microannulus,which notably possesses greater permeability than... Debonding at the cement-casing interface is recognized as a principal failure mechanism leading to CO_(2) leakage in wells.This detachment gives rise to a microannulus,which notably possesses greater permeability than undamaged cement,undermining its sealing efficacy.Conventionally,the permeability of the microannulus is regarded as a uniform value throughout the well.However,fundamentally,a microannulus is one type of fracture,and its gap or aperture size is affected by the effective stress.In this work,we developed a unique experimental apparatus.This equipment facilitates the curing of cement inside a steel casing,the formation of a microannulus between the casing and the cement,and the investigation of the fluid flow dynamics along the microannulus under laboratory-replicated in situ conditions.The microannulus was formed by injecting fluid from one end of the setup,and receiving similar amount of fluid on the other end signified the development of the leakage channel.Additionally,strain gauges affixed to the casing’s external surface yielded key information on the microannulus’s opening and closure.We observed a noticeable decline in microannulus hydraulic aperture(or permeability)in relation to effective stress and an exponential equation fits their relationship.Our findings also indicate a distinct behavior when comparing liquid CO_(2) with water.Specifically,it is easier for liquid CO_(2) to create the microannulus.However,the hydraulic aperture range for this microannulus(0.7-6 mm)is considerably smaller than that created by water flow(2-17 mm).Finally,we integrated the stressdependent microannulus aperture size into the combined analysis of well mechanical integrity and well leakage.The outcomes consistently demonstrated that when factoring in the stress-dependent aperture sizes,the leakage rates are 3e5 times compared to a fixed aperture model.The traditional assumption of a constant aperture significantly underestimates fluid leakage risks. 展开更多
关键词 Microannulus Leakage assessment Aperture size Triaxial experiment Carbon sequestration
下载PDF
A Methodology for Reliability of WSN Based on Software Defined Network in Adaptive Industrial Environment 被引量:7
5
作者 Ying Duan wenfeng li +2 位作者 Xiuwen Fu Yun Luo lin Yang 《IEEE/CAA Journal of Automatica Sinica》 SCIE EI CSCD 2018年第1期74-82,共9页
As communication technology and smart manufacturing have developed, the industrial internet of things(IIo T)has gained considerable attention from academia and industry.Wireless sensor networks(WSNs) have many advanta... As communication technology and smart manufacturing have developed, the industrial internet of things(IIo T)has gained considerable attention from academia and industry.Wireless sensor networks(WSNs) have many advantages with broad applications in many areas including environmental monitoring, which makes it a very important part of IIo T. However,energy depletion and hardware malfunctions can lead to node failures in WSNs. The industrial environment can also impact the wireless channel transmission, leading to network reliability problems, even with tightly coupled control and data planes in traditional networks, which obviously also enhances network management cost and complexity. In this paper, we introduce a new software defined network(SDN), and modify this network to propose a framework called the improved software defined wireless sensor network(improved SD-WSN). This proposed framework can address the following issues. 1) For a large scale heterogeneous network, it solves the problem of network management and smooth merging of a WSN into IIo T. 2) The network coverage problem is solved which improves the network reliability. 3) The framework addresses node failure due to various problems, particularly related to energy consumption.Therefore, it is necessary to improve the reliability of wireless sensor networks, by developing certain schemes to reduce energy consumption and the delay time of network nodes under IIo T conditions. Experiments have shown that the improved approach significantly reduces the energy consumption of nodes and the delay time, thus improving the reliability of WSN. 展开更多
关键词 Industrial internet of things(IIo T) RELIABILITY software defined network(SDN) wireless sensor network(WSN)
下载PDF
A Publish-Subscribe Networking Architecture for Future Manned Deep Space Exploration 被引量:2
6
作者 liuting Gu Lai Yu +1 位作者 wenfeng li Kanglian Zhao 《China Communications》 SCIE CSCD 2020年第7期38-51,共14页
With the further development of the Deep Space Networking(DSN),more and more satellites and space probes will be put into space which makes the DSN more diverse and complex.We argued that Information Centric Networkin... With the further development of the Deep Space Networking(DSN),more and more satellites and space probes will be put into space which makes the DSN more diverse and complex.We argued that Information Centric Networking(ICN)may be a suitable architecture for the DSN.In this paper,a publish-subscribe networking architecture based on ICN is proposed for future manned deep space exploration network.It adopts the publish-subscribe mechanism and decouples the control plane and data plane logically.In the proposed architecture,the improvement of routing is made to tolerant the long propagation delay and frequent link disruptions of deep space.And the multi-source transmission is considered to deal with the large amount of data in the future manned deep space exploration network.We evaluated the feasibility of the architecture and the performance of the protocol stack,the improved routing mechanism and the multi-source transmission.The results indicate that Publish-Subscribe Networking(PSN)can cope with the harsh transmission conditions,and the multi-source transmission can reduce the delivery time of data.It enables the network to allocate and share resources more efficiently and keeps the network well managed. 展开更多
关键词 DEEP NETWORKING PUBLISH
下载PDF
Spongy acetylenic carbon material prepared by ball milling CaC2 and chlorinated rubber—Its mercury adsorption and electrochemical property 被引量:1
7
作者 Xuebing Xu wenfeng li +3 位作者 Luyan Xia Yingzhou Lu Hong Meng Chunxi li 《Chinese Journal of Chemical Engineering》 SCIE EI CAS CSCD 2019年第8期1988-1995,共8页
Design and preparation of novel advanced carbon materials with unique architecture and functional groups is of great significance.Herein,a spongy acetylenic carbon material(SACM) was prepared through mechanochemical r... Design and preparation of novel advanced carbon materials with unique architecture and functional groups is of great significance.Herein,a spongy acetylenic carbon material(SACM) was prepared through mechanochemical reaction of CaC2 and chlorinated rubber in a planetary ball mill at ambient temperature.Its composition and structure were characterized,and its electrochemical properties and adsorption performance for Hg^2+ were studied.The SACM is composed of submicron spongy aggregates with high carbon content(81.8%) and specific area(503.9 m^2·g^-1),rich porosity and acetylenic groups.The SACM exhibits excellent adsorption for Hg2+with saturated adsorption amount being 157.1 mg·g^-1,which is superior to conventional carbon materials.Further,it exhibits good electrochemical performance with low equivalent series resistance(0.50 Ω),excellent cycling stability and ideal double layer capacitive behavior.This paper provides a novel and universal synthesis method of spongy carbon materials,and better results can be expected through tuning the pore structure,graphitization degree,and heteroatoms of the target carbon materials. 展开更多
关键词 Acetylenic carbon material CALCIUM CARBIDE MECHANOCHEMICAL reaction HEAVY metal ADSORPTION
下载PDF
Geostatistical Analysis of Spatial Distribution and Dynamics of Dead Heart of Sugarcane Seedlings Caused by Borer 被引量:2
8
作者 Zhiming LUO Jiong YIN +4 位作者 wenfeng li Rongyue ZHANG Hongli SHAN Xiaoyan WANG Yingkun HUANG 《Agricultural Science & Technology》 CAS 2017年第4期637-641,共5页
Dead heart of sugarcane is an important symptom caused by borer attack. In the present study, the spatial distribution and dynamics of dead heart of sugarcane in the field were investigated based on geostatistical ana... Dead heart of sugarcane is an important symptom caused by borer attack. In the present study, the spatial distribution and dynamics of dead heart of sugarcane in the field were investigated based on geostatistical analysis, and semivariograms were computed in four separate directions(0°, 45°, 90° and 135°) and fitted with various theoretical models to determine the best fitted one. The Ordinary Kriging was used to interpolate spatial data. The results revealed that the density of dead hearts of sugarcane increased in a single-peak pattern, and the degree of spatial aggregation and random variation both decreased with the increase in the density of dead heart. In addition, dead heart of sugarcane caused by borer exhibited spatial aggregation.With the increase in the density of dead heart, the degree of spatial aggregation decreased, while the correlation increased. Kriging interpolation indicated that the correlation between the spatial patches was weak in early seedling stage, and became strong in middle and late seedling stage. 展开更多
关键词 SUGARCANE Dead heart Geostatistics Spatial distribution and dynamics
下载PDF
A novel spherical-headed fascial dilator is feasible for second-stage ultrasound guided percutaneous nephrolithotomy:A pilot study
9
作者 Yiwei Wang liheng Gao +6 位作者 Mingxi Xu wenfeng li Yuanshen Mao Fujun Wang Lu Wang Jun Da Zhong Wang 《Asian Journal of Urology》 CSCD 2021年第4期424-429,共6页
Objective:In second-stage percutaneous nephrolithotomy(PCNL),because the hydronephrosis has been decompressed,the dilated renal pelvis has resolved and the space is small.Consequently,introduction of the tip of the Am... Objective:In second-stage percutaneous nephrolithotomy(PCNL),because the hydronephrosis has been decompressed,the dilated renal pelvis has resolved and the space is small.Consequently,introduction of the tip of the Amplatz dilator can cause injury to the opposite side of the renal-pelvic mucosa.In this study,we report the experimental and initial clinical performance of a spherical-headed fascial dilator developed specifically for second-stage PCNL.Methods:The novel spherical-headed dilator was compared with existing tapered-headed dilators in configuration and in puncture resistance utilizing a static puncture test.Subsequently,a pilot clinical study was conducted during which patients scheduled to undergo second-stage PCNL from June 2019 to October 2019 in our center were enrolled.A typical ultrasound guided PCNL procedure was performed with the exception that the new spherical-headed fascial dilator was substituted for a tapered-headed one.Results:Experimentally,stab resistance against polyethylene film was significantly increased using the novel spherical-headed dilator compared to the traditional tapered-headed dilators(p<0.005).In the clinical study,the novel dilators were successfully introduced into the renal pelvis and passed down the collecting system in all eight second-stage PCNL cases.There were no cases of renal pelvic perforation or brisk hemorrhage nor need for transfusion. 展开更多
关键词 Percutaneous nephrolithotomy Fascial dilator Ultrasound guidance Kidney stones without hydronephrosis
下载PDF
Integration and Application of Comprehensive Prevention and Control Technology for Sugarcane Borers in Low Latitude Plateau of China
10
作者 wenfeng li Rongyue ZHANG +6 位作者 Jiong YIN Xiaoyan WANG Hongli SHAN Jie li Zhiming LUO Xiaoyan CANG Yingkun HUANG 《Agricultural Biotechnology》 CAS 2019年第4期72-77,80,共7页
Aimed at the difficult problem of prevention and control of disastrous sugarcane borers in low latitude plateau of China,this research systematically overcame the bottleneck of comprehensive prevention and control of ... Aimed at the difficult problem of prevention and control of disastrous sugarcane borers in low latitude plateau of China,this research systematically overcame the bottleneck of comprehensive prevention and control of sugarcane bores after 10 years of collaborative research,and formed a number of core product technologies,which promoted the green and high-quality development of the sugarcane industry and achieved the following innovative results.In this study,the species,population structure and damage characteristics of disastrous sugarcane borers in low latitude plateau were clarified for the first time,which provided a scientific basis for the formulation of technology and application of comprehensive prevention and control.The monitoring technology system and early warning monitoring network were constructed for the monitoring of borer population in low latitude plateau sugarcane area,which realized the accurate monitoring of the population dynamics of sugarcane bores and provided technical support for comprehensive prevention and control.The flight spraying technology by unmanned aerial vehicle(UAV)was developed for bores in the low latitude plateau cane area,and it has been successfully applied in a large area,thereby opening up a new way of light,simple and efficient for effective control of borers.The scale application of lamp trapping and sexual attracting to kill adult insects technology promoted the advancement of green control technology of bores.Integration was made to the comprehensive control techniques like UAV flight control,biological agents,physical and chemical inducement and control,and sexual attractant trapping in the low latitude plateau sugarcane area,and standardized technical regulations have been formulated,which significantly improved the overall prevention and control effect of large areas.The technologies for the comprehensive prevention and control of sugarcane borers have been popularized and applied in 8 major sugarcane producing states(cities)in low altitude plateau of Yunnan over the years,which has controlled the damage and showed remarkable control effect.In 2017-2018,the integrated control technology was popularized and applied to a total of 2.78×10^5 hm^2(1.33×10^4 hm^2 of UAV flight control)of area,which recovered a total of 3.666×10^6 t of sugarcane losses,increasing 4.69×10^5 t of sugar with the sales increase of 3.979 billion yuan,added profits of 1.251 billion yuan and the taxes increase of 188 million yuan.The research results show that the technology has high technical integration,strong practicability,high degree of transformation,significant economic,social and ecological benefits,which provide technical supports for the sustainable development,loss reduction and efficiency increase of the sugarcane industry in the low-latitude plateau sugarcane region,and make significant contributions to the economic development of ethnic minorities in the border-stricken areas and the increase of farmers income and poverty alleviation. 展开更多
关键词 Low LATITUDE PLATEAU SUGARCANE BORERS COMPREHENSIVE PREVENTION and control Application
下载PDF
Dominant Natural Enemies of Sugarcane Pests and Their Protection and Utilization in Yunnan
11
作者 Jie li wenfeng li +6 位作者 Rongyue ZHANG Hong li SHAN Jiong YIN Zhiming LUO Xiaoyan WANG Xiaoyan CANG Yingkun HUANG 《Agricultural Biotechnology》 CAS 2019年第6期52-56,共5页
This paper discussed and summarized the parasitic characters and the protection and utilization of 7 species of dominant natural enemies of sugarcane pests in Yunnan, China. Sugarcane pests are numerous and there are ... This paper discussed and summarized the parasitic characters and the protection and utilization of 7 species of dominant natural enemies of sugarcane pests in Yunnan, China. Sugarcane pests are numerous and there are rich natural enemy resources in Yunnan sugarcane areas. There are more than 283 species of natural enemies against sugarcane pests in Yunnan, among which the dominant natural enemies with protection and utilization value and research significance include Trichogramma, Apanteles flavipes(Cameron) and Sturmiopsis inferens Townsend parasitic on sugarcane borers, Synonycha grandis(Thunberg), Lemnia biplagiata(Swartz), Chilomenes sexmaculata(Fabricius) and Thiallela sp catching and feeding on Ceratovacuna lanigera Zehntner, and Euborellia pallipes Shiraki preying on Saccharicocus sacchari(Cocherell), Dysmicoccus bohinsis Kuw, Trochorhopalus humeralis Chevrolat and Diocalandra sp. There is also one fungal parasite, namely Beauveria bassiana, which is widely distributed in nature, and can parasitize in a variety of sugarcane pests including sugarcane borers, Exolontha serrulata(Gyllenhal), Alissonotum impressicolle Arrow, T. humeralis and Otidognathus rubriceps Chevrola. It has a natural parasitism rate generally around 10% and certain natural inhibition effect on sugarcane pests. Reasonably protecting and utilizing natural enemies and giving full play to the natural regulation of natural enemies on pests are of great significance for protecting the ecological environment, maintaining the ecological balance of sugarcane fields, improving the comprehensive management level of pests, and promoting the sustainable development of sugar industry. 展开更多
关键词 SUGARCANE PEST Dominant natural enemies Protection and utilization
下载PDF
Analysis of the effect of holmium laser flexible ureteroscopic intrapelvic drainage in the treatment of parapelvic renal cysts
12
作者 Yuanshen Mao wenfeng li +5 位作者 Jun Da Mingxi Xu Yiwei Wang Yufei Gu Weixin Pan Zhong Wang 《Asian Journal of Urology》 CSCD 2023年第2期172-176,共5页
Objective:To explore the efficacy,safety,and feasibility of holmium laser flexible ureteroscopic intrapelvic drainage in the treatment of parapelvic renal cysts.Methods:From September 2012 to February 2019,a total of ... Objective:To explore the efficacy,safety,and feasibility of holmium laser flexible ureteroscopic intrapelvic drainage in the treatment of parapelvic renal cysts.Methods:From September 2012 to February 2019,a total of 18 patients,aged from 28 to 62(meanstandard deviation[SD]:46.50±9.14)years,were diagnosed with parapelvic renal cysts and treated by holmium laser flexible ureteroscopic intrapelvic drainage.There were 10 males and eight females.All of the parapelvic renal cysts were unilateral,and two cases were complicated with pyelolithiasis.The diameters of the cysts ranged from 4.1 cm to 8.2 cm.Results:All the patients completed the operation successfully in one stage without conversion to open surgery;in two cases,it was difficult to find the cysts during the operation,and the localization was completed by B-ultrasound and percutaneous injection of methylene blue.The mean operative time was 33.89(SD:9.68;range:22-54)min,and the mean hospitalization time was 2.67(SD:0.91;range:2-5)days.Three months and 6 months of follow-up were performed after surgery.The cysts disappeared in 13(72%)cases,and the diameter of the cysts in five(28%)cases decreased by more than 50%.Conclusion:Holmium laser flexible ureteroscopic intrapelvic drainage in the treatment of parapelvic renal cysts is simple,safe,and effective,and can be used as the first choice for the treatment of parapelvic renal cysts. 展开更多
关键词 Flexible ureteroscopy Holmium laser Parapelvic renal cyst B-ULTRASOUND Intrapelvic drainage
下载PDF
The clinical antiprotozoal drug nitazoxanide and its metabolite tizoxanide extend Caenorhabditis elegans lifespan and healthspan
13
作者 wenfeng li Shuming Chen +5 位作者 Jing Lang Jing Luo Jiahui Chen liping Zhang Zhijie Sun Deli Dong 《Acta Pharmaceutica Sinica B》 SCIE CAS CSCD 2024年第7期3266-3280,共15页
The drugs extending healthspan in clinic have always been searched.Nitazoxanide is an FDA-approved clinical antiprotozoal drug.Nitazoxanide is rapidly metabolized to tizoxanide after absorption in vivo.Our previous st... The drugs extending healthspan in clinic have always been searched.Nitazoxanide is an FDA-approved clinical antiprotozoal drug.Nitazoxanide is rapidly metabolized to tizoxanide after absorption in vivo.Our previous studies find that nitazoxanide and its metabolite tizoxanide induce mild mitochondrial uncoupling and activate cellular AMPK,oral nitazoxanide protects against experimental hyperlipidemia,hepatic steatosis,and atherosclerosis.Here,we demonstrate that both nitazoxanide and tizoxanide extend the lifespan and healthspan of Caenorhabditis elegans through Akt/AMPK/sir 2.1/daf16 pathway.Additionally,both nitazoxanide and tizoxanide improve high glucose-induced shortening of C.elegans lifespan.Nitazoxanide has been a clinical drug with a good safety profile,we suggest that it is a novel anti-aging drug. 展开更多
关键词 NITAZOXANIDE Tizoxanide C.elegans Healthspan LIFESPAN AMPK Akt Mitochondrial uncoupling
原文传递
Expert consensus on the diagnosis and treatment of solid tumors with BRAF mutations
14
作者 Wenxian Wang Bin lian +133 位作者 Chunwei Xu Qian Wang Ziming li Nan Zheng Aijun liu Jinpu Yu Wenzhao Zhong Zhijie Wang Yongchang Zhang Jingjing liu Shirong Zhang Xiuyu Cai Anwen liu Wen li lili Mao Ping Zhan Hongbing liu Tangfeng Lv liyun Miao lingfeng Min Yu Chen Jingping Yuan Feng Wang Zhansheng Jiang Gen lin Long Huang Xingxiang Pu Rongbo lin Weifeng liu Chuangzhou Rao Dongqing Lv Zongyang Yu Xiaoyan li Chuanhao Tang Chengzhi Zhou Junping Zhang Junli Xue Hui Guo Qian Chu Rui Meng Xuewen liu Jingxun Wu Rui Zhang Jin Zhou Zhengfei Zhu Yongheng li Hong Qiu Fan Xia Yuanyuan Lu Xiaofeng Chen Jian Feng Rui Ge Enyong Dai Yu Han Weiwei Pan Fei Pang Xin Huang Meizhen Hu Qing Hao Kai Wang Fan Wu Binbin Song Bingwei Xu liping Wang Youcai Zhu li lin Yanru Xie Xinqing lin Jing Cai ling Xu Jisheng li Xiaodong Jiao Kainan li Jia Wei Huijing Feng lin Wang Yingying Du Wang Yao Xuefei Shi Xiaomin Niu Dongmei Yuan Yanwen Yao Jianhui Huang Yue Feng Yinbin Zhang Pingli Sun Hong Wang Mingxiang Ye Dong Wang Zhaofeng Wang Yue Hao Zhen Wang Bin Wan Donglai Lv Shengjie Yang Jin Kang Jiatao Zhang Chao Zhang wenfeng li Jianfei Fu lizhi Wu Shijie Lan Juanjuan Ou lin Shi Zhanqiang Zhai Yina Wang Bihui li Zhang Zhang Ke Wang Xuelei Ma Zhongwu li Zhefeng liu Nong Yang lin Wu Huijuan Wang Gu Jin Guansong Wang Jiandong Wang Hubing Shi Meiyu Fang Yong Fang Yuan li Xiaojia Wang Jing Chen Yiping Zhang Xixu Zhu Yi Shen Shenglin Ma Biyun Wang Yong Song Zhengbo Song wenfeng Fang Yuanzhi Lu Lu Si 《The Innovation》 EI 2024年第6期100-116,共17页
The BRAF gene is an important signaling molecule in human cells that is involved in the regulation of cell growth,differentiation,and survival.When the BRAF gene mutates,it can lead to abnormal activation of the signa... The BRAF gene is an important signaling molecule in human cells that is involved in the regulation of cell growth,differentiation,and survival.When the BRAF gene mutates,it can lead to abnormal activation of the signaling pathway,which promotes cell proliferation,inhibits cell apoptosis,and ultimately contributes to the occurrence and development of cancer.BRAF mutations are widely present in various cancers,including malignant melanoma,thyroid cancer,colorectal cancer,non-small cell lung cancer,and hairy cell leukemia,among others.BRAF is an important target for the treatment of various solid tumors,and targeted combination therapies,represented by BRAF inhibitors,have become one of the main treatment modalities for a variety of BRAF-mutation-positive solid tumors. 展开更多
关键词 BRAF DIAGNOSIS TREATMENT
原文传递
Sampled-Data Asynchronous Fuzzy Output Feedback Control for Active Suspension Systems in Restricted Frequency Domain 被引量:6
15
作者 wenfeng li Zhengchao Xie +2 位作者 Yucong Cao Pak Kin Wong Jing Zhao 《IEEE/CAA Journal of Automatica Sinica》 SCIE EI CSCD 2021年第5期1052-1066,共15页
This paper proposes a novel sampled-data asynchronous fuzzy output feedback control approach for active suspension systems in restricted frequency domain.In order to better investigate uncertain suspension dynamics,th... This paper proposes a novel sampled-data asynchronous fuzzy output feedback control approach for active suspension systems in restricted frequency domain.In order to better investigate uncertain suspension dynamics,the sampleddata Takagi-Sugeno(T-S)fuzzy half-car active suspension(HCAS)system is considered,which is further modelled as a continuous system with an input delay.Firstly,considering that the fuzzy system and the fuzzy controller cannot share the identical premises due to the existence of input delay,a reconstructed method is employed to synchronize the time scales of membership functions between the fuzzy controller and the fuzzy system.Secondly,since external disturbances often belong to a restricted frequency range,a finite frequency control criterion is presented for control synthesis to reduce conservatism.Thirdly,given a full information of state variables is hardly available in practical suspension systems,a two-stage method is proposed to calculate the static output feedback control gains.Moreover,an iterative algorithm is proposed to compute the optimum solution.Finally,numerical simulations verify the effectiveness of the proposed controllers. 展开更多
关键词 Active suspension asynchronous constraints output feedback restricted frequency domain sampled-data control Takagi-Sugeno(T-S)fuzzy
下载PDF
A Combining Call Admission Control and Power Control Scheme for D2D Communications Underlaying Cellular Networks 被引量:7
16
作者 Xujie li Wenna Zhang +1 位作者 Honglang Zhang wenfeng li 《China Communications》 SCIE CSCD 2016年第10期137-145,共9页
As device-to-device(D2D) communications usually reuses the resource of cellular networks, call admission control(CAC) and power control are crucial problems. However in most power control schemes, total data rates or ... As device-to-device(D2D) communications usually reuses the resource of cellular networks, call admission control(CAC) and power control are crucial problems. However in most power control schemes, total data rates or throughput are regarded as optimization criterion. In this paper, a combining call admission control(CAC) and power control scheme under guaranteeing QoS of every user equipment(UE) is proposed. First, a simple CAC scheme is introduced. Then based on the CAC scheme, a combining call admission control and power control scheme is proposed. Next, the performance of the proposed scheme is evaluated. Finally, maximum DUE pair number and average transmitting power is calculated. Simulation results show that D2 D communications with the proposed combining call admission control and power control scheme can effectively improve the maximum DUE pair number under the premise of meeting necessary QoS. 展开更多
关键词 device-to-device(D2D) call admission control power control cellular networks
下载PDF
Static-Output-Feedback Based Robust Fuzzy Wheelbase Preview Control for Uncertain Active Suspensions With Time Delay and Finite Frequency Constraint 被引量:2
17
作者 wenfeng li Zhengchao Xie +3 位作者 Jing Zhao Pak Kin Wong Hui Wang Xiaowei Wang 《IEEE/CAA Journal of Automatica Sinica》 SCIE EI CSCD 2021年第3期664-678,共15页
This paper proposes a static-output-feedback based robust fuzzy wheelbase preview control algorithm for uncertain active suspensions with time delay and finite frequency constraint.Firstly,a Takagi-Sugeno(T-S)fuzzy au... This paper proposes a static-output-feedback based robust fuzzy wheelbase preview control algorithm for uncertain active suspensions with time delay and finite frequency constraint.Firstly,a Takagi-Sugeno(T-S)fuzzy augmented model is established to formulate the half-car active suspension system with consideration of time delay,sprung mass variation and wheelbase preview information.Secondly,in view of the resonation between human’s organs and vertical vibrations in the frequency range of 4–8 Hz,a finite frequency control criterion in terms of H∞norm is developed to improve ride comfort.Meanwhile,other mechanical constraints are also considered and satisfied via generalized H2 norm.Thirdly,in order to maintain the feasibility of the controller despite of some state variables are not online-measured,a two stage approach is adopted to derive a static output feedback controller.Finally,numerical simulation results illustrate the excellent performance of the proposed controller. 展开更多
关键词 Active suspension finite frequency output feedback Takagi-Sugeno(T-S)fuzzy model time delay wheelbase preview
下载PDF
Occurrence and Epidemic Dynamics and Accurate Prevention and Control of Important Sugarcane Pests and Diseases in the Sugarcane Areas of Yunnan 被引量:2
18
作者 wenfeng li Rongyue ZHANG +6 位作者 Hongli SHAN Xiaoyan WANG Jiong YIN Zhiming LUO Jie li Xiaoyan CANG Yingkun HUANG 《Agricultural Biotechnology》 CAS 2018年第5期148-152,共5页
Based on investigation and research, according to the current actual production of sugarcane, the occurrence dynamics and outbreak causes of important pests and diseases that seriously affect sugarcane production were... Based on investigation and research, according to the current actual production of sugarcane, the occurrence dynamics and outbreak causes of important pests and diseases that seriously affect sugarcane production were summarized, and accurate and efficient green prevention and control technology was put forward according to the occurrence and damage characteristics of important pests and diseases, such as strengthening sugarcane introduction and quarantine, breeding and selecting varieties resistant to diseases and pests, promoting the use of detoxified healthy seedlings vigorously, applying lamp trapping technology on a large scale, scientifically guiding and promoting biological prevention and control technology, practically promoting the precise and efficient application of slow-release long- acting and low toxic pesticides, strengthening field management, spraying pesticides in time at the early stage of a disease, and doing a good job of monitoring and emergency prevention and control of sudden pests. 展开更多
关键词 Sugarcane areas of Yunnan SUGARCANE Pests and diseases Epidemic dynamics Accurate prevention and control
下载PDF
Unmanned Aerial Vehicle Control of Major Sugarcane Diseases and Pests in Low Latitude Plateau 被引量:1
19
作者 Xiaoyan WANG Rongyue ZHANG +8 位作者 Hongli SHAN Yuanhong FAN Hong XU Pizhong HUANG Zejuan li Tingying DUAN Ning KANG wenfeng li Yingkun HUANG 《Agricultural Biotechnology》 CAS 2019年第4期48-51,共4页
This research was aimed at the defects in traditional artificial spraying control method and the problems such as the difficulty in pesticides applying,labor shortage and low operating efficiency in the middle and lat... This research was aimed at the defects in traditional artificial spraying control method and the problems such as the difficulty in pesticides applying,labor shortage and low operating efficiency in the middle and late stage of sugarcane high stalk crops.The aerial pesticide application technology for sugarcane main diseases and pests was systematically developed and demonstrated from the aspects of aircraft type choice,selection of special pesticides and auxiliaries,integration of pesticides and equipment,field operation,technical specifications,and large-scale application organization mode.The UAV model and flight technical parameters suitable for the sugarcane planting area in low-latitude plateau were analyzed,and the optimal agent formulation combination and application technology of the UAV flight control were screened out,and the UAV flight control was applied to the major sugarcane pests and diseases control in the low-latitude plateau in large scale(UAV flight control was popularized and applied to 15 527 hm 2 in 2018).The research results provided mature whole-process technical support for the normalization of the application of the UVA flight control of major sugarcane pests and diseases.The UAV control technology for major sugarcane pests and diseases had the advantages of ultra-low pesticides applying dosage and high operating efficiency,and could effectively solve the problems such as the difficulty in pesticides applying,labor shortage and low operating efficiency in the middle late growth stage of high stalk crops.This technology successfully opened up a simple,efficient and new way for the effective control of major sugarcane pests and diseases,and practically accelerated the process of integrated control and prevention of sugarcane pests and diseases.In addition,this technology had an extremely significant effect on reducing the loss of sugarcane farmers and enterprises caused by the epidemic and outbreak of sugarcane pests and diseases,increasing sugarcane yield and sugar content.At the same time,this technology played an important role in realizing the whole-process precise control of sugarcane pests and diseases,improving the quality and increasing the efficiency of sugarcane,and guaranteeing the national sugar safety. 展开更多
关键词 Low LATITUDE PLATEAU SUGARCANE DISEASES and PESTS Unmanned AERIAL vehicle Prevention and control technology
下载PDF
Control Effect of Slow-release, Long-acting and Multi-functional New Pesticides on Sugarcane Borders and Woolly Aphids 被引量:1
20
作者 wenfeng li Rongyue ZHANG +6 位作者 Xiaoyan WANG Hongli SHAN Jiong YIN Yonglei MAO Chao FANG Zhiming LUO Yingkun HUANG 《Agricultural Biotechnology》 CAS 2018年第6期97-100,共4页
In order to select the long-acting,low toxic,low-risk and multi-functional new pesticides for the control of sugarcane borders and woolly aphids and precise and efficient application technology,the control effect of 1... In order to select the long-acting,low toxic,low-risk and multi-functional new pesticides for the control of sugarcane borders and woolly aphids and precise and efficient application technology,the control effect of 10% monosultap · thiamethoxam granular formulation and 1% Bt · clothianidin granular formulation on sugarcane borders and woolly aphids were studied.The results showed that 10% monosultap·thiamethoxam GR and 1% Bt·clothianidin GR had good control effects on sugarcane borders and woolly aphids.They were ideal slow-release,long-acting,low toxic and multi-functional new pesticides used to control sugarcane borders and woolly aphids.They could be used alternately with other pesticides to delay the emergence and development of pest resistance to pesticides.The best dosage of the two pesticides in the field was 45 kg/hm^2.They could be mixed with fertilizer( 1200-1800 kg/hm^2),scattered in sugarcane ditches or at the base of sugarcane plants,and covered with soil or film from January to July.The control effect on dead heart seedlings damaged by borers could be up to above 79.2%,and the control effect on sugarcane woolly aphids could reach more than 98.8%.In comparison with the control group,the actual yield and sugar content of sugarcane increased by above 41 555 kg/hm^2 and 6.5% respectively.The application of slow-release,long-acting,strong systemic and multi-functional new agents with fertilizer around roots is convenient,precise and efficient,labor-saving,time-saving and environmentally friendly,and is worthy of being widely applied in sugarcane areas. 展开更多
关键词 Slow-release and LONG-ACTING AGENTS PRECISE application of PESTICIDES SUGARCANE borders and woolly APHIDS Control effect
下载PDF
上一页 1 2 下一页 到第
使用帮助 返回顶部