This paper presents a discrete-time design of robust compositenonlinear controller to achieve fast and accurate set-pointtracking for motor servo systems subject to actuator saturationand disturbances.The basic idea h...This paper presents a discrete-time design of robust compositenonlinear controller to achieve fast and accurate set-pointtracking for motor servo systems subject to actuator saturationand disturbances.The basic idea here is to use a combination oflinear and nonlinear control,together with a disturbancerejection mechanism based on extended state observer.The linearcontrol part is designed to yield a fast response,and thenonlinear part serves to reduce the overshoot,while the extendedstate observer estimates simultaneously the state vector and theunknown disturbance for control and compensation.The closed-loopstability is analyzed using the Lyapunov theory.Practicalapplication in a permanent magnet synchronous motor position servosystem is given to demonstrate the effectiveness of the proposedcontrol scheme.展开更多
Optical fiber temperature sensors have been widely employed in enormous areas ranging from electric power industry,medical treatment,ocean dynamics to aerospace.Recently,graphene optical fiber temperature sensors attr...Optical fiber temperature sensors have been widely employed in enormous areas ranging from electric power industry,medical treatment,ocean dynamics to aerospace.Recently,graphene optical fiber temperature sensors attract tremendous attention for their merits of simple structure and direct power detecting ability.However,these sensors based on transfer techniques still have limitations in the relatively low sensitivity or distortion of the transmission characteristics,due to the unsuitable Fermi level of graphene and the destruction of fiber structure,respectively.Here,we propose a tunable and highly sensitive temperature sensor based on graphene photonic crystal fiber(Gr-PCF)with the non-destructive integration of graphene into the holes of PCF.This hybrid structure promises the intact fiber structure and transmission mode,which efficiently enhances the temperature detection ability of graphene.From our simulation,we find that the temperature sensitivity can be electrically tuned over four orders of magnitude and achieve up to~3.34×10^(-3) dB/(cm·℃)when the graphene Fermi level is~35 meV higher than half the incident photon energy.Additionally,this sensitivity can be further improved by~10 times through optimizing the PCF structure(such as the fiber hole diameter)to enhance the light–matter interaction.Our results provide a new way for the design of the highly sensitive temperature sensors and broaden applications in all-fiber optoelectronic devices.展开更多
Carrier lifetime is one of the most fundamental physical parameters that characterizes the average time of carrier recombination in any material.The control of carrier lifetime is the key to optimizing the device func...Carrier lifetime is one of the most fundamental physical parameters that characterizes the average time of carrier recombination in any material.The control of carrier lifetime is the key to optimizing the device function by tuning the electro-optical conversion quantum yield,carrier diffusion length,carrier collection process,etc.Till now,the prevailing modulation methods are mainly by defect engineering and temperature control,which have limitations in the modulation direction and amplitude of the carrier lifetime.Here,we report an effective modulation on the ultrafast dynamics of photoexcited carriers in two-dimensional(2D)MoS2 monolayer by uniaxial tensile strain.The combination of optical ultrafast pump-probe technique and time-resolved photoluminescence(PL)spectroscopy reveals that the carrier dynamics through Auger scattering,carrier-phonon scattering,and radiative recombination keep immune to the strain.But strikingly,the uniaxial tensile strain weakens the trapping of photoexcited carriers by defects and therefore prolongs the corresponding carrier lifetime up to 440%per percent applied strain.Our results open a new avenue to enlarge the carrier lifetime of 2D MoS2,which will facilitate its applications in high-efficient optoelectronic and photovoltaic devices.展开更多
The aim of the paper is to explore whether AMPK/U1K1 signaling pathway is involved in regulating autophagy and alleviating cerebral ischemia/reperfusion(I/R)injury.On this basis,study the regulatory effect of Buyang H...The aim of the paper is to explore whether AMPK/U1K1 signaling pathway is involved in regulating autophagy and alleviating cerebral ischemia/reperfusion(I/R)injury.On this basis,study the regulatory effect of Buyang Huanwu Decoction(BHD)on AMPK/U1K1 signaling pathway,aiming to clarify the molecular mechanism of BHD in alleviating cerebral I/R injury and the protective effect of BHD containing serum(BHDS)on OGD/R neurons.The research group adopted the following methods:Neurons cultured for 7 days in vitro were randomly divided into normal control group,model group(OGD/R),AMPK activator(AICAR)group(3 mmol/L),Buyang Huanwu Decoction medicated serum(BHDS)group(3%),Buyang Huanwu Decoction medicated serum+AMPK activator(BHDS+AICAR)group.The protein expressions of p-AMPK,AMPK,p-UlKl,U1K1,Beclin-1 and LC3B in neurons were detected by Western blot,the fluorescence intensity and apoptosis rate of neuron autophagosome CYTO-ID staining were detected by flow cytometry,the fluorescence intensity and morphological changes of neuron LC3B were detected by immunofluorescence double labeling method,the morphological changes of neurons were observed by inverted microscope,and the survival rate of neurons was detected by CCK-8 method.Neuron OGD/R model and the optimal concentration of BHDS.The neurons in the model group were subjected to hypoxia and glucose deprivation for 1 h,2 h,3 h,4 h and reoxygenation and glucose deprivation for 24 h.The survival rate of neurons and the release rate of 1DH to determine whether the model was successfully established.And the results show that BHDS group,the survival rate of OGD/R neurons was significantly increased,and the apoptosis rate was significantly decreased.Among them,3%BHDS intervention at the same time of hypoxia glucose deprivation for 3 h and reoxygenation glucose for 24 h was the best condition.In BHDS group,the levels of p-AMPK/AMPK,p-UlKl/UlKl,beclin-1,CYTO-ID and LC3B fluorescence intensity,and the transformation from LC3B-I to LC3B-II of OGD/R neurons were significantly decreased.So we can draw a conclusion that BHD can inhibit autophagy and alleviate cerebral I/R injury through AMPK/U1K1 signaling pathway.展开更多
The paper presents an alternative approach to explain why regional productivity is different across regions by utilizing the creative class approach in China. First, we analyze the extent of spatial agglomeration of t...The paper presents an alternative approach to explain why regional productivity is different across regions by utilizing the creative class approach in China. First, we analyze the extent of spatial agglomeration of the creative class across regions in China. Second, we develop a model with spatial externalities to investigate how the concentration of the creative class can promote regional productivity. Our analysis confirms the importance of spatial agglomeration of the creative class in stimulating regional productivity. The results also imply that regional productivity is greater in markets with higher levels of innovation, capital stock, manufacturing and urbanization. In light of the results of our analysis, we discuss a number of policy implications.展开更多
The development of biochar has triggered a hot-spot in various research fields including agriculture,energy,environment,and materials.Biochar-based materials provide a novel approach against environmental challenging ...The development of biochar has triggered a hot-spot in various research fields including agriculture,energy,environment,and materials.Biochar-based materials provide a novel approach against environmental challenging issues.Considering the rapid development of biochar materials,this review serves as a valuable platform to summarize the recent progress on the theoretical investigation and engineering applications of biochar materials in environmental remediation.For a better understanding of the structure-application relationships,the structural properties of biochar from macroscopic and microscopic aspects are summarized.The multilevel structures including elements,phases,surface chemistry,and molecular are highlighted to elucidate the multi-functional properties of biochars.Sorption,catalysis,redox reaction,and biological activity of biochar are briefly illustrated,which influence the transport,transformation,and removal of organic and inorganic pollutants in the environments.According to the multi-level structures and structure-application relationships of biochar,specific biochar-based materials and devices have been designed for practical environmental application.The important progress on the functionalization and device of biochar-based materials,including magnetic biochars,2D and 3D biochar-based macrostructures,immobilized microorganism on biochar,and biochar-amended biofilters are highlighted.The environmental friendliness and sustainability of biochar-based materials,considering the whole cycle from synthesis to application,are evaluated.展开更多
Background and Originality Content As an inexpensive,fundamental and important feedstock for the petrochemical industry,methylarenes have long been regarded as one of the most widely used raw materials for a great var...Background and Originality Content As an inexpensive,fundamental and important feedstock for the petrochemical industry,methylarenes have long been regarded as one of the most widely used raw materials for a great variety of organic transformations.Therefore,the selective benzylic C(sp3)—H functionalization is particularly important,which provides a strategic means to utilize this resource.展开更多
Strong geometrical confinement and reduced dielectric screening of two-dimensional(2D)materials leads to strong Coulomb interaction and eventually give rise to extraordinary excitonic effects,which dominates the optic...Strong geometrical confinement and reduced dielectric screening of two-dimensional(2D)materials leads to strong Coulomb interaction and eventually give rise to extraordinary excitonic effects,which dominates the optical and optoelectronic properties.For nonlinear 2D photonic or optoelectronic applications,excitonic effects have been proved effective to tune the light-matter interaction strength.However,the modulation of excitonic effects on the other aspect of nonlinear response,i.e.,polarization dependence,has not been fully explored yet.Here we report the first systemic study on the modulation of excitonic effects on the polarization dependence of second and third harmonic generation(SHG and THG)in strained monolayer WS2 by varying excitation wavelength.We demonstrated that polarization-dependent THG patterns undergo a giant evolution near two-photon excitonic resonance,where the long-axis of the parallel component(originally parallel to the strain direction)has a 90°flip when the excitation wavelength increases.In striking contrast,no apparent variation of polarization-dependent SHG patterns occurs at either two-or three-photon excitonic resonance conditions.Our results open a new avenue to modulate the anisotropic nonlinear optical response of 2D materials through effective control of excitonic resonance states,and thus open opportunity for new designs and applications in nonlinear optoelectronic 2D devices.展开更多
Non-coding RNAs(ncRNAs)have attracted wide attention in the field of ionizing radiation(IR).They have been found to be involved in cell development,proliferation,differentiation,and apoptosis in both clinical radiothe...Non-coding RNAs(ncRNAs)have attracted wide attention in the field of ionizing radiation(IR).They have been found to be involved in cell development,proliferation,differentiation,and apoptosis in both clinical radiotherapy and radiation protection studies.Despite the production of an increasing number of relevant reports in recent years,the molecular mechanisms involved are yet to be clearly understood.In the last few years,ncRNAs have received a lot of research attention,especially microRNAs,long noncoding RNAs,and circular RNAs,which have a well-known association with the development of human disease and are closely related to the biological phenotypic changes caused by IR.With recent developments of research methods,these ncRNAs might play a significant regulatory role in future radiation protection and radiotherapy.This review will summarize the research progress of various types of ncRNAs as biomarkers of IR and potential new targets for radiotherapy,aiming to provide references for future research and the formulation of new strategies.展开更多
基金This work was supported in part by the Fujian Provincial Natural Science Foundation of China under Grant 2017J01747.
文摘This paper presents a discrete-time design of robust compositenonlinear controller to achieve fast and accurate set-pointtracking for motor servo systems subject to actuator saturationand disturbances.The basic idea here is to use a combination oflinear and nonlinear control,together with a disturbancerejection mechanism based on extended state observer.The linearcontrol part is designed to yield a fast response,and thenonlinear part serves to reduce the overshoot,while the extendedstate observer estimates simultaneously the state vector and theunknown disturbance for control and compensation.The closed-loopstability is analyzed using the Lyapunov theory.Practicalapplication in a permanent magnet synchronous motor position servosystem is given to demonstrate the effectiveness of the proposedcontrol scheme.
基金Project supported by the National Natural Science Foundation of China(Grant Nos.52021006,52025023,51991342,and 11888101)the Key R&D Program of Guangdong Province,China(Grant Nos.2019B010931001,2020B010189001,and 2018B030327001)+6 种基金the Pearl River Talent Recruitment Program of Guangdong Province,China(Grant No.2019ZT08C321)the Strategic Priority Research Program of Chinese Academy of Sciences(Grant No.XDB33000000)Beijing Natural Science Foundation,China(Grant No.JQ19004)Beijing Municipal Science&Technology Commission,China(Grant No.Z181100004818003)the China Postdoctoral Science Foundation(Grant No.2020M680177)National Postdoctoral Program for Innovative Talents of China(Grant No.BX20190016)China Postdoctoral Science Foundation(Grant No.2019M660280).
文摘Optical fiber temperature sensors have been widely employed in enormous areas ranging from electric power industry,medical treatment,ocean dynamics to aerospace.Recently,graphene optical fiber temperature sensors attract tremendous attention for their merits of simple structure and direct power detecting ability.However,these sensors based on transfer techniques still have limitations in the relatively low sensitivity or distortion of the transmission characteristics,due to the unsuitable Fermi level of graphene and the destruction of fiber structure,respectively.Here,we propose a tunable and highly sensitive temperature sensor based on graphene photonic crystal fiber(Gr-PCF)with the non-destructive integration of graphene into the holes of PCF.This hybrid structure promises the intact fiber structure and transmission mode,which efficiently enhances the temperature detection ability of graphene.From our simulation,we find that the temperature sensitivity can be electrically tuned over four orders of magnitude and achieve up to~3.34×10^(-3) dB/(cm·℃)when the graphene Fermi level is~35 meV higher than half the incident photon energy.Additionally,this sensitivity can be further improved by~10 times through optimizing the PCF structure(such as the fiber hole diameter)to enhance the light–matter interaction.Our results provide a new way for the design of the highly sensitive temperature sensors and broaden applications in all-fiber optoelectronic devices.
基金Project supported by the Natural Science Foundation of Beijing,China(Grant No.JQ19004)the Excellent Talents Training Support Fund of Beijing,China(Grant No.2017000026833ZK11)+7 种基金the National Natural Science Foundation of China(Grant Nos.51991340 and 51991342)the National Key Research and Development Program of China(Grant Nos.2016YFA0300903 and 2016YFA0300804)the Key Research and Development Program of Guangdong Province,China(Grant Nos.2019B010931001,2020B010189001,2018B010109009,and 2018B030327001)the Science Fund from the Municipal Science&Technology Commission of Beijing,China(Grant No.Z191100007219005)the Graphene Innovation Program of Beijing,China(Grant No.Z181100004818003)the Fund from the Bureau of Industry and Information Technology of Shenzhen City,China(Graphene platform 201901161512)the Innovative and Entrepreneurial Research Team Program of Guangdong Province,China(Grant No.2016ZT06D348)the Fund from the Science,Technology,and Innovation Commission of Shenzhen Municipality,China(Grant No.KYTDPT20181011104202253).
文摘Carrier lifetime is one of the most fundamental physical parameters that characterizes the average time of carrier recombination in any material.The control of carrier lifetime is the key to optimizing the device function by tuning the electro-optical conversion quantum yield,carrier diffusion length,carrier collection process,etc.Till now,the prevailing modulation methods are mainly by defect engineering and temperature control,which have limitations in the modulation direction and amplitude of the carrier lifetime.Here,we report an effective modulation on the ultrafast dynamics of photoexcited carriers in two-dimensional(2D)MoS2 monolayer by uniaxial tensile strain.The combination of optical ultrafast pump-probe technique and time-resolved photoluminescence(PL)spectroscopy reveals that the carrier dynamics through Auger scattering,carrier-phonon scattering,and radiative recombination keep immune to the strain.But strikingly,the uniaxial tensile strain weakens the trapping of photoexcited carriers by defects and therefore prolongs the corresponding carrier lifetime up to 440%per percent applied strain.Our results open a new avenue to enlarge the carrier lifetime of 2D MoS2,which will facilitate its applications in high-efficient optoelectronic and photovoltaic devices.
基金the National Natural Science Foundation of China(81873180)the general program of the Natural Science Foundation of Hebei Province(H2019423074)+1 种基金the key program of Hebei University of Traditional Chinese Medicine(KTZ2019018)the central guiding local science and technology development fund(206Z7706G).
文摘The aim of the paper is to explore whether AMPK/U1K1 signaling pathway is involved in regulating autophagy and alleviating cerebral ischemia/reperfusion(I/R)injury.On this basis,study the regulatory effect of Buyang Huanwu Decoction(BHD)on AMPK/U1K1 signaling pathway,aiming to clarify the molecular mechanism of BHD in alleviating cerebral I/R injury and the protective effect of BHD containing serum(BHDS)on OGD/R neurons.The research group adopted the following methods:Neurons cultured for 7 days in vitro were randomly divided into normal control group,model group(OGD/R),AMPK activator(AICAR)group(3 mmol/L),Buyang Huanwu Decoction medicated serum(BHDS)group(3%),Buyang Huanwu Decoction medicated serum+AMPK activator(BHDS+AICAR)group.The protein expressions of p-AMPK,AMPK,p-UlKl,U1K1,Beclin-1 and LC3B in neurons were detected by Western blot,the fluorescence intensity and apoptosis rate of neuron autophagosome CYTO-ID staining were detected by flow cytometry,the fluorescence intensity and morphological changes of neuron LC3B were detected by immunofluorescence double labeling method,the morphological changes of neurons were observed by inverted microscope,and the survival rate of neurons was detected by CCK-8 method.Neuron OGD/R model and the optimal concentration of BHDS.The neurons in the model group were subjected to hypoxia and glucose deprivation for 1 h,2 h,3 h,4 h and reoxygenation and glucose deprivation for 24 h.The survival rate of neurons and the release rate of 1DH to determine whether the model was successfully established.And the results show that BHDS group,the survival rate of OGD/R neurons was significantly increased,and the apoptosis rate was significantly decreased.Among them,3%BHDS intervention at the same time of hypoxia glucose deprivation for 3 h and reoxygenation glucose for 24 h was the best condition.In BHDS group,the levels of p-AMPK/AMPK,p-UlKl/UlKl,beclin-1,CYTO-ID and LC3B fluorescence intensity,and the transformation from LC3B-I to LC3B-II of OGD/R neurons were significantly decreased.So we can draw a conclusion that BHD can inhibit autophagy and alleviate cerebral I/R injury through AMPK/U1K1 signaling pathway.
基金the support of the National Natural Science Foundation ofChina(71172213 and 71171183)the Ministry of Education,Humanities and Social Sciences Project(09YJA630153 and 10YJA790260)the National Social Science Foundation of China(08&ZD043)
文摘The paper presents an alternative approach to explain why regional productivity is different across regions by utilizing the creative class approach in China. First, we analyze the extent of spatial agglomeration of the creative class across regions in China. Second, we develop a model with spatial externalities to investigate how the concentration of the creative class can promote regional productivity. Our analysis confirms the importance of spatial agglomeration of the creative class in stimulating regional productivity. The results also imply that regional productivity is greater in markets with higher levels of innovation, capital stock, manufacturing and urbanization. In light of the results of our analysis, we discuss a number of policy implications.
基金This project was supported by the National Natural Science Foundations of China(21621005,and 21537005,21425730)the National Key Technology Research and Development Program of China(2018YFC1800705).
文摘The development of biochar has triggered a hot-spot in various research fields including agriculture,energy,environment,and materials.Biochar-based materials provide a novel approach against environmental challenging issues.Considering the rapid development of biochar materials,this review serves as a valuable platform to summarize the recent progress on the theoretical investigation and engineering applications of biochar materials in environmental remediation.For a better understanding of the structure-application relationships,the structural properties of biochar from macroscopic and microscopic aspects are summarized.The multilevel structures including elements,phases,surface chemistry,and molecular are highlighted to elucidate the multi-functional properties of biochars.Sorption,catalysis,redox reaction,and biological activity of biochar are briefly illustrated,which influence the transport,transformation,and removal of organic and inorganic pollutants in the environments.According to the multi-level structures and structure-application relationships of biochar,specific biochar-based materials and devices have been designed for practical environmental application.The important progress on the functionalization and device of biochar-based materials,including magnetic biochars,2D and 3D biochar-based macrostructures,immobilized microorganism on biochar,and biochar-amended biofilters are highlighted.The environmental friendliness and sustainability of biochar-based materials,considering the whole cycle from synthesis to application,are evaluated.
基金The authors thank the National Key Research and Development Program of China(No.2016 YFA 0602900),the National Natural Science Foundation of Chin a(No.21420102003)Guangdong Province Science Foundation(No.2017 B 090903003)for financial support.
文摘Background and Originality Content As an inexpensive,fundamental and important feedstock for the petrochemical industry,methylarenes have long been regarded as one of the most widely used raw materials for a great variety of organic transformations.Therefore,the selective benzylic C(sp3)—H functionalization is particularly important,which provides a strategic means to utilize this resource.
基金This work was supported by The Key R&D Program of Guangdong Province(Nos.2019B010931001,2020B010189001,2018B010109009,and 2018B030327001)the National Natural Science Foundation of China(Nos.51991340 and 51991342)+7 种基金the National Key R&D Program of China(Nos.2016YFA0300903 and 2016YFA0300804)Beijing Natural Science Foundation(No.JQ19004)Beijing Excellent Talents Training Support(No.2017000026833ZK11)Beijing Municipal Science&Technology Commission(No.Z191100007219005)Beijing Graphene Innovation Program(No.Z181100004818003)Bureau of Industry and Information Technology of Shenzhen(Graphene platform 201901161512)Guangdong Innovative and Entrepreneurial Research Team Program(No.2016ZT06D348)the Science,Technology and Innovation Commission of Shenzhen Municipality(No.KYTDPT20181011104202253).
文摘Strong geometrical confinement and reduced dielectric screening of two-dimensional(2D)materials leads to strong Coulomb interaction and eventually give rise to extraordinary excitonic effects,which dominates the optical and optoelectronic properties.For nonlinear 2D photonic or optoelectronic applications,excitonic effects have been proved effective to tune the light-matter interaction strength.However,the modulation of excitonic effects on the other aspect of nonlinear response,i.e.,polarization dependence,has not been fully explored yet.Here we report the first systemic study on the modulation of excitonic effects on the polarization dependence of second and third harmonic generation(SHG and THG)in strained monolayer WS2 by varying excitation wavelength.We demonstrated that polarization-dependent THG patterns undergo a giant evolution near two-photon excitonic resonance,where the long-axis of the parallel component(originally parallel to the strain direction)has a 90°flip when the excitation wavelength increases.In striking contrast,no apparent variation of polarization-dependent SHG patterns occurs at either two-or three-photon excitonic resonance conditions.Our results open a new avenue to modulate the anisotropic nonlinear optical response of 2D materials through effective control of excitonic resonance states,and thus open opportunity for new designs and applications in nonlinear optoelectronic 2D devices.
基金the Collaborative Innovation Center of Radiological Medicine of Jiangsu Higher Education Institutions,the Priority Academic Program Development of Jiangsu Higher Education Institutions(PAPD)China,and the Nuclear Energy Development Project,China(No.2016-1295).
文摘Non-coding RNAs(ncRNAs)have attracted wide attention in the field of ionizing radiation(IR).They have been found to be involved in cell development,proliferation,differentiation,and apoptosis in both clinical radiotherapy and radiation protection studies.Despite the production of an increasing number of relevant reports in recent years,the molecular mechanisms involved are yet to be clearly understood.In the last few years,ncRNAs have received a lot of research attention,especially microRNAs,long noncoding RNAs,and circular RNAs,which have a well-known association with the development of human disease and are closely related to the biological phenotypic changes caused by IR.With recent developments of research methods,these ncRNAs might play a significant regulatory role in future radiation protection and radiotherapy.This review will summarize the research progress of various types of ncRNAs as biomarkers of IR and potential new targets for radiotherapy,aiming to provide references for future research and the formulation of new strategies.