Digital twinning enables manufacturers to create digital representations of physical entities,thus implementing virtual simulations for product development.Previous efforts of digital twinning neglect the decisive con...Digital twinning enables manufacturers to create digital representations of physical entities,thus implementing virtual simulations for product development.Previous efforts of digital twinning neglect the decisive consumer feedback in product development stages,failing to cover the gap between physical and digital spaces.This work mines real-world consumer feedbacks through social media topics,which is significant to product development.We specifically analyze the prevalent time of a product topic,giving an insight into both consumer attention and the widely-discussed time of a product.The primary body of current studies regards the prevalent time prediction as an accompanying task or assumes the existence of a preset distribution.Therefore,these proposed solutions are either biased in focused objectives and underlying patterns or weak in the capability of generalization towards diverse topics.To this end,this work combines deep learning and survival analysis to predict the prevalent time of topics.We propose a specialized deep survival model which consists of two modules.The first module enriches input covariates by incorporating latent features of the time-varying text,and the second module fully captures the temporal pattern of a rumor by a recurrent network structure.Moreover,a specific loss function different from regular survival models is proposed to achieve a more reasonable prediction.Extensive experiments on real-world datasets demonstrate that our model significantly outperforms the state-of-the-art methods.展开更多
The security performance of cloud services is a key factor influencing users’selection of Cloud Service Providers(CSPs).Continuous monitoring of the security status of cloud services is critical.However,existing rese...The security performance of cloud services is a key factor influencing users’selection of Cloud Service Providers(CSPs).Continuous monitoring of the security status of cloud services is critical.However,existing research lacks a practical framework for such ongoing monitoring.To address this gap,this paper proposes the first NonCollaborative Container-Based Cloud Service Operation State Continuous Monitoring Framework(NCCMF),based on relevant standards.NCCMF operates without the CSP’s collaboration by:1)establishing a scalable supervisory index system through the identification of security responsibilities for each role,and 2)designing a Continuous Metrics Supervision Protocol(CMA)to automate the negotiation of supervisory metrics.The framework also outlines the supervision process for cloud services across different deployment models.Experimental results demonstrate that NCCMF effectively monitors the operational state of two real-world IoT(Internet of Things)cloud services,with an average supervision error of less than 15%.展开更多
Background:The aim of the study was to investigate the changes in the periarterial capillary-free zone(paCFZ)after anti-vascular endothelial growth factor(VEGF)therapy in patients with branch retinal vein occlusion(BR...Background:The aim of the study was to investigate the changes in the periarterial capillary-free zone(paCFZ)after anti-vascular endothelial growth factor(VEGF)therapy in patients with branch retinal vein occlusion(BRVO)by widefield swept-source optical coherence tomography angiography(SS-OCTA)and assess their associations with clinical outcomes.Methods:In this retrospective observational study of 54 treatment-naive BRVO patients with macular edema,we reviewed the findings of 12×12 mm^(2)SS-OCTA at baseline,3,6,and 12 months after intravitreal ranibizumab injections.The paCFZ and major retinal artery areas were measured on SS-OCTA images.The paCFZ area to artery area(P/A)ratio was calculated.Results:The paCFZ areas and P/A ratios of first-and second-order arteries were significantly greater in BRVO eyes than in contralateral eyes(all P<0.01),but there were no differences in the first-and second-order artery areas(P=0.20 and 0.25,respectively).The paCFZ areas and P/A ratios decreased significantly at 3,6,and 12 months after anti-VEGF therapy(all P<0.01).The baseline P/A ratio was significantly correlated with the baseline best-corrected visual acuity(BCVA),central retinal thickness,and their improvements at 3,6,and 12 months(all P<0.05).Baseline BCVA and P/A ratios of first-and second-order arteries were independently associated with the final BCVA in multivariate linear regression.Conclusions:Wide-field SS-OCTA shows that anti-VEGF therapy can lead to a significant improvement in the paCFZ parameters in BRVO.Smaller baseline P/A ratios on SS-OCTA tend to predict better visual outcomes at 12 months after anti-VEGF therapy.展开更多
Severe coronavirus 2019 (COVID-19) infection is associated with myocardial injury and arrhythmia. Bradycardia is a newly recognized consequence of COVID-19. Relative bradycardia and its effects in 4 critically ill pat...Severe coronavirus 2019 (COVID-19) infection is associated with myocardial injury and arrhythmia. Bradycardia is a newly recognized consequence of COVID-19. Relative bradycardia and its effects in 4 critically ill patients with COVID-19 was described in this case series. The 4 cases showed the same clinical phenomenon: sinus bradycardia without a compensatory increase in heart rate in response to elevation of body temperature. Typically, heart rate decreases as body temperature rises. The 4 patients were all men with an average age of 67 years. Patient 1 was a 78-year-old man with no major medical history who died from COVID-19 pneumonia. The other 3 patients recovered.展开更多
基金supported by Sichuan Science and Technology Program(Nos.2019YFG0507,2020YFG0328 and 2021YFG0018)by National Natural Science Foundation of China(NSFC)under Grant No.U19A2059+1 种基金by the Young Scientists Fund of the National Natural Science Foundation of China under Grant No.61802050by the Fundamental Research Funds for the Central Universities(No.ZYGX2021J019).
文摘Digital twinning enables manufacturers to create digital representations of physical entities,thus implementing virtual simulations for product development.Previous efforts of digital twinning neglect the decisive consumer feedback in product development stages,failing to cover the gap between physical and digital spaces.This work mines real-world consumer feedbacks through social media topics,which is significant to product development.We specifically analyze the prevalent time of a product topic,giving an insight into both consumer attention and the widely-discussed time of a product.The primary body of current studies regards the prevalent time prediction as an accompanying task or assumes the existence of a preset distribution.Therefore,these proposed solutions are either biased in focused objectives and underlying patterns or weak in the capability of generalization towards diverse topics.To this end,this work combines deep learning and survival analysis to predict the prevalent time of topics.We propose a specialized deep survival model which consists of two modules.The first module enriches input covariates by incorporating latent features of the time-varying text,and the second module fully captures the temporal pattern of a rumor by a recurrent network structure.Moreover,a specific loss function different from regular survival models is proposed to achieve a more reasonable prediction.Extensive experiments on real-world datasets demonstrate that our model significantly outperforms the state-of-the-art methods.
基金supported in part by the Intelligent Policing and National Security Risk Management Laboratory 2023 Opening Project(No.ZHKFYB2304)the Fundamental Research Funds for the Central Universities(Nos.SCU2023D008,2023SCU12129)+2 种基金the Natural Science Foundation of Sichuan Province(No.2024NSFSC1449)the Science and Engineering Connotation Development Project of Sichuan University(No.2020SCUNG129)the Key Laboratory of Data Protection and Intelligent Management(Sichuan University),Ministry of Education.
文摘The security performance of cloud services is a key factor influencing users’selection of Cloud Service Providers(CSPs).Continuous monitoring of the security status of cloud services is critical.However,existing research lacks a practical framework for such ongoing monitoring.To address this gap,this paper proposes the first NonCollaborative Container-Based Cloud Service Operation State Continuous Monitoring Framework(NCCMF),based on relevant standards.NCCMF operates without the CSP’s collaboration by:1)establishing a scalable supervisory index system through the identification of security responsibilities for each role,and 2)designing a Continuous Metrics Supervision Protocol(CMA)to automate the negotiation of supervisory metrics.The framework also outlines the supervision process for cloud services across different deployment models.Experimental results demonstrate that NCCMF effectively monitors the operational state of two real-world IoT(Internet of Things)cloud services,with an average supervision error of less than 15%.
基金supported by grants from the National Natural Science Foundation of China(Grant Nos.82101150,82171078)Shanghai clinical 3-year action plan-major clinical research(Grant Nos.SHDC2020CR2041B,SHDC2020CR5014-003)+1 种基金Shanghai Sailing Program(Grant No.21YF1405300)Shanghai Committee of Science and Technology(Grant Nos.20Y11911100,18411965100).
文摘Background:The aim of the study was to investigate the changes in the periarterial capillary-free zone(paCFZ)after anti-vascular endothelial growth factor(VEGF)therapy in patients with branch retinal vein occlusion(BRVO)by widefield swept-source optical coherence tomography angiography(SS-OCTA)and assess their associations with clinical outcomes.Methods:In this retrospective observational study of 54 treatment-naive BRVO patients with macular edema,we reviewed the findings of 12×12 mm^(2)SS-OCTA at baseline,3,6,and 12 months after intravitreal ranibizumab injections.The paCFZ and major retinal artery areas were measured on SS-OCTA images.The paCFZ area to artery area(P/A)ratio was calculated.Results:The paCFZ areas and P/A ratios of first-and second-order arteries were significantly greater in BRVO eyes than in contralateral eyes(all P<0.01),but there were no differences in the first-and second-order artery areas(P=0.20 and 0.25,respectively).The paCFZ areas and P/A ratios decreased significantly at 3,6,and 12 months after anti-VEGF therapy(all P<0.01).The baseline P/A ratio was significantly correlated with the baseline best-corrected visual acuity(BCVA),central retinal thickness,and their improvements at 3,6,and 12 months(all P<0.05).Baseline BCVA and P/A ratios of first-and second-order arteries were independently associated with the final BCVA in multivariate linear regression.Conclusions:Wide-field SS-OCTA shows that anti-VEGF therapy can lead to a significant improvement in the paCFZ parameters in BRVO.Smaller baseline P/A ratios on SS-OCTA tend to predict better visual outcomes at 12 months after anti-VEGF therapy.
文摘Severe coronavirus 2019 (COVID-19) infection is associated with myocardial injury and arrhythmia. Bradycardia is a newly recognized consequence of COVID-19. Relative bradycardia and its effects in 4 critically ill patients with COVID-19 was described in this case series. The 4 cases showed the same clinical phenomenon: sinus bradycardia without a compensatory increase in heart rate in response to elevation of body temperature. Typically, heart rate decreases as body temperature rises. The 4 patients were all men with an average age of 67 years. Patient 1 was a 78-year-old man with no major medical history who died from COVID-19 pneumonia. The other 3 patients recovered.