Dual-ion carrier storage through Mg^(2+) addition for high-energy and long-life zinc-ion hybrid capacitor

Cation additives can efficiently enhance the total electrochemical capabilities of zinc-ion hybrid capacitors (ZHCs).However their energy storage mechanisms in zinc-based systems are still under debate.Herein,we modulate the electrolyte and achieve dual-ion storage by adding magnesium ions.And we assemble several Zn//activated carbon devices with different electrolyte concentrations and investigate their electrochemical reaction dynamic behaviors.The zinc-ion capacitor with Mg^(2+)mixed solution delivers 82 mAh·g^(-1)capacity at 1 A·g^(-1) and maintains 91%of the original capacitance after 10000 cycling.It is superior to the other assembled zinc-ion devices in single-component electrolytes.The finding demonstrates that the double-ion storage mechanism enables the superior rate performance and long cycle lifetime of ZHCs.

Anomalous{1012}tensile twinning and subsequent detwinning in a friction stir processed carbon fiber-reinforced Mg composite

1.Main text Owing to their low density and high specific strength,magnesium alloys and magnesium-based composites have great potential as structure metal materials in applications where lightweight matters[1–4].Deformation twins[5],especially the{1012}tension twins(also called tensile or extension twins)with a low critical resolved shear stress(CRSS)[6],are commonly observed in Mg alloys.They can provide the much-needed deformation along the c-axis in their hcp structure resulting from the very few easily activated slip systems in this crystal structure[7].The tensile twinning activation usually follows the macroscopic Schmid factor law[2],i.e.,the twin variant with the highest Schmid factor occurs,and it only appears when its Schmid factor is positive.

Imaging, pathology, and diagnosis of solitary fibrous tumor of the pancreas: A case report and review of literature

BACKGROUND A solitary fibrous tumor(SFT)is often located in the pleura,while SFT of the pancreas is extremely rare.Here,we report a case of SFT of the pancreas and discuss imaging,histopathology,and immunohistochemistry for accurate diagnosis and treatment.CASE SUMMARY A 54-year-old man presented to our hospital with pancreatic occupancy for over a month.There were no previous complaints of discomfort.His blood pressure was normal.Blood glucose,tumor markers,and enhanced computed tomography(CT)suggested a malignant tumor.Because the CT appearance of pancreatic cancer varies,we could not confirm the diagnosis;therefore,we performed endoscopic ultrasound-guided fine-needle biopsy(EUS-FNB).Pathology and immunohistochemistry were consistent with SFT of the pancreas.The posto-perative pathology and immunohistochemistry were consistent with the puncture results.The patient presented for a follow-up examination one month after discharge with no adverse effects.CONCLUSION Other diseases must be excluded in patients with a pancreatic mass that cannot be diagnosed.CT and pathological histology have diagnostic value for pancreatic tumors.Endoscopic puncture biopsy under ultrasound can help diagnose pancreatic masses that cannot be diagnosed preoperatively.Surgery is an effective treatment for SFT of the pancreas;however,long-term follow-up is strongly recommended because of the possibility of malignant transformation of the tumor.

基于多目标区域地球化学调查的矿产资源潜力评价——以鄂东大别山地区为例

区域地球化学勘探在地质找矿中具有显著的应用效果,可以充分利用多目标区域地球化学调查数据进行找矿预测。基于鄂东大别山地区多目标区域地球化学调查数据,系统分析表层土壤中54项指标的背景、分布及组合特征,然后重点圈定与矿产有关的多元素组合异常,并结合各组合异常区的地质背景及已有矿床特征,初步提出成矿预测区。结果表明,①与湖北省土壤背景值相比,研究区表层土壤中Ba、Cl、Sr、CaO、Na_(2)O等5项指标表现为强富集,La、P表现为富集,Be、Ce、F、Ga、Ge、Mn、Nb、Pb、Sc、Th、Ti、V、Y、Zn、Zr、SiO_(2)、Al_(2)O_(3)、TFe_(2)O_(3)、MgO、K_(2)O、pH等21项指标与之相当,Ag、Bi、Br、Cd、Co、Cr、Cu、I、Mo、N、Ni、Rb、S、Se、Sn、Tl、U、Corg、TC等19项指标表现为贫乏,Au、As、B、Hg、Li、Sb、W等7项指标表现为极贫乏;②圈定多元素组合异常41处,其中与Au、Ag、As、Sb、Hg有关的组合异常13处,与Fe、Co、Ni、V、Ti有关的组合异常10处,与U、Th、Nb、Ce、La有关的组合异常8处,与W、Mo、Bi、Sn、Pb有关的组合异常10处;③初步提出10个成矿预测区,分别为宣化金银钨钼铅锌成矿预测区、新城金银铁重稀土成矿预测区、七里坪金银铜钼成矿预测区、华家河金银铅铁镍重晶石萤石成矿预测区、夏店钨钼铀成矿预测区、三河口银铁镍成矿预测区、三里畈金银铜铅重稀土成矿预测区、杨柳湾铜钼成矿预测区、南河铁铜钼成矿预测区、张榜金银铁铜钼磷成矿预测区。研究成果可以为鄂东大别山地区开展下步找矿工作部署提供一定的参考。

Research Progress on the Association between Schizophrenia and Toxoplasma gondii Infection

Toxoplasma gondii(T.gondii or Tg),is an obligatory intracellular parasite with humans as its intermediate hosts.In recent years,significant correlations between T.gondii infection and schizophrenia have been reported,including the possible mediating mechanisms.Currently,mechanisms and hypotheses focus on central neurotransmitters,immunity,neuroinflammation,and epigenetics;however,the exact underlying mechanisms remain unclear.In this article,we review the studies related to T.gondii infection and schizophrenia,particularly the latest research progress.Research on dopamine(DA)and other neurotransmitters,the blood-brain barrier,inflammatory factors,disease heterogeneity,and other confounders is also discussed.In addition,we also summarized the results of some new epidemiological investigations.

Characteristics of the electromagnetic wave propagation in magnetized plasma sheath and practical method for blackout mitigation

“Magnetic window”is considered as an effective method to solve the communication blackout issue.COMSOL software package based on the finite element method is utilized to simulate the propagation of right-handed circularly polarized wave in the magnetized plasma sheath.We assume a double Gaussian model of electron density and an exponential attenuation model of magnetic field.The propagation characteristics of right-handed circularly polarized wave are analyzed by the observation of the reflected,transmitted and loss coefficient.The numerical results show that the propagation of right-handed circularly polarized wave in the magnetized plasma sheath varies for different incident angles,collision frequencies,non-uniform magnetic fields and non-uniform plasma densities.We notice that reducing the wave frequency can meet the propagation conditions of whistle mode in the weak magnetized plasma sheath.And the transmittance of whistle mode is less affected by the variation of the electron density and the collision frequency.It can be used as a communication window.

Fabrication of lightweight 3D interpenetrated NiTi@Mg composite with superior bending properties

A NiTi@Mg interpenetrating phase composite with high strength and lightweight was prepared by additive manufacturing(AM)and infiltration technology,and the interface bonding,three-point bending properties and cyclic compressive properties of NiTi@Mg composites were investigated.The results show that the metallurgically bonded interface is formed at the NiTi/Mg interfaces.The bending strength and compressive strength of the NiTi@Mg composite are 2.5 and 1.7 times higher than those of the NiTi scaffold,respectively.During the bending deformation process,a large number of dislocations are observed to accumulate in the soft Mg area at the interface.Furthermore,the finite element model showed that the stress accumulation area,where the bending crack is initiated,is located at the interface of NiTi and Mg.The strengthening mechanism of NiTi@Mg composites is attributed to the twinning strengthening of Mg and heterogeneous structure strengthening.

In-situ Micro-CT analysis of deformation behavior in sandwich-structured meta-stable beta Ti−35Nb alloy

Beta Ti−35Nb sandwich-structured composites with various reinforcing layers were designed and produced using additive manufacturing(AM)to achieve a balance between light weight and high strength.The impact of reinforcing layers on the compressive deformation behavior of porous composites was investigated through micro-computed tomography(Micro-CT)and finite element method(FEM)analyses.The results indicate that the addition of reinforcement layers to sandwich structures can significantly enhance the compressive yield strength and energy absorption capacity of porous metal structures;Micro-CT in-situ observation shows that the strain of the porous structure without the reinforcing layer is concentrated in the middle region,while the strain of the porous structure with the reinforcing layer is uniformly distributed;FEM analysis reveals that the reinforcing layers can alter stress distribution and reduce stress concentration,thereby promoting uniform deformation of the porous structure.The addition of reinforcing layer increases the compressive yield strength of sandwich-structured composite materials by 124%under the condition of limited reduction of porosity,and the yield strength increases from 4.6 to 10.3 MPa.

Extraction of fractures in shale CT images using improved U-Net

Accurate extraction of pores and fractures is a prerequisite for constructing digital rocks for physical property simulation and microstructural response analysis.However,fractures in CT images are similar in grayscale to the rock matrix,and traditional algorithms have difficulty to achieve accurate segmentation results.In this study,a dataset containing multiscale fracture information was constructed,and a U-Net semantic segmentation model with a scSE attention mechanism was used to classify shale CT images at the pixel level and compare the results with traditional methods.The results showed that the CLAHE algorithm effectively removed noise and enhanced the fracture information in the dark parts,which is beneficial for further fracture extraction.The Canny edge detection algorithm had significant false positives and failed to recognize the internal information of the fractures.The Otsu algorithm only extracted fractures with a significant difference from the background and was not sensitive enough for fine fractures.The MEF algorithm enhanced the edge information of the fractures and was also sensitive to fine fractures,but it overestimated the aperture of the fractures.The U-Net was able to identify almost all fractures with good continuity,with an MIou and Recall of 0.80 and 0.82,respectively.As the image resolution increases,more fine fracture information can be extracted.

A Transfer Learning Framework for Deep Multi-Agent Reinforcement Learning

Dear Editor,This letter presents a new transfer learning framework for the deep multi-agent reinforcement learning(DMARL) to reduce the convergence difficulty and training time when applying DMARL to a new scenario [1], [2].

Lithium carbonate-induced giant goiter and subclinical hyperthyroidism in a patient with schizophrenia:A case report and review of literature

BACKGROUND Lithium carbonate is used to manage various mood disorders,but it can cause thyroid abnormalities,including goiter,hypothyroidism,and hyperthyroidism.In rare cases,it can lead to giant goiter and subclinical hyperthyroidism,which may require surgical intervention in severe cases.CASE SUMMARY This case represents a rare development of giant goiter and subclinical hyperthyroidism in a schizophrenia patient who was subjected to prolonged lithium carbonate treatment.The enlarged thyroid gland caused pressure on the airway and recurrent laryngeal nerve,which led to respiratory distress,hoarseness,and dysphagia.The immediate danger of suffocation required urgent surgical intervention.In this report,we describe the case of a 41-year-old Chinese woman.This sheds light on the etiology and challenges associated with managing a giant goiter.The patient underwent a subtotal thyroidectomy to relieve airway compression and facilitate airway expansion.Prior to the procedure,the patient was given iodine to prepare.Concurrently,changes were made to the psychiatric medication regimen.Following surgery,the patient's respiratory function and vocal cord functionality improved significantly,and her mental state remained stable.CONCLUSION It is essential to monitor thyroid function,test thyroid antibody levels,and perform thyroid ultrasounds consistently in all patients undergoing long-term lithium carbonate treatment.This vigilance helps prevent severe and potentially life-threatening thyroid enlargement.

基于OBE理念的大学生创新实践能力的培养——以合肥工业大学应用化学专业为例

基于成果导向教育(OBE)理念,遵循成果导向教育思路,围绕学生创新实践能力的培养,制定特色鲜明的合肥工业大学应用化学专业人才培养方案,即加强“双师型”师资队伍、搭建创新实践能力的培养与专业教育相结合的“科教、赛教、企教”创新实践平台、建立强化过程考核为导向的教学评价模式。应用化学专业的实践探索对培养具有创新意识和实践能力的复合型人才具有很好的参考价值。

超声波纳米提取测量法——一种覆盖区找矿新技术:在拜仁达坝铅锌矿区的实践

覆盖区寻找隐伏矿是今后找矿工作重要的勘查目标,常用的勘查方法有气体测量法和化学偏提取的方法。这些方法野外工作量大,室内操作复杂,外界干扰因素大,分析测量重现性较差。为此,我们建立了土壤纳米简便提取和测量的新方法——超声波纳米提取测量法,利用超声波空化原理,快速提取土壤中的纳米物质,并在内蒙古半干旱草原区上方开展了超声波纳米提取测量法的地球化学勘查方法的试验工作。结果表明,超声波纳米提取测量法获得的地球化学异常明显,对下伏矿体的指示效果较为明确,其中主要成矿元素Cu、Pb、Zn、Ni、Ag在矿体上方均有明显的异常,且异常衬度与矿体深度的对应关系好。矿体深度浅,异常衬度大,矿体深度深,异常衬度小。超声波纳米提取法可作为该景观区寻找隐伏矿的有效手段。

Teaching Reform and Practice of “Mathematical Analysis” under the New Engineering Education Paradigm

With the advent and promotion of the new engineering education paradigm,university mathematics courses face new challenges and opportunities.As a fundamental course for engineering majors,the reform of“Mathematical Analysis”is particularly crucial.This paper explores the necessity,specific practices,and outcomes of teaching reform in“Mathematical Analysis”within the context of the new engineering education.By reforming teaching content,methods,and assessment approaches,this study aims to enhance students’mathematical literacy and comprehensive abilities to meet the demands of the new engineering education development.

TIM-1和TIM-4 mRNA在HAV患者中的表达及其临床意义

目的观察典型病程甲型病毒性肝炎(HAV)患者外周血中T细胞免疫球蛋白域蛋白-1(TIM-1)和T细胞免疫球蛋白域蛋白-4(TIM-4)mRNA的表达水平,探讨HAV患者病情进展的不同时期TIM-1和TIM-4 mRNA水平与HAV RNA含量,HAV免疫球蛋白M(Ig M)、免疫球蛋白G(Ig G)浓度及肝功能指标的关系。方法选取HAV典型病程的30例患者作为HAV组,分别于潜伏期或黄疸前期、黄疸期及恢复期留取血液标本,以同期30例健康体检者作为对照组,收集血液标本。采用实时荧光定量聚合酶链反应检测TIM-1和TIM-4 mRNA表达水平,同时检测HAV患者外周血HAV RNA含量,酶联免疫吸附法检测HAV患者外周血HAV抗体IgM、IgG滴度水平,全自动生化分析仪检测肝功能指标谷丙转氨酶、谷草转氨酶及总胆红素。结果 HAV组患者外周血TIM-1和TIM-4 mRNA表达水平高于对照组患者(P<0.05)。随着疾病进程的继续,TIM-1及TIM-4 mRNA表达水平于黄疸期达峰值,恢复期下降。TIM-1 mRNA表达水平与HAV患者Ig M滴度、AST及TBIL呈正相关(P<0.05),与Ig G滴度无关(P>0.05)。结论 HAV患者外周血中TIM-1和TIM-4 mRNA的表达水平与HAV的疾病进展有较好的拟合性,TIM-1和TIM-4 mRNA可能在HAV的发生、发展中发挥作用。

甲型肝炎患者黏蛋白域蛋白1和4表达与抗体产生的相关性研究

目的探讨甲型肝炎患者恢复期T细胞免疫球蛋白及黏蛋白域蛋白(TIM)1和4 mRNA水平与体液免疫的关系,了解TIM-1和TIM-4在体液免疫抗体产生过程中的相关作用。方法选取甲型病毒性肝炎典型病程的60例患者于恢复期留取血液标本,以同期60例健康体检志愿者血液标本作为对照,qRTPCR检测TIM-1和TIM-4 mRNA水平,ELISA检测外周血白介素4(IL-4)、白介素10(IL-10)、肿瘤坏死因子α(TNF-α)和血清总Ig(IgG、IgM和IgA)水平。结果甲型病毒性肝炎患者外周血TIM-1及TIM-4 mRNA的表达水平高于对照组(P<0.05);甲型病毒性肝炎患者血清中IL-4和IL-10水平高于对照组(P<0.05);甲型病毒性肝炎患者血清总Ig(IgG、IgM和IgA)水平高于正常对照组(P<0.05)。结论TIM-1及TIM-4水平升高可能通过提高IL-4、IL-10和TNF-α来增强体液免疫的功能。

MicroRNA-21对肺高压血管平滑肌细胞增殖的影响

目的研究micro RNA-21(mi RNA-21)在Wnt/β-catenin信号通路中抑制肺高压(PH)血管平滑肌细胞增殖的可能机制。方法复制外源性mi RNA-21干扰的野百合碱大鼠肺高压原代肺动脉平滑肌细胞(PASMCs)模型,分别用Western blot和实时荧光定量PCR检测外源性mi RNA-21对Wnt通路中β-catenin、Cyclin D1和拮抗剂DDK1表达的影响。结果外源性抑制mi RNA-21表达时,PASMCs中β-catenin、Cyclin D1表达水平增高,拮抗剂DDK1表达降低,拮抗作用减弱;而外源性上调mi RNA-21表达时,PASMCs中β-catenin、Cyclin D1表达水平降低,拮抗剂DDK1表达增高,拮抗作用增强。结论mi RNA-21的早期干预可通过调控Wnt通路的拮抗剂DKK1作用与Wnt/β-catenin信号通路参与PH肺血管重构。

谈与“菌”相关的“肠”识——以肠菌视野初探间歇性禁食

间歇性禁食(IF)能够治疗疾病,促进机体健康。近年来研究发现,肠道菌群在IF治疗疾病中发挥着重要的介导作用。本文对IF是如何通过重塑肠道菌群来治疗疾病进行了详细的探讨,并对IF及肠道菌群治疗疾病的潜力提出了自己的见解,希望能够给读者提供新的思路及方法。

“辟谷-服气-服药”三联法治疗脊髓损伤及并发症的理论初探

辟谷是中国古代养生术的一种,它指的是通过服药、服气等方法达到节制食量、辟谷清肠的目的。首先,辟谷不仅可以抑制炎性反应,控制感染;也有神经保护作用,促进神经重建、肢体恢复,其对SCI及其并发症有良好的调控作用。其次,通过多历代辟谷方药的研究,发现大量辟谷辅助药饵的功效与SCI的治则吻合,其一可补气而令人不思食;二可通过药物通阳活血,补肾填精,直指病机。第三,服气法不仅通过服气吐纳,通调气机,增强肺通气;其"开合毛孔""以意驭气"所暗涵的运动想象疗法也是治疗SCI及并发症的一大利器。总之,辟谷三联法对脊髓损伤及并发症,提供新的思路及方法,值得继续研习。

IκB激酶β在脊髓损伤后炎症反应机制中作用的研究进展

IκB激酶β(IKKβ)是核因子κB(NF-κB)信号通路中的关键激酶。在脊髓损伤后,IKKβ被活化,NF-κB信号通路异常激活,产生大量炎症因子,对脊髓损伤后的恢复产生不利影响。本文主要对IKKβ的结构功能及其在脊髓损伤后炎症反应中的应用进行综述,试图寻找一种治疗脊髓损伤的新靶点。