Patients with age-related hearing loss face hearing difficulties in daily life.The causes of age-related hearing loss are complex and include changes in peripheral hearing,central processing,and cognitive-related abil...Patients with age-related hearing loss face hearing difficulties in daily life.The causes of age-related hearing loss are complex and include changes in peripheral hearing,central processing,and cognitive-related abilities.Furthermore,the factors by which aging relates to hearing loss via changes in audito ry processing ability are still unclear.In this cross-sectional study,we evaluated 27 older adults(over 60 years old) with age-related hearing loss,21 older adults(over 60years old) with normal hearing,and 30 younger subjects(18-30 years old) with normal hearing.We used the outcome of the uppe r-threshold test,including the time-compressed thres h old and the speech recognition threshold in noisy conditions,as a behavioral indicator of auditory processing ability.We also used electroencephalogra p hy to identify presbycusis-related abnormalities in the brain while the participants were in a spontaneous resting state.The timecompressed threshold and speech recognition threshold data indicated significant diffe rences among the groups.In patients with age-related hearing loss,information masking(babble noise) had a greater effect than energy masking(speech-shaped noise) on processing difficulties.In terms of resting-state electroencephalography signals,we observed enhanced fro ntal lobe(Brodmann’s area,BA11) activation in the older adults with normal hearing compared with the younger participants with normal hearing,and greater activation in the parietal(BA7) and occipital(BA19) lobes in the individuals with age-related hearing loss compared with the younger adults.Our functional connection analysis suggested that compared with younger people,the older adults with normal hearing exhibited enhanced connections among networks,including the default mode network,sensorimotor network,cingulo-opercular network,occipital network,and frontoparietal network.These results suggest that both normal aging and the development of age-related hearing loss have a negative effect on advanced audito ry processing capabilities and that hearing loss accele rates the decline in speech comprehension,especially in speech competition situations.Older adults with normal hearing may have increased compensatory attentional resource recruitment represented by the to p-down active listening mechanism,while those with age-related hearing loss exhibit decompensation of network connections involving multisensory integration.展开更多
We investigated migration of pollutant at the base of the Suzhou landfill after it had been operated for 13 years. The investigation was carried out by performing chemical analyses on the soil samples taken from the s...We investigated migration of pollutant at the base of the Suzhou landfill after it had been operated for 13 years. The investigation was carried out by performing chemical analyses on the soil samples taken from the silty clay deposit. Concentrations of chloride, chemical oxygen demand (COD) and the heavy metals in the soil samples were determined using the standard methods. The experimental data showed that the maximum migration depth of chloride was more than 10 m, while the maximum migration depth of COD varied between 1 and 3.5 m. It is believed that the difference is attributed to the variation in diffusion rate and leachate-soil interaction. The chloride profiles also indicated that adveetion may be the dominant contaminant transport mechanism at this site. The total contents ofCu, Pb and Cr are very close to the background levels and the concentration values of these metals mainly are lower than the threshold values specified by the Chinese soil quality standard and the European one. The water-extractable concentrations of COD in the surface of the silty clay generally exceed the limit value specified by the Chinese standard. The concentrations of copper and chromium in pore water are 1-2 orders of magnitude less than the total concentrations of these heavy metals within the soils, implying that heavy metals are mainly adsorbed by the soil particles. Finally, remediation methods were suggested for this landfill site.展开更多
When tunnels are constructed in coastal cities,they will inevitably undercross a river.Exploring the influence of rivers on tunnelling-induced deformation in costal soft soil is of great significance for controlling e...When tunnels are constructed in coastal cities,they will inevitably undercross a river.Exploring the influence of rivers on tunnelling-induced deformation in costal soft soil is of great significance for controlling excessive settlement and protecting surrounding buildings.This paper presents a case study of twin tunnels undercrossing a river in soft soil in Hangzhou,China.The soft soil of Hangzhou refers to cohesive soil in a soft plastic or fluid plastic state with high natural water content,high compressibility,low bearing capacity,and low shear strength.Considering the influence of the river,the research region was divided into two parts,inside and outside the river-affected area,based on monitoring data of the Zizhi Tunnel.The development law of surface settlement is divided into three stages.In the first and second stages,the surface settlement within and outside the river-affected area showed a similar trend:the settlement increased and the growth rate of settlement in the second stage was smaller within the river-affected area.In the third stage,the surface settlement continued to increase within the river-affected area,while it converged outside the river-affected area.Within the river-affected area,there was an asynchronization of the sinking rate and stability of vault settlements and surface settlements.A numerical model was established by simulating different reinforcements of the tunnel.The numerical model revealed that the ground movement is influenced by the distribution and amount of the excess pore water pressure.The excess pore pressure was concentrated mostly in the range of 1.0H_(t)-3.0H_(t)(H_(t) is the tunnel height)before the tunnel face,especially within the river-affected area.Inside the river-affected area,the dissipation of excess pore water pressure needs more time,leading to slow stabilization of surface settlement.When undercrossing a river,a cofferdam is necessary to reduce excessive ground deformation by dispersing the distribution of excess pore water pressure.展开更多
In this study,we propose a drainage pipe pile under vacuum consolidation to integrate foundation treatment and pile foundation engineering in soft soil areas.To study its bearing capacity characteristics and foundatio...In this study,we propose a drainage pipe pile under vacuum consolidation to integrate foundation treatment and pile foundation engineering in soft soil areas.To study its bearing capacity characteristics and foundation treatment performance,single pile static load tests,vane shear tests,and water content tests were carried out for ordinary piles,perforated piles,and drainage pipe piles under conditions of static and vacuum consolidation.Based on the results,the concept of strong and weak reinforcement areas was proposed and used for bearing capacity prediction.The results showed that the drainage pipe pile did not become silted under vacuum consolidation.The single pile bearing capacity was much higher than that of an ordinary pile,and the pile side friction was exerted mainly in the middle and lower parts.Good results were achieved using the shear strength at the junction of the strong and weak reinforcement areas to estimate the ultimate bearing capacity of a single pile.This study provided important insights into the design and construction of drainage pipe piles in a soft soil foundation.展开更多
基金supported by the National Natural Science Foundation of China,Nos.82171138 (to YQZ),82071 062 (to YXC)the Natural Science Foundation of Guangdong Province,No.2021A1515012038 (to YXC)+1 种基金the Fundamental Research Funds for the Central Universities,No.20ykpy91 (to YXC)the Sun Yat-Sen Clinical Research Cultivating Program,No.SYS-Q-201903 (to YXC)。
文摘Patients with age-related hearing loss face hearing difficulties in daily life.The causes of age-related hearing loss are complex and include changes in peripheral hearing,central processing,and cognitive-related abilities.Furthermore,the factors by which aging relates to hearing loss via changes in audito ry processing ability are still unclear.In this cross-sectional study,we evaluated 27 older adults(over 60 years old) with age-related hearing loss,21 older adults(over 60years old) with normal hearing,and 30 younger subjects(18-30 years old) with normal hearing.We used the outcome of the uppe r-threshold test,including the time-compressed thres h old and the speech recognition threshold in noisy conditions,as a behavioral indicator of auditory processing ability.We also used electroencephalogra p hy to identify presbycusis-related abnormalities in the brain while the participants were in a spontaneous resting state.The timecompressed threshold and speech recognition threshold data indicated significant diffe rences among the groups.In patients with age-related hearing loss,information masking(babble noise) had a greater effect than energy masking(speech-shaped noise) on processing difficulties.In terms of resting-state electroencephalography signals,we observed enhanced fro ntal lobe(Brodmann’s area,BA11) activation in the older adults with normal hearing compared with the younger participants with normal hearing,and greater activation in the parietal(BA7) and occipital(BA19) lobes in the individuals with age-related hearing loss compared with the younger adults.Our functional connection analysis suggested that compared with younger people,the older adults with normal hearing exhibited enhanced connections among networks,including the default mode network,sensorimotor network,cingulo-opercular network,occipital network,and frontoparietal network.These results suggest that both normal aging and the development of age-related hearing loss have a negative effect on advanced audito ry processing capabilities and that hearing loss accele rates the decline in speech comprehension,especially in speech competition situations.Older adults with normal hearing may have increased compensatory attentional resource recruitment represented by the to p-down active listening mechanism,while those with age-related hearing loss exhibit decompensation of network connections involving multisensory integration.
基金supported by the National Natural Science Foundation of China (No. 50538080)the National Science Fund for Distinguished Young Scholars (No. 50425825), China
文摘We investigated migration of pollutant at the base of the Suzhou landfill after it had been operated for 13 years. The investigation was carried out by performing chemical analyses on the soil samples taken from the silty clay deposit. Concentrations of chloride, chemical oxygen demand (COD) and the heavy metals in the soil samples were determined using the standard methods. The experimental data showed that the maximum migration depth of chloride was more than 10 m, while the maximum migration depth of COD varied between 1 and 3.5 m. It is believed that the difference is attributed to the variation in diffusion rate and leachate-soil interaction. The chloride profiles also indicated that adveetion may be the dominant contaminant transport mechanism at this site. The total contents ofCu, Pb and Cr are very close to the background levels and the concentration values of these metals mainly are lower than the threshold values specified by the Chinese soil quality standard and the European one. The water-extractable concentrations of COD in the surface of the silty clay generally exceed the limit value specified by the Chinese standard. The concentrations of copper and chromium in pore water are 1-2 orders of magnitude less than the total concentrations of these heavy metals within the soils, implying that heavy metals are mainly adsorbed by the soil particles. Finally, remediation methods were suggested for this landfill site.
基金supported by the National Natural Science Foundation of China(No.51508503)the Major Research Plan of National Natural Science Foundation of China(No.51338009)the Research Plan of the Academician Workstation of Guangzhou Chemical Grouting Co.Ltd.,China Academy of Science(No.2016GZZ01)
基金Project supported by the National Natural Science Foundation of China(No.51508503)the Fund of the China Scholarship Council(No.201406320025)the Research Plan of the Academician Workstation of Guangzhou Chemical Grouting Co.Ltd.,China Academy of Science(No.2016GZZ01)
基金This work is supported by the Key Water Science and Technology Project of Zhejiang Province(No.RB2027)the Zhejiang Province Public Welfare Technology Application Research Project(No.LGG22E080002),China.
文摘When tunnels are constructed in coastal cities,they will inevitably undercross a river.Exploring the influence of rivers on tunnelling-induced deformation in costal soft soil is of great significance for controlling excessive settlement and protecting surrounding buildings.This paper presents a case study of twin tunnels undercrossing a river in soft soil in Hangzhou,China.The soft soil of Hangzhou refers to cohesive soil in a soft plastic or fluid plastic state with high natural water content,high compressibility,low bearing capacity,and low shear strength.Considering the influence of the river,the research region was divided into two parts,inside and outside the river-affected area,based on monitoring data of the Zizhi Tunnel.The development law of surface settlement is divided into three stages.In the first and second stages,the surface settlement within and outside the river-affected area showed a similar trend:the settlement increased and the growth rate of settlement in the second stage was smaller within the river-affected area.In the third stage,the surface settlement continued to increase within the river-affected area,while it converged outside the river-affected area.Within the river-affected area,there was an asynchronization of the sinking rate and stability of vault settlements and surface settlements.A numerical model was established by simulating different reinforcements of the tunnel.The numerical model revealed that the ground movement is influenced by the distribution and amount of the excess pore water pressure.The excess pore pressure was concentrated mostly in the range of 1.0H_(t)-3.0H_(t)(H_(t) is the tunnel height)before the tunnel face,especially within the river-affected area.Inside the river-affected area,the dissipation of excess pore water pressure needs more time,leading to slow stabilization of surface settlement.When undercrossing a river,a cofferdam is necessary to reduce excessive ground deformation by dispersing the distribution of excess pore water pressure.
基金supported by the Key Water Science and Technology Project of Zhejiang Province(No.RB2027)the Zhejiang Provincial Public Welfare Technology Application Research Project(No.LGG22E080002),China。
文摘In this study,we propose a drainage pipe pile under vacuum consolidation to integrate foundation treatment and pile foundation engineering in soft soil areas.To study its bearing capacity characteristics and foundation treatment performance,single pile static load tests,vane shear tests,and water content tests were carried out for ordinary piles,perforated piles,and drainage pipe piles under conditions of static and vacuum consolidation.Based on the results,the concept of strong and weak reinforcement areas was proposed and used for bearing capacity prediction.The results showed that the drainage pipe pile did not become silted under vacuum consolidation.The single pile bearing capacity was much higher than that of an ordinary pile,and the pile side friction was exerted mainly in the middle and lower parts.Good results were achieved using the shear strength at the junction of the strong and weak reinforcement areas to estimate the ultimate bearing capacity of a single pile.This study provided important insights into the design and construction of drainage pipe piles in a soft soil foundation.