BACKGROUND Despite sharing similar pathogenic factors,cancer and coronary heart disease(CHD)occur in comparable populations at similar ages and possess similar susceptibility factors.Consequently,it is increasingly co...BACKGROUND Despite sharing similar pathogenic factors,cancer and coronary heart disease(CHD)occur in comparable populations at similar ages and possess similar susceptibility factors.Consequently,it is increasingly commonplace for patients to experience the simultaneous occurrence of cancer and CHD,a trend that is steadily rising.AIM To determine the impacts of continuing care on lung cancer patients with CHD following percutaneous coronary intervention(PCI).METHODS There were 94 lung cancer patients with CHD following PCI who were randomly assigned to the intervention group(n=38)and the control group(n=41).In the intervention group,continuing care was provided,while in the control group,routine care was provided.An evaluation of cardiac and pulmonary function,medication compliance,a 6-min walk test,and patient quality of life was performed.RESULTS Differences between the two groups were significant in left ventricular ejection fraction,6-min walk test,oxygen uptake,quality of life and medication compliance(P<0.05).In comparison with the control group,the enhancement in the intervention group was more significant.The intervention group had more patients with high medication compliance than the control group,with a statistically significant difference(P<0.05).CONCLUSION After undergoing PCI,lung patients with CHD could benefit from continued care in terms of cardiac and pulmonary function,medications compliance,and quality of life.展开更多
Biphenyl-contained monomer of 1,4-bis[2-(3,4-epoxy cyclohexyl ethyl) dimethylsilyl] biphenyl (BP-SiH-EP) was prepared via hydrosilylation reaction of 1,4-bis(dimethylsilyl) biphenyl (BP-SiH) and 1,2-epoxy-4-vi...Biphenyl-contained monomer of 1,4-bis[2-(3,4-epoxy cyclohexyl ethyl) dimethylsilyl] biphenyl (BP-SiH-EP) was prepared via hydrosilylation reaction of 1,4-bis(dimethylsilyl) biphenyl (BP-SiH) and 1,2-epoxy-4-vinylcyclohexane in the presence of Karstedt's catalyst. ^1H-NMR, 13C-NMR and FTIR were used to characterize the structure of the obtained monomer. BP-SiH-EP was then cured by methyl hexahydrophthalic anhydride (MeHHPA) with 1-cyanoethyl-2-ethyl-4- methylimidazole as an accelerator. The polymerization behavior was studied by DSC. The results of DMA measurement demonstrate that the cured BP-SiH-EP/MeHHPA can maintain high storage modulus (〉1 GPa) in a wide range of temperature up to 176 ℃. According to the damping factor curve of DMA, cured BP-SiH-EP/MeHHPA exhibits a high glass transition temperature (Tg) of 192 ℃, which is 20 ℃ higher than that of cured 1,4-bis[2-(3,4-epoxy cyclohexyl ethyl) dimethylsilyl] benzene (DEDSB)/MeHHPA. TGA results show that cured BP-SiH-EP/MeHHPA has good thermal stability (Tso/o = 339 ℃) due to the high heat-resistance of rigid biphenyl group. Moreover, the crosslinking density of cured BP-SiH-EP/MeHHPA should be lower than that of cured DEDSB/MeHHPA estimated from their chemical structures, which conflicts with the calculated results based on the rubber elasticity equation. The inconsistence indicates that the calculated crosslinking densities are not comparable, possibly owing to their differences in the rigidity of polymer chains and intermolecular interaction.展开更多
文摘BACKGROUND Despite sharing similar pathogenic factors,cancer and coronary heart disease(CHD)occur in comparable populations at similar ages and possess similar susceptibility factors.Consequently,it is increasingly commonplace for patients to experience the simultaneous occurrence of cancer and CHD,a trend that is steadily rising.AIM To determine the impacts of continuing care on lung cancer patients with CHD following percutaneous coronary intervention(PCI).METHODS There were 94 lung cancer patients with CHD following PCI who were randomly assigned to the intervention group(n=38)and the control group(n=41).In the intervention group,continuing care was provided,while in the control group,routine care was provided.An evaluation of cardiac and pulmonary function,medication compliance,a 6-min walk test,and patient quality of life was performed.RESULTS Differences between the two groups were significant in left ventricular ejection fraction,6-min walk test,oxygen uptake,quality of life and medication compliance(P<0.05).In comparison with the control group,the enhancement in the intervention group was more significant.The intervention group had more patients with high medication compliance than the control group,with a statistically significant difference(P<0.05).CONCLUSION After undergoing PCI,lung patients with CHD could benefit from continued care in terms of cardiac and pulmonary function,medications compliance,and quality of life.
基金financially supported by the National Natural Science Foundation of China(Nos.51403039 and 21476072)the Natural Science Foundation of Shanghai(No.13ZR1451300)
文摘Biphenyl-contained monomer of 1,4-bis[2-(3,4-epoxy cyclohexyl ethyl) dimethylsilyl] biphenyl (BP-SiH-EP) was prepared via hydrosilylation reaction of 1,4-bis(dimethylsilyl) biphenyl (BP-SiH) and 1,2-epoxy-4-vinylcyclohexane in the presence of Karstedt's catalyst. ^1H-NMR, 13C-NMR and FTIR were used to characterize the structure of the obtained monomer. BP-SiH-EP was then cured by methyl hexahydrophthalic anhydride (MeHHPA) with 1-cyanoethyl-2-ethyl-4- methylimidazole as an accelerator. The polymerization behavior was studied by DSC. The results of DMA measurement demonstrate that the cured BP-SiH-EP/MeHHPA can maintain high storage modulus (〉1 GPa) in a wide range of temperature up to 176 ℃. According to the damping factor curve of DMA, cured BP-SiH-EP/MeHHPA exhibits a high glass transition temperature (Tg) of 192 ℃, which is 20 ℃ higher than that of cured 1,4-bis[2-(3,4-epoxy cyclohexyl ethyl) dimethylsilyl] benzene (DEDSB)/MeHHPA. TGA results show that cured BP-SiH-EP/MeHHPA has good thermal stability (Tso/o = 339 ℃) due to the high heat-resistance of rigid biphenyl group. Moreover, the crosslinking density of cured BP-SiH-EP/MeHHPA should be lower than that of cured DEDSB/MeHHPA estimated from their chemical structures, which conflicts with the calculated results based on the rubber elasticity equation. The inconsistence indicates that the calculated crosslinking densities are not comparable, possibly owing to their differences in the rigidity of polymer chains and intermolecular interaction.