Stability analysis of unsaturated soil slope during rainfall infiltration using coupled liquid-gas-solid three-phase model

Generally, most soil slope failures are induced by rainfall infiltration, a process that involves interactions between the liquid phase, gas phase,and solid skeleton in an unsaturated soil slope. In this study, a loosely coupled liquid-gas-solid three-phase model, linking two numerical codes,TOUGH2/EOS3, which is used for water-air two-phase flow analysis, and FLAC^(3D), which is used for mechanical analysis, was established. The model was validated through a documented water drainage experiment over a sandy column and a comparison of the results with measured data and simulated results from other researchers. The proposed model was used to investigate the features of water-air two-phase flow and stress fields in an unsaturated soil slope during rainfall infiltration. The slope stability analysis was then performed based on the simulated water-air two-phase seepage and stress fields on a given slip surface. The results show that the safety factor for the given slip surface decreases first, then increases, and later decreases until the rainfall stops. Subsequently, a sudden rise occurs. After that, the safety factor decreases continually and reaches its lowest value, and then increases slowly to a steady value. The lowest value does not occur when the rainfall stops, indicating a delayed effect of the safety factor. The variations of the safety factor for the given slip surface are therefore caused by a combination of pore-air pressure, matric suction, normal stress, and net normal stress.

Total splenic artery embolization for splenic artery aneurysms in patients with normal spleen

AIM: To evaluate total embolization of the main splenic artery in patients with splenic artery aneurysms (SAAs) and normal spleen.

Performance of n-type silicon/silver composite anode material in lithium ion batteries: A study on effect of work function matching degree

In this paper, two types of silicon（Si） particles ball-milled from n-type Si wafers, respectively, with resistivity values of 1 Ω·cm and 0.001 Ω·cm are deposited with silver（Ag）. The Ag-deposited n-type 1-Ω·cm Si particles（nl-Ag） and Ag-deposited n-type 0.001-Ω·cm Si particles（n0.001-Ag） are separately used as an anode material to assemble coin cells,of which the electrochemical performances are investigated. For the matching of work function between n-type 1-Ω·cm Si（nl） and Ag, nl-Ag shows discharge specific capacity of up to 683 mAh·g^-1 at a current density of 8.4 A·g^-1, which is40% higher than that of n0.001-Ag. Furthermore, the resistivity of nl-Ag is lower than half that of n0.001-Ag. Due to the mismatch of work function between n-type 0.001-Ω·cm Si（n0.001） and Ag, the discharge specific capacity of n0.001-Ag is 250.2 mAh·g^-1 lower than that of nl-Ag after 100 cycles.

The E3 ubiquitin ligase seven in absentia homolog 1 may be a potential new therapeutic target for Parkinson's disease

In this study, we investigated the effect of an antibody against E3 ubiquitin ligase seven in absentia homolog 1（SIAH-1） in PC12 cells. 1-Methyl-4-phenylpyridinium（MPP＋） treatment increased α-synuclein, E1 and SIAH-1 protein levels in PC12 cells, and it reduced cell viability; however, there was no significant change in light chain 3 expression. Treatment with an SIAH-1 antibody decreased m RNA expression levels of α-synuclein, light chain 3 and SIAH-1, but increased E1 m RNA expression. It also increased cell viability. Combined treatment with MPP＋ and rapamycin reduced SIAH-1 and α-synuclein levels. Treatment with SIAH-1 antibody alone diminished α-synuclein immunoreactivity in PC12 cells, and reduced the colocalization of α-synuclein and light chain 3. These findings suggest that the SIAH-1 antibody reduces the monoubiquitination and aggregation of α-synuclein, promoting its degradation by the ubiquitin-proteasome pathway. Consequently, SIAH-1 may be a potential new therapeutic target for Parkinson’s disease.

Aerodynamic Model Analysis and Flight Simulation Research of UAV Based on Simulink

Mathematical simulation method can be adopted to check flight characteristic of UAV, also can be adopted to simulate hardware experiments of unmanned aerial vehicle (UAV), then related flight experiments can be performed. The simulation method can reduce the flight periods, cost and risk. UAV flight model research play an important role in simulation and modeling in initialize periods of the UAV producing. The study of the paper focuses on the aerodynamic force modeling work of UAV based on Simulink. The designed model not only can afford mathematics simulation experiment but also will do benefits to the research of flight control, navigation guidance of UAV.

消化道恶性肿瘤患者团体心理疗法的效果观察

目的观察心理筛查指导下团体疗法对消化道恶性肿瘤患者的焦虑情绪、抑郁情绪及自尊水平的影响。方法将该院近期收治的62例消化道恶性肿瘤心理状况不良患者按随机数字法等分为个体疗法组(n=31)和团体疗法组(n=31),个体疗法组以个体形式对患者进行心理干预治疗3周,团体疗法组以团体形式对患者进行心理干预治疗3周,比较两组患者治疗后焦虑情绪、抑郁情绪改善效果及自尊水平改善效果。结果两组患者治疗后焦虑自评量表得分、抑郁自评得分均有所降低,且团体疗法组患者治疗后的焦虑自评量表得分和抑郁自评得分均低于个体疗法组(P<0.05)。两组患者治疗后自尊自评量表得分均有所提升,且团体疗法组患者治疗后的自尊自评量表得分高于个体疗法组(P<0.05)。团体疗法组治疗总有效率高于个体疗法组(P<0.05)。结论心理筛查指导下的团体疗法对消化道恶性肿瘤患者的焦虑情绪、抑郁情绪改善效果优于个体疗法,且对患者自尊心的提升效果也优于个体疗法,是一种理想的消化道恶性肿瘤患者心理干预治疗方案,值得临床推广。

The absorbing properties of Fe_(73.5) Cu_1 Nb_3Si_(13.5)B_9 amorphous powder/S-glass fiber-reinforced epoxy composite panels

Fe73.5Cu1Nb3Si13.5B9 （or FeCuNbSiB） powder/ S-glass fiber-reinforced epoxy composite panels were pre- pared by mold pressing method. Metallographic analysis shows that the amorphous powders are evenly distributed between the layers of S-glass fibers. The effects of the Fe- CuNbSiB powder mass fraction on the complex permittivity, complex permeability, and microwave absorption of the composite panels have been studied in the frequency range of 2.6-18.0 GHz. The complex permittivity of the composite panels with different mass fractions of the FeCuNbSiB powders shows several peaks in the 2.6-18.0 GHz fre- quency range. The complex permeability of the composites decreases with the increasing frequency in the frequency range of 8-18 GHz. The composite with FeCuNbSiB/epoxy mass ratio of 2.5：1.0 has excellent microwave absorption properties of a minimum reflection loss value -30.5 dB at 10.93 GHz for a thickness of 2 mm. A reflection loss exceeding -10 dB can be obtained in a broad frequency range of 3.2-18.0 GHz with a thickness of 1.15-5.00 mm. For the FeCuNbSiB composites, the magnetic loss is the dominant term for microwave absorption. The FeCuNbSiB powders are a possible candidate for high-performance microwave absorption filler.

Eff ects of early standardized enteral nutrition on preventing acute muscle loss in the acute exacerbation of chronic obstructive pulmonary disease patients with mechanical ventilation

BACKGROUND:To investigate the eff ects of early standardized enteral nutrition(EN)on the crosssectional area of erector spine muscle(ESMcsa),plasma growth diff erentiation factor-15(GDF-15),and 28-day mortality of acute exacerbation of chronic obstructive pulmonary disease(AECOPD)patients with invasive mechanical ventilation(MV).METHODS:A total of 97 AECOPD patients with invasive MV were screened in the ICUs of the First People's Hospital of Lianyungang.The conventional EN group(stage Ⅰ)and early standardized EN group(stage Ⅱ)included 46 and 51 patients,respectively.ESMcsa loss and GDF-15 levels on days 1 and 7 of ICU admission and 28-day survival rates were analyzed.RESULTS:On day 7,the ESMcsa of the early standardized EN group was significantly higher than that of the conventional EN group,while the plasma GDF-15 levels were significantly lower than those in the conventional EN group(ESMcsa:28.426±6.130 cm^(2) vs.25.205±6.127 cm^(2);GDF-15:1661.608±558.820 pg/mL vs.2541.000±634.845 pg/mL;all P<0.001).The 28-day survival rates of the patients in the early standardized EN group and conventional EN group were 80.40%and 73.90%,respectively(P=0.406).CONCLUSION:ESMcsa loss in AECOPD patients with MV was correlated with GDF-15 levels,both of which indicated acute muscular atrophy and skeletal muscle dysfunction.Early standardized EN may prevent acute muscle loss and intensive care unit-acquired weakness(ICU-AW)in AECOPD patients.

Preparation and application in electromagnetic absorption of ZnO/FeNiMo composite

In order to increase the absorbing ability and expand the absorbing bandwidth, ZnO and FeNiMo particles were established as absorbers, and wax as adhesive, and the electromagnetic parameters were tested using a vector network analyzer, then the absorbing properties were calculated by means of transmission line theory. The ZnO/FeNiMo composite has excellent microwave absorption properties of a minimum reflection loss value-27.8 dB at 15.98 GHz for a thickness of 1.5 mm and a broad absorption bandwidth of 13.46–18 GHz（RL 〈-10 dB）.

Recent advances of metal-organic frameworks-based proton exchangemembranes in fuel cell applications

In recent years,proton exchange membrane(PEM)fuel cell(FC;PEMFC)has been widely studied and gradually applied to vehicle power supply,portable supply,communication base station backup,emergency power supply,and so on.Especially in new energy vehicles,PEMFC has absolute advantages and a broad market.PEM,which is the core component of PEMFC,has a close correlation between its property and the performance of FC.Therefore,developing excellent PEMs is the focus of researchers.Metal–organic frameworks(MOFs)composed of metal ions/clusters and organic ligands have attracted extensive attention in the field of proton conduction.The hybrid membranes formed by MOFs and polymers show excellent performances and design concepts,which have great prospects in commercial application.This paper summarizes the research progress of MOFs-based hybrid membranes as PEMs applied in hydrogen–oxygen FCs and direct methanol FCs,in which the different polymers used as substrates are also summed up.

Force-sensitive properties of FeCuNbSiB powder/silicone rubber composite films

Composite films of different contents were prepared by Fe73.5Cu1Nb3Si13.5B9 powder as compound phase and silicone rubber as matrix phase. The thickness of film is 200 μm. Values of impedance, Z, under pressure stress were measured by TH2816LCR digital bridge. LYYL-500N high-grade-type microcomputer control pressure testing machine was used to conduct program control loading with a speed of 0.1 mm·min^-1. The results show that composite films of different contents （25 vol%, 30 vol%, and 35 vol%） have excellent force-sensitive properties in both loading process and unloading process, especially when the stress is below 0.2 MPa, the stress- impedance （SI） and ＋｜k｜ values of composite films are much higher than that in the range of 0.2-1.0 MPa. The force- sensitive properties of loading process are superior to unloading process. While the frequency is 1 kHz, the force-sensitive properties of composite films are better than 50 kHz. The optimal temperature of powder heat treatment is 500 ℃. Composite film which was prepared by this kind of powder has a good force-sensitive property.

Microstructure and texture evolution during recrystallization of low-carbon steel sheets

Aluminum killed low-carbon steel sheets were cold rolled at different reduction ratios and annealed using different temperatures and holding time.The Vickers hardness was examined.The results show that when cold rolling reduction ratios increase from 40% to 81%,recrystallization temperatures decrease from 602℃ to 572℃ during 4hisochronal annealing,as well recrystallization holding time decreases from 117 min to 5min during isothermal annealing at 610℃.All recrystallization temperatures and holding time can be calculated using the annealing experiment results.Microstructure was examined through electron backscattered diffraction（EBSD）.The results show that as rolling direction preferentially grows,equiaxed grains grow into cake-type during recrystallization.Cake-type grains are more beneficial to obtaining ideal〈111〉//ND（normal direcrtion）orientation texture.{111}orientation grains nucleate and grow up preferentially.Deformation grains of{111}〈110〉orientations grow into new recrystallization grains of{111}〈123〉and{111}〈112〉during recrystallization.Texture formation can be explained by directional nucleation.

Construction of biomimetic proton transport channels in metal-organic framework

Construction of proton transport channels in metal-organic frameworks(MOFs)with simple synthesis processes,high proton conductivities and good performance stabilities has been of great interest for proton exchange membrane fuel cell(PEMFC).Herein,we mimic the proton transport behavior of amino acid residues in bacteriorhodopsin,select UiO-66-COOH as the host,glycine and aspartic acid as the functional guest molecules,and then functionalize the MOF framework with amino acids to obtain biomimetic proton transport channels.This strategy endows UiO-66-COOH-Asp a high proton conductivity of 1.19×10^(-2)S/cm at 70℃and 98%RH,excellent cycle stability of performances and performance durability,which can be comparable to the reported MOFs-based proton conductors.Moreover,the proton conduction mechanism in UiO-66-COOH-Asp is elaborated in detail due to its visual structure,which is also one of the advantages of adopting MOFs as research platform,making it possible to optimize the structure-activity relationship of advanced materials.Notably,this strategy has clear objectives and simple synthesis,which has made certain contributions to both theoretical research and future industrial production of proton conductors.

Study on the safety and excellent probiotic properties of fermentation strains isolated from traditional dry-cured duck for starter development

The indigenous starter cultures isolated from fermented food can compete with spoilage and pathogenic bacteria and improve the flavor and organoleptic properties of products.The purposes of this work were to screen and assess the safety,potential probiotic,and fermentation properties of indigenous starter cultures isolated from dry-cured ducks.The properties of indigenous starter cultures were investigated by antibiotic resistance,virulence genes,in vivo toxicity,simulated gastrointestinal,adhesion capacity to Caco-2 cells,inoculation fermentation,etc.Overall,six strains were isolated and identified,including Lactobacillus sakei D15,Weissella hellenica D20,Lactobacillus curvatus D2,Staphylococcus simulans D12,Staphylococcus equorum D19,and Staphylococcus edaphicus D17.The obtained strains showed high safety.Additionally,most strains displayed excellent probiotic properties,including tolerance to lower pH,lysozyme,bile salt,and a high survival rate of the simulated gastrointestinal phase.The adhesion ability of strain cells to Caco-2 cells was 9.22%-14.21%.And the probiotic properties of strains can be strengthened by the expression of specific enzymes.The inoculation with the isolated strains(LS-D15,LC-D2 and SS-D12)could contribute to the formation of volatile flavor compounds in samples.Overall,results demonstrated that strains possessed excellent safety and probiotic properties,and can be used as starter cultures to enhance the quality and flavor of the dry-cured duck.

Manganese removal from the Qiantang River source water by pre-oxidation:A case study

We evaluated several different pre-oxidation treatments, namely the introduction of either potassium permanganate (KMnO4), chlorine (Cl2), or both to remove manganese (Mn) from the Qiantang River source water. Our results showed that Mn removal percentages were 12.7%, 71.0%, 17.4% and 58.7% when none of the oxidants, KMnO4 only, Cl2 only, or both oxidants were added, respectively. Furthermore, a field study showed that when the available Mn concentration in the source water was 0.14 mg/L, it could be reduced to less than 0.05 mg/L when a solution of KMnO4 (0.47 mg/L) was added as the oxidant.