As the world transitions to green energy, there is a growing focus among many researchers on the requirement for high-efficient and safe batteries. Solid-state lithium metal batteries(SSLMBs) have emerged as a promisi...As the world transitions to green energy, there is a growing focus among many researchers on the requirement for high-efficient and safe batteries. Solid-state lithium metal batteries(SSLMBs) have emerged as a promising alternative to traditional liquid lithium-ion batteries(LIBs), offering higher energy density, enhanced safety, and longer lifespan. The rise of SSLMBs has brought about a transformation in energy storage, with aluminum(Al)-based material dopants playing a crucial role in advancing the next generation of batteries. The review highlights the significance of Al-based material dopants in SSLMBs applications, particularly its contributions to solid-state electrolytes(SSEs), cathodes, anodes,and other components of SSLMBs. Some studies have also shown that Al-based material dopants effectively enhance SSE ion conductivity, stabilize electrode and SSE interfaces, and suppress lithium dendrite growth, thereby enhancing the electrochemical performance of SSLMBs. Despite the above mentioned progresses, there are still problems and challenges need to be addressed. The review offers a comprehensive insight into the important role of Al in SSLMBs and addresses some of the issues related to its applications, endowing valuable support for the practical implementation of SSLMBs.展开更多
Lithium-sulfur battery(LSB)has brought much attention and concern because of high theoretical specific capacity and energy density as one of main competitors for next-generation energy storage systems.The widely comme...Lithium-sulfur battery(LSB)has brought much attention and concern because of high theoretical specific capacity and energy density as one of main competitors for next-generation energy storage systems.The widely commercial application and development of LSB is mainly hindered by serious“shuttle effect”of lithium polysulfides(Li PSs),slow reaction kinetics,notorious lithium dendrites,etc.In various structures of LSB materials,array structured materials,possessing the composition of ordered micro units with the same or similar characteristics of each unit,present excellent application potential for various secondary cells due to some merits such as immobilization of active substances,high specific surface area,appropriate pore sizes,easy modification of functional material surface,accommodated huge volume change,enough facilitated transportation for electrons/lithium ions,and special functional groups strongly adsorbing Li PSs.Thus many novel array structured materials are applied to battery for tackling thorny problems mentioned above.In this review,recent progresses and developments on array structured materials applied in LSBs including preparation ways,collaborative structural designs based on array structures,and action mechanism analyses in improving electrochemical performance and safety are summarized.Meanwhile,we also have detailed discussion for array structured materials in LSBs and constructed the structure-function relationships between array structured materials and battery performances.Lastly,some directions and prospects about preparation ways,functional modifications,and practical applications of array structured materials in LSBs are generalized.We hope the review can attract more researchers'attention and bring more studying on array structured materials for other secondary batteries including LSB.展开更多
The liver is the central organ for digestion and detoxification and has unique metabolic and regenerative capacities.The hepatobiliary system originates from the foregut endoderm,in which cells undergo multiple events...The liver is the central organ for digestion and detoxification and has unique metabolic and regenerative capacities.The hepatobiliary system originates from the foregut endoderm,in which cells undergo multiple events of cell proliferation,migration,and differentiation to form the liver parenchyma and ductal system under the hierarchical regulation of transcription factors.Studies on liver development and diseases have revealed that SRY-related high-mobility group box 9(SOx9)plays an important role in liver embryogenesis and the progression of hepatobiliary diseases.sox9 is not only a master regulator of cell fate determination and tissue morphogenesis,but also regulates various biological features of cancer,including cancer stemness,invasion,and drug resistance,making Sox9 a potential biomarker for tumor prognosis and progression.This review systematically summarizes the latest findings of sox9 in hepatobiliary development,homeostasis,and disease.We also highlight the value of sox9 as a novel biomarker and potential target for the clinical treatment of major liverdiseases.展开更多
The objective of this study was to develop an effective,potential wound dressing,which was constructed with a composite hydrogel of poly(vinyl alcohol)(PVA),carboxymethyl chitosan(CMC)and tannic acid(TA)by cryogenic t...The objective of this study was to develop an effective,potential wound dressing,which was constructed with a composite hydrogel of poly(vinyl alcohol)(PVA),carboxymethyl chitosan(CMC)and tannic acid(TA)by cryogenic treatment and freeze-drying method.The as-prepared TA-crosslinked PVA/CMC hydrogels exhibited interconnected pore structure with the mean pore size of roughly 3.7𝜇m.We found that the compressive strength and stiffness of composite hydrogel increased when the TA component was introduced.However,the PVA/CMC-TA hydrogel possessed obviously lower swell property than that of the TA-free PVA/CMC hydrogel.We also found that the TA addition significantly improved the antibacterial capacity of the as-prepared hydrogel.Moreover,the inhibition zone test showed that the antibacterial activity of PVA/CMC-TA against S.aureus bacteria was greater than that against E.coli.The biological results indicated that the PVA/CMC-TA hydrogel exhibited good cytocompatibility to natural human dermal fibroblasts.In summary,our PVA/CMC-TA composite hydrogel exhibited promising mechanical and antibacterial properties,which showed great potential application as wound healing materials.展开更多
基金Tianjin Natural Science Foundation (23JCYBJC00660)Tianjin Enterprise Science and Technology Commissioner Project (23YDTPJC00490)+4 种基金National Natural Science Foundation of China (52203066, 51973157, 61904123)China Postdoctoral Science Foundation Grant (2023M742135)National innovation and entrepreneurship training program for college students (202310058007)Tianjin Municipal college students’ innovation and entrepreneurship training program (202310058088)State Key Laboratory of Membrane and Membrane Separation, Tiangong University。
文摘As the world transitions to green energy, there is a growing focus among many researchers on the requirement for high-efficient and safe batteries. Solid-state lithium metal batteries(SSLMBs) have emerged as a promising alternative to traditional liquid lithium-ion batteries(LIBs), offering higher energy density, enhanced safety, and longer lifespan. The rise of SSLMBs has brought about a transformation in energy storage, with aluminum(Al)-based material dopants playing a crucial role in advancing the next generation of batteries. The review highlights the significance of Al-based material dopants in SSLMBs applications, particularly its contributions to solid-state electrolytes(SSEs), cathodes, anodes,and other components of SSLMBs. Some studies have also shown that Al-based material dopants effectively enhance SSE ion conductivity, stabilize electrode and SSE interfaces, and suppress lithium dendrite growth, thereby enhancing the electrochemical performance of SSLMBs. Despite the above mentioned progresses, there are still problems and challenges need to be addressed. The review offers a comprehensive insight into the important role of Al in SSLMBs and addresses some of the issues related to its applications, endowing valuable support for the practical implementation of SSLMBs.
基金This work was supported by the National Natural Science Foundation of China(52203066,51973157,61904123)the Tianjin Natural Science Foundation(18JCQNJC02900)+3 种基金the National innovation and entrepreneurship training program for college students(202310058007)the Tianjin Municipal college students’innovation and entrepreneurship training program(202310058088)the Science&Technology Development Fund of Tianjin Education Commission for Higher Education(Grant No.2018KJ196)the State Key Laboratory of Membrane and Membrane Separation,Tiangong University.
文摘Lithium-sulfur battery(LSB)has brought much attention and concern because of high theoretical specific capacity and energy density as one of main competitors for next-generation energy storage systems.The widely commercial application and development of LSB is mainly hindered by serious“shuttle effect”of lithium polysulfides(Li PSs),slow reaction kinetics,notorious lithium dendrites,etc.In various structures of LSB materials,array structured materials,possessing the composition of ordered micro units with the same or similar characteristics of each unit,present excellent application potential for various secondary cells due to some merits such as immobilization of active substances,high specific surface area,appropriate pore sizes,easy modification of functional material surface,accommodated huge volume change,enough facilitated transportation for electrons/lithium ions,and special functional groups strongly adsorbing Li PSs.Thus many novel array structured materials are applied to battery for tackling thorny problems mentioned above.In this review,recent progresses and developments on array structured materials applied in LSBs including preparation ways,collaborative structural designs based on array structures,and action mechanism analyses in improving electrochemical performance and safety are summarized.Meanwhile,we also have detailed discussion for array structured materials in LSBs and constructed the structure-function relationships between array structured materials and battery performances.Lastly,some directions and prospects about preparation ways,functional modifications,and practical applications of array structured materials in LSBs are generalized.We hope the review can attract more researchers'attention and bring more studying on array structured materials for other secondary batteries including LSB.
基金supported by grants from the National Natural Science Foundation of China(No.82172895,81670516)the Funds for CreativeResearch Groups of China(No.81521091)the Clinical Research Plan of Shanghai Hospital Development Center(SHDC,China)(No.SHDC2020CR2011A).
文摘The liver is the central organ for digestion and detoxification and has unique metabolic and regenerative capacities.The hepatobiliary system originates from the foregut endoderm,in which cells undergo multiple events of cell proliferation,migration,and differentiation to form the liver parenchyma and ductal system under the hierarchical regulation of transcription factors.Studies on liver development and diseases have revealed that SRY-related high-mobility group box 9(SOx9)plays an important role in liver embryogenesis and the progression of hepatobiliary diseases.sox9 is not only a master regulator of cell fate determination and tissue morphogenesis,but also regulates various biological features of cancer,including cancer stemness,invasion,and drug resistance,making Sox9 a potential biomarker for tumor prognosis and progression.This review systematically summarizes the latest findings of sox9 in hepatobiliary development,homeostasis,and disease.We also highlight the value of sox9 as a novel biomarker and potential target for the clinical treatment of major liverdiseases.
基金the financial supports from the China Postdoctoral Fund(2019M662299)the project fund of innovation and entrepreneurship training program for college students in Shandong Province(S202011065125).
文摘The objective of this study was to develop an effective,potential wound dressing,which was constructed with a composite hydrogel of poly(vinyl alcohol)(PVA),carboxymethyl chitosan(CMC)and tannic acid(TA)by cryogenic treatment and freeze-drying method.The as-prepared TA-crosslinked PVA/CMC hydrogels exhibited interconnected pore structure with the mean pore size of roughly 3.7𝜇m.We found that the compressive strength and stiffness of composite hydrogel increased when the TA component was introduced.However,the PVA/CMC-TA hydrogel possessed obviously lower swell property than that of the TA-free PVA/CMC hydrogel.We also found that the TA addition significantly improved the antibacterial capacity of the as-prepared hydrogel.Moreover,the inhibition zone test showed that the antibacterial activity of PVA/CMC-TA against S.aureus bacteria was greater than that against E.coli.The biological results indicated that the PVA/CMC-TA hydrogel exhibited good cytocompatibility to natural human dermal fibroblasts.In summary,our PVA/CMC-TA composite hydrogel exhibited promising mechanical and antibacterial properties,which showed great potential application as wound healing materials.