In this paper, we construct Chebyshev biorthogonal multiwavelets, and use this multiwavelets to approximate signals (functions). The convergence rate for signal approximation is derived. The fast signal decomposition ...In this paper, we construct Chebyshev biorthogonal multiwavelets, and use this multiwavelets to approximate signals (functions). The convergence rate for signal approximation is derived. The fast signal decomposition and reconstruction algorithms are presented. The numerical examples validate the theoretical analysis.展开更多
The dynamics of two-dimensional rigid circles filled with chiral active particles are investigated by employing the overdamped Langevin dynamics simulations. Unidirectional rotation of rigid circles is observed, and t...The dynamics of two-dimensional rigid circles filled with chiral active particles are investigated by employing the overdamped Langevin dynamics simulations. Unidirectional rotation of rigid circles is observed, and the rotational angular velocity(ω) relies mainly on the length(l), the number(nB), and tilt angle(γ) of boards, and the angular velocity(ω)and area fraction(ρ) of chiral active particles. There are optimum values for these parameters at which the average angular velocity of circle reaches its maximum. The center-of-mass mean square displacement for circles drops by about two orders of magnitude for large angular velocity ω of chiral active particles with oscillations in the short-time regime. Our work demonstrates that nanofabricated objects with suitable designs immersed in a bath of chiral active particles can extract and rectify energy in a unidirectional motion.展开更多
Single-cell RNA sequencing(scRNA-seq)has emerged as a valuable tool for studying cellular heterogeneity in various fields,particularly in virological research.By studying the viral and cellular transcriptomes,the dyna...Single-cell RNA sequencing(scRNA-seq)has emerged as a valuable tool for studying cellular heterogeneity in various fields,particularly in virological research.By studying the viral and cellular transcriptomes,the dynamics of viral infection can be investigated at a single-cell resolution.However,limited studies have been conducted to investigate whether RNA transcripts from clinical samples contain substantial amounts of viral RNAs,and a specific computational framework for efficiently detecting viral reads based on scRNA-seq data has not been developed.Hence,we introduce DVsc,an open-source framework for precise quantitative analysis of viral infection from single-cell transcriptomics data.When applied to approximately 200 diverse clinical samples that were infected by more than 10 different viruses,DVsc demonstrated high accuracy in systematically detecting viral infection across a wide array of cell types.This innovative bioinformatics pipeline could be crucial for addressing the potential effects of surreptitiously invading viruses on certain illnesses,as well as for designing novel medicines to target viruses in specific host cell subsets and evaluating the efficacy of treatment.DVsc supports the FASTQ format as an input and is compatible with multiple single-cell sequencing platforms.Moreover,it could also be applied to sequences from bulk RNA sequencing data.DVsc is available at http://62.234.32.33:5000/DVsc.展开更多
In this work,a blue gallium nitride(GaN)micro-light-emitting-diode(micro-LED)-based underwater wireless optical communication(UWOC)system was built,and UWOCs with varied Maalox,chlorophyll,and sea salt concentrations ...In this work,a blue gallium nitride(GaN)micro-light-emitting-diode(micro-LED)-based underwater wireless optical communication(UWOC)system was built,and UWOCs with varied Maalox,chlorophyll,and sea salt concentrations were studied.Data transmission performance of the UWOC and the influence of light attenuation were investigated systematically.Maximum data transmission rates at the distance of 2.3 m were 933,800,910,and 790 Mbps for experimental conditions with no impurity,200.48 mg/m3 Maalox,12.07 mg/m3 chlorophyll,and 5 kg/m3 sea salt,respectively,much higher than previously reported systems with commercial LEDs.It was found that increasing chlorophyll,Maalox,and sea salt concentrations in water resulted in an increase of light attenuation,which led to the performance degradation of the UWOC.Further analysis suggests two light attenuation mechanisms,e.g.,absorption by chlorophyll and scattering by Maalox,are responsible for the decrease of maximum data rates and the increase of bit error rates.Based on the absorption and scattering models,excellent fitting to the experimental attenuation coefficient can be achieved,and light attenuation by absorption and scattering at different wavelengths was also investigated.We believe this work is instructive apply UWOC for practical applications.展开更多
文摘In this paper, we construct Chebyshev biorthogonal multiwavelets, and use this multiwavelets to approximate signals (functions). The convergence rate for signal approximation is derived. The fast signal decomposition and reconstruction algorithms are presented. The numerical examples validate the theoretical analysis.
基金Project supported by the National Natural Science Foundation of China(Grant Nos.21674096 and 21873082)
文摘The dynamics of two-dimensional rigid circles filled with chiral active particles are investigated by employing the overdamped Langevin dynamics simulations. Unidirectional rotation of rigid circles is observed, and the rotational angular velocity(ω) relies mainly on the length(l), the number(nB), and tilt angle(γ) of boards, and the angular velocity(ω)and area fraction(ρ) of chiral active particles. There are optimum values for these parameters at which the average angular velocity of circle reaches its maximum. The center-of-mass mean square displacement for circles drops by about two orders of magnitude for large angular velocity ω of chiral active particles with oscillations in the short-time regime. Our work demonstrates that nanofabricated objects with suitable designs immersed in a bath of chiral active particles can extract and rectify energy in a unidirectional motion.
基金supported by grants from the National Natural Science Foundation of China(Grant Nos.31830054 and 32293204)the Beijing Municipal Health Commission,China(JingYiYan2019-8Grant No.XTCX20180503).
文摘Single-cell RNA sequencing(scRNA-seq)has emerged as a valuable tool for studying cellular heterogeneity in various fields,particularly in virological research.By studying the viral and cellular transcriptomes,the dynamics of viral infection can be investigated at a single-cell resolution.However,limited studies have been conducted to investigate whether RNA transcripts from clinical samples contain substantial amounts of viral RNAs,and a specific computational framework for efficiently detecting viral reads based on scRNA-seq data has not been developed.Hence,we introduce DVsc,an open-source framework for precise quantitative analysis of viral infection from single-cell transcriptomics data.When applied to approximately 200 diverse clinical samples that were infected by more than 10 different viruses,DVsc demonstrated high accuracy in systematically detecting viral infection across a wide array of cell types.This innovative bioinformatics pipeline could be crucial for addressing the potential effects of surreptitiously invading viruses on certain illnesses,as well as for designing novel medicines to target viruses in specific host cell subsets and evaluating the efficacy of treatment.DVsc supports the FASTQ format as an input and is compatible with multiple single-cell sequencing platforms.Moreover,it could also be applied to sequences from bulk RNA sequencing data.DVsc is available at http://62.234.32.33:5000/DVsc.
基金supported by the National Natural Science Foundation of China(NSFC)(Nos.61705041 and61571135)Shanghai Sailing Program(No.17YF1429100)+2 种基金Shanghai Technical Standard Program(No.18DZ2206000)State Key Laboratory of Intense Pulsed Radiation Simulation and Effect Funding(No.SKLIPR1607)National Key Research and Development Program of China(No.2017YFB0403603)
文摘In this work,a blue gallium nitride(GaN)micro-light-emitting-diode(micro-LED)-based underwater wireless optical communication(UWOC)system was built,and UWOCs with varied Maalox,chlorophyll,and sea salt concentrations were studied.Data transmission performance of the UWOC and the influence of light attenuation were investigated systematically.Maximum data transmission rates at the distance of 2.3 m were 933,800,910,and 790 Mbps for experimental conditions with no impurity,200.48 mg/m3 Maalox,12.07 mg/m3 chlorophyll,and 5 kg/m3 sea salt,respectively,much higher than previously reported systems with commercial LEDs.It was found that increasing chlorophyll,Maalox,and sea salt concentrations in water resulted in an increase of light attenuation,which led to the performance degradation of the UWOC.Further analysis suggests two light attenuation mechanisms,e.g.,absorption by chlorophyll and scattering by Maalox,are responsible for the decrease of maximum data rates and the increase of bit error rates.Based on the absorption and scattering models,excellent fitting to the experimental attenuation coefficient can be achieved,and light attenuation by absorption and scattering at different wavelengths was also investigated.We believe this work is instructive apply UWOC for practical applications.