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RETRACTED:Exploring the Mechanism of Wu Ling San plus Flavor for the Treatment of Diabetic Macular Edema Based on Network Pharmacology and Molecular Docking Techniques
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作者 Kunmao Ke xiaoyun jiang +5 位作者 Yun Zhang Yekai Zhou Jian Zhao Junbiao Zhang Yanli Liu Meixia An 《Chinese Medicine》 CAS 2022年第3期33-50,共20页
Short Retraction Notice The paper does not meet the standards of “Chinese Medicine ". This article has been retracted to straighten the academic record. In making this decision the Editorial Board follows COPE&#... Short Retraction Notice The paper does not meet the standards of “Chinese Medicine ". This article has been retracted to straighten the academic record. In making this decision the Editorial Board follows COPE's Retraction Guidelines. The aim is to promote the circulation of scientific research by offering an ideal research publication platform with due consideration of internationally accepted standards on publication ethics. The Editorial Board would like to extend its sincere apologies for any inconvenience this retraction may have caused. Editor guiding this retraction: Prof. Maythem Saeed (EiC of CM) The full retraction notice in PDF is preceding the original paper, which is marked "RETRACTED". 展开更多
关键词 Diabetic Macular Edema Diabetic Retinopathy Wu Ling San plus Flavor Alkaloids ALIPHATIC Network Pharmacology Molecular Docking
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An inverse problem to estimate an unknown order of a Riemann-Liouville fractional derivative for a fractional Stokes' first problem for a heated generalized second grade fluid 被引量:2
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作者 Bo Yu xiaoyun jiang Haitao Qi 《Acta Mechanica Sinica》 SCIE EI CAS CSCD 2015年第2期153-161,共9页
In this paper,we propose a numerical method to estimate the unknown order of a Riemann-Liouville fractional derivative for a fractional Stokes' first problem for a heated generalized second grade fluid.The implicit n... In this paper,we propose a numerical method to estimate the unknown order of a Riemann-Liouville fractional derivative for a fractional Stokes' first problem for a heated generalized second grade fluid.The implicit numerical method is employed to solve the direct problem.For the inverse problem,we first obtain the fractional sensitivity equation by means of the digamma function,and then we propose an efficient numerical method,that is,the Levenberg-Marquardt algorithm based on a fractional derivative,to estimate the unknown order of a Riemann-Liouville fractional derivative.In order to demonstrate the effectiveness of the proposed numerical method,two cases in which the measurement values contain random measurement error or not are considered.The computational results demonstrate that the proposed numerical method could efficiently obtain the optimal estimation of the unknown order of a RiemannLiouville fractional derivative for a fractional Stokes' first problem for a heated generalized second grade fluid. 展开更多
关键词 Riemann-Liouville fractional derivative Generalized second grade fluid Inverse problem Implicit numerical method Fractional sensitivity equation
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The fast method and convergence analysis of the fractional magnetohydrodynamic coupled flow and heat transfer model for the generalized second-grade fluid 被引量:1
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作者 Xiaoqing Chi Hui Zhang xiaoyun jiang 《Science China Mathematics》 SCIE CSCD 2024年第4期919-950,共32页
In this paper,we first establish a new fractional magnetohydrodynamic(MHD)coupled flow and heat transfer model for a generalized second-grade fluid.This coupled model consists of a fractional momentum equation and a h... In this paper,we first establish a new fractional magnetohydrodynamic(MHD)coupled flow and heat transfer model for a generalized second-grade fluid.This coupled model consists of a fractional momentum equation and a heat conduction equation with a generalized form of Fourier law.The second-order fractional backward difference formula is applied to the temporal discretization and the Legendre spectral method is used for the spatial discretization.The fully discrete scheme is proved to be stable and convergent with an accuracy of O(τ^(2)+N-r),whereτis the time step-size and N is the polynomial degree.To reduce the memory requirements and computational cost,a fast method is developed,which is based on a globally uniform approximation of the trapezoidal rule for integrals on the real line.The strict convergence of the numerical scheme with this fast method is proved.We present the results of several numerical experiments to verify the effectiveness of the proposed method.Finally,we simulate the unsteady fractional MHD flow and heat transfer of the generalized second-grade fluid through a porous medium.The effects of the relevant parameters on the velocity and temperature are presented and analyzed in detail. 展开更多
关键词 fractional MHD coupled flow and heat transfer model generalized second-grade fuid fast method convergence analysis numerical simulation
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Generation of multi-freedom controllable helical beam through high-order Bessel beams[Invited]
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作者 xiaoyun jiang Minglie Hu Chen Xie 《Chinese Optics Letters》 SCIE EI CAS CSCD 2024年第9期31-36,共6页
In this Letter,we propose a scheme to generate helical optical fields with multi-freedom controllable features.High-quality helical lobes with adjustable radii,chirality,and lobe numbers can be generated by tuning the... In this Letter,we propose a scheme to generate helical optical fields with multi-freedom controllable features.High-quality helical lobes with adjustable radii,chirality,and lobe numbers can be generated by tuning the phase term of two paired highorder Bessel beams.Furthermore,the pitch of the helical beam can be controlled by combining another rotational phase term.The validity of our scheme is demonstrated in both simulations and experiments.Our scheme is promising to facilitate the rapid fabrication of helical structures with diverse parameters,which are critical in various applications,such as optical metamaterials,biology,and particle transport. 展开更多
关键词 helical beams high-order Bessel beams multi-freedom manipulation
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Genetic Architecture of Childhood Kidney and Urological Diseases in China
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作者 Ye Fang Hua Shi +66 位作者 Tianchao Xiang Jiaojiao Liu Jialu Liu Xiaoshan Tang Xiaoyan Fang Jing Chen Yihui Zhai Qian Shen Guomin Li Li Sun Yunli Bi Xiang Wang Yanyan Qian Bingbing Wu Huijun Wang Wenhao Zhou Duan Ma Jianhua Mao xiaoyun jiang Shuzhen Sun Ying Shen Xiaorong Liu Aihua Zhang Xiaowen Wang Wenyan Huang Qiu Li Mo Wang Xiaojie Gao Yubin Wu Fang Deng Ruifeng Zhang Cuihua Liu Li Yu Jieqiu Zhuang Qing Sun Xiqiang Dang Haitao Bai Ying Zhu Siguang Lu Bili Zhang Xiaoshan Shao Xuemei Liu Mei Han Lijun Zhao Yuling Liu Jian Gao Ying Bao Dongfeng Zhang Qingshan Ma Liping Zhao Zhengkun Xia Biao Lu Yulong Wang Mengzhun Zhao Jianjiang Zhang Shan Jian Guohua He Huifeng Zhang Bo Zhao Xiaohua LI Feiyan Wang Yufeng Li Hongtao Zhu Xinhui Luo Jinghai Li Jia Rao Hong Xu 《Phenomics》 2021年第3期91-104,共14页
Kidney disease is manifested in a wide variety of phenotypes,many of which have an important hereditary component.To delineate the genotypic and phenotypic spectrum of pediatric nephropathy,a multicenter registration ... Kidney disease is manifested in a wide variety of phenotypes,many of which have an important hereditary component.To delineate the genotypic and phenotypic spectrum of pediatric nephropathy,a multicenter registration system is being imple-mented based on the Chinese Children Genetic Kidney Disease Database(CCGKDD).In this study,all the patients with kidney and urological diseases were recruited from 2014 to 2020.Genetic analysis was conducted using exome sequencing for families with multiple affected individuals with nephropathy or clinical suspicion of a genetic kidney disease owing to early-onset or extrarenal features.The genetic diagnosis was confirmed in 883 of 2256(39.1%)patients from 23 provinces in China.Phenotypic profiles showed that the primary diagnosis included steroid-resistant nephrotic syndrome(SRNS,23.5%),glomerulonephritis(GN,32.2%),congenital anomalies of the kidney and urinary tract(CAKUT,21.2%),cystic renal disease(3.9%),renal calcinosis/stone(3.6%),tubulopathy(9.7%),and chronic kidney disease of unknown etiology(CKDu,5.8%).The pathogenic variants of 105 monogenetic disorders were identified.Ten distinct genomic disorders were identified as pathogenic copy number variants(CNVs)in 11 patients.The diagnostic yield differed by subgroups,and was highest in those with cystic renal disease(66.3%),followed by tubulopathy(58.4%),GN(57.7%),CKDu(43.5%),SRNS(29.2%),renal calcinosis/stone(29.3%)and CAKUT(8.6%).Reverse phenotyping permitted correct identification in 40 cases with clinical reassessment and unexpected genetic conditions.We present the results of the largest cohort of children with kidney disease in China where diagnostic exome sequencing was performed.Our data demonstrate the utility of family-based exome sequencing,and indicate that the combined analysis of genotype and phenotype based on the national patient registry is pivotal to the genetic diagnosis of kidney disease. 展开更多
关键词 Chronic kidney disease(CKD) Exome sequencing(ES) Steroid-resistant nephrotic syndrome(SRNS) Congenital anomalies of the kidney and urinary tract(CAKUT) Nephronophthisis(NPHP) Polycystic kidney disease(PKD)
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