The Association between Problematic Internet Use,Resilience,and Fatigue in First-Year Medical College Students in China:A Moderated Mediation Model

Background:Resilience is crucial for medical college students to thrive in the highly stressful environment of medical education.However,the prevalence of problematic internet use(PIU)in this population may negatively impact their resilience.This study investigated the influence of problematic online gaming(PG)and problematic social media use(PSMU)on the resilience of medical college students in China.Methods:A sample of 5075 first-year medical college students from four Chinese universities was studied.PG served as the independent variable,resilience as the dependent variable,fatigue as the mediator,and PSMU as the moderator.Structural equation modeling was conducted using LISREL 8.80.Additionally,a moderated mediation model was evaluated using the jAMM module in jamovi 2.6.13.Results:The study’s findings revealed significant negative correlations between resilience and the variables of PG,PSMU,and fatigue.Fatigue mediated the relationship between PG and resilience(B=−0.04,95%CI=[−0.05,−0.03]).PSMU moderated the direct relationship between PG and resilience with the interaction term PG×PSMU significant(B=−0.004,t=−6.501,p<0.001)and the first stage(PG→fatigue)of the mediation with PG×PSMU significant(B=0.055,t=8.351,p<0.001).The detrimental effects of PG on resilience were more pronounced among individuals with lower levels of PSMU.Conclusion:This study concluded that addressing PIU,particularly PG,is essential for fostering resilience in medical college students.While PSMU itself is maladaptive,the underlying social media engagement may serve a protective role through social support in mitigating the adverse effects of PG on resilience.

上转换纳米粒子的Y(OH)CO3壳层包覆及壳层转化

制备如异质核-壳结构等不同结构的镧系离子掺杂的上转换纳米材料对上转换纳米材料的基本性质研究及应用至关重要。在本工作中,我们采用简单的共沉淀方法在NaGdF4:Yb/Tm上转换纳米粒子表面包覆了无定形的Y(OH)CO3壳层。通过透射电子显微镜,X射线衍射,能量色散X射线荧光光谱等物理表征手段研究了所得纳米粒子的结构和形貌,结果表明Y(OH)CO3壳层可以在300°C附近转化形成YOF,形成异质核-壳结构。同时,初步研究结果显示该方法也可拓展用于其他无定形壳层的包覆及蛋黄-蛋壳结构纳米粒子的制备。这些结果表明这种方法在制备不同结构的上转换纳米材料方面有良好的应用前景。

Plasma SCF/c-kit Levels in Patients with Dipper and Non-Dipper Hypertension

Objective The aim of this study was to investigate the relationship between peripheral plasma stem cell factor (SCF)/c-kit levels and the types of dipper and non-dipper hypertension in hypertensive patients.Methods This cross-sectional study included newly diagnosed hypertensive patients who underwent 24-hour ambulatory blood pressure monitor (ABPM) between January 2009 and 2012 in Jiangning city. Patients were divided into the dipper group and the non-dipper group according to ABPM measurements. The levels of SCF and its receptor c-kit, tumor necrosis factor-α (TNF-α) and interleukin 6 (IL-6) in peripheral blood were measured via enzyme-linked immunosorbent assays. The serum levels of glucose and lipid were examined as well. The levels of SCF/c-kit were compared between the dippers and the non-dippers; and their correlation with 24-hour mean systolic blood pressure (MSBP), 24-hour mean diastolic blood pressure (MDBP), TNF-αand IL-6 were investigated using linear regression analyses statistically.Results A total of 247 patients with newly diagnosed hypertension were recruited into the study, including 116 non-dippers and 131 dippers. The levels of peripheral plasma SCF were higher in non-dipper group (907.1±52.7 ng/L vs. 778.7±44.6 ng/L; t=2.837, P<0.01), and the levels of c-kit were higher in non-dipper group too (13.2±1.7 μg/L vs 9.57±1.4 μg/L; t=2.831, P<0.01). Linear regression analysis revealed that SCF/ckit levels were significantly positively correlated with MSBP, MDBP, plasma TNF-α, and IL-6 levels (all P<0.01).Conclusions Peripheral plasma SCF/c-kit levels are higher in patients with non-dipper hypertension than those with dipper one, and significantly correlate with 24-hour MSBP, 24-hour MDBP, serum TNF-α and IL-6 levels.

Effects of Perioperative Pain Intervention on Postoperative Rehabilitation of Patients with Partial Resection of Lung Cancer

Objective: To explore the effect of perioperative pain intervention on postoperative rehabilitation of patients who underwent thoracoscopic partial resection of lung cancer. Methods: From January 2021 to May 2021, 100 patients with primary lung cancer who underwent thoracoscopic partial lung resection in Cardiopulmonary Department II of Cancer Center in our hospital were selected. They were divided into observation group and control group by random number table. Routine nursing after surgery was used in both groups, the observation group was given perioperative pain intervention nursing on the basis of routine nursing, and the postoperative pain (6 h, 12 h, 24 h, 48 h after operation), the rate of out-of-bed activity within 24 h after operation, lien chest tube time, the incidence of postoperative complications, the influence of pain on daily life, the satisfaction of patients with pain control methods and pain education and the satisfaction of discharged patients were observed and recorded. Results: There was no significant difference in general data (age, sex, educational level, course of disease, TNM stage of lung cancer, maximum diameter of tumor (CM), surgical site) between the two groups (P > 0.05);the NRS scores of the observation group at 6, 12, 24 and 48 hours after operation were all lower than those in the control group, and the difference was statistically significant (P < 0.05);after operation, the rate of 24 h out-of-bed activity in the observation group was higher than that in the control group, the lien chest tube time was shorter than the control group, and the incidence of postoperative complications was lower than that in the control group, the difference was statistically significant (P < 0.05);after operation, the effect level of pain in the observation group was lower than that in the control group, and the satisfaction of pain health education, pain control methods and discharged patients was higher than that in the control group, with statistical significance (P < 0.05). Conclusion: Perioperative pain intervention can effectively relieve postoperative pain state of patients, promote patients’ early out of bed and conducive to lung expansion, shorten the time of lien chest tube, reduce postoperative complications and the impact of pain on daily life, help patients recover as soon as possible, and improve the satisfaction of patients for medical treatment.

Parameter estimation method for a linear frequency modulation signal with a Duffing oscillator based on frequency periodicity

In view of the complexity of existing linear frequency modulation(LFM)signal parameter estimation methods and the poor antinoise performance and estimation accuracy under a low signal-to-noise ratio(SNR),a parameter estimation method for LFM signals with a Duffing oscillator based on frequency periodicity is proposed in this paper.This method utilizes the characteristic that the output signal of the Duffing oscillator excited by the LFM signal changes periodically with frequency,and the modulation period of the LFM signal is estimated by autocorrelation processing of the output signal of the Duffing oscillator.On this basis,the corresponding relationship between the reference frequency of the frequencyaligned Duffing oscillator and the frequency range of the LFM signal is analyzed by the periodic power spectrum method,and the frequency information of the LFM signal is determined.Simulation results show that this method can achieve high-accuracy parameter estimation for LFM signals at an SNR of-25 dB.

慢性心力衰竭患者容量管理护理专家共识

为规范临床护理实践,在充分借鉴心力衰竭诊疗共识和指南的基础上,参考国内外近10年的护理循证依据,通过两轮德尔菲专家函询和五次专家咨询讨论,结合国内心力衰竭医疗、护理专家的意见及临床实践经验,根据心力衰竭疾病特点,进行整理和总结,最终形成《慢性心力衰竭患者容量管理护理专家共识》。该共识包括慢性心力衰竭患者容量评估与容量超负荷感知、容量管理方法、生活方式管理、用药的护理、康复护理、延续性护理6个方面,对规范慢性心力衰竭患者容量管理临床护理实践有指导作用,可有效提高救治效果及临床护理质量。

Novel 2D/2D NiCo_(2)O_(4)/ZnCo_(2)O_(4)@rGO/CNTs self-supporting composite electrode with high hydroxyl ion adsorption capacity for asymmetric supercapacitor

The energy storage device has been urgently studied and developed to meet the increasing demand for energy and sustainable development.Due to the excellent conductivity of graphene and high performance of ZnCo_(2)O_(4)and NiCo_(2)O_(4),we design a self-supporting electrode based on vertically grown twodimensional/two-dimensional(2D/2D)NiCo_(2)O_(4)/ZnCo_(2)O_(4)hierarchical flakes on the carbon-based conductive substrate(NiCo_(2)O_(4)/ZnCo_(2)O_(4)@graphene/carbon nanotubes,NZ@GC).The density functional theory calculations indicate that the high OH-adsorption capacity of the NiCo_(2)O_(4)/ZnCo_(2)O_(4)nanosheets can significantly enhance the electrochemical reaction activity.NZ@GC shows a high capacitance of 1128.6 F g^(-1)at 1 A g^(-1).The capacitance retains 84.0%after 6000 cycles even at 10 A g^(-1).A hybrid supercapacitor is fabricated using NZ@GC and activated carbon,exhibiting a large energy density of 50.8 W h kg^(-1)at the power density of 800 W kg^(-1).After 9000 charge/discharge cycles,the supercapacitor still has 86.1%capacitance retention.The NZ@GC film has showed the potential as promising electrodes in high efficiency electrochemical energy storage devices.

Upconversion Nanoparticle-Organic Dye Nanocomposites for Chemo- and Biosensing

The emerging nanocomposite of lanthanide-doped upconversion nanoparticles(UCNPs)and organic dyes(ODs),which combines the advantages of each component,possesses a series of attractive properties,making the nanocomposite suitable for sensing.With the rising demand for chemo-and biosensing,a variety of sensors based on UCNP-OD nanocomposites have been developed for various analytes.The recent evolution of UCNP-OD-based sensors has enabled the detection of targeted analytes in situ,in vitro,and in vivo.In this review,beginning with a brief introduction to the fabrication and working principles of UCNP-OD-based sensors,we discuss UCNP-OD-based sensors for chemo-and biosensing.Concentrating on recent representative examples,we review UCNP-OD-based sensors for detecting different analytes,including ions,reactive oxygen species,reactive nitrogen species,gases,and biomolecules,by paying particular attentions to the design strategies and working principles.We lastly point out some remaining challenges and potential directions for the further development of UCNP-OD-based sensors.