In-situ controllable synthesis of carbon dots for patterned fluorescent wood films rapid fabrication strategy

Fluorescent-patterned materials are widely used in information storage and encryp-tion.However,preparing a patternedfluorescent display on a matrix currently requires a time-consuming(hours or even days)and complex multi-step process.Herein,a rapid and mild technique developed for the in-situ controllable synthe-sis offluorescent nitrogen-doped carbon dots(NCDs)on eco-friendly transparent woodfilms(TEMPO-oxidized carboxyl woodfilm[TOWF])within a few min-utes was developed.A wood skeleton was employed as the carbon precursor for NCD synthesis as well as the matrix for the uniform and controlled distribution of NCDs.Moreover,the in-situ synthesis mechanism for preparing NCDs in TOWF was proposed.The resultingfluorescent woodfilms have excellent tensile strength(310.0015.57 MPa),high transmittance(76.2%),high haze(95.0%),UV-blocking±properties in the full ultraviolet(UV)range,andfluorescent performance that can be modified by changing the heating parameters.Fluorescent patterning was sim-ply achieved by regulating the in-situ NCD synthesis regions,and thefluorescent patterns were formed within 10 s.Thesefluorescent-patterned woodfilms can effec-tively store and encrypt information,and they can interact with external information through a transparent matrix.This work provides a green and efficient strategy for fabricatingfluorescent information storage and encryption materials.

“可验证自学”继续医学教育模式下不同医院超声学科继续医学教育学习内容分析

目的探索在“可验证自学”继续医学教育模式下,三级与二级医院的超声医师继续医学教育学习内容的差异。方法纳入2022年6月至2023年6月北京协和医院40名超声医师,以及北京市第六医院9名超声医师,分别代表三级医院及二级医院超声学科,开展“可验证自学”继续医学教育课题研究。由课题组评估师对纳入医师的学习计划制定是否符合要求进行评估,并依据上报的学习内容和学分认证要求授予相应学分。比较不同医院间目标学分及实际获得学分,并分析不同医院之间学习计划构成及实际学习内容构成。结果两医院超声医师实际获得学分均可达到≥15学分的标准。北京协和医院与北京市第六医院超声医师的目标学分之间差异无统计学意义(P>0.05),北京协和医院超声医师的实际获得学分明显高于北京市第六医院[(18.8±4.6)vs(15.3±0.5),P<0.001]。北京协和医院超声医师的实际获得学分主要来源为科研相关学习内容,占比58.43%,包括“发表文章”(45.77%)和“科研项目及课题”(12.66%),而北京市第六医院科研相关目标及实际获得学分占比均为0。北京市第六医院超声医师的实际获得学分来源主要为各种形式的线上及线下自主学习。“病例回顾学习”为两医院超声医师的重要目标学分来源,但实际获得学分均明显低于目标学分(北京协和医院为0.64 vs 2.24,北京市第六医院为0 vs 3.72)。结论三级与二级医院的超声医师学分均可达标,但三级与二级医院医师在学习计划制定、学习内容构成方面均具有显著差异,提示继续医学教育模式的更新应充分考虑不同级别医院继续医学教育的需求及实际可完成情况。另外,建议在本学分授予方案的基础上,适当降低学习内容“病例回顾分析”的学分授予难度。

Understanding the role of transition metal single-atom electronic structure in oxysulfur radical-mediated oxidative degradation

The ubiquity of refractory organic matter in aquatic environments necessitates innovative removal strategies.Sulfate radical-based advanced oxidation has emerged as an attractive solution,offering high selectivity,enduring efficacy,and anti-interference ability.Among many technologies,sulfite activation,leveraging its cost-effectiveness and lower toxicity compared to conventional persulfates,stands out.Yet,the activation process often relies on transition metals,suffering from low atom utilization.Here we introduce a series of single-atom catalysts(SACs)employing transition metals on g-C_(3)N_(4)substrates,effectively activating sulfite for acetaminophen degradation.We highlight the superior performance of Fe/CN,which demonstrates a degradation rate constant significantly surpassing those of Ni/CN and Cu/CN.Our investigation into the electronic and spin polarization characteristics of these catalysts reveals their critical role in catalytic efficiency,with oxysulfur radical-mediated reactions predominating.Notably,under visible light,the catalytic activity is enhanced,attributed to an increased generation of oxysulfur radicals and a strengthened electron donation-back donation dynamic.The proximity of Fe/CN's d-band center to the Fermi level,alongside its high spin polarization,is shown to improve sulfite adsorption and reduce the HOMO-LUMO gap,thereby accelerating photo-assisted sulfite activation.This work advances the understanding of SACs in environmental applications and lays the groundwork for future water treatment technologies.

^(18)F-FDG PET/CT findings of paratesticular alveolar rhabdomyosarcoma

Rhabdomyosarcoma(RMS)originates from primitive mesenchymal cells and is the most common soft tissue tumor in childhood.^(18)F-fluoro-deoxyglucose(^(18)F-FDG)positron emission tomography(PET)/computed tomography(CT)has been reported to be valuable in RMS staging and risk stratification.Paratesticular RMS is a relatively uncommon form of RMS,most of which are of the embryonal histologic type.Paratesticular alveolar RMS is associated with aggressive behavior,high metastatic potential,and poor outcomes.To the best of our knowledge,^(18)F-FDG PET/CT imaging findings of paratesticular alveolar RMS have never been described.Here,we report on a 16-year-old boy's rare paratesticular alveolar RMS with multiple metastases and its findings on^(18)F-FDG PET/CT.This case also demonstrates the potential value of^(18)F-FDG PET/CT in RMS staging and treatment decisions,and may aid in the differential diagnosis.

Value of contrast-enhanced ultrasound combined with percutaneous ultrasound-guided fine-needle aspiration in the diagnosis of solid pancreatic lesions

Background:Contrast-enhanced ultrasound(CEUS)can detect lesions hidden in inflammatory regions and find necrosis or areas of severe fibrosis within the lesion.This retrospective study aimed to compare the diagnostic accuracy of solid pancreatic lesions using percutaneous ultrasound(US)-guided fine-needle aspiration(FNA)with or without CEUS assessment.Methods:Clinical,imaging,and pathologic data of 181 patients from January 2014 to December 2018 in Pecking Union Medical College Hospital,with solid pancreatic masses who underwent percutaneous US-FNA and ThinPrep cytologic test were retrospectively evaluated.Patients were divided into CEUS and US groups according to whether CEUS was performed before the biopsy.According to FNA cytology diagnoses,we combined non-diagnostic,neoplastic,and negative cases into a negative category.The positive category included malignant,suspicious,and atypical cases.The final diagnosis was confirmed by pathology or clinical and radiological follow-up for at least 12 months.The sensitivity,specificity,positive predictive value(PPV),negative predictive value(NPV),and accuracy of US-FNA were evaluated between the two groups.Results:This study enrolled 107 male and 74 female patients(average age:60 years).There were 58 cases in the US group and 123 cases in the CEUS group.No statistically significant differences in age,gender,or lesion size were found between the two groups.The diagnostic accuracy of the CEUS group was 95.1%(117/123),which was higher than the 86.2%(50/58)observed in the US group(P=0.036).The sensitivity,specificity,PPV,and NPV of the CEUS group were increased by 7.5%,16.7%,3.4%,and 18.8%,respectively,compared with the US group.However,the differences of the two groups were not statistically significant.Conclusions:Compared with the conventional US,the use of CEUS could improve the biopsy accuracy and avoid the need for a repeat biopsy,especially for some complicated FNA cases.