The healthy condition of the milling tool has a very high impact on the machining quality of the titanium components.Therefore,it is important to recognize the healthy condition of the tool and replace the damaged cut...The healthy condition of the milling tool has a very high impact on the machining quality of the titanium components.Therefore,it is important to recognize the healthy condition of the tool and replace the damaged cutter at the right time.In order to recognize the health condition of the milling cutter,a method based on the long short term memory(LSTM)was proposed to recognize tool health state in this paper.The various signals collected in the tool wear experiments were analyzed by time-domain statistics,and then the extracted data were generated by principal component analysis(PCA)method.The preprocessed data extracted by PCA is transmitted to the LSTM model for recognition.Compared with back propagation neural network(BPNN)and support vector machine(SVM),the proposed method can effectively utilize the time-domain regulation in the data to achieve higher recognition speed and accuracy.展开更多
OBJECTIVE:To observe the effects of electroacupuncture at Neiguan(PC6)at different time points on reperfusion arrhythmia(RA)after myocardial ischemia and reperfusion in rats,and to investigate the correlation of this ...OBJECTIVE:To observe the effects of electroacupuncture at Neiguan(PC6)at different time points on reperfusion arrhythmia(RA)after myocardial ischemia and reperfusion in rats,and to investigate the correlation of this protective effect with nerve growth factor(NGF),tyrosine kinase A(Trk A),tyrosine hydroxylase(TH),and norepinephrine(NE).METHODS:A total of 72 Sprague-Dawley male rats were randomly divided into six groups(n=12 rats/group):normal group(Norm),sham operation group(Sham),ischemia reperfusion group(I/R),pre-ischemic electroacupuncture group(EAI),pre-reperfusion electroacupuncture group(EAII),post-reperfusion electroacupuncture group(EAIII).The myocardial ischemia-reperfusion injury(MIRI)model was induced by occlusion of left anterior descending coronary artery for 20 min followed by reperfusion for 40 min in rats.With no intervention in the Norm group and only threading without ligation in the Sham group.Electroacupuncture pretreatment at 20 min/d for 7 d before ligation in the EAⅠgroup,20 min of electroacupuncture before reperfusion in the EAII group and 20 min of electroacupuncture after reperfusion in the EAIII group.The electrocardiogram(ECG)of each group was recorded throughout the whole process,and the success of the MIRI model was determined based on the changs of J-point and T-wave in the ECG.The arrhythmia score was used to record premature ventricular contractions,ventricular tachycardia and ventricular fibrillation during the reperfusion period to assess the reperfusion induced arrhythmias.The expression levels of NGF,Trk A,TH protein were measured by Western blot.Moreover,the expression levels of plasma and myocardial NE levels were detected by enzyme linked immunosorbent assay.RESULTS:The differences between Norm group and Sham group were not statistically significant in all indexes.Arrhythmia score,myocardial NGF,Trk A,TH,and NE expression were significantly higher in the I/R group compared with the Sham group.Arrhythmia score,myocardial NGF,Trk A,TH,and NE expression were significantly lower in each EA group compared with the I/R group.CONCLUSION:Electroacupuncture at Neiguan(PC6)at different time points can reduce the incidence and severity of reperfusion arrhythmias in rats.This protective effect is related to electroacupuncture regulating NGF,Trk A,TH,NE expression and reducing sympathetic hyperactivation.展开更多
Global synchronizability of duplex networks induced by three different intra-layer rewiring mechanisms is explored in this paper.The rewiring mechanisms are named as model-preserving rewiring(MPR), simply direct rewir...Global synchronizability of duplex networks induced by three different intra-layer rewiring mechanisms is explored in this paper.The rewiring mechanisms are named as model-preserving rewiring(MPR), simply direct rewiring(SDR), and degree-preserving rewiring(DPR), respectively. It is found that high switching frequencies will certainly enhance global synchronizability for WSWS duplex networks(i.e., each layer is independently formed by the algorithm proposed by Watts and Strogatz for generating small-world networks), ER-ER duplex networks(i.e., each layer is independently generated by the algorithm proposed by Erd ¨os and Renyi) and BA-BA duplex networks(i.e., each layer is independently formed by the classical BA algorithm). Namely,the faster the intra-layer couplings are reconnected, the faster the duplex networks reach global synchronization. Furthermore,we find that by increasing the intra-or inter-coupling strengths, the WS-WS time-varying network’s global synchronizability is enhanced. Take the WS-WS time-varying network as an example, we find that SDR mechanism has greater impact on global synchronizability than MPR mechanism and DPR mechanism. The related dynamical networks can arrive at synchronization faster by SDR than by MPR or DPR. Thus, we only study the effects of SDR on ER-ER duplex networks and BA-BA duplex networks. In addition, we obtain the fact via numerical simulations that, switching intra-layer coupling topologies under SDR mechanism has the greatest impact on the BA-BA duplex network, followed by the ER-ER network, and has the weakest influence on the WS-WS duplex network in terms of improving the global synchronizability when all the intra-layer networks are sparse and have the same average degree. Finally, the global synchronizability of WS-WS and BA-BA time-varying networks is improved compared with static duplex networks, the reason being that the networks tend to be randomized under SDR according to analysis of the networks’ average clustering coefficients and degree distributions.展开更多
基金National Natural Science Foundation of China(No.51805079)Shanghai Natural Science Foundation,China(No.17ZR1400600)Fundamental Research Funds for the Central Universities,China(No.16D110309)
文摘The healthy condition of the milling tool has a very high impact on the machining quality of the titanium components.Therefore,it is important to recognize the healthy condition of the tool and replace the damaged cutter at the right time.In order to recognize the health condition of the milling cutter,a method based on the long short term memory(LSTM)was proposed to recognize tool health state in this paper.The various signals collected in the tool wear experiments were analyzed by time-domain statistics,and then the extracted data were generated by principal component analysis(PCA)method.The preprocessed data extracted by PCA is transmitted to the LSTM model for recognition.Compared with back propagation neural network(BPNN)and support vector machine(SVM),the proposed method can effectively utilize the time-domain regulation in the data to achieve higher recognition speed and accuracy.
基金Transversal Project:Scenario-based Application of Wearable Devices for the Treatment of Cardiac Arrhythmias with Superficial Stimulation at the Neiguan(PC6)Point Research(BUCM-2022-JS-FW-003)。
文摘OBJECTIVE:To observe the effects of electroacupuncture at Neiguan(PC6)at different time points on reperfusion arrhythmia(RA)after myocardial ischemia and reperfusion in rats,and to investigate the correlation of this protective effect with nerve growth factor(NGF),tyrosine kinase A(Trk A),tyrosine hydroxylase(TH),and norepinephrine(NE).METHODS:A total of 72 Sprague-Dawley male rats were randomly divided into six groups(n=12 rats/group):normal group(Norm),sham operation group(Sham),ischemia reperfusion group(I/R),pre-ischemic electroacupuncture group(EAI),pre-reperfusion electroacupuncture group(EAII),post-reperfusion electroacupuncture group(EAIII).The myocardial ischemia-reperfusion injury(MIRI)model was induced by occlusion of left anterior descending coronary artery for 20 min followed by reperfusion for 40 min in rats.With no intervention in the Norm group and only threading without ligation in the Sham group.Electroacupuncture pretreatment at 20 min/d for 7 d before ligation in the EAⅠgroup,20 min of electroacupuncture before reperfusion in the EAII group and 20 min of electroacupuncture after reperfusion in the EAIII group.The electrocardiogram(ECG)of each group was recorded throughout the whole process,and the success of the MIRI model was determined based on the changs of J-point and T-wave in the ECG.The arrhythmia score was used to record premature ventricular contractions,ventricular tachycardia and ventricular fibrillation during the reperfusion period to assess the reperfusion induced arrhythmias.The expression levels of NGF,Trk A,TH protein were measured by Western blot.Moreover,the expression levels of plasma and myocardial NE levels were detected by enzyme linked immunosorbent assay.RESULTS:The differences between Norm group and Sham group were not statistically significant in all indexes.Arrhythmia score,myocardial NGF,Trk A,TH,and NE expression were significantly higher in the I/R group compared with the Sham group.Arrhythmia score,myocardial NGF,Trk A,TH,and NE expression were significantly lower in each EA group compared with the I/R group.CONCLUSION:Electroacupuncture at Neiguan(PC6)at different time points can reduce the incidence and severity of reperfusion arrhythmias in rats.This protective effect is related to electroacupuncture regulating NGF,Trk A,TH,NE expression and reducing sympathetic hyperactivation.
基金supported by the National Key Research and Development Program of China(Grant No.2018AAA0101100)the National Natural Science Foundation of China(Grant No.61973241)the Natural Science Foundation of Hubei Province(Grant No.2019CFA007)。
文摘Global synchronizability of duplex networks induced by three different intra-layer rewiring mechanisms is explored in this paper.The rewiring mechanisms are named as model-preserving rewiring(MPR), simply direct rewiring(SDR), and degree-preserving rewiring(DPR), respectively. It is found that high switching frequencies will certainly enhance global synchronizability for WSWS duplex networks(i.e., each layer is independently formed by the algorithm proposed by Watts and Strogatz for generating small-world networks), ER-ER duplex networks(i.e., each layer is independently generated by the algorithm proposed by Erd ¨os and Renyi) and BA-BA duplex networks(i.e., each layer is independently formed by the classical BA algorithm). Namely,the faster the intra-layer couplings are reconnected, the faster the duplex networks reach global synchronization. Furthermore,we find that by increasing the intra-or inter-coupling strengths, the WS-WS time-varying network’s global synchronizability is enhanced. Take the WS-WS time-varying network as an example, we find that SDR mechanism has greater impact on global synchronizability than MPR mechanism and DPR mechanism. The related dynamical networks can arrive at synchronization faster by SDR than by MPR or DPR. Thus, we only study the effects of SDR on ER-ER duplex networks and BA-BA duplex networks. In addition, we obtain the fact via numerical simulations that, switching intra-layer coupling topologies under SDR mechanism has the greatest impact on the BA-BA duplex network, followed by the ER-ER network, and has the weakest influence on the WS-WS duplex network in terms of improving the global synchronizability when all the intra-layer networks are sparse and have the same average degree. Finally, the global synchronizability of WS-WS and BA-BA time-varying networks is improved compared with static duplex networks, the reason being that the networks tend to be randomized under SDR according to analysis of the networks’ average clustering coefficients and degree distributions.
