Mature T-and natural killer(NK)-cell lymphomas are heterogeneous groups of malignant lymphoid neoplasms arising from T and NK cells. The incidence of mature T-and NK-cell lymphomas is 2.1 per 100,000 people, according...Mature T-and natural killer(NK)-cell lymphomas are heterogeneous groups of malignant lymphoid neoplasms arising from T and NK cells. The incidence of mature T-and NK-cell lymphomas is 2.1 per 100,000 people, according to a US report~1.展开更多
This study considers a superconducting electrodynamic maglev train of MLX01 type.The characteristics of the electromagnetic spring coefficient of a single bogie under different magnetomotive force(MF) of the supercond...This study considers a superconducting electrodynamic maglev train of MLX01 type.The characteristics of the electromagnetic spring coefficient of a single bogie under different magnetomotive force(MF) of the superconducting coil and standard air gap(Sag) were explored.In view of the small electromagnetic damping,a passive damping control strategy and an active damping control strategy were designed to increase the electromagnetic damping force between the superconducting coil and ground coil.Combined with the coupling numerical model of a single bogie,the vibration characteristics of the bogie in different directions with different damping control strategies were studied when the Sag and MF were fixed.The results can provide important theoretical support for stable operation control of maglev trains.展开更多
Based on the requirement of seismic reinforcement of bridge foundation on slope in the Chengdu-Lanzhou railway project,a shaking table model test of anti-slide pile protecting bridge foundation in landslide section is...Based on the requirement of seismic reinforcement of bridge foundation on slope in the Chengdu-Lanzhou railway project,a shaking table model test of anti-slide pile protecting bridge foundation in landslide section is designed and completed. By applying Wenchuan seismic waves with different acceleration peaks,the stress and deformation characteristics of bridge pile foundation and anti-slide pile are analyzed,and the failure mode is discussed. Results show that the dynamic response of bridge pile and anti-slide pile are affected by the peak value of seismic acceleration of earthquake,with which the stress and deformation of the structure increase. The maximum dynamic earth pressure and the moment of anti-slide piles are located near the sliding surface,while that of bridge piles are located at the top of the pile. Based on the dynamic response of structure,local reinforcement needs to be carried out to meet the requirement of the seismic design. The PGA amplification factor of the surface is greater than the inside,and it decreases with the increase of the input seismic acceleration peak. When the slope failure occurs,the tension cracks are mainly produced in the shallow sliding zone and the coarse particles at the foot of the slope are accumulated.展开更多
Carbon dioxide embolism is a rare but severe complication of laparoscopic hepatectomy.We reported a case of massive carbon dioxide embolism that developed into a rare paradoxical gas embolism during laparoscopic hepat...Carbon dioxide embolism is a rare but severe complication of laparoscopic hepatectomy.We reported a case of massive carbon dioxide embolism that developed into a rare paradoxical gas embolism during laparoscopic hepatectomy and resulted in reduced muscular power of the left upper extremity,severe pleural effusion and hypoalbuminemia after surgery.Fortunately,the patient fully recovered with positive prevention and postoperative treatment.This case report highlights that the surgeon and anaesthesiologist must be aware of the risks and the importance for prompt treatment when massive carbon dioxide embolism occurs.展开更多
Leaves are crucial for maintaining plant growth and development via photosynthesis,and their function is simultaneously regulated by a suite of phenotypic traits.Although much is known about the genetic architecture o...Leaves are crucial for maintaining plant growth and development via photosynthesis,and their function is simultaneously regulated by a suite of phenotypic traits.Although much is known about the genetic architecture of individual leaf traits,unraveling the genetic basis of complex leafmorphology remains a challenge.Based on the functional correlation and coordination ofmulti-traits,we divided 15 leaf morphological traits into three modules,comprising size(area,length,width,and perimeter),shape(leaf lobes,aspect ratio,circularity,rectangularity,and the relevant ratios),and color(red,green,and blue)for an ornamental tree species,Catalpa bungei.A total of 189 significant single-nucleotide polymorphisms were identified in the leaves of C.bungei:35,82,and 76 in the size,shape,and color modules,respectively.Four quantitative trait loci were common between the size and shape modules,which were closely related according to phenotype correlation,genetic mapping,and mRNA analysis.The color module was independent of them.Synergistic changes in the aspect ratio,leaf lobe,and circularity suggest that these traits could be the core indicators of the leaf shape module.The LAS and SRK genes,associated with leaf lobe and circularity,were found to function in plant defense mechanisms and the growth of leaves.The associations between the SRK and CRK2 genes and the leaf lobe and circularity traits were further verified by RT-qPCR.Our findings demonstrate the importance of integrating multi-trait modules to characterize leaf morphology and facilitate a holistic understanding of the genetic architecture of intraspecific leaf morphology diversity.展开更多
Superconducting nanowire single-photon detectors(SNSPDs)with low energy gaps exhibit superior single-photon sensitivity at infrared wavelengths[1],and state-of-the-art SNSPDs have the potential to meet the stringent d...Superconducting nanowire single-photon detectors(SNSPDs)with low energy gaps exhibit superior single-photon sensitivity at infrared wavelengths[1],and state-of-the-art SNSPDs have the potential to meet the stringent demands of mid-IR(MIR)detection[2].However,the nanowire thickness(~λ/1000-λ/600)and width(~λ/166-λ/60)are much smaller than those at MIR wavelengths,which results in weak absorption with a low detection efficiency[3].展开更多
基金supported by the Construction Project of Cancer Precision Diagnosis and Drug Treatment Technology(Grant No. ZLJZZDYYWZL04)the Clinical Oncology Research Fund of CSCO(Grant No. Y-SY2021MS-0240)+2 种基金the Haihe Yingcai(Tianjin)Project(Grant No. TJSJMYXYC-D2-039)the Tianjin Key Medical Discipline(Specialty)Construction Project grant(Grant No. TJYXZDXK-009A)the CACA-BeiGene Lymphoma Research Foundation(Grant No.CORP-117)。
文摘Mature T-and natural killer(NK)-cell lymphomas are heterogeneous groups of malignant lymphoid neoplasms arising from T and NK cells. The incidence of mature T-and NK-cell lymphomas is 2.1 per 100,000 people, according to a US report~1.
文摘This study considers a superconducting electrodynamic maglev train of MLX01 type.The characteristics of the electromagnetic spring coefficient of a single bogie under different magnetomotive force(MF) of the superconducting coil and standard air gap(Sag) were explored.In view of the small electromagnetic damping,a passive damping control strategy and an active damping control strategy were designed to increase the electromagnetic damping force between the superconducting coil and ground coil.Combined with the coupling numerical model of a single bogie,the vibration characteristics of the bogie in different directions with different damping control strategies were studied when the Sag and MF were fixed.The results can provide important theoretical support for stable operation control of maglev trains.
基金sponsored by the National Natural Science Foundation of China(51578467)
文摘Based on the requirement of seismic reinforcement of bridge foundation on slope in the Chengdu-Lanzhou railway project,a shaking table model test of anti-slide pile protecting bridge foundation in landslide section is designed and completed. By applying Wenchuan seismic waves with different acceleration peaks,the stress and deformation characteristics of bridge pile foundation and anti-slide pile are analyzed,and the failure mode is discussed. Results show that the dynamic response of bridge pile and anti-slide pile are affected by the peak value of seismic acceleration of earthquake,with which the stress and deformation of the structure increase. The maximum dynamic earth pressure and the moment of anti-slide piles are located near the sliding surface,while that of bridge piles are located at the top of the pile. Based on the dynamic response of structure,local reinforcement needs to be carried out to meet the requirement of the seismic design. The PGA amplification factor of the surface is greater than the inside,and it decreases with the increase of the input seismic acceleration peak. When the slope failure occurs,the tension cracks are mainly produced in the shallow sliding zone and the coarse particles at the foot of the slope are accumulated.
基金This work was supported by the Medicine and Health Science and Technology Project of Zhejiang Province,China(2018277726).
文摘Carbon dioxide embolism is a rare but severe complication of laparoscopic hepatectomy.We reported a case of massive carbon dioxide embolism that developed into a rare paradoxical gas embolism during laparoscopic hepatectomy and resulted in reduced muscular power of the left upper extremity,severe pleural effusion and hypoalbuminemia after surgery.Fortunately,the patient fully recovered with positive prevention and postoperative treatment.This case report highlights that the surgeon and anaesthesiologist must be aware of the risks and the importance for prompt treatment when massive carbon dioxide embolism occurs.
基金supported by the National Key Research and Development Plan of China(2021YFD2200202)the National Natural Science Foundation of China(32001337)。
文摘Leaves are crucial for maintaining plant growth and development via photosynthesis,and their function is simultaneously regulated by a suite of phenotypic traits.Although much is known about the genetic architecture of individual leaf traits,unraveling the genetic basis of complex leafmorphology remains a challenge.Based on the functional correlation and coordination ofmulti-traits,we divided 15 leaf morphological traits into three modules,comprising size(area,length,width,and perimeter),shape(leaf lobes,aspect ratio,circularity,rectangularity,and the relevant ratios),and color(red,green,and blue)for an ornamental tree species,Catalpa bungei.A total of 189 significant single-nucleotide polymorphisms were identified in the leaves of C.bungei:35,82,and 76 in the size,shape,and color modules,respectively.Four quantitative trait loci were common between the size and shape modules,which were closely related according to phenotype correlation,genetic mapping,and mRNA analysis.The color module was independent of them.Synergistic changes in the aspect ratio,leaf lobe,and circularity suggest that these traits could be the core indicators of the leaf shape module.The LAS and SRK genes,associated with leaf lobe and circularity,were found to function in plant defense mechanisms and the growth of leaves.The associations between the SRK and CRK2 genes and the leaf lobe and circularity traits were further verified by RT-qPCR.Our findings demonstrate the importance of integrating multi-trait modules to characterize leaf morphology and facilitate a holistic understanding of the genetic architecture of intraspecific leaf morphology diversity.
基金National Natural Science Foundation of China(12033002,62275118,62071218,62101240,62227820,12161141009,and 62288101)Innovation Program for Quantum Science and Technology(2021ZD0303401)+2 种基金Civil Aerospace Technology Research Project(D040305)Fundamental Research Funds for the Central Universities,the Priority Academic Program Development of Jiangsu Higher Education Institutions(PAPD)Postgraduate Research&Practice Innovation Program of Jiangsu Province.
文摘Superconducting nanowire single-photon detectors(SNSPDs)with low energy gaps exhibit superior single-photon sensitivity at infrared wavelengths[1],and state-of-the-art SNSPDs have the potential to meet the stringent demands of mid-IR(MIR)detection[2].However,the nanowire thickness(~λ/1000-λ/600)and width(~λ/166-λ/60)are much smaller than those at MIR wavelengths,which results in weak absorption with a low detection efficiency[3].