Extracting characteristic brain signals and simultaneous recording animals behaving could help us to understand the complex behavior of neuronal ensembles. Here, a system was established to record local field potentia...Extracting characteristic brain signals and simultaneous recording animals behaving could help us to understand the complex behavior of neuronal ensembles. Here, a system was established to record local field potentials (LFP) and extracellular signal or multiple-unit discharge and behavior synchronously by utilizing electrophysiology and integrated circuit technique. It comprised microelectrodes and micro-driver assembly, analog front end (AFE),while a computer (Pentium III ) was used as the platform for the graphic user interface, which was developed using the LabVIEW programming language. It was designed as a part of ongoing research to develop a portable wireless neural signal recording system. We believe that this information will be useful for the research of brain-computer interface.展开更多
Objective: To observe the effect of acupuncture, tuina plus rehabilitative therapy on lower limb motor dysfunction in infants with spastic cerebral palsy. Methods: A total of 60 infants with spastic cerebral palsy w...Objective: To observe the effect of acupuncture, tuina plus rehabilitative therapy on lower limb motor dysfunction in infants with spastic cerebral palsy. Methods: A total of 60 infants with spastic cerebral palsy were randomly divided into a treatment group and a control group by random digital table, 30 cases in each group. The treatment group was treated with acupuncture, tuina therapy plus rehabilitative therapy of Western medicine. The control group was simply treated with rehabilitative therapy of Western medicine, as same as that for the treatment group. The assessment was respectively given to the sick infants before the treatment and after the treatment of six months, to evaluate lying and rolling scores in dimension A, to evaluate sitting score in dimension B, to evaluate crawling and kneeling scores in dimension C, and evaluate standing score in dimension D in the gross motor functions and determine the muscle tone of the gastrocnemius muscle by modified Ashworth scale (MAS). Results: The differences were not statistically significant in comparison of the gross motor functions and the muscle tone of the gastrocnemius muscle between the two groups of sick infants before the treatment (P〉O.OS); after the treatment of six months, the above items were obviously improved in the two groups (P〈O.01), better in the treatment group than in the control group, with the statistical significance in the differences between the groups (P〈O.01). Conclusion: Acupuncture, tuina plus rehabilitative therapy of Western medicine are remarkable in the therapeutic effects in the treatment of motor disorders of the lower limbs in the sick infants with spastic cerebral palsy. This therapeutic method is safe, simple and convenient and needs to be clinically popularized and applied.展开更多
Objective:To observe the clinical effect of combined intermittent traction with warm needling for cervical radiculopathy.Methods:A total of 100 cases with cervical radiculopathy were randomly allocated into an observa...Objective:To observe the clinical effect of combined intermittent traction with warm needling for cervical radiculopathy.Methods:A total of 100 cases with cervical radiculopathy were randomly allocated into an observation group and a control group.Cases in the observation group were treated with intermittent traction coupled with warm needling,whereas cases in the control group were treated with warm needling alone.The therapeutic efficacy was observed after 20-day treatment.Results:The markedly effective rate in total was 90.0%in the observation group,versus 78.0%in the control group,showing a statistically significant difference(P<0.05).Conclusion:Combining intermittent traction with warm needling is safe,convenient and significantly effective for cervical radiculopathy.It is worth further popularization in clinical practice.展开更多
Objective: To observe the clinical efficacy of Chinese herbal fumigation plus beating with mulberry stick in treating heel pain. Methods: Sixty patients with heel pain were randomized into a treatment group and a c...Objective: To observe the clinical efficacy of Chinese herbal fumigation plus beating with mulberry stick in treating heel pain. Methods: Sixty patients with heel pain were randomized into a treatment group and a control group, 30 in each group. The treatment group was intervened by Chinese herbal fumigation plus beating with mulberry stick, and the control group was by orally taking Diclofenac Sodium Sustained Release Tablets plus external use of She Xiong Zhen Tong Gao (Moschus Analgesic Plaster). After one treatment course, the visual analogue scale (VAS) was used to observe the change of pain, and the clinical efficacies were also evaluated. Results: After intervention, the improvement of VAS score in the treatment group was more significant than that in the control group (P〈0.01). The total effective rate of the treatment group was significantly higher than that of the control group (P〈0.01). Conclusion: Chinese herbal fumigation plus beating with mulberry stick can produce a higher clinical efficacy than orally taking Diclofenac Sodium Sustained Release Tablets in treating heel pain.展开更多
Background Carotid intimal thickness(IMT),a marker of subclinical atherosclerosis,was widely used for predicting cardiovascular events. Recent studies have shown that inflammation plays a vital role in the development...Background Carotid intimal thickness(IMT),a marker of subclinical atherosclerosis,was widely used for predicting cardiovascular events. Recent studies have shown that inflammation plays a vital role in the development and progression of atherosclerosis. The neutrophil to lymphocyte ratio(NLR)is a new marker of inflammation because it is closely related to cardiovascular,metabolic and inflammatory diseases. However,the relationship between NLR and carotid atherosclerosis is currently unknown. Methods A total of 882 patients underwent blood sampling for neutrophil and lymphocyte counts,serum lipids,total homocysteine(tHcy),and carotid scan by ultrasonography(US)to evaluate abnormalities of carotid wall. Results NLR was found to be statistically significantly higher in the carotid atherosclerosis group(2.0±0.8 vs. 1.7±0.6,P<0.001). The NLR,expressed as both quartiles(odds ratio[OR],2.36;95% confidence interval[CI],1.37 to 3.47;P=0.001)and continuous values(OR,1.83;95% CI,1.43 to 2.33;P<0.001),was significantly associated with a higher risk for carotid atherosclerosis. The optimal NLR cutoff value for detecting carotid atherosclerosis was 1.60 based on receiver operating curve(ROC)analysis with a sensitivity of 64.0% and a specificity of 57.0%. Conclusion NLR is significantly associated with carotid atherosclerosis in newly diagnosed nondiabetic hypertensive patients.展开更多
基金Shandong Science Development FundGrant number:041120101
文摘Extracting characteristic brain signals and simultaneous recording animals behaving could help us to understand the complex behavior of neuronal ensembles. Here, a system was established to record local field potentials (LFP) and extracellular signal or multiple-unit discharge and behavior synchronously by utilizing electrophysiology and integrated circuit technique. It comprised microelectrodes and micro-driver assembly, analog front end (AFE),while a computer (Pentium III ) was used as the platform for the graphic user interface, which was developed using the LabVIEW programming language. It was designed as a part of ongoing research to develop a portable wireless neural signal recording system. We believe that this information will be useful for the research of brain-computer interface.
文摘Objective: To observe the effect of acupuncture, tuina plus rehabilitative therapy on lower limb motor dysfunction in infants with spastic cerebral palsy. Methods: A total of 60 infants with spastic cerebral palsy were randomly divided into a treatment group and a control group by random digital table, 30 cases in each group. The treatment group was treated with acupuncture, tuina therapy plus rehabilitative therapy of Western medicine. The control group was simply treated with rehabilitative therapy of Western medicine, as same as that for the treatment group. The assessment was respectively given to the sick infants before the treatment and after the treatment of six months, to evaluate lying and rolling scores in dimension A, to evaluate sitting score in dimension B, to evaluate crawling and kneeling scores in dimension C, and evaluate standing score in dimension D in the gross motor functions and determine the muscle tone of the gastrocnemius muscle by modified Ashworth scale (MAS). Results: The differences were not statistically significant in comparison of the gross motor functions and the muscle tone of the gastrocnemius muscle between the two groups of sick infants before the treatment (P〉O.OS); after the treatment of six months, the above items were obviously improved in the two groups (P〈O.01), better in the treatment group than in the control group, with the statistical significance in the differences between the groups (P〈O.01). Conclusion: Acupuncture, tuina plus rehabilitative therapy of Western medicine are remarkable in the therapeutic effects in the treatment of motor disorders of the lower limbs in the sick infants with spastic cerebral palsy. This therapeutic method is safe, simple and convenient and needs to be clinically popularized and applied.
文摘Objective:To observe the clinical effect of combined intermittent traction with warm needling for cervical radiculopathy.Methods:A total of 100 cases with cervical radiculopathy were randomly allocated into an observation group and a control group.Cases in the observation group were treated with intermittent traction coupled with warm needling,whereas cases in the control group were treated with warm needling alone.The therapeutic efficacy was observed after 20-day treatment.Results:The markedly effective rate in total was 90.0%in the observation group,versus 78.0%in the control group,showing a statistically significant difference(P<0.05).Conclusion:Combining intermittent traction with warm needling is safe,convenient and significantly effective for cervical radiculopathy.It is worth further popularization in clinical practice.
基金supported by Jiaxing Hospital of Chinese Medicine
文摘Objective: To observe the clinical efficacy of Chinese herbal fumigation plus beating with mulberry stick in treating heel pain. Methods: Sixty patients with heel pain were randomized into a treatment group and a control group, 30 in each group. The treatment group was intervened by Chinese herbal fumigation plus beating with mulberry stick, and the control group was by orally taking Diclofenac Sodium Sustained Release Tablets plus external use of She Xiong Zhen Tong Gao (Moschus Analgesic Plaster). After one treatment course, the visual analogue scale (VAS) was used to observe the change of pain, and the clinical efficacies were also evaluated. Results: After intervention, the improvement of VAS score in the treatment group was more significant than that in the control group (P〈0.01). The total effective rate of the treatment group was significantly higher than that of the control group (P〈0.01). Conclusion: Chinese herbal fumigation plus beating with mulberry stick can produce a higher clinical efficacy than orally taking Diclofenac Sodium Sustained Release Tablets in treating heel pain.
基金supported by the Natural Science Foundation of Guangdong Province(No.2015A030313660)the Science and technology Program of Guangdong Province(No.2014B020212008)+2 种基金the Science and Technology Program of Guangzhou(No.201604020143/201604020018/201604020186/201510010254/201803040012)the National Key Research and development Program of China(No.2017FYC1307603/2016YFC1301305)the Medical Science and Technology research Fund of Guangdong Province(No.B2018023)
文摘Background Carotid intimal thickness(IMT),a marker of subclinical atherosclerosis,was widely used for predicting cardiovascular events. Recent studies have shown that inflammation plays a vital role in the development and progression of atherosclerosis. The neutrophil to lymphocyte ratio(NLR)is a new marker of inflammation because it is closely related to cardiovascular,metabolic and inflammatory diseases. However,the relationship between NLR and carotid atherosclerosis is currently unknown. Methods A total of 882 patients underwent blood sampling for neutrophil and lymphocyte counts,serum lipids,total homocysteine(tHcy),and carotid scan by ultrasonography(US)to evaluate abnormalities of carotid wall. Results NLR was found to be statistically significantly higher in the carotid atherosclerosis group(2.0±0.8 vs. 1.7±0.6,P<0.001). The NLR,expressed as both quartiles(odds ratio[OR],2.36;95% confidence interval[CI],1.37 to 3.47;P=0.001)and continuous values(OR,1.83;95% CI,1.43 to 2.33;P<0.001),was significantly associated with a higher risk for carotid atherosclerosis. The optimal NLR cutoff value for detecting carotid atherosclerosis was 1.60 based on receiver operating curve(ROC)analysis with a sensitivity of 64.0% and a specificity of 57.0%. Conclusion NLR is significantly associated with carotid atherosclerosis in newly diagnosed nondiabetic hypertensive patients.