The dynamic characteristics related to micro-motions, such as mechanical vibration or rotation, play an essential role in classifying and recognizing ballistic targets in the midcourse, and recent researches explore w...The dynamic characteristics related to micro-motions, such as mechanical vibration or rotation, play an essential role in classifying and recognizing ballistic targets in the midcourse, and recent researches explore ways of extracting the micro-motion features from radar signals of ballistic targets. In this paper, we focus on how to investigate the micro-motion dynamic characteristics of the ballistic targets from the signals based on infrared (IR) detection, which is mainly achieved by analyzing the periodic fluctuation characteristics of the target IR irradiance intensity signatures. Simulation experiments demonstrate that the periodic characteristics of IR signatures can be used to distinguish different micro motion types and estimate related parameters. Consequently, this is possible to determine the micro-motion dynamics of ballistic targets based on IR detection.展开更多
[Objectives] The aim was to study chemical components of cultivated and wild Pinellia ternate(Thunb.) Breit and Typhonium flagelliforme(Lodd.) Blume by metabolomics technology based on UPLC-ESI-HRMS^n. [Methods] Chemi...[Objectives] The aim was to study chemical components of cultivated and wild Pinellia ternate(Thunb.) Breit and Typhonium flagelliforme(Lodd.) Blume by metabolomics technology based on UPLC-ESI-HRMS^n. [Methods] Chemical components of 27 samples of cultivated and wild P. ternate and T. flagelliforme were detected by using UPLC-ESI-HRMS^ntechnology. Differential markers between P. ternate and T. flagelliforme as well as cultivated and wild P. ternate were screened and identified by principal component analysis(PCA) and orthogonal partial least square-discriminate analysis(OPLS-DA). [Results]12 components of P. ternate(cultivated and wild variety) and T.flagelliforme and three components of cultivated and wild P. ternate were screened and identified by OPLS-DA. N-Acetyl-6-hydroxy-L-tryptophan and N-Phenylacetylglutamic were not detected in P. ternate,and these two components can be used as potential markers of P. ternate and T. flagelliforme. [Conclusions]UPLC-ESI-HRMS^n-based metabolomics technology could be used to quickly identify the chemical constituents of P. ternate and effectively distinguish P. ternate and T. flagelliforme,which has reference significance for the quality control of P. ternate.展开更多
Based on the needs of characteristic agricultural production for meteorological services in Huzhou City,we use C# programming language to develop the meteorological disaster monitoring and early warning platform for c...Based on the needs of characteristic agricultural production for meteorological services in Huzhou City,we use C# programming language to develop the meteorological disaster monitoring and early warning platform for characteristic agriculture in Huzhou City. This platform integrates the functions of meteorological and agricultural information monitoring,disaster identification and early warning,fine weather forecast product display,and data query and management,which effectively enhances the capacity of meteorological disaster monitoring and early warning for characteristic agriculture in Huzhou City,and provides strong technical support for the meteorological and agricultural departments in the agricultural meteorological services.展开更多
Five different trapping treatments, spraying attractant on bottle surface and spraying attractant inside the bottles with 0, 50,100 and 200 mL water, were set to trap Bactrocera dorsalis and B. cucurbitae in guava (P...Five different trapping treatments, spraying attractant on bottle surface and spraying attractant inside the bottles with 0, 50,100 and 200 mL water, were set to trap Bactrocera dorsalis and B. cucurbitae in guava (Psidium guajava) park. The results showed that when the usage of attractant was 1 g, both Haonian and Wende had trapping effect on B. dorsalis and B. cucurbitae. The trapping effect of Haonian on B. dorsalis was better than that of Wende, while their trapping effects on B. cucurbitae was just the opposite. The trapping effects of different treatments had great difference. The trapping effect of Haonian on two species of fruit flies enhanced with the increasing volume of water, and reached the ma^mum value as the water volume was 200 mL. With the increasing volume of water, the trap- ping effect of Wende on two species of fruit flies first increased, and then decreased, which reached the maximum value as the water volume was 50 mL. Different treatments with attractants spraying inside bottles had better trapping effects on two species of fruit flies than that spraying on bottle surface.展开更多
The rice planthopper,Sogatella furcifera,is a piercing-sucking insect pest of rice,Oryza sativa.It is responsible for significant crop yield losses,and has developed moderate to high resistance to several commonly use...The rice planthopper,Sogatella furcifera,is a piercing-sucking insect pest of rice,Oryza sativa.It is responsible for significant crop yield losses,and has developed moderate to high resistance to several commonly used chemical insecticides.We investigated the effects of the insect fungal pathogen Isaria javanica,alone and in combination with the chemical insecticide dinotefuran,on S.furcifera under both laboratory and field conditions.Our results show that I.javanica displays high infection efficiency and mortality for different stages of S.furcifera,reducing adult survival,female oviposition and ovary development.Laboratory bioassays showed that the combined use of I.javanica with a low dose(4-16 mg L^(-1))of dinotefuran resulted in higher mortality in S.furcifera than the use of I.javanica or dinotefuran alone.The combined treatment also had more significant effects on several host enzymes,including superoxide dismutase,catalase,peroxidase,and prophenol oxidase activities.In field trials,I.javanica effectively suppressed populations of rice planthoppers to low levels(22-64%of the level in untreated plots).Additional field experiments showed synergistic effects,i.e.,enhanced efficiency,for the control of S.furcifera populations using the combination of a low dose of I.javanica(1×10^(4) conidia mL^(-1))and a low dose of dinotefuran(~4.8-19.2%of normal field use levels),with control effects of>90%and a population level under 50 insects per 100 hills at 3-14 days post-treatment.Our findings indicate that the entomogenous fungus I.javanica offers an attractive biological control addition as part of the integrated pest management(IPM)practices for the control of rice plant pests.展开更多
In the last 10 years(2012-2021),five hypoxic events have been observed in summer in the central Bohai Sea(CBS).Frequent and persistent hypoxia will have an impact on the ecosystem of the CBS.In this paper,historical s...In the last 10 years(2012-2021),five hypoxic events have been observed in summer in the central Bohai Sea(CBS).Frequent and persistent hypoxia will have an impact on the ecosystem of the CBS.In this paper,historical sea temperature(ST),salinity(SAL),density(Den),and dissolved oxygen(DO)concentration data from three stations in the CBS are analyzed via the linear regression method,and the correlations between the stratification factors(ST,SAL,and Den)and DO concentration are determined.The thresholds of the stratification factors at the three stations in June in the year in which hypoxia occurred were determined and applied to survey data from 29 stations in late May to early June in 2022 in the CBS;this assessment found that the data from 19 stations indicated that hypoxia was about to occur.In August,the survey data showed that 14 out of the 29 stations indicated hypoxic conditions,of which 12 were from the predicted 19 stations,meaning that the estimation accuracy reached 63%.The same approach was applied to data from June 2023.The data for August from a bottom-type online monitoring system in the CBS verified the occurrence of hypoxic events around Sta.M2.The results show that the strength of the seawater stratification plays a leading role in hypoxic events in the summer in the CBS,and the thresholds of the stratification factors can be used to predict the occurrence of hypoxic events.展开更多
Trace zeolitic imidazolate framework-8(ZIF-8)-decorated activated carbon(AC)pellets were synthesized by a facile wet impregnation technique.After pyrolysis of the above composite material,the obtained carbon had a lar...Trace zeolitic imidazolate framework-8(ZIF-8)-decorated activated carbon(AC)pellets were synthesized by a facile wet impregnation technique.After pyrolysis of the above composite material,the obtained carbon had a large surface area and pore volume,with traces of Zn on its surface.Subsequently,the capacity of the ZIF8/AC samples to adsorb and remove phenol from aqueous media was evaluated in both batch and column experimental setups.The equilibrium adsorption capacity reached 155.24 mg·g^(-1),which was 2.3 times greater than that of the pure AC(46.24 mg·g^(-1)).In addition,adsorption kinetics were examined by pseudofirst and pseudosecond order models,and adsorption isotherms were fitted into Langmuir and Freundlich equations.The adsorbent could be easily filtered from the solution and washed with methanol and water,while maintaining an efficiency N90% after 4 cycles.The above results make it a potentially reusable candidate for water purification.展开更多
Expansins are cell-wall-loosening proteins that have multiple roles during plant development and stress- related processes. In this study, a novel expansin gene PwEXP2 was cloned by rapid amplification of cDNA ends ba...Expansins are cell-wall-loosening proteins that have multiple roles during plant development and stress- related processes. In this study, a novel expansin gene PwEXP2 was cloned by rapid amplification of cDNA ends based on the cDNA library of Picea wilsonii and EST fragment of PwEXP2. It was found that PwEXP2 coded 253 amino acids, and putative signal peptides exist at the N-terminal, followed by 8 cysteines, a HFD (His-Phe-Asp) conserved domain, and 4 tryptophan residues at the C-terminal. PwEXP2 was located in cytoplasm and nucleus when transformed in an onion epidermal cell. Quantitative real-time PCR assays showed that PwEXP2 was expressed in various tissues with a relatively high level in needles and low level in mature pollen. The expression level of PwEXP2 dramatically increased after seed germination. Gene expression profiles in abiotic stresses showed that PwEXP2 was induced by high temperature and osmotic stress but not involved in ABA-dependent signaling path- way. These results display the important roles of the PwEXP2 in plant development and multiple adversity stresses.展开更多
This article analyzes the problems existing in disinfection technology for Auricularia auricular in bag cultivation,introduces the concept of disinfection and sterilization technology and the technical status of humid...This article analyzes the problems existing in disinfection technology for Auricularia auricular in bag cultivation,introduces the concept of disinfection and sterilization technology and the technical status of humidification for disinfection of A.auricular in bag cultivation,analyzes the related problems caused by this type of technology and the reasons for the problems,and puts forward solutions to the technical problems.展开更多
Ovarian cancer is the most lethal and aggressive gynecological cancer with a high recurrence rate and is often diagnosed late.In ovarian cancer,multiple metabolic enzymes of lipid metabolism are abnormally expressed,r...Ovarian cancer is the most lethal and aggressive gynecological cancer with a high recurrence rate and is often diagnosed late.In ovarian cancer,multiple metabolic enzymes of lipid metabolism are abnormally expressed,resulting in metabolism disorder.As a characteristic pathway in polyunsaturated fatty acid(PUFA)metabolism,arachidonic acid(AA)metabolism is disturbed in ovarian cancer.Therefore,we established a 10-gene signature model to evaluate the prognostic risk of PUFA-related genes.This 10-gene signature has strong robustness and can play a stable predictive role in datasets of various platforms(TCGA,ICGC,and GSE17260).The high association between the risk subgroups and clinical characteristics indicated a good performance of the model.Our data further indicated that the high expression of LTA4H was positively correlated with poor prognosis in ovarian cancer.Deficiency of LTA4H enhanced sensitivity to Cisplatin and modified the characteristics of immune cell infiltration in ovarian cancer.Additionally,our results indicate that CCL5 was involved in the aberrant metabolism of the AA/LTA4H axis,which contributes to the reduction of tumor-infiltrating CD8+T cells and immune escape in ovarian cancer.These findings provide new insights into the prognosis and potential target of LTA4H/CCL5 in treating ovarian cancer.展开更多
The Sr/F co-doped CaP(Sr/F-CaP)coatings were prepared by micro-arc oxidation(MAO)under different voltages to modify the microstructure and corrosion behavior of Mg-4Zn-1Mn alloy.The surface and interface characteristi...The Sr/F co-doped CaP(Sr/F-CaP)coatings were prepared by micro-arc oxidation(MAO)under different voltages to modify the microstructure and corrosion behavior of Mg-4Zn-1Mn alloy.The surface and interface characteristics investigated using scanning electron microscopy(SEM)and energy dispersive X-ray spectrometer(EDS)showed that the MAO coatings displayed uneven crater-like holes and tiny cracks under lower voltage,while they exhibited relatively homogeneous crater-like holes without cracks under higher voltage.The thickness of MAO coatings increased with increasing voltage.The corrosion behavior of Mg-4Zn-1Mn alloy was improved by the MAO coatings.The MAO coatings prepared under 450 V and 500 V voltages possessed the best corrosion resistance with regard to the electrochemical corrosion tests and immersion corrosion tests,respectively.The MAO coatings fabricated under 450-500 V could provide a better corrosion protection effect for the substrate.展开更多
The degeneration of cholinergic neurons and cholinergic hypofunction are pathologies associated with Alzheimer's disease (AD). Muscarinic acetylcholine receptors (mAChRs) mediate acetylcholine-induced neurotransm...The degeneration of cholinergic neurons and cholinergic hypofunction are pathologies associated with Alzheimer's disease (AD). Muscarinic acetylcholine receptors (mAChRs) mediate acetylcholine-induced neurotransmission and five mAChR subtypes (M1-M5) have been identified. Among them, M1 mAChR is widely expressed in the central nervous system and has been implicated in many physiological and pathological brain functions. In addition, M1 mAChR is postulated to be an important therapeutic target for AD and several other neurodegenerative diseases. In this article, we review recent progress in understanding the functional involvement of M1 mAChR in AD pathology and in developing M1 mAChR agonists forAD treatment.展开更多
Objective:Regarding the secondary prevention of cardiovascular disease(CVD),there is great interest in preventing recurrent cardiovascular events(RCVEs).The prognostic importance of liver fibrosis scores(LFSs)has prev...Objective:Regarding the secondary prevention of cardiovascular disease(CVD),there is great interest in preventing recurrent cardiovascular events(RCVEs).The prognostic importance of liver fibrosis scores(LFSs)has previously been reported in variousCVDs.We hypothesized that LFSs might also be useful predictors for RCVEs in patients with prior cardiovascular events(CVEs).Herein,we aimed to evaluate the associations of LFSs with RCVEs in a large,real-world cohort of coronary artery disease(CAD)patients with a prior CVE.Methods:In this multicenter prospective study,6527 consecutive patients with angiography-diagnosed CAD who had experienced a prior CVE(acute coronary syndrome,stroke,percutaneous coronary intervention,or coronary artery bypass grafting)were enrolled.LFSs were computed according to the published formulas:non-alcoholic fatty liver disease fibrosis score(NFS)includes age,body mass index(BMI),impaired fasting glycemia or diabetes mellitus(DM),aspartate aminotransferase(AST)/alanine aminotransferase(ALT)ratio,platelets,and albumin;fibrosis-4(FIB-4)includes age,AST,ALT,and platelets;Forns score includes age,gamma-glutamyltransferase(GGT),and platelets;BARD includes BMI,AST/ALT ratio,and DM;GGT/platelet ratio includes GGT and platelets;AST/ALT ratio includes AST and ALT;and AST/platelet ratio index includes AST and platelets.The originally reported cutoffs were used for the categorization of low-,intermediate-,and high-score subgroups.All patients were followed up for the occurrence of RCVEs(comprising cardiovascular death,non-fatal myocardial infarction,and stroke).Cox and Poisson regression analyses were used to assess the relationship of baseline LFSs with the risk of RCVE.Results:During a mean follow-up of(54.67±18.80)months,532(8.2%)RCVEs were recorded.Intermediate and high NFS,FIB-4,Forns,and BARD scores were independently associated with an increased risk of RCVE(hazard ratios ranging from 1.42 to 1.75 for intermediate scores and 1.35 to 2.52 for high scores).In the subgroup analyses of sex,age,BMI,DM,and hypertension status,the increased risk of RCVEs with high LFSs(NFS,FIB-4,Forns,and BARD)was maintained across the different subgroups(all P<0.05).Conclusion:This study showed that LFSs are indeed independently associated with RCVEs,suggesting that LFSs may be used as novel tools for risk stratification in CAD patients with a prior CVE.展开更多
Increasing soil salinization has led to severe reductions in plant yield and quality,and investigating the mo-lecular mechanism of salt stress response is therefore an urgent priority.In this study,we systematically a...Increasing soil salinization has led to severe reductions in plant yield and quality,and investigating the mo-lecular mechanism of salt stress response is therefore an urgent priority.In this study,we systematically analyzed the response of cotton roots to salt stress using single-cell transcriptomics technology;56281 high-quality cells were obtained from 5-day-old lateral root tips of Gossypium arboreum under natural growth conditions and different salt treatments.Ten cell types with an array of novel marker genes were identified and confirmed by in situ RNA hybridization,and pseudotime analysis of some specific cell types revealed their potential differentiation trajectories.Prominent changes in cell numbers under salt stress were observed for outer epidermal and inner endodermal cells,which were significantly enriched in response to stress,amide biosynthetic process,glutathione metabolism,and glycolysis/gluconeogenesis.Analysis of differentially expressed genes identified in multiple comparisons revealed other functional ag-gregations concentrated on plant-type primary cell wall biogenesis,defense response,phenylpropanoid biosynthesis,and metabolic pathways.Some candidate differentially expressed genes encoding transcrip-tion factors or associated with plant hormones also responsive to salt stress were identified,and the func-tion of Ga03G2153,annotated as auxin-responsive GH3.6,was confirmed by virus-induced gene silencing.The GaGH3.6-silenced plants showed a severe stress-susceptible phenotype,and physiological and biochemical measurements indicated that they suffered more significant oxidative damage.These results suggest that GaGH3.6 might participate in cotton salt tolerance by regulating redox processes.We thus construct a transcriptional atlas of salt-stressed cotton roots at single-cell resolution,enabling us to explore cellular heterogeneity and differentiation trajectories and providing valuable insights into the mo-lecular mechanisms that underlie plant stress tolerance.展开更多
30% Fe CN/ZIS(30% Fe doped g-C_(3)N_(4)composited ZnIn_(2)S_(4)) was synthesized by a simple water bath method, via in-situ growth of abundant well-dispersed ZnIn_(2)S_(4)nanosheets on the Fe doped g-C_(3)N_(4)surface...30% Fe CN/ZIS(30% Fe doped g-C_(3)N_(4)composited ZnIn_(2)S_(4)) was synthesized by a simple water bath method, via in-situ growth of abundant well-dispersed ZnIn_(2)S_(4)nanosheets on the Fe doped g-C_(3)N_(4)surface. Experimental results showed the optimized 30% Fe CN/ZIS achieved the best photoreduction of Cr(VI)performance within a wide p H range, which was 9.5 times and 700 times higher than that of pure ZnIn_(2)S_(4)and 30% Fe CN(Fe doped g-C_(3)N_(4)). This is due to the intense synergy between the Fe-Nxbond and close interface contact produces a high-speed charge transfer channel, thus significantly improving the efficiency of optical carrier separation and migration. Meanwhile, UV-vis diffuse reflection spectra and photoluminescence spectroscopy showed that iron doping significantly narrowed the bandgap of gC_(3)N_(4), preventing electron-hole pair recombination. Further, the microstructures and charge separation properties were analyzed by scanning electron microscope, Photoluminescence Spectroscopy and timeresolved photoluminescence, which revealed the structure-activity relationship of composite structure and the synergistic mechanism of each functional component. This research should provide a viable technique for creating composites with high photocatalytic activity for the treatment of chromium-containing wastewater.展开更多
The lack of bioactivity of conventional medical materials leads to low osseointegration ability that may result in the occurrence of aseptic loosening in the clinic.To achieve high osseointegration,surface modificatio...The lack of bioactivity of conventional medical materials leads to low osseointegration ability that may result in the occurrence of aseptic loosening in the clinic.To achieve high osseointegration,surface modifications with multiple biofunctions including degradability,osteogenesis,angiogenesis and antibacterial properties are required.However,the functions of conventional bioactive coatings are limited.Thus novel biofunctional magnesium(Mg)coatings are believed to be promising candidates for surface modification of implant materials for use in bone tissue repair.By physical vapour deposition,many previous researchers have deposited Mg coatings with high purity and granular microstructure on titanium alloys,polyetheretherketone,steels,Mg alloys and silicon.It was found that the Mg coatings with high-purity could considerably control the degradation rate in the initial stage of Mg alloy implantation,which is the most important problem for the application of Mg alloy implants.In addition,Mg coating on titanium(Ti)implant materials has been extensively studied both in vitro and in vivo,and the results indicated that their corrosion behaviour and biocompatibility are promising.Mg coatings continuously release Mg ions during the degradation process,and the alkaline environment caused by Mg degradation has obvious antibacterial effects.Meanwhile,the Mg coating has beneficial effects on osteogenesis and osseointegration,and increases the new bone-regenerating ability.Mg coatings also exhibit favourable osteogenic and angiogenic properties in vitro and increased long-term bone formation and early vascularization in vivo.Inhibitory effects of Mg coatings on osteoclasts have also been proven,which play a great role in osteoporotic patients.In addition,in order to obtain more biofunctions,other alloying elements such as copper have been added to the Mg coatings.Thus,Mg-coated Ti acquired biofunctions including degradability,osteogenesis,angiogenesis and antibacterial properties.These novel multi-functional Mg coatings are expected to significantly enhance the long-term safety of bone implants for the benefit of patients.This paper gives a brief review of studies of the microstructure,degradation behaviours and biofunctions of Mg coatings,and directions for future research are also proposed.展开更多
Conversion of hexavalent chromium(Cr(Ⅵ))to trivalent chromium(Cr(Ⅲ))is an effective way to reduce its environmental risk,especially via photoreduction process.However,over a wide range of pH values,it is still a gre...Conversion of hexavalent chromium(Cr(Ⅵ))to trivalent chromium(Cr(Ⅲ))is an effective way to reduce its environmental risk,especially via photoreduction process.However,over a wide range of pH values,it is still a great challenge to achieve a high removal rate,and the disposal of produced Cr(Ⅲ)should be concerned.In this work,we implemented a high removal rate at 98%for Cr(Ⅵ)and total chromium(Cr(T))over a wide pH range(4–10)through the synergistic effect of adsorption,photoreduction and immobilization on the surface of Bi OBr_(0.25)I_(0.75).The substitution of bromine by iodine reduced the adsorption energy of Cr(Ⅵ)on Bi OBr_(0.25)I_(0.75),promoting the adsorption of Cr(Ⅵ).Meanwhile,the introduced iodine upshifted the conduction band(CB),enhancing the reduction ability for Cr(Ⅵ)to Cr(Ⅲ).The negative surface of Bi OBr_(0.25)I_(0.75)can capture Cr(Ⅲ),achieving a high removal rate for Cr(T).The p H-independent feature for Cr(Ⅵ)and Cr(Ⅲ)removal make Bi OBr_(0.25)I_(0.75)a potential material for chromium-containing wastewater treatment.This work provides an effective strategy for removing chromium over a wide p H range.展开更多
文摘The dynamic characteristics related to micro-motions, such as mechanical vibration or rotation, play an essential role in classifying and recognizing ballistic targets in the midcourse, and recent researches explore ways of extracting the micro-motion features from radar signals of ballistic targets. In this paper, we focus on how to investigate the micro-motion dynamic characteristics of the ballistic targets from the signals based on infrared (IR) detection, which is mainly achieved by analyzing the periodic fluctuation characteristics of the target IR irradiance intensity signatures. Simulation experiments demonstrate that the periodic characteristics of IR signatures can be used to distinguish different micro motion types and estimate related parameters. Consequently, this is possible to determine the micro-motion dynamics of ballistic targets based on IR detection.
基金Supported by Preferred Funding Plan of Science and Technology Activities Project for Overseas Students in Sichuan Province(2018-68)Key Project for Central Universities of Southwest Minzu University in 2018(2018NZD18)+1 种基金Research Project of Sichuan Province(2019YFS0174,2019YFS0191,2018JY0069)Innovative Scientific Research Project for Postgraduates of Southwest Minzu University(CX2017SZ092)
文摘[Objectives] The aim was to study chemical components of cultivated and wild Pinellia ternate(Thunb.) Breit and Typhonium flagelliforme(Lodd.) Blume by metabolomics technology based on UPLC-ESI-HRMS^n. [Methods] Chemical components of 27 samples of cultivated and wild P. ternate and T. flagelliforme were detected by using UPLC-ESI-HRMS^ntechnology. Differential markers between P. ternate and T. flagelliforme as well as cultivated and wild P. ternate were screened and identified by principal component analysis(PCA) and orthogonal partial least square-discriminate analysis(OPLS-DA). [Results]12 components of P. ternate(cultivated and wild variety) and T.flagelliforme and three components of cultivated and wild P. ternate were screened and identified by OPLS-DA. N-Acetyl-6-hydroxy-L-tryptophan and N-Phenylacetylglutamic were not detected in P. ternate,and these two components can be used as potential markers of P. ternate and T. flagelliforme. [Conclusions]UPLC-ESI-HRMS^n-based metabolomics technology could be used to quickly identify the chemical constituents of P. ternate and effectively distinguish P. ternate and T. flagelliforme,which has reference significance for the quality control of P. ternate.
基金Supported by Huzhou Science and Technology Program(2013GY06)Research Project of Huzhou Municipal Meteorological Bureau(hzqx201602)
文摘Based on the needs of characteristic agricultural production for meteorological services in Huzhou City,we use C# programming language to develop the meteorological disaster monitoring and early warning platform for characteristic agriculture in Huzhou City. This platform integrates the functions of meteorological and agricultural information monitoring,disaster identification and early warning,fine weather forecast product display,and data query and management,which effectively enhances the capacity of meteorological disaster monitoring and early warning for characteristic agriculture in Huzhou City,and provides strong technical support for the meteorological and agricultural departments in the agricultural meteorological services.
基金Supported by Special Fund for Agro-scientific Research in the Public Interest( 201103026-1)
文摘Five different trapping treatments, spraying attractant on bottle surface and spraying attractant inside the bottles with 0, 50,100 and 200 mL water, were set to trap Bactrocera dorsalis and B. cucurbitae in guava (Psidium guajava) park. The results showed that when the usage of attractant was 1 g, both Haonian and Wende had trapping effect on B. dorsalis and B. cucurbitae. The trapping effect of Haonian on B. dorsalis was better than that of Wende, while their trapping effects on B. cucurbitae was just the opposite. The trapping effects of different treatments had great difference. The trapping effect of Haonian on two species of fruit flies enhanced with the increasing volume of water, and reached the ma^mum value as the water volume was 200 mL. With the increasing volume of water, the trap- ping effect of Wende on two species of fruit flies first increased, and then decreased, which reached the maximum value as the water volume was 50 mL. Different treatments with attractants spraying inside bottles had better trapping effects on two species of fruit flies than that spraying on bottle surface.
基金funded by grants from the Science and Technology Planning Project of Guangzhou,China(202002020029)the Science and Technology Planning Project of Guangdong Province,China(2019B020217003)+1 种基金the National Key R&D Program of China(2018YFD02003)the National Key Technology Support Program of China(201303019-02)。
文摘The rice planthopper,Sogatella furcifera,is a piercing-sucking insect pest of rice,Oryza sativa.It is responsible for significant crop yield losses,and has developed moderate to high resistance to several commonly used chemical insecticides.We investigated the effects of the insect fungal pathogen Isaria javanica,alone and in combination with the chemical insecticide dinotefuran,on S.furcifera under both laboratory and field conditions.Our results show that I.javanica displays high infection efficiency and mortality for different stages of S.furcifera,reducing adult survival,female oviposition and ovary development.Laboratory bioassays showed that the combined use of I.javanica with a low dose(4-16 mg L^(-1))of dinotefuran resulted in higher mortality in S.furcifera than the use of I.javanica or dinotefuran alone.The combined treatment also had more significant effects on several host enzymes,including superoxide dismutase,catalase,peroxidase,and prophenol oxidase activities.In field trials,I.javanica effectively suppressed populations of rice planthoppers to low levels(22-64%of the level in untreated plots).Additional field experiments showed synergistic effects,i.e.,enhanced efficiency,for the control of S.furcifera populations using the combination of a low dose of I.javanica(1×10^(4) conidia mL^(-1))and a low dose of dinotefuran(~4.8-19.2%of normal field use levels),with control effects of>90%and a population level under 50 insects per 100 hills at 3-14 days post-treatment.Our findings indicate that the entomogenous fungus I.javanica offers an attractive biological control addition as part of the integrated pest management(IPM)practices for the control of rice plant pests.
基金The National Natural Science Foundation of China under contract Nos U2106211 and 42076197supported by the Data Center of Yantai Insti-tute of Coastal Zone Research,Chinese Academy of Sciences,China.Some of the data and samples were collected utilizing R/V Lanhai101 during open research cruise NORC2023-01supported by the NSFC Shiptime Sharing Project under contrac No.42249901.
文摘In the last 10 years(2012-2021),five hypoxic events have been observed in summer in the central Bohai Sea(CBS).Frequent and persistent hypoxia will have an impact on the ecosystem of the CBS.In this paper,historical sea temperature(ST),salinity(SAL),density(Den),and dissolved oxygen(DO)concentration data from three stations in the CBS are analyzed via the linear regression method,and the correlations between the stratification factors(ST,SAL,and Den)and DO concentration are determined.The thresholds of the stratification factors at the three stations in June in the year in which hypoxia occurred were determined and applied to survey data from 29 stations in late May to early June in 2022 in the CBS;this assessment found that the data from 19 stations indicated that hypoxia was about to occur.In August,the survey data showed that 14 out of the 29 stations indicated hypoxic conditions,of which 12 were from the predicted 19 stations,meaning that the estimation accuracy reached 63%.The same approach was applied to data from June 2023.The data for August from a bottom-type online monitoring system in the CBS verified the occurrence of hypoxic events around Sta.M2.The results show that the strength of the seawater stratification plays a leading role in hypoxic events in the summer in the CBS,and the thresholds of the stratification factors can be used to predict the occurrence of hypoxic events.
基金This work was supported by National Natural Science Foundation of China (21606252)the Key Research and Development Program of Xuzhou (KC19214)the Priority Academic Program Development of Jiangsu Higher Education Institutions.
文摘Trace zeolitic imidazolate framework-8(ZIF-8)-decorated activated carbon(AC)pellets were synthesized by a facile wet impregnation technique.After pyrolysis of the above composite material,the obtained carbon had a large surface area and pore volume,with traces of Zn on its surface.Subsequently,the capacity of the ZIF8/AC samples to adsorb and remove phenol from aqueous media was evaluated in both batch and column experimental setups.The equilibrium adsorption capacity reached 155.24 mg·g^(-1),which was 2.3 times greater than that of the pure AC(46.24 mg·g^(-1)).In addition,adsorption kinetics were examined by pseudofirst and pseudosecond order models,and adsorption isotherms were fitted into Langmuir and Freundlich equations.The adsorbent could be easily filtered from the solution and washed with methanol and water,while maintaining an efficiency N90% after 4 cycles.The above results make it a potentially reusable candidate for water purification.
基金supported by National Natural Science Foundation(Grant No.31270663)a grant from Agricultural Ministry of China(Grant No.2013ZX08009003-002-004)
文摘Expansins are cell-wall-loosening proteins that have multiple roles during plant development and stress- related processes. In this study, a novel expansin gene PwEXP2 was cloned by rapid amplification of cDNA ends based on the cDNA library of Picea wilsonii and EST fragment of PwEXP2. It was found that PwEXP2 coded 253 amino acids, and putative signal peptides exist at the N-terminal, followed by 8 cysteines, a HFD (His-Phe-Asp) conserved domain, and 4 tryptophan residues at the C-terminal. PwEXP2 was located in cytoplasm and nucleus when transformed in an onion epidermal cell. Quantitative real-time PCR assays showed that PwEXP2 was expressed in various tissues with a relatively high level in needles and low level in mature pollen. The expression level of PwEXP2 dramatically increased after seed germination. Gene expression profiles in abiotic stresses showed that PwEXP2 was induced by high temperature and osmotic stress but not involved in ABA-dependent signaling path- way. These results display the important roles of the PwEXP2 in plant development and multiple adversity stresses.
基金New Rural Construction Research Project of Suihua University(SXK120101).
文摘This article analyzes the problems existing in disinfection technology for Auricularia auricular in bag cultivation,introduces the concept of disinfection and sterilization technology and the technical status of humidification for disinfection of A.auricular in bag cultivation,analyzes the related problems caused by this type of technology and the reasons for the problems,and puts forward solutions to the technical problems.
基金supported by the General Program of National Natural Science Foundation of China(82272745,82072870,81972966)General Program of Natural Science Foundation of Beijing(7202224)+2 种基金the National Key Research and Development Program of China(2022YFA1104001)Youth Program of National Natural Science Foundation of China(82203102,82303801)Peking University Third Hospital Clinical Key Project(BYSY2022069)。
文摘Ovarian cancer is the most lethal and aggressive gynecological cancer with a high recurrence rate and is often diagnosed late.In ovarian cancer,multiple metabolic enzymes of lipid metabolism are abnormally expressed,resulting in metabolism disorder.As a characteristic pathway in polyunsaturated fatty acid(PUFA)metabolism,arachidonic acid(AA)metabolism is disturbed in ovarian cancer.Therefore,we established a 10-gene signature model to evaluate the prognostic risk of PUFA-related genes.This 10-gene signature has strong robustness and can play a stable predictive role in datasets of various platforms(TCGA,ICGC,and GSE17260).The high association between the risk subgroups and clinical characteristics indicated a good performance of the model.Our data further indicated that the high expression of LTA4H was positively correlated with poor prognosis in ovarian cancer.Deficiency of LTA4H enhanced sensitivity to Cisplatin and modified the characteristics of immune cell infiltration in ovarian cancer.Additionally,our results indicate that CCL5 was involved in the aberrant metabolism of the AA/LTA4H axis,which contributes to the reduction of tumor-infiltrating CD8+T cells and immune escape in ovarian cancer.These findings provide new insights into the prognosis and potential target of LTA4H/CCL5 in treating ovarian cancer.
文摘The Sr/F co-doped CaP(Sr/F-CaP)coatings were prepared by micro-arc oxidation(MAO)under different voltages to modify the microstructure and corrosion behavior of Mg-4Zn-1Mn alloy.The surface and interface characteristics investigated using scanning electron microscopy(SEM)and energy dispersive X-ray spectrometer(EDS)showed that the MAO coatings displayed uneven crater-like holes and tiny cracks under lower voltage,while they exhibited relatively homogeneous crater-like holes without cracks under higher voltage.The thickness of MAO coatings increased with increasing voltage.The corrosion behavior of Mg-4Zn-1Mn alloy was improved by the MAO coatings.The MAO coatings prepared under 450 V and 500 V voltages possessed the best corrosion resistance with regard to the electrochemical corrosion tests and immersion corrosion tests,respectively.The MAO coatings fabricated under 450-500 V could provide a better corrosion protection effect for the substrate.
基金supported by grants from the National Institutes of Health,USA(R01AG038710,R01AG021173,R01AG044420 and R01NS046673)the Alzheimer’s Association,the National Natural Science Foundation of China(91332112,81225008 and 81161120496)+1 种基金Fundamental Research Funds for the Central Universities of Chinathe Fok Ying Tung Education Foundation
文摘The degeneration of cholinergic neurons and cholinergic hypofunction are pathologies associated with Alzheimer's disease (AD). Muscarinic acetylcholine receptors (mAChRs) mediate acetylcholine-induced neurotransmission and five mAChR subtypes (M1-M5) have been identified. Among them, M1 mAChR is widely expressed in the central nervous system and has been implicated in many physiological and pathological brain functions. In addition, M1 mAChR is postulated to be an important therapeutic target for AD and several other neurodegenerative diseases. In this article, we review recent progress in understanding the functional involvement of M1 mAChR in AD pathology and in developing M1 mAChR agonists forAD treatment.
基金the Capital Health Development Fund(201614035)CAMS Major Collaborative Innovation Project(2016-I2M-1-011)+1 种基金Fundamental Research Funds for the Central Universities(2019-XHQN09)Youth Research Fund of Peking Union Medical College(2019-F11).
文摘Objective:Regarding the secondary prevention of cardiovascular disease(CVD),there is great interest in preventing recurrent cardiovascular events(RCVEs).The prognostic importance of liver fibrosis scores(LFSs)has previously been reported in variousCVDs.We hypothesized that LFSs might also be useful predictors for RCVEs in patients with prior cardiovascular events(CVEs).Herein,we aimed to evaluate the associations of LFSs with RCVEs in a large,real-world cohort of coronary artery disease(CAD)patients with a prior CVE.Methods:In this multicenter prospective study,6527 consecutive patients with angiography-diagnosed CAD who had experienced a prior CVE(acute coronary syndrome,stroke,percutaneous coronary intervention,or coronary artery bypass grafting)were enrolled.LFSs were computed according to the published formulas:non-alcoholic fatty liver disease fibrosis score(NFS)includes age,body mass index(BMI),impaired fasting glycemia or diabetes mellitus(DM),aspartate aminotransferase(AST)/alanine aminotransferase(ALT)ratio,platelets,and albumin;fibrosis-4(FIB-4)includes age,AST,ALT,and platelets;Forns score includes age,gamma-glutamyltransferase(GGT),and platelets;BARD includes BMI,AST/ALT ratio,and DM;GGT/platelet ratio includes GGT and platelets;AST/ALT ratio includes AST and ALT;and AST/platelet ratio index includes AST and platelets.The originally reported cutoffs were used for the categorization of low-,intermediate-,and high-score subgroups.All patients were followed up for the occurrence of RCVEs(comprising cardiovascular death,non-fatal myocardial infarction,and stroke).Cox and Poisson regression analyses were used to assess the relationship of baseline LFSs with the risk of RCVE.Results:During a mean follow-up of(54.67±18.80)months,532(8.2%)RCVEs were recorded.Intermediate and high NFS,FIB-4,Forns,and BARD scores were independently associated with an increased risk of RCVE(hazard ratios ranging from 1.42 to 1.75 for intermediate scores and 1.35 to 2.52 for high scores).In the subgroup analyses of sex,age,BMI,DM,and hypertension status,the increased risk of RCVEs with high LFSs(NFS,FIB-4,Forns,and BARD)was maintained across the different subgroups(all P<0.05).Conclusion:This study showed that LFSs are indeed independently associated with RCVEs,suggesting that LFSs may be used as novel tools for risk stratification in CAD patients with a prior CVE.
基金supported by the National Natural Science Foundation of China (31471548,32272179,and 31801404)the Central Plains Science and Technology Innovation Leader Project (214200510029)+4 种基金the Program for Innovative Research Team (in Science and Technology)in University of Henan Province (20IRTSTHN021)the Science and Technology Development Project of Anyang City (2022C01NY001 and 2022C01NY003)the Doctoral and Postdoctoral Research Fund of Anyang Institute of Technology (BSJ2019014 and BHJ2020002)the Key Scientific Research Project of Henan Higher Education Institutions of China (20A210006)the Zhongyuan Scholars Workstation (224400510020).
文摘Increasing soil salinization has led to severe reductions in plant yield and quality,and investigating the mo-lecular mechanism of salt stress response is therefore an urgent priority.In this study,we systematically analyzed the response of cotton roots to salt stress using single-cell transcriptomics technology;56281 high-quality cells were obtained from 5-day-old lateral root tips of Gossypium arboreum under natural growth conditions and different salt treatments.Ten cell types with an array of novel marker genes were identified and confirmed by in situ RNA hybridization,and pseudotime analysis of some specific cell types revealed their potential differentiation trajectories.Prominent changes in cell numbers under salt stress were observed for outer epidermal and inner endodermal cells,which were significantly enriched in response to stress,amide biosynthetic process,glutathione metabolism,and glycolysis/gluconeogenesis.Analysis of differentially expressed genes identified in multiple comparisons revealed other functional ag-gregations concentrated on plant-type primary cell wall biogenesis,defense response,phenylpropanoid biosynthesis,and metabolic pathways.Some candidate differentially expressed genes encoding transcrip-tion factors or associated with plant hormones also responsive to salt stress were identified,and the func-tion of Ga03G2153,annotated as auxin-responsive GH3.6,was confirmed by virus-induced gene silencing.The GaGH3.6-silenced plants showed a severe stress-susceptible phenotype,and physiological and biochemical measurements indicated that they suffered more significant oxidative damage.These results suggest that GaGH3.6 might participate in cotton salt tolerance by regulating redox processes.We thus construct a transcriptional atlas of salt-stressed cotton roots at single-cell resolution,enabling us to explore cellular heterogeneity and differentiation trajectories and providing valuable insights into the mo-lecular mechanisms that underlie plant stress tolerance.
基金supported by the National Natural Science Foundation of China (No. 22066022)。
文摘30% Fe CN/ZIS(30% Fe doped g-C_(3)N_(4)composited ZnIn_(2)S_(4)) was synthesized by a simple water bath method, via in-situ growth of abundant well-dispersed ZnIn_(2)S_(4)nanosheets on the Fe doped g-C_(3)N_(4)surface. Experimental results showed the optimized 30% Fe CN/ZIS achieved the best photoreduction of Cr(VI)performance within a wide p H range, which was 9.5 times and 700 times higher than that of pure ZnIn_(2)S_(4)and 30% Fe CN(Fe doped g-C_(3)N_(4)). This is due to the intense synergy between the Fe-Nxbond and close interface contact produces a high-speed charge transfer channel, thus significantly improving the efficiency of optical carrier separation and migration. Meanwhile, UV-vis diffuse reflection spectra and photoluminescence spectroscopy showed that iron doping significantly narrowed the bandgap of gC_(3)N_(4), preventing electron-hole pair recombination. Further, the microstructures and charge separation properties were analyzed by scanning electron microscope, Photoluminescence Spectroscopy and timeresolved photoluminescence, which revealed the structure-activity relationship of composite structure and the synergistic mechanism of each functional component. This research should provide a viable technique for creating composites with high photocatalytic activity for the treatment of chromium-containing wastewater.
基金supported by the National Key Research and Development Program of China(Nos.2016YFC1101804,2016YFC1100604)National Natural Science Foundation of China(Nos.51971222,51631009)+2 种基金Natural Science Foundation of Liaoning Province of China(No.2019-MS-326)Dongguan Innovative Research Team Program of China(No.2020607234007)China Postdoctoral Science Foundation(No.2021M690494).
文摘The lack of bioactivity of conventional medical materials leads to low osseointegration ability that may result in the occurrence of aseptic loosening in the clinic.To achieve high osseointegration,surface modifications with multiple biofunctions including degradability,osteogenesis,angiogenesis and antibacterial properties are required.However,the functions of conventional bioactive coatings are limited.Thus novel biofunctional magnesium(Mg)coatings are believed to be promising candidates for surface modification of implant materials for use in bone tissue repair.By physical vapour deposition,many previous researchers have deposited Mg coatings with high purity and granular microstructure on titanium alloys,polyetheretherketone,steels,Mg alloys and silicon.It was found that the Mg coatings with high-purity could considerably control the degradation rate in the initial stage of Mg alloy implantation,which is the most important problem for the application of Mg alloy implants.In addition,Mg coating on titanium(Ti)implant materials has been extensively studied both in vitro and in vivo,and the results indicated that their corrosion behaviour and biocompatibility are promising.Mg coatings continuously release Mg ions during the degradation process,and the alkaline environment caused by Mg degradation has obvious antibacterial effects.Meanwhile,the Mg coating has beneficial effects on osteogenesis and osseointegration,and increases the new bone-regenerating ability.Mg coatings also exhibit favourable osteogenic and angiogenic properties in vitro and increased long-term bone formation and early vascularization in vivo.Inhibitory effects of Mg coatings on osteoclasts have also been proven,which play a great role in osteoporotic patients.In addition,in order to obtain more biofunctions,other alloying elements such as copper have been added to the Mg coatings.Thus,Mg-coated Ti acquired biofunctions including degradability,osteogenesis,angiogenesis and antibacterial properties.These novel multi-functional Mg coatings are expected to significantly enhance the long-term safety of bone implants for the benefit of patients.This paper gives a brief review of studies of the microstructure,degradation behaviours and biofunctions of Mg coatings,and directions for future research are also proposed.
基金the Natural Science Foundation of Tianjin(No.18JCYBJC17700)the National Natural Science Foundation of China(Nos.21406164,21466035 and 22066022)。
文摘Conversion of hexavalent chromium(Cr(Ⅵ))to trivalent chromium(Cr(Ⅲ))is an effective way to reduce its environmental risk,especially via photoreduction process.However,over a wide range of pH values,it is still a great challenge to achieve a high removal rate,and the disposal of produced Cr(Ⅲ)should be concerned.In this work,we implemented a high removal rate at 98%for Cr(Ⅵ)and total chromium(Cr(T))over a wide pH range(4–10)through the synergistic effect of adsorption,photoreduction and immobilization on the surface of Bi OBr_(0.25)I_(0.75).The substitution of bromine by iodine reduced the adsorption energy of Cr(Ⅵ)on Bi OBr_(0.25)I_(0.75),promoting the adsorption of Cr(Ⅵ).Meanwhile,the introduced iodine upshifted the conduction band(CB),enhancing the reduction ability for Cr(Ⅵ)to Cr(Ⅲ).The negative surface of Bi OBr_(0.25)I_(0.75)can capture Cr(Ⅲ),achieving a high removal rate for Cr(T).The p H-independent feature for Cr(Ⅵ)and Cr(Ⅲ)removal make Bi OBr_(0.25)I_(0.75)a potential material for chromium-containing wastewater treatment.This work provides an effective strategy for removing chromium over a wide p H range.