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手法治疗胃食管反流病的随机对照试验的系统回顾和Meta分析
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作者 严梦蝶 石云舟 +6 位作者 刘艳琴 石悦 张梦竹 陈东男 叶森林 李诗音 冯跃 《Chinese Medicine and Natural Products》 CAS 2023年第4期143-157,共15页
目的:本研究旨在系统评价手法治疗胃食管反流病的临床疗效和安全性,为临床决策提供参考价值。方法:通过CNKI、万方、VIP、CBM、PubMed、Cochrane图书馆、Medline医学文献库和荷兰医学文摘数据库,检索手法治疗胃食管反流病的疗效的随机... 目的:本研究旨在系统评价手法治疗胃食管反流病的临床疗效和安全性,为临床决策提供参考价值。方法:通过CNKI、万方、VIP、CBM、PubMed、Cochrane图书馆、Medline医学文献库和荷兰医学文摘数据库,检索手法治疗胃食管反流病的疗效的随机对照试验(随机对照实验)研究。两名研究人员独立回顾了文献,提取了数据,并使用Cochrane偏倚风险评估工具进行了偏倚风险分析。进行荟萃分析和发表偏倚评估后,使用等级推荐、判定、发展和评价分级(GRADE)工具26对本荟萃分析中的数据进行评分。结果:纳入了11项随机对照试验,Meta分析显示,手法治疗组的总有效率(OR=4.63,95%CI[3.01,7.14],P<0.00001)和反流性疾病诊断问卷评分(WMD=-1.59,95%CI[-2.85,-0.33],P=0.01)均高于对照组。亚组分析显示,手法治疗vs西药组、手法治疗vs中药汤剂组、手法治疗+西药vs西药组、手法治疗+常规治疗vs常规治疗组的总有效率改善有显著差异。在11项试验中,有5项报告了不良事件,所有随机对照试验都存在发表偏倚的可能;亚组分析表明,年龄差异对异质性有显著影响;GRADE分析显示,所有结果指标的总体证据质量都很低,不支持本研究对结果的建议。结论:手法治疗在缓解胃食管反流病症状方面优于单纯药物治疗。 展开更多
关键词 胃食管反流病 手法治疗 推拿 按摩 系统回顾 荟萃分析
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Surface charge accumulation behavior and its influence on surface flashover performance of Al2O3-filled epoxy resin insulators under DC voltages 被引量:7
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作者 yanqin liu Guangning WU +3 位作者 Guoqiang GAO Jianyi XUE Yongqiang KANG Chaoqun SHI 《Plasma Science and Technology》 SCIE EI CAS CSCD 2019年第5期132-141,共10页
Surface charge accumulation on insulator surface can have great influence on surface flashover performance.An experimental system is established to investigate surface charge accumulation and decay characteristics of ... Surface charge accumulation on insulator surface can have great influence on surface flashover performance.An experimental system is established to investigate surface charge accumulation and decay characteristics of Al2O3-filled epoxy resin insulators in 0.1 MPa SF6 under DC voltages.Surface potential is recorded by a Kelvin vibrating probe connected to an electrostatic voltmeter.By pre-depositing charges on insulator surface,the influence of surface charges on surface flashover performance is studied.The results reveal that surface charge distribution appearance is the combined effect of electrode injection,back discharge and gas ionization.Surface charge distribution has obvious polarity effect.It is concentrated near the HV electrode under positive voltages and dispersed under negative voltages.The difference in positive and negative surface flashover voltage is attributed to the difference in surface charge distribution under DC voltages of different polarities.Surface charge decay contains two stages,which satisfies the law of double exponential function.At first stage,surface charge decays fast,which corresponds to charges escaping from shallower traps.While it decays slowly at the second stage,which corresponds to charge escaping from deeper traps.Surface charge decay process is dominated by surface conductivity mechanism.The pre-deposited charges on insulation surface have great influence on surface flashover performance.The deposited positive charges can increase positive flashover voltage but decrease negative flashover voltage. 展开更多
关键词 SURFACE charge electrode injection SURFACE FLASHOVER SURFACE CONDUCTIVITY pre-deposited CHARGES
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Propofol effectively inhibits lithium-pilocarpine-induced status epilepticus in rats via downregulation of N-methyl-D-aspartate receptor 2B subunit expression 被引量:3
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作者 Henglin wang Zhuoqiang Wang +4 位作者 Weidong Mi Cong Zhao yanqin liu Yongan Wang Haipeng Sun 《Neural Regeneration Research》 SCIE CAS CSCD 2012年第11期827-832,共6页
Status epilepticus was induced via intraperitoneal injection of lithium-pilocarpine.The inhibitory effects of propofol on status epilepticus in rats were judged based on observation of behavior,electroencephalography ... Status epilepticus was induced via intraperitoneal injection of lithium-pilocarpine.The inhibitory effects of propofol on status epilepticus in rats were judged based on observation of behavior,electroencephalography and 24-hour survival rate.Propofol(12.5-100 mg/kg) improved status epilepticus in a dose-dependent manner,and significantly reduced the number of deaths within 24 hours of lithium-pilocarpine injection.Western blot results showed that,24 hours after induction of status epilepticus,the levels of N-methyl-D-aspartate receptor 2A and 2B subunits were significantly increased in rat cerebral cortex and hippocampus.Propofol at 50 mg/kg significantly suppressed the increase in N-methyl-D-aspartate receptor 2B subunit levels,but not the increase in N-methyl-D-aspartate receptor 2A subunit levels.The results suggest that propofol can effectively inhibit status epilepticus induced by lithium-pilocarpine.This effect may be associated with downregulation of N-methyl-D-aspartate receptor 2B subunit expression after seizures. 展开更多
关键词 PROPOFOL status epilepticus N-methyl-D-aspartate receptor 2A 2B subunit cerebral cortex HIPPOCAMPUS ELECTROENCEPHALOGRAM
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Enhanced electrical transport performance through cation site doping in Y-doped Mg_(3.2)Sb_(2) 被引量:4
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作者 Yang Wang Xin Zhang +3 位作者 yanqin liu Yangzhong Wang Hongliang liu Jiuxing Zhang 《Journal of Materiomics》 SCIE EI 2020年第1期216-223,共8页
Mg_(3)Sb_(2)-based alloys are promising thermoelectric materials through n-type doping in Mg-rich growth conditions to overcome their intrinsic p-type behavior.First principle calculations are employed to investigate ... Mg_(3)Sb_(2)-based alloys are promising thermoelectric materials through n-type doping in Mg-rich growth conditions to overcome their intrinsic p-type behavior.First principle calculations are employed to investigate the dopant formation energy and electronic structures of Y-doped Mg_(3)Sb_(2).Results indicate that the Y atom is more favorable for substitution at the cation site.Simultaneously,the flattened band structure and increased density of state near the Fermi level of Y-doped Mg_(3)Sb_(2) indicate an enhanced electronic transport performance.The carrier concentration rises to 5.31×10^(19) cm^(-3) at room temperature,resulting in a significant increased power factor for Mg_(3.17)Y_(0.03)Sb_(2).The available optimization of electrical transport contributes to excellent thermoelectric performance,and a peak ZT~0.83 at 773 K was achieved for Y concentration x=0.03 in Mg_(3.2-x)Y_(x)Sb_(2).This work provides an alternative measure for optimizing the thermoelectric performance of n-type Mg_(3)Sb_(2) alloys by cation site doping. 展开更多
关键词 First principle calculations n-type Mg_(3)Sb_(2) Y doping Thermoelectric performance
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EXPONENTIALLY FITTED TRAPEZOIDAL SCHEME FOR A STOCHASTIC OSCILLATOR
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作者 Xiuling Yin Chengjian Zhang yanqin liu 《Journal of Computational Mathematics》 SCIE CSCD 2017年第6期801-813,共13页
This paper applies exponentially fitted trapezoidal scheme to a stochastic oscillator. The scheme is convergent with mean-square order 1 and symplectic. Its numerical solution oscillates and the second moment increase... This paper applies exponentially fitted trapezoidal scheme to a stochastic oscillator. The scheme is convergent with mean-square order 1 and symplectic. Its numerical solution oscillates and the second moment increases linearly with time. The numerical example verifies the analysis of the scheme. 展开更多
关键词 Exponentially fitted trapezoidal scheme Symplectic Mean-square order Second moment.
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