教育、科技、人才一体布局与科学基金发展战略

教育、科技、人才一体布局的统筹部署已经成为全面建设社会主义现代化国家的基础性、战略性支撑,深刻理解与把握教育、科技、人才一体布局重大意义对开展基础研究资助至关重要。在厘清一体布局对基础研究资助新要求的前提下,明确基础研究资助在科学研究、科学教育与人才培养有机结合中的定位和作用,完善国家自然科学基金资助管理体系,探索落实一体布局的着力点,从而提出新时代科学基金发展的战略思路,为教育强国、科技强国、人才强国建设提供源头支撑。

新时代高校教育、科技、人才一体化布局与科学基金发展策略

在世界新一轮科技产业革命加速演进的背景下,教育、科技、人才“三位一体”统筹布局成为我国全面建设社会主义现代化国家的基础性和战略性支撑。高校是科技强国、人才强国、教育强国三大战略的交汇点,科学基金作为促进创新链—产业链—资金链—人才链—学科链深度融合的重要渠道和枢纽,在一体布局下面临新的要求和挑战。文章围绕如何“有力统筹教育、科技、人才工作”的关键问题,明确新时代高校在教育、科技、人才一体布局的定位、内涵和要求,挖掘教育优先、科技自强、人才引领的现实困境与发展前景,以期为科学基金发展提出有针对性的方案和建议。

Python在结构化学可视化教学中的应用探索

介绍使用Python语言和科学计算库绘制结构化学中常见的氢原子s和p轨道波函数和电子云的图形的探索。在此过程中编写了多个脚本,通过数据处理和不同的生成算法实现波函数、电子云的可视化教学,旨在引导学生深入学习和理解波函数和电子云物理意义,提升学生自主思考和主动学习的能力。

Food-derived bio-functional peptides for the management of hyperuricemia and associated mechanism

Hyperuricemia,a metabolic disorder related to uric acid metabolism dysregulation,has become a common metabolic disease worldwide,due to changes in lifestyle and dietary structure.In recent years,owing to their high activity and few adverse effects,food-derived active peptides used as functional foods against hyperuricemia have attracted increasing attention.This article aims to focus on the challenge associated with peptide-specific preparation methods development,functional components identification,action mechanism(s)clarification,and bioavailability improvement.The current review proposed recent advances in producing the food-derived peptides with high anti-hyperuricemia activity by protein source screening and matched enzymatic hydrolysis condition adjusting,increased the knowledge about strategies to search antihyperuricemia peptides with definite structure,and emphasized the necessity of combining computer-aided approaches and activity evaluations.In addition,novel action mechanism mediated by gut microbiota was discussed,providing different insights from classical mechanism.Moreover,considering that little attention was paid previously on the structure-activity relationships of anti-hyperuricemia peptides,we collected the sequences from published studies and make a preliminary summary about the structure-activity relationships,which in turn provided guides for enzymatic hydrolysis optimization and bioavailability improvement.Hopefully,this article could promote the development,application and commercialization of food-derived anti-hyperuricemia peptides in the future.

不同坐姿的6岁儿童乘员在MPDB碰撞测试中头颈部损伤评价

本文中建立了具有详细解剖学结构且经过验证的3种不同坐姿6岁儿童乘员有限元模型,并施加以某款SUV 50%重叠移动渐进变形壁障(mobile progressive deformable barrier,MPDB)碰撞试验获得的减速度曲线,通过对比不同坐姿下头颈部运动学和脑组织生物力学参数,探究坐姿对6岁儿童头颈部损伤程度的影响。结果表明:MPDB碰撞工况中,头部旋转载荷是造成头部损伤的主要原因,且坐姿角度的增加会导致脑组织惯性损伤风险增大,但颈部损伤风险并无增加的趋势。

Review on status of groundwater database and application prospect in deep-time digital earth plan

Groundwater is an important water resource.The total amount of active groundwater in a hydrological cycle is about 3.5 times that of the total amount of surface water.The information in the deep groundwater records the material exchange and dynamics in the earth’s evolution,which is an important aspect of the Deep-Time Digital Earth(DDE)plan.In recent years,scientists have discussed the distribution of transboundary aquifers and the environmental significance of groundwater resources through groundwater databases established by international organizations,such as the Global Groundwater Information System and the chronicles consortium,and national institutes,such as national geological surveys.The application of the groundwater database in the DDE plan,however,has been limited by the management,interactivity,and monitoring method of the groundwater data.The ability to further integrate data that are private and scattered across research institutions and individuals,while establishing an open,unified,and shared groundwater data platform,is essential to enhance our understanding of groundwater,ranging from shallow to deep water,which is a goal of the DDE plan.In this study,we introduced the current situation of groundwater database operations in domestic and international research and provided frontier research with groundwater big data.Considering the related objectives of the DDE plan and the limitations of existing groundwater databases,we proposed an improvement plan and new prospects for applying groundwater databases in the research of the deep earth.

Solving the Nonlinear Variable Order Fractional Differential Equations by Using Euler Wavelets

An Euler wavelets method is proposed to solve a class of nonlinear variable order fractional differential equations in this paper.The properties of Euler wavelets and their operational matrix together with a family of piecewise functions are first presented.Then they are utilized to reduce the problem to the solution of a nonlinear system of algebraic equations.And the convergence of the Euler wavelets basis is given.The method is computationally attractive and some numerical examples are provided to illustrate its high accuracy.

Estimation of reservoir temperature using silica and cationic solutes geothermometers:a case study in the Tengchong geothermal area

Reservoir temperature estimation is vitally important for assessing the exploitation potential of a geothermal field.In this study,the concentrations of major chemical constituents in geothermal water sampled from boiling and hot springs in the Tengchong hydrothermal area were measured,and quartz and cationic solutes geothermometers were used to calculate subsurface temperatures.Log(Q/K) diagrams and Na-K-Mg triangular diagrams were applied to evaluating the equilibrium status of geothermal water samples with regard to reservoir minerals,and results were used to select suitable geothermometers.The results show that samples RH01,RH03,RH04,RH05,and LL16 were in or very close to full equilibrium with the selected minerals,and therefore a NaK geothermometer is appropriate.A K/Mg geothermometer,however,is applicable to LP08 and PZH18 whose chemical compositions adjusted to the shallow reservoir temperatures during their re-equilibrium processes.In contrast,cationic solute geothermometers are unsuitable for SQ20 and RH07,which are categorized as immature water in the Na-K-Mg diagram;a quartz geothermometer was adopted to evaluate the corresponding subsurface temperatures of these samples.According to the reservoir temperature estimation made in this study,there is at least one high-temperature reservoir below Rehai with a possible temperature range of 210-270 ℃.

Fluorination-mitigated high-current degradation of amorphous InGaZnO thin-film transistors

As growing applications demand higher driving currents of oxide semiconductor thin-film transistors(TFTs),severe instabilities and even hard breakdown under high-current stress(HCS)become critical challenges.In this work,the triggering voltage of HCS-induced self-heating(SH)degradation is defined in the output characteristics of amorphous indium-galliumzinc oxide(a-IGZO)TFTs,and used to quantitatively evaluate the thermal generation process of channel donor defects.The fluorinated a-IGZO(a-IGZO:F)was adopted to effectively retard the triggering of the self-heating(SH)effect,and was supposed to originate from the less population of initial deep-state defects and a slower rate of thermal defect transition in a-IGZO:F.The proposed scheme noticeably enhances the high-current applications of oxide TFTs.

Vitamin B_(9) derived nitrogen-doped graphene for metal-free aerobic oxidation of biomass-derived chemicals

A superior carbocatalyst ultrahigh N-doped graphene(NG) was prepared by a novel self-sacrificial templating method of one-step annealing vitamin B_(9).The NG catalyst with pyrolysis temperature of 800℃(abbreviated VB_(9)-NG-800) has an ultrahigh nitrogen content of 13.5 wt% and demonstrated the highest activity for the oxidation of bio-based alcohols and terpenes with molecular oxygen without any additives.Systematic characterizations and quantum-chemical calculations further manifested that high contents of graphitic N and pyridinic N species in VB_(9)-NG-800 promoted the generation of·O_(2)^(-)active species from molecular oxygen effortlessly,resulting in excellent catalytic performance for aerobic oxidation.

532nm眼底激光联合康柏西普对糖尿病视网膜病变患者VEGF和PEDF的影响

目的:研究532nm眼底激光联合康柏西普对糖尿病视网膜病变患者血管内皮生因子(vascular endothelial growth factor,VEGF)水平及色素上皮衍生因子(Pigment Epithelium-Derived Factor,PEDF)的影响.方法:选取2018年1月至2019年3月于我院接受治疗的80例糖尿病视网膜病变的患者,按照数字表随机分组法分为观察组和对照组各40例.对照组患者采取康柏西普玻璃体腔注射治疗,观察组在对照组基础上联合使用532nm眼底激光.比较两组患者治疗前和治疗3个月后VEGF和PEDF水平、比较两组治疗前后视网膜厚度、视网膜血管瘤数量、渗漏面积及无灌注面积,并观察不良反应发生情况.结果:治疗后,两组VEGF增高而PEDF降低,且观察组VEGF低于对照组,PEDF高于对照组(P<0.05).治疗后两组视网膜厚度较治疗前降低,而观察组低于对照组(P<0.05).治疗后观察组血管瘤数量、渗漏面积显著低于对照组(P<0.05).两组不良反应无显著差异.结论:532nm眼底激光联合康柏西普治疗糖尿病视网膜病变可有效抑制视网膜新生血管生成,临床疗效好,安全性好,值得临床推广.

Surface Water and Groundwater Interactions in Wetlands

Wetland ecosystems are critical habitats for various types of wild lives and are important components of global ecosystem. However, with climate change and human activities, wetlands are facing with degradation. Surface water and groundwater(SW-GW) interactions play an essential role in matter and energy cycling in wetlands, and therefore affect the evolution and health of wetlands. But the role of groundwater in wetland ecosystems has been neglected or simplified. In this paper, we reviewed how surface water interacts with groundwater, and made a systematic summarization of the role of SW-GW interactions(such as maintaining water balance and biological diversity and removing pollution) in wetland ecological functions. We also reviewed the methods to investigate, simulate and quantify SW-GW interactions and related reactions. Finally, we illustrated how climate change and human activities affect SW-GW interactions and therefore affect wetland functions. We highlight the importance of groundwater in wetlands and the urgency to intensify the research in integrated multidisciplinary monitoring and simulation methods, dominant variables and thresholds and integrated water resources management of SW-GW interactions, and further aim to stimulate better protection and restoration of wetlands all over the world.

Development of autonomous navigation controller for agricultural vehicles

Agricultural vehicles are adopted to undertake farming tasks by traversing along crop rows in the field.Working quality depends significantly on the driving skills of the operator.Automatic guidance has been introduced into agriculture to achieve high-accuracy path tracking during the last decades,which contributes considerably to straight-line navigation.The objective of this research was to develop an autonomous navigation controller that allowed movement autonomy for various agricultural vehicles.Three wheel-type vehicles were used as the test platform featuring automatic steering,hydrostatic transmission and speed control,which included a rice transplanter,a high-clearance sprayer and a tractor.A dual-antenna RTK-GNSS receiver was attached to the vehicles to provide spatial information on both positioning and heading by using the RTX service from Trimble.A path planning method was proposed to create a straight-line reference path by giving two points,and the target path was determined according to the vehicle initial status and working assignment.Headland turning was comprehensively taken into account by listing different turn patterns in order to realize autonomous navigation at the headland.The navigation controller hardware was fabricated for program execution,data processing and information communication with peripherals.A human-machine interface was designed for the operator to complete basic setting,path planning and navigation control by providing controls.Field experiments were conducted to evaluate the performance and versatility of the newly developed autonomous navigation controller in guiding agricultural vehicles to follow straight paths and turn at the headland.Results showed that an appropriate turn pattern was automatically executed when finishing straight-line navigation.The lateral error in straight-line tracking was no more than 6 cm,6 cm and 5 cm for the rice transplanter,the high-clearance sprayer and the tractor,respectively.And the maximum lateral RMS error was 3.10 cm,4.75 cm,2.21 cm in terms of straight-line tracking,which indicated that the newly developed autonomous navigation controller was versatile and of high robustness in guiding various agricultural vehicles.

Predicting geogenic groundwater fluoride contamination throughout China

Endemic fluorosis exists in almost all provinces of China.The long-term ingestion of groundwater containing high concentrations of fluoride is one of the main causes of fluoro-sis.We used artificial neural network to model the relationship between groundwater fluo-ride concentrations from throughout China and environmental variables such as climatic,geological.and soil parameters as proxy predictors.The results show that the accuracy and area under the receiver operating characteristic curve of the model in the test dataset are 80.5%and 0.86%,respectively,and climatic variables are the most effective predictors.Based on the artificial neural network model,a nationwide prediction risk map of fluoride concen-trations exceeding 1.5 mg/L with a 0.5×0.5 arc minutes resolution was generated.The high risk areas are mainly located in western provinces of Xinjiang,Tibet,Qinghai,and Sichuan,and the northern provinces of Inner Mongolia,Hebei and Shandong.The total number of people estimated to be potentially at risk of fluorosis due to the use of untreated high flu-oride groundwater as drinking water is about 89 million,or 6%of the population.The high fluoride groundwater risk map helps the authorities to prioritize areas requiring mitigation measures and thus facilitates the implementation of water improvement and defluorida-tion projects.

Advances in graphene oxide membranes for water treatment

Graphene oxide(GO),a derivative of graphene,is a novel carbon material that has attracted a lot of attention in the field of membrane materials as its ability to achieve layer-by-layer stacking and the formation of nanochannels between the lamellae makes it excellent for selective separation of substances.In this paper,the separation mechanism of the GO membrane is summarized.According to the different separation substances,the separation mechanism of graphene oxide membrane is reviewed from two aspects of metal ions and organic pollutants.Next,the preparation methods of graphene oxide membranes is introduced,such as spin-coating,vacuum filtration,dip-coating,spraying,and layer-by-layer self-assembly,followed by a review on the structural regulation of GO.Finally,this paper concludes with an overview of the potential development prospects and challenges of GO membranes.

Chlorobenzenes Contamination in Soils/Sediments at a Site of Decommissioned Plant in Central China

China is one of the most important producers and suppliers of the chlorobenzenes （CBs）, accounting for more than 50% of the world production. Although CBs contamination at the sites of chemical production factories is well-known, the knowledge on spatial distribution and contaminated degree of CBs are still limited. To better understand the occurrence of CBs, a total of 161 soil/sediment samples were collected from 36 sampling points within a 20 m deep from a site of decommissioned chlorobenzenes-producing factory in Wuhan City, Hubei Province, central China. The results showed that monochlorobenzene （MCB） is the predominant contaminants with the ∑CBs levels ranging from 0.05 to 8 600 mg/kg dry weight （dw） with a mean value of 384 mg/kg dw. The vertical distribution of CBs indicated that CBs may have clearly transported to deeper sections in the subsurface. Statistical analyses showed that there are no good correlations between the ∑CBs concentration with soil organic matter （SOM） content and the moisture content.

Preparation and properties of a new porous ceramic material used in clean energy field

At high tem perature, the oxide redox reactions of ceria can split H2O and CO2 to produce H2 and CO, so porous ceria with high temperature resistance and high specific surface area has an important foreground in clean energy applications. In this work, a reticulated porous ceria ceramic material with interconnected porous structure was prepared by the impregnation technique using organic polyurethane sponges as template. The influences of pretreated sponge, dipping time length, pore size and sintering temperature on the porosity and strength of the porous ceria ceramics were system atically studied. With the increasing sintering temperature, the glass phase occurred and led to an increase in strength, but an decrease in porosity. Eventually, we analyzed the relationships betw een porosity and strength of these porous materials, aiming to provide theoretical and practical references for its application in clean-energy field.

Notes for a History of Gas Geochemistry

During ancient times,human interest in naturally-occurring gases was religious,while it was scientific in the historical age and industrial in modern times.Gases were also utilized for practical purposes and more than 3000 years before present day,Chinese populations made use of methane for salt extraction while in the 17th century it was observed that native Americans ignited methane seepages.The development of human thinking on gases followed the fundamental steps that characterized the natural sciences during the 18th century scientific revolution that was based on significant improvements in analytical methods.These improvements are still ongoing while present-day scientific publications evidence the spread of the field of interest and more cooperation with geophysical sciences to solve common interest problems.The existence of proper meetings and dedicated scientific journals confirms that gas geochemistry has ended this pioneering phase to enter a more mature condition.

Leaching Behavior of Trace Elements in Coal Spoils from Yangquan Coal Mine, Northern China

The long-term dumping of coal waste piles has caused serious environmental problems. Release of trace elements（including rare earth elements, REEs） from coal spoils gobs was investigated at Yangquan coal mine, Shanxi Province, China. X-ray diffraction（XRD） was used to analyze the mineral composition of the coal spoils. The minerals of the coal-spoil samples are mainly kaolinite and quartz, with a minor proportion of pyrite. The batch and column tests were employed to simulate the leaching behavior of trace elements from coal spoils. Elements V, Cr, Zn, As, Pb, and Cd are highly enriched in all coal spoils. The coal spoils also have elevated levels of Ga, Ge, Se, Sn, Hf, and Th. The leachate of coal spoils, fried coal spoils and CSFGM（coal spoils fire gas mineral） samples are acidic, with the p H values ranging between 3.0 and 6.6. The released elements with high concentrations（over 100 μg/L） include Fe, Mn, Co, Ni and Zn, while moderately-released elements are Cu, Se, Mo and As. A high content of heavy metals in batch-test leachate with CSFGM indicates an increased mobility of heavy metals in coal spoil combustion byproduct. Within the first hour washing with the electrolyte solution, a rapid rise of common cations, trace elements, and REEs content, as well as a drop of p H value, in effluent was observed. An increased leaching velocity favors the release of trace elements from coal spoils. In addition, the pulse input of precipitation led to more elements to be released than continuous leaching.