Blue Nevus Hidden within the Nevus of Ota

A 3-year-old boy presented with bluish patch and scattered blue spots on the left side of his face.After several sessions of laser treatment,the azury patch in the periorbital area became even darker.Histopathology showed many bipolar,pigment-laden dendritic cells scattered in the papillary and upper reticular dermis.Immunohistochemically,these cells were positive for S100,SOX-10,melan-A,P16,and HMB-45.The positive rate of Ki-67 was less than 5%.Finally,the lesion was diagnosed with nevus of Ota concurrent with common blue nevus.Therefore,for cases of the nevus of Ota with poor response to laser treatment,the possible coexisting diseases should be suspected.

Effects of Q-Switched Laser Treatments on Acquired Bilateral Nevus of Ota-Like Macules: A Retrospective Comparative Study

Objective:Q-switched lasers,including 1064-nm Nd:YAG nansecond laser (QSNYL),755-nm alexandrite nanosecond laser (QSAL),and 694-nm nanosecond ruby laser (QSRL),are clinically available for the treatment of acquired bilateral nevus of Ota-like macules (ABNOM).However,no reliable evidence from large-scale comparative studies identifies which type of laser works best.This study aims to determine the differences in the effectiveness,complications,and risk factors of QSNYL,QSAL,and QSRL in the treatment of ABNOM,further to provide evidence for clinician to make optimal choice according to the condition of patients.Methods:We collected the data from 685 ABNOM patients,including clinical features,medical treatments,and follow-up,since 1999 to 2014.The Kruskal-Wallis test was used to compare therapeutic differences between the three groups.The risk factors were analyzed using univariate analysis (x2 test) and multivariate logistic regression analysis.Results:The overall treatment efficiency of the QSNYL group (52.5%) and QSAL group (51.9%) was higher than that of the QSRL group (39.5%) (x2 =17.468,P < 0.001).The onset time of the QSRL and QSAL groups was shorter than that of the QSNYL group.The factors influencing efficacy in the QSNYL group were age at first treatment,number of treatments,coexistence with melesma,and the presence of hyperpigmentation;in the QSAL group was the number of treatments;and in the QSRL group was the number of treatments and hyperpigmentation.The prevalence of hyperpigrnentation in the QSNYL group (30.5%) and the QSAL group (27.5%) was lower than that of the QSRL group (47.3%) (X2=6.576,P<0.001).Concluslon:The QSNYL,QSAL,and QSRL are all effective and safe treatments for ABNOM.Considering the overall efficacy,duration of treatment,side effects,and risk factors,the QSAL is an optimal choice for ABNOM treatment.

Acne Vulgaris Significantly Lowers the Self-Concept of Girls in Junior High School: A Prospective Cross-Sectional Study

Objective: To evaluate the self-concept level of female students with acne vulgaris in junior high school and the relevant influencing factors. Methods: A total of 598 students in Grade 7 at two junior high schools in Nantong City, Jiangsu Province, China were sampled by cluster sampling method, and divided into two groups: the acne group and the healthy control. Both groups were surveyed using a self-designed demographic questionnaire, and the self-concept level was determined using the six-dimensional Piers-Harris Children's Self-Concept Scale (PHCSS). The differences were compared between two groups using Chi-square test, non-parametric test, and multiple regression analysis. Results: We released a total of 598 questionnaires, and 576 valid questionnaires were received, including 267 in the acne group and 309 in the healthy group. The subscale score of the popularity dimension of the PHCSS in the acne group (8.89±1.780) was significantly lower than that in the healthy group (9.45±1.78, P<0.01). When only the girls were considered, compared with the healthy group, the acne group had a significantly lower total PHCSS score (58.72 ±12.15 vs. 61.47±11.14, P<0.05) and significantly lower subscale scores for physical appearance and attributes (6.68±3.26 vs. 7.97±3.30, P<0.05), happiness and satisfaction (7.70±1.85 vs. 8.12±1.47, P<0.05), and popularity (8.69±1.82 vs. 9.84±1.67, P<0.01). Furthermore, multiple regression analysis revealed the girls' relationship with their parents and classmates, and the paternal educational background showed a significantly impact on the self-consciousness of the acne girls. Conclusion: Acne vulgaris significantly lowers the self-concept of girls in junior high school. The factors influencing the PHCSS scores of girls with acne were the relationship with parents and classmates, and the paternal educational background.