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3D Localization for Multiple AUVs in Anchor-Free Environments by Exploring the Use of Depth Information
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作者 yichen li Wenbin Yu Xinping Guan 《IEEE/CAA Journal of Automatica Sinica》 SCIE EI CSCD 2024年第4期1051-1053,共3页
Dear Editor,This letter investigates the cooperative localization problem for multiple autonomous underwater vehicles(AUVs)in underwater anchor-free environments,where AUV localization errors grow without bound due to... Dear Editor,This letter investigates the cooperative localization problem for multiple autonomous underwater vehicles(AUVs)in underwater anchor-free environments,where AUV localization errors grow without bound due to the accumulated errors in inertial measurements(termed accumulated errors hereafter)and the lack of anchors(with known positions). 展开更多
关键词 AUVS UNDERWATER hereafter
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Current-Aided Multiple-AUV Cooperative Localization and Target Tracking in Anchor-Free Environments 被引量:1
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作者 yichen li Wenbin Yu Xinping Guan 《IEEE/CAA Journal of Automatica Sinica》 SCIE EI CSCD 2023年第3期792-806,共15页
In anchor-free environments,where no devices with known positions are available,the error growth of autonomous underwater vehicle(AUV)localization and target tracking is unbounded due to the lack of references and the... In anchor-free environments,where no devices with known positions are available,the error growth of autonomous underwater vehicle(AUV)localization and target tracking is unbounded due to the lack of references and the accumulated errors in inertial measurements.This paper aims to improve the localization and tracking accuracy by involving current information as extra references.We first integrate current measurements and maps with belief propagation and design a distributed current-aided message-passing scheme that theoretically solves the localization and tracking problems.Based on this scheme,we propose particle-based cooperative localization and target tracking algorithms,named CaCL and CaTT,respectively.In AUV localization,CaCL uses the current measurements to correct the predicted and transmitted position information and alleviates the impact of the accumulated errors in inertial measurements.With target tracking,the current maps are applied in CaTT to modify the position prediction of the target which is calculated through historical estimates.The effectiveness and robustness of the proposed methods are validated through various simulations by comparisons with alternative methods under different trajectories and current conditions. 展开更多
关键词 Anchor-free belief propagation cooperative localization current-aided target tracking
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What leads to readers' satisfaction with the mobile news apps service? An investigation into the roles of content originality and user experience 被引量:1
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作者 Wenjing HE Xiaoyu CHEN +1 位作者 yichen li Yueyi QIU 《Chinese Journal of Library and Information Science》 2015年第3期76-89,共14页
Purpose: This study aims to explore whether content originality and user experience have positive effects on online news readers’ satisfaction with the mobile apps service.Design/methodology/approach: Data was collec... Purpose: This study aims to explore whether content originality and user experience have positive effects on online news readers’ satisfaction with the mobile apps service.Design/methodology/approach: Data was collected via a Web-based survey. Data analysis of this study can be divided into two stages. In the first stage, a descriptive statistical analysis was conducted based on a sample of 612 respondents. In the second stage, the correlation among content originality, user experience and satisfaction was analyzed based on a sample of 377 mobile news apps users. Findings: Results of the first stage showed that social media and mobile news apps were the most important tools for users to access news, and different types of media were playing complementary roles in information transmission. Users held a positive attitude toward their mobile news reading experience and they described news they read on mobile apps with such words as "interesting", "instant", "positive", "profound", and "ironic". Results of the second stage confirmed our hypothesis that content originality and user experience both had positive impacts on user satisfaction.Research limitations: The questionnaires were distributed entirely online, so the sample may not be representative of the general population being studied and thus undermine the reliability and generalization of the findings to some extent. Moreover, this study adopted only one method(survey) and more methods such as interviews can be used to improve the accuracy of the results.Practical implications: The findings of this study can not only provide insights into a better understanding of users’ mobile reading behavior, but also help mobile information service providers attract more users.Originality/value: This is one of the first studies to explore the effects of content originality and user experience on online news readers’ satisfaction with the mobile apps service. 展开更多
关键词 Mobile reading News reading Mobile apps Content or
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Magnesium metal and its corrosion products:Promising materials for tumor interventional therapy 被引量:1
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作者 Binghui Xu Yuna Song +4 位作者 Kairan Yang yichen li Bendong Chen Xia liao Qingan Jia 《Journal of Magnesium and Alloys》 SCIE EI CAS CSCD 2023年第3期763-775,共13页
Magnesium is generally known to degrade in aqueous environments by an electrochemical reaction.The corrosion products of magnesium include hydrogen gas,Mg^(2+),and Mg(OH)_(2).Here,we summarize the published literature... Magnesium is generally known to degrade in aqueous environments by an electrochemical reaction.The corrosion products of magnesium include hydrogen gas,Mg^(2+),and Mg(OH)_(2).Here,we summarize the published literature describing the corrosion characteristics of magnesium,and the antitumor properties of magnesium-associated corrosion products,aiming to induce the therapeutic properties of magnesium and magnesium alloys in solid tumors.The therapeutic potential of corrosion products of magnesium is enormous.Hydrogen gas exhibits antioxidant and anti-inflammatory properties,which amount to potential anti-tumor characteristics.Mg(OH)_(2),which creates a localized alkaline microenvironment,represents a second approach for anti-tumor therapy with magnesium metal.Upregulated concentrations of Mg^(2+)ions in the local tumor microenvironment remodelling are considered a third approach for anti-tumor therapy.Therefore,we speculate about the different physical forms of magnesium that could create an anti-tumor microenvironment upon tumor interventional therapy,a technique that precisely places anti-tumor implants like particles and stents.Finally,we present our viewpoints on the potential use of magnesium in diverse solid tumor therapies to inhibit tumor progression. 展开更多
关键词 MAGNESIUM Hydrogen gas Mg(OH)_(2) Mg^(2+) CANCER Interventional therapy
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DNA methylation mediated by RdDM pathway and demethylation affects furanone accumulation through regulation of QUINONE OXIDOREDUCTASE in strawberry 被引量:1
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作者 Yunduan li Yanna Shi +9 位作者 yichen li Jiao Lu Yunfan Sun Yuanyuan Zhang Wenbo Chen Xiaofang Yang Donald Grierson Zhaobo Lang Guihua Jiang Kunsong Chen 《Horticulture Research》 SCIE CSCD 2023年第8期170-182,共13页
Recently,increasing evidence suggests that DNA methylation plays a crucial role in fruit ripening.However,the role of DNA methylation in regulating specific traits,such as flavor,remains unclear.Here,we report a role ... Recently,increasing evidence suggests that DNA methylation plays a crucial role in fruit ripening.However,the role of DNA methylation in regulating specific traits,such as flavor,remains unclear.Here,we report a role of DNA methylation in affecting furanone biosynthesis in strawberry.Strawberry quinone oxidoreductase(FaQR)is a key enzyme in furanone biosynthesis.There are four FaQR homologs in strawberry cultivar‘Yuexin’,and one of them,FaQR3,contributes∼50%of FaQR transcripts,indicating a major role of FaQR3 in furanone biosynthesis.Through characterization of levels of DNA methylation and FaQR3 transcript and furanone contents during fruit ripening and after the application of DNA methylation inhibitor,we found that the DNA methylation level of the FaQR3 promoter was negatively correlated with FaQR3 expression and furanone accumulation,suggesting that DNA methylation may be involved in furanone biosynthesis through adjusting FaQR3 expression,and responded to different temperatures consistently.In addition,transient expression of a gene in the RNA-directed DNA methylation(RdDM)pathway,FaAGO4,and enrichment analysis of the 24-nucleotide siRNAs suggested that DNA methylation in the FaQR3 promoter is mediated by the RdDM pathway.Transient RNA interference(RNAi)of FaDML indicated that the demethylation pathway may be involved in regulating furanone accumulation.These findings provide new insights into the role of DNA methylation and demethylation in affecting flavor quality in strawberry during fruit ripening. 展开更多
关键词 STRAW FURAN transient
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Solid particle size characterization by a high-frequency collision response in pneumatic particulate flow
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作者 Kai Wang yichen li +5 位作者 Ziang Chang Min Qin Guangming Fu Bangtang Yin Gang Wang jiaqi Tian 《Particuology》 SCIE EI CAS CSCD 2024年第3期39-54,共16页
A novel triaxial vibration method is developed for the real-time characterization of the solid particle size distribution(PsD)in pneumatic particulate flow,which is critical for chemical industry.In this work,the part... A novel triaxial vibration method is developed for the real-time characterization of the solid particle size distribution(PsD)in pneumatic particulate flow,which is critical for chemical industry.In this work,the particle-wall collision and friction behaviours were analysed by the time-domain statistical and timefrequency joint methods to narrow the high-frequency response range by the initial experiment of free fall for a single particle,interparticle,and multiple particles.Subsequently,verification experiments of PSD characterization in pneumatic flow were performed.First,the quantitative triaxial energy response model that considers the particle size,shape,and mass factors were established.Second,a good agreement of the particle number identification was found between the triaxial vibration energy and mean particle size of 150-550μm.Moreover,the performance with the best accuracy was focused on a range of 42-43 kHz in the x-axis and z-axis and 36.8-38.8 kHz in the y-axis.Finally,the individual particle energy was inversely analysed by the triaxial vibration response within the optimized frequency bands,and the PSD was characterized in real-time by a low error rate,that is,5.2% from the XZ-axis direction of sand(42-43 kHz)and 5.6% from the XYZ-axis of glass(30.9-33.9 kHz,46.2-47.2 kHz,38.3-41.3 kHz for each axis response).Therefore,this research complements the existing approaches for PsD characterization in particulate multiphase flow. 展开更多
关键词 Solid particulate flow Triaxial vibration High-frequency response Particle wall Particle size distribution
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Natural gas consumption forecasting model based on coal-to-gas project in China 被引量:4
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作者 Zhiqiang Wang yichen li +1 位作者 Zhanjun Feng Kai Wen 《Global Energy Interconnection》 2019年第5期430-436,共7页
Natural gas is widely used because it is environmentally friendly,particularly in reducing carbon emission and improving the Air Quality Index(AQI)around densely populated cities.China has initiated a coal-to-gas proj... Natural gas is widely used because it is environmentally friendly,particularly in reducing carbon emission and improving the Air Quality Index(AQI)around densely populated cities.China has initiated a coal-to-gas project(CGP)to improve the air quality in northern China.As a subcompany of China National Petroleum Corporation,PetroChina Natural Gas Marketing North Company has been focusing on natural gas resource allocation while considering numerous issues such as ensuring the bottom line of livelihood requirements in winter and the performance of economic indicators for an entire calendar year in the northern part of China.Therefore,the accurate prediction of natural gas consumption is important to PetroChina Natural Gas Marketing North Company.It has become a challenge to forecast natural gas consumption because the natural gas market has changed considerably because of the CGP.Natural gas consumption cannot be forecasted using conventional models.This study analyzes the characteristics of the CGP based on the data obtained from rural individual users and company users.Based on the analysis,the gas consumption in winter is predicted using two different forecasting approaches.The methods presented in this paper provide a basis for formulating effective measures for natural gas scheduling in the northern part of China. 展开更多
关键词 Natural gas Coal to gas project CGP Gas consumption forecasting End user consumption characteristics
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Secreted LRPAP1 binds and triggers IFNAR1 degradation to facilitate virus evasion from cellular innate immunity 被引量:2
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作者 Huangcan li Xiong Wang +5 位作者 Yiran Wang yichen li Ying Chen Yin-Ting Wong Jufang He Ming-liang He 《Signal Transduction and Targeted Therapy》 SCIE CSCD 2023年第10期5046-5058,共13页
variety of ways to antagonize host defense through eliminating IFN-signaling intracellularly for decades.However,the way by viruses target IFN-signaling extracellularly has not been discovered.Infection by both corona... variety of ways to antagonize host defense through eliminating IFN-signaling intracellularly for decades.However,the way by viruses target IFN-signaling extracellularly has not been discovered.Infection by both coronavirus SARS-CoV-2 and enterovirus 71(EV71 or EV-A71)can cause severe diseases such as neurological disorders and even death in children. 展开更多
关键词 IMMUNITY DISEASES eliminating
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An integrative protocol for one‑step PCR amplicon library construction and accurate demultiplexing of pooled sequencing data 被引量:1
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作者 Jiahao Ni Jiao Pan +7 位作者 Yaohai Wang Tianhao Chen Xinshi Feng yichen li Tongtong lin Michael Lynch Hongan Long Weiyi li 《Marine Life Science & Technology》 SCIE CSCD 2023年第4期564-572,共9页
High-throughput sequencing of amplicons has been widely used to precisely and efficiently identify species compositions and analyze community structures,greatly promoting biological studies involving large amounts of ... High-throughput sequencing of amplicons has been widely used to precisely and efficiently identify species compositions and analyze community structures,greatly promoting biological studies involving large amounts of complex samples,especially those involving environmental and pathogen-monitoring ones.Commercial library preparation kits for amplicon sequencing,which generally require multiple steps,including adapter ligation and indexing,are expensive and time-consuming,especially for applications at a large scale.To overcome these limitations,a“one-step PCR approach”has been previously proposed for constructions of amplicon libraries using long fusion primers.However,efficient amplifications of target genes and accurate demultiplexing of pooled sequencing data remain to be addressed.To tackle these,we present an integrative protocol for one-step PCR amplicon library construction(OSPALC).High-quality reads have been generated by this approach to reliably identify species compositions of mock bacterial communities and environmental samples.With this protocol,the amplicon library is constructed through one regular PCR with long primers,and the total cost per DNA/cDNA sample decreases to just 7%of the typical cost via the multi-step PCR approach.Empirically tested primers and optimized PCR conditions to construct OSPALC libraries for 16S rDNA V4 regions are demonstrated as a case study.Tools to design primers targeting at any genomic regions are also presented.In principle,OSPALC can be readily applied to construct amplicon libraries of any target genes using DNA or RNA samples,and will facilitate research in numerous fields. 展开更多
关键词 Amplicon library preparation Lab-made protocol Long-primer PCR Cost efficiency
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类施主效应调控与高择优取向织构提升n型Bi_(2)(Te,Se)_(3)材料热电性能
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作者 李奕辰 白树林 +13 位作者 文熠 赵哲 王磊 刘世博 郑俊卿 王斯琦 刘姗 高德政 刘东锐 朱英才 曹茜 高翔 谢鸿耀 赵立东 《Science Bulletin》 SCIE EI CAS CSCD 2024年第11期1728-1737,共10页
Thermoelectric materials have a wide range of application because they can be directly used in refrigeration and power generation. And the Bi_(2)Te_(3) stand out because of its excellent thermoelectric performance and... Thermoelectric materials have a wide range of application because they can be directly used in refrigeration and power generation. And the Bi_(2)Te_(3) stand out because of its excellent thermoelectric performance and are used in commercial thermoelectric devices. However, n-type Bi_(2)Te_(3) has seriously hindered the development of Bi_(2)Te_(3)-based thermoelectric devices due to its weak mechanical properties and inferior thermoelectric performance. Therefore, it is urgent to develop a high-performance n-type Bi_(2)Te_(3) polycrystalline. In this work, we employed interstitial Cu and the hot deformation process to optimize the thermoelectric properties of Bi_(2)Te_(2.7)Se_(0.3), and a high-performance thermoelectric module was fabricated based on this material. Our combined theoretical and experimental effort indicates that the interstitial Cu reduce the defect density in the matrix and suppresses the donor-like effect, leading to a lattice plainification effect in the material. In addition, the two-step hot deformation process significantly improves the preferred orientation of the material and boosts the mobility. As a result, a maximum ZT of 1.27 at 373 K and a remarkable high ZT_(ave) of 1.22 across the temperature range of 300–425 K are obtained. The thermoelectric generator(TEG, 7-pair) and thermoelectric cooling(TEC, 127-pair) modules were fabricated with our n-type textured Cu_(0.01)Bi_(2)Te_(2.7)Se_(0.3) coupled with commercial p-type Bi_(2)Te_(3). The TEC module demonstrates superior cooling efficiency compared with the commercial Bi_(2)Te_(3) device, achieving a ΔT of 65 and 83.4 K when the hot end temperature at 300 and 350 K, respectively. In addition, the TEG module attains an impressive conversion efficiency of 6.5% at a ΔT of 225 K, which is almost the highest value among the reported Bi_(2)Te_(3)-based TEG modules. 展开更多
关键词 Bi_(2)Te_(3) Texture engineering TEC TEG Donor-like effect
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Vortex excites unidirectional water waves near ancient Luoyang Bridge
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作者 yichen li Xinhua Hu 《Frontiers of physics》 SCIE CSCD 2024年第3期163-165,共3页
Since the discovery of generalized Snell’s law in 2011[1],metasurfaces have opened up the mainstream of arbitrary wavefront manipulation in electromagnetism.Using a gradient-index metasurface,the parallel wavenumber ... Since the discovery of generalized Snell’s law in 2011[1],metasurfaces have opened up the mainstream of arbitrary wavefront manipulation in electromagnetism.Using a gradient-index metasurface,the parallel wavenumber kx of reflected wave can be not equal to the incident one(kx=ξ+k0sinθi,where k0 andθi are the incident wavenumber and angle,andξis the phase gradient of metasurface in its supercell)[1].Whenξ>k0,the reflected wave becomes a surface wave bounded on the metasurface(where|kx|>k0,kz is imaginary,and z is normal to the metasurface)[2].However,as research of metasurfaces continually evolves,some articles have pointed out that such graded metasurfaces suffer from a series of problems[3-6].In particular,multiple metallic resonators are adopted in a subwavelength supercell,resulting in impedance mismatch,moderate conversion efficiency,wave absorption,and fabrication complexity.Hence,although the approach of graded metasurfaces has been demonstrated in the microwave regime,it is hard to extend to infrared and optical ranges with shorter wavelengths.To solve this problem,Ra’di et al.[7]devised metagratings with periodic arrays of bianisotropic scatterers and showed that they enable wave front engineering with unitary efficiency and significantly lower fabrication demands. 展开更多
关键词 GRADED reflected imaginary
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Altered gut microbiome in FUT2 loss-of-function mutants in support of personalized medicine for inflammatory bowel diseases
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作者 Sijing Cheng Jun Hu +10 位作者 Xianrui Wu Ji-An Pan Na Jiao yichen li Yibo Huang Xutao lin Yifeng Zou Yuan Chen lixin Zhu Min Zhi Ping Lan 《Journal of Genetics and Genomics》 SCIE CAS CSCD 2021年第9期771-780,共10页
The FUT2 loss-of-function mutations are highly prevalent and are associated with inflammatory bowel disease(IBD).To investigate the impact of FUT2 loss-of-function mutation on the gut microbiota in patients with IBD,8... The FUT2 loss-of-function mutations are highly prevalent and are associated with inflammatory bowel disease(IBD).To investigate the impact of FUT2 loss-of-function mutation on the gut microbiota in patients with IBD,81 endoscopically confirmed IBD patients were genotyped and divided into 3 groups:homozygous for functional FUT2 genes(SeSe),with one copy of non-functional FUT2 gene(Sese),or homozygous for non-functional FUT2 genes(sese).Escherichia,which attaches to fucosylated glycoconjugates,was the only abundant genus exhibiting decreased abundance in sese patients.Compared with SeSe or Sese patients,sese patients exhibited higher abundance in CD8+inducing Alistipe and Phascolarctobacterium and Th17 inducing Erysipelotrichaceae UCG-003.Counter-intuitively,butyrate-producing bacteria were more abundant in sese patients.Consistently,metabolomics analysis found higher levels of butyrate in sese patients.Our data support the hypothesis that FUT2 loss-of-function mutation participates in the IBD pathogenesis by decreasing binding sites for adherent bacteria and thus altering the gut microbiota.Decreased abundances of adherent bacteria may allow the overgrowth of bacteria that induce inflammatory T cells,leading to intestinal inflammation.As FUT2 loss-of-function mutations are highly prevalent,the identification of T cell inducing bacteria in sese patients could be valuable for the development of personalized microbial intervention for IBD. 展开更多
关键词 FUT2 Inflammatory bowel diseases Crohn’s disease Ulcerative colitis Secretor
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JUNO sensitivity on proton decay p→νK^(+)searches 被引量:1
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作者 Angel Abusleme Thomas Adam +608 位作者 Shakeel Ahmad Rizwan Ahmed Sebastiano Aiello Muhammad Akram 安丰鹏 安琪 Giuseppe Andronico Nikolay Anfimov Vito Antonelli Tatiana Antoshkina Burin Asavapibhop João Pedro Athayde Marcondes de André Didier Auguste Nikita Balashov Wander Baldini Andrea Barresi Davide Basilico Eric Baussan Marco Bellato Antonio Bergnoli Thilo Birkenfeld Sylvie Blin David Blum Simon Blyth Anastasia Bolshakova Mathieu Bongrand Clément Bordereau Dominique Breton Augusto Brigatti Riccardo Brugnera Riccardo Bruno Antonio Budano Mario Buscemi Jose Busto Ilya Butorov Anatael Cabrera Barbara Caccianiga 蔡浩 蔡啸 蔡严克 蔡志岩 Riccardo Callegari Antonio Cammi Agustin Campeny 曹传亚 曹国富 曹俊 Rossella Caruso Cédric Cerna 常劲帆 Yun Chang 陈平平 Po-An Chen 陈少敏 陈旭荣 Yi-Wen Chen 陈义学 陈羽 陈长 程捷 程雅苹 Alexey Chetverikov Davide Chiesa Pietro Chimenti Artem Chukanov Gérard Claverie Catia Clementi Barbara Clerbaux Selma Conforti Di Lorenzo Daniele Corti Flavio Dal Corso Olivia Dalager Christophe De La Taille 邓智 邓子艳 Wilfried Depnering Marco Diaz Xuefeng Ding 丁雅韵 Bayu Dirgantara Sergey Dmitrievsky Tadeas Dohnal Dmitry Dolzhikov Georgy Donchenko 董建蒙 Evgeny Doroshkevich Marcos Dracos Frédéric Druillole 杜然 杜书先 Stefano Dusini Martin Dvorak Timo Enqvist Heike Enzmann Andrea Fabbri Ulrike Fahrendholz 范东华 樊磊 方建 方文兴 Marco Fargetta Dmitry Fedoseev li-Cheng Feng 冯启春 Richard Ford Amélie Fournier 甘浩男 Feng Gao Alberto Garfagnini Arsenii Gavrikov Marco Giammarchi Agnese Giaz Nunzio Giudice Maxim Gonchar 龚光华 宫辉 Yuri Gornushkin Alexandre Göttel Marco Grassi Christian Grewing Vasily Gromov 顾旻皓 谷肖飞 古宇 关梦云 Nunzio Guardone Maria Gul 郭聪 郭竞渊 郭万磊 郭新恒 郭宇航 Paul Hackspacher Caren Hagner 韩然 Yang Han Muhammad Sohaib Hassan 何苗 何伟 Tobias Heinz Patrick Hellmuth 衡月昆 Rafael Herrera 贺远强 侯少静 Yee Hsiung Bei-Zhen Hu 胡航 胡健润 胡俊 胡守扬 胡涛 胡宇翔 胡焯钧 黄春豪 黄桂鸿 黄翰雄 黄文昊 黄鑫 黄性涛 黄永波 惠加琪 霍雷 霍文驹 Cédric Huss Safeer Hussain Ara Ioannisian Roberto Isocrate Beatrice Jelmini Kuo-Lun Jen Ignacio Jeria 季筱璐 吉星曌 贾慧慧 贾俊基 蹇司玉 蒋荻 蒋炜 江晓山 金如意 荆小平 Cécile Jollet Jari Joutsenvaara Sirichok Jungthawan Leonidas Kalousis Philipp Kampmann 康丽 Rebin Karaparambil Narine Kazarian Amina Khatun Khanchai Khosonthongkee Denis Korablev Konstantin Kouzakov Alexey Krasnoperov Andre Kruth Nikolay Kutovskiy Pasi Kuusiniemi Tobias Lachenmaier Cecilia Landini Sébastien Leblanc Victor Lebrin Frederic Lefevre 雷瑞庭 Rupert Leitner Jason Leung 李德民 李飞 李福乐 李高嵩 李海涛 李慧玲 李佳褀 李梦朝 李民 李楠 李楠 李清江 李茹慧 黎山峰 李涛 李卫东 李卫国 李笑梅 李小男 李兴隆 李仪 李依宸 李玉峰 李兆涵 李志兵 李紫源 梁浩 梁昊 廖佳军 Daniel liebau Ayut limphirat Sukit limpijumnong Guey-lin lin 林盛鑫 林韬 凌家杰 Ivano lippi 刘芳 刘海东 刘宏邦 刘红娟 刘洪涛 刘绘 刘江来 刘金昌 刘敏 刘倩 刘钦 Runxuan liu 刘双雨 刘树彬 刘术林 刘小伟 刘熙文 刘言 刘云哲 Alexey Lokhov Paolo Lombardi Claudio Lombardo Kai Loo 陆川 路浩奇 陆景彬 吕军光 路书祥 卢晓旭 Bayarto Lubsandorzhiev Sultim Lubsandorzhiev livia Ludhova Arslan Lukanov 罗凤蛟 罗光 罗朋威 罗舒 罗武鸣 Vladimir Lyashuk 马帮争 马秋梅 马斯 马骁妍 马续波 Jihane Maalmi Yury Malyshkin Roberto Carlos Mandujano Fabio Mantovani Francesco Manzali 冒鑫 冒亚军 Stefano M.Mari Filippo Marini Sadia Marium Cristina Martellini Gisele Martin-Chassard Agnese Martini Matthias Mayer Davit Mayilyan Ints Mednieks 孟月 Anselmo Meregaglia Emanuela Meroni David Meyhöfer Mauro Mezzetto Jonathan Miller lino Miramonti Paolo Montini Michele Montuschi Axel Müller Massimiliano Nastasi Dmitry V.Naumov Elena Naumova Diana Navas-Nicolas Igor Nemchenok Minh Thuan Nguyen Thi 宁飞鹏 宁哲 Hiroshi Nunokawa Lothar Oberauer Juan Pedro Ochoa-Ricoux Alexander Olshevskiy Domizia Orestano Fausto Ortica Rainer Othegraven Alessandro Paoloni Sergio Parmeggiano 裴亚田 Nicomede Pelliccia 彭安国 彭海平 Frédéric Perrot Pierre-Alexandre Petitjean Fabrizio Petrucci Oliver Pilarczyk Luis Felipe Piñeres Rico Artyom Popov Pascal Poussot Wathan Pratumwan Ezio Previtali 齐法制 祁鸣 钱森 钱小辉 钱圳 乔浩 秦中华 丘寿康 Muhammad Usman Rajput Gioacchino Ranucci Neill Raper Alessandra Re Henning Rebber Abdel Rebii 任斌 任杰 Barbara Ricci Mariam Rifai Markus Robens Mathieu Roche Narongkiat Rodphai Aldo Romani Bedřich Roskovec Christian Roth 阮向东 阮锡超 Saroj Rujirawat Arseniy Rybnikov Andrey Sadovsky Paolo Saggese Simone Sanfilippo Anut Sangka Nuanwan Sanguansak Utane Sawangwit Julia Sawatzki Fatma Sawy Michaela Schever Cédric Schwab Konstantin Schweizer Alexandr Selyunin Andrea Serafini Giulio Settanta Mariangela Settimo 邵壮 Vladislav Sharov Arina Shaydurova 石京燕 史娅楠 Vitaly Shutov Andrey Sidorenkov FedorŠimkovic Chiara Sirignano Jaruchit Siripak Monica Sisti Maciej Slupecki Mikhail Smirnov Oleg Smirnov Thiago Sogo-Bezerra Sergey Sokolov Julanan Songwadhana Boonrucksar Soonthornthum Albert Sotnikov OndřejŠrámek Warintorn Sreethawong Achim Stahl Luca Stanco Konstantin Stankevich DušanŠtefánik Hans Steiger Jochen Steinmann Tobias Sterr Matthias Raphael Stock Virginia Strati Alexander Studenikin 孙世峰 孙希磊 孙勇杰 孙永昭 Narumon Suwonjandee Michal Szelezniak 唐健 唐强 唐泉 唐晓 Alexander Tietzsch Igor Tkachev Tomas Tmej Marco Danilo Claudio Torri Konstantin Treskov Andrea Triossi Giancarlo Troni Wladyslaw Trzaska Cristina Tuve Nikita Ushakov Johannes van den Boom Stefan van Waasen Guillaume Vanroyen Vadim Vedin Giuseppe Verde Maxim Vialkov Benoit Viaud Cornelius Moritz Vollbrecht Cristina Volpe Vit Vorobel Dmitriy Voronin Lucia Votano Pablo Walker 王彩申 Chung-Hsiang Wang 王恩 王国利 王坚 王俊 王坤宇 汪璐 王美芬 王孟 王萌 王瑞光 王思广 王维 王为 王文帅 王玺 王湘粤 王仰夫 王耀光 王义 王忆 王贻芳 王元清 王玉漫 王喆 王铮 王志民 王综轶 Muhammad Waqas Apimook Watcharangkool 韦良红 魏微 韦雯露 魏亚东 温凯乐 温良剑 Christopher Wiebusch Steven Chan-Fai Wong Bjoern Wonsak 吴帝儒 吴群 吴智 Michael Wurm Jacques Wurtz Christian Wysotzki 习宇飞 夏冬梅 Xiang Xiao 谢小川 谢宇广 谢章权 邢志忠 续本达 徐程 徐东莲 徐繁荣 许杭锟 徐吉磊 徐晶 徐美杭 徐音Yu Xu 闫保军 Taylor Yan 闫文奇 严雄波 Yupeng Yan 杨安波 杨长根 杨成峰 杨欢 杨洁 杨雷 杨晓宇 杨翊凡 Yifan Yang 姚海峰 Zafar Yasin 叶佳璇 叶梅 叶子平 Ugur Yegin Frédéric Yermia 易培淮 尹娜 尹翔伟 尤郑昀 俞伯祥 余炽业 喻纯旭 余泓钊 于淼 于向辉 于泽源 于泽众 袁成卓 袁影 袁振雄 岳保彪 Noman Zafar Andre Zambanini Vitalii Zavadskyi 曾珊 曾婷轩 曾裕达 占亮 张爱强 张飞洋 张国庆 张海琼 张宏浩 张家梁 张家文 张杰 张金 张景波 张金楠 张鹏 张清民 张石其 张澍 张涛 张晓梅 张鑫 张玄同 张学尧 张岩 张银鸿 张易于 张永鹏 张宇 张圆圆 张玉美 张振宇 张志坚 赵凤仪 赵洁 赵荣 赵书俊 赵天池 郑冬琴 郑华 郑阳恒 钟伟荣 周静 周莉 周楠 周顺 周彤 周详 朱江 朱康甫 朱科军 朱志航 庄博 庄红林 宗亮 邹佳恒 JUNO Collaboration 《Chinese Physics C》 SCIE CAS CSCD 2023年第11期7-22,共16页
The Jiangmen Underground Neutrino Observatory(JUNO)is a large liquid scintillator detector designed to explore many topics in fundamental physics.In this study,the potential of searching for proton decay in the p→νK... The Jiangmen Underground Neutrino Observatory(JUNO)is a large liquid scintillator detector designed to explore many topics in fundamental physics.In this study,the potential of searching for proton decay in the p→νK^(+)mode with JUNO is investigated.The kaon and its decay particles feature a clear three-fold coincidence signature that results in a high efficiency for identification.Moreover,the excellent energy resolution of JUNO permits suppression of the sizable background caused by other delayed signals.Based on these advantages,the detection efficiency for the proton decay via p→νK^(+)is 36.9%±4.9%with a background level of 0.2±0.05(syst)±0.2(stat)events after 10 years of data collection.The estimated sensitivity based on 200 kton-years of exposure is 9.6×1033 years,which is competitive with the current best limits on the proton lifetime in this channel and complements the use of different detection technologies. 展开更多
关键词 proton decay grand unified theories JUNO liquid scintillator detector
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Novel HDAC5-interacting motifs of Tbx3 are essential for the suppression of E-cadherin expression and for the promotion of metastasis in hepatocellular carcinoma 被引量:3
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作者 liang Dong Qi Dong +8 位作者 Ying Chen yichen li Bao Zhang Fanghang Zhou Xiaoming Lyu George GChen Paul Lai Hsiang-fu Kung Ming-liang He 《Signal Transduction and Targeted Therapy》 SCIE 2018年第1期107-117,共11页
Tbx3,a transcriptional repressor,is essential in the organogenesis of vertebrates,stem cell self-renewal and differentiation,and the carcinogenesis of multiple tumor types.However,the mechanism by which Tbx3 participa... Tbx3,a transcriptional repressor,is essential in the organogenesis of vertebrates,stem cell self-renewal and differentiation,and the carcinogenesis of multiple tumor types.However,the mechanism by which Tbx3 participates in the metastasis of hepatocellular carcinoma(HCC)remains largely unknown.In this study,we show that Tbx3 was dramatically upregulated in clinical HCC samples and that elevated expression of Tbx3 promoted cancer progression.To determine the underlying mechanism,systematic glycine scan mutagenesis and deletion assays were performed.We identified two critical motifs,^(585)LFSYPYT^(591)and^(604)HRH^(606),that contribute to the repression of transcriptional activity.These motifs are also essential for Tbx3 to promote cell migration and metastasis both in vitro and in vivo via the suppression of E-cadherin expression.More importantly,Tbx3 directly interacts with HDAC5 via these motifs,and an HDAC inhibitor blocks Tbx3-mediated cell migration and the downregulation of E-cadherin in HCC.As Tbx3 is involved in the carcinogenesis of multiple types of human cancers,our findings suggest an important target for anticancer drug development. 展开更多
关键词 METASTASIS HEPATOCELLULAR Tbx3
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A leakage particle-wall impingement based vibro-acoustic characterization of the leaked sand-gas pipe flow 被引量:1
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作者 Kai Wang Yinan Hu +3 位作者 Min Qin Gang liu yichen li Gang Wang 《Particuology》 SCIE EI CAS CSCD 2021年第2期84-93,共10页
Solid particle leakage detection in double-wall pipes is industrially important,especially in chemical and petroleum engineering.Here,we developed vibration and acoustic sensor approaches for the characterization and ... Solid particle leakage detection in double-wall pipes is industrially important,especially in chemical and petroleum engineering.Here,we developed vibration and acoustic sensor approaches for the characterization and comparative study of the applicability of leakage sand particle detection from the flow of gas pipes.A specific wideband vibration sensor and pressure-field microphone were selected to identify the vibro-acoustic characteristics within 50 kHz of the particle leakage.The vibro-acoustic time-behaviours and characteristic frequencies of particle leakage were observed by the time-frequency method.The leakage gas flow noise was verified by coherence analysis and minimized by a digital bandpass and band-elimination filter.Corresponding experiments were performed,and good agreement was found between the release pressures(0.1-0.3 MPa)with different leak sizes(0-8 mm)under different sand masses(120μm)and vibro-acoustic Root-Mean-Square(RMS)levels.In the comparison of the two methods,the vibration method has a better frequency response for the leakage flow and is good for identifying whether there are particle leaks.The acoustic method has a time behaviour response and is good for establishing the relationship between the particle mass and signals.In addition,the acoustic method has frequency shift features with a better signal to noise ratio.The acoustic method lays the foundation for future work of more complex leakage detection combining the advantages of vibration and the acoustic method. 展开更多
关键词 Solid particle detection Vibration and acoustic Sand-gas flow Pipe leak
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SARS-CoV-2 impairs the disassembly of stress granules and promotes ALS-associated amyloid aggregation 被引量:1
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作者 yichen li Shuaiyao Lu +12 位作者 Jinge Gu Wencheng Xia Shengnan Zhang Shenqing Zhang Yan Wang Chong Zhang Yunpeng Sun Jian Lei Cong liu Zhaoming Su Juntao Yang Xiaozhong Peng Dan li 《Protein & Cell》 SCIE CSCD 2022年第8期602-614,共13页
The nucleocapsid(N)protein of SARS-CoV-2 has been reported to have a high ability of liquid-liquid phase separation,which enables its incorporation into stress granules(SGs)of host cells.However,whether SG invasion by... The nucleocapsid(N)protein of SARS-CoV-2 has been reported to have a high ability of liquid-liquid phase separation,which enables its incorporation into stress granules(SGs)of host cells.However,whether SG invasion by N protein occurs in the scenario of SARS-CoV-2 infection is unknow,neither do we know its con-sequence.Here,we used SARS-CoV-2 to infect mam-malian cells and observed the incorporation of N protein into SGs,which resulted in markedly impaired self-dis-assembly but stimulated cell cellular clearance of SGs.NMR experiments further showed that N protein binds to the SG-related amyloid proteins via non-specific tran-sient interactions,which not only expedites the phase transition of these proteins to aberrant amyloid aggre-gation in vitro,but also promotes the aggregation of FUS with ALS-associated P525L mutation in cells.In addition,we found that ACE2 is not necessary for the infection of SARS-CoV-2 to mammalian cells.Our work indicates that SARS-CoV-2 infection can impair the dis-assembly of host SGs and promote the aggregation of SG-related amyloid proteins,which may lead to an increased risk of neurodegeneration. 展开更多
关键词 SARS-CoV-2 nucleocapsid protein stress granule
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Comparative WGBS identifies genes that influence non-ripe phenotype in tomato epimutant Colourless non-ripening 被引量:3
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作者 Weiwei Chen Zhiming Yu +11 位作者 Junhua Kong Hui Wang yichen li Mei Zhao Xiaohong Wang Qianqian Zheng Nongnong Shi Pengcheng Zhang Silin Zhong Paul Hunter Mahmut Tor Yiguo Hong 《Science China(Life Sciences)》 SCIE CAS CSCD 2018年第2期244-252,共9页
Whole-genome bisulfite sequencing(WGBS)allows single-base resolution and genome-wide profiling of DNA methylation in plants and animals.This technology provides a powerful tool to identify genes that are potentially c... Whole-genome bisulfite sequencing(WGBS)allows single-base resolution and genome-wide profiling of DNA methylation in plants and animals.This technology provides a powerful tool to identify genes that are potentially controlled by dynamic changes of DNA methylation and demethylation.However,naturally occurring epimutants are rare and genes under epigenetic regulation as well as their biological relevances are often difficult to define.In tomato,fruit development and ripening are a complex process that involves epigenetic control.We have taken the advantage of the tomato epimutant Colourless non-ripening(Cnr)and performed comparative mining of the WGBS datasets for the Cnr and Sl CMT3-silenced Cnr fruits.We compared DNA methylation profiles for the promoter sequences of approximately 5,000 bp immediately upstream of the coding region of a list of20 genes.Differentially methylated regions were found for some of these genes.Virus-induced gene silencing(VIGS)of differentially methylated gene Sl DET1 or Sl PDS resulted in unusual brown pigmentation in Cnr fruits.These results suggest that comparative WGBS coupled with VIGS can be used to identify genes that may contribute to the colourless unripe phenotype of fruit in the Cnr epimutant. 展开更多
关键词 tomato Cnr SlCMT3 SlDET1 SlPDS DNA methylation WGBS VIGS
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Sub-percent precision measurement of neutrino oscillation parameters with JUNO
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作者 Angel Abusleme Thomas Adam +601 位作者 Shakeel Ahmad Rizwan Ahmed Sebastiano Aiello Muhammad Akram Abid Aleem Fengpeng An Qi An Giuseppe Andronico Nikolay Anfimov Vito Antonelli Tatiana Antoshkina Burin Asavapibhop João Pedro Athayde Marcondes de André Didier Auguste Weidong Bai Nikita Balashov Wander Baldini Andrea Barresi Davide Basilico Eric Baussan Marco Bellato Antonio Bergnoli Thilo Birkenfeld Sylvie Blin David Blum Simon Blyth Anastasia Bolshakova Mathieu Bongrand Clément Bordereau Dominique Breton Augusto Brigatti Riccardo Brugnera Riccardo Bruno Antonio Budano Jose Busto Ilya Butorov Anatael Cabrera Barbara Caccianiga Hao Cai Xiao Cai Yanke Cai Zhiyan Cai Riccardo Callegari Antonio Cammi Agustin Campeny Chuanya Cao Guofu Cao Jun Cao Rossella Caruso Cédric Cerna Chi Chan Jinfan Chang Yun Chang Guoming Chen Pingping Chen Po-An Chen Shaomin Chen Xurong Chen Yixue Chen Yu Chen Zhiyuan Chen Zikang Chen Jie Cheng Yaping Cheng Yu Chin Cheng Alexey Chetverikov Davide Chiesa Pietro Chimenti Artem Chukanov Gérard Claverie Catia Clementi Barbara Clerbaux Selma Conforti Di Lorenzo Daniele Corti Flavio Dal Corso Olivia Dalager Christophe De La Taille Zhi Deng Ziyan Deng Wilfried Depnering Marco Diaz Xuefeng Ding Yayun Ding Bayu Dirgantara Sergey Dmitrievsky Tadeas Dohnal Dmitry Dolzhikov Georgy Donchenko Jianmeng Dong Evgeny Doroshkevich Marcos Dracos Frédéric Druillole Ran Du Shuxian Du Stefano Dusini Martin Dvorak Timo Enqvist Heike Enzmann Andrea Fabbri Donghua Fan Lei Fan Jian Fang Wenxing Fang Marco Fargetta Dmitry Fedoseev Zhengyong Fei li-Cheng Feng Qichun Feng Richard Ford Amélie Fournier Haonan Gan Feng Gao Alberto Garfagnini Arsenii Gavrikov Marco Giammarchi Nunzio Giudice Maxim Gonchar Guanghua Gong Hui Gong Yuri Gornushkin Alexandre Göttel Marco Grassi Vasily Gromov Minghao Gu Xiaofei Gu Yu Gu Mengyun Guan Yuduo Guan Nunzio Guardone Cong Guo Jingyuan Guo Wanlei Guo Xinheng Guo Yuhang Guo Paul Hackspacher Caren Hagner Ran Han Yang Han Miao He Wei He Tobias Heinz Patrick Hellmuth Yuekun Heng Rafael Herrera YuenKeung Hor Shaojing Hou Yee Hsiung Bei-Zhen Hu Hang Hu Jianrun Hu Jun Hu Shouyang Hu Tao Hu Yuxiang Hu Zhuojun Hu Guihong Huang Hanxiong Huang Kaixuan Huang Wenhao Huang Xin Huang Xingtao Huang Yongbo Huang Jiaqi Hui Lei Huo Wenju Huo Cédric Huss Safeer Hussain Ara Ioannisian Roberto Isocrate Beatrice Jelmini Ignacio Jeria Xiaolu Ji Huihui Jia Junji Jia Siyu Jian Di Jiang Wei Jiang Xiaoshan Jiang Xiaoping Jing Cécile Jollet Jari Joutsenvaara Leonidas Kalousis Philipp Kampmann li Kang Rebin Karaparambil Narine Kazarian Amina Khatun Khanchai Khosonthongkee Denis Korablev Konstantin Kouzakov Alexey Krasnoperov Nikolay Kutovskiy Pasi Kuusiniemi Tobias Lachenmaier Cecilia Landini Sébastien Leblanc Victor Lebrin Frederic Lefevre Ruiting Lei Rupert Leitner Jason Leung Daozheng li Demin li Fei li Fule li Gaosong li Huiling li Mengzhao li Min li Nan li Nan li Qingjiang li Ruhui li Rui li Shanfeng li Tao li Teng li Weidong li Weiguo li Xiaomei li Xiaonan li Xinglong li Yi li yichen li Yufeng li Zepeng li Zhaohan li Zhibing li Ziyuan li Zonghai li Hao liang Hao liang Jiajun liao Ayut limphirat Guey-lin lin Shengxin lin Tao lin Jiajie ling Ivano lippi Fang liu Haidong liu Haotian liu Hongbang liu Hongjuan liu Hongtao liu Hui liu Jianglai liu Jinchang liu Min liu Qian liu Qin liu Runxuan liu Shubin liu Shulin liu Xiaowei liu Xiwen liu Yan liu Yunzhe liu Alexey Lokhov Paolo Lombardi Claudio Lombardo Kai Loo Chuan Lu Haoqi Lu Jingbin Lu Junguang Lu Shuxiang Lu Bayarto Lubsandorzhiev Sultim Lubsandorzhiev livia Ludhova Arslan Lukanov Daibin Luo Fengjiao Luo Guang Luo Shu Luo Wuming Luo Xiaojie Luo Vladimir Lyashuk Bangzheng Ma Bing Ma Qiumei Ma Si Ma Xiaoyan Ma Xubo Ma Jihane Maalmi Jingyu Mai Yury Malyshkin Roberto Carlos Mandujano Fabio Mantovani Francesco Manzali Xin Mao Yajun Mao Stefano M.Mari Filippo Marini Cristina Martellini Gisele Martin-Chassard Agnese Martini Matthias Mayer Davit Mayilyan Ints Mednieks Artur Meinusch Yue Meng Anselmo Meregaglia Emanuela Meroni David Meyhö Mauro Mezzetto Jonathan Miller lino Miramonti Marta Colomer Molla Paolo Montini Michele Montuschi Axel Müller Massimiliano Nastasi Dmitry V.Naumov Elena Naumova Diana Navas-Nicolas Igor Nemchenok Minh Thuan Nguyen Thi Feipeng Ning Zhe Ning Hiroshi Nunokawa Lothar Oberauer Juan Pedro Ochoa-Ricoux Alexander Olshevskiy Domizia Orestano Fausto Ortica Rainer Othegraven Alessandro Paoloni Sergio Parmeggiano Yatian Pei Luca Pelicci Nicomede Pelliccia Anguo Peng Haiping Peng Yu Peng Zhaoyuan Peng Frédéric Perrot Pierre-Alexandre Petitjean Fabrizio Petrucci Oliver Pilarczyk Luis Felipe Piñeres Artyom Popov Pascal Poussot Ezio Previtali Fazhi Qi Ming Qi Sen Qian Xiaohui Qian Zhen Qian Hao Qiao Zhonghua Qin Shoukang Qiu Gioacchino Ranucci Neill Raper Reem Rasheed Alessandra Re Henning Rebber Abdel Rebii Mariia Redchuk Bin Ren Jie Ren Barbara Ricci Mariam Rifai Mathieu Roche Narongkiat Rodphai Aldo Romani Bedřich Roskovec Xichao Ruan Arseniy Rybnikov Andrey Sadovsky Paolo Saggese Simone Sanfilippo Anut Sangka Utane Sawangwit Julia Sawatzki Michaela Schever Cédric Schwab Konstantin Schweizer Alexandr Selyunin Andrea Serafini Giulio Settanta Mariangela Settimo Zhuang Shao Vladislav Sharov Arina Shaydurova Jingyan Shi Yanan Shi Vitaly Shutov Andrey Sidorenkov FedorŠimkovic Chiara Sirignano Jaruchit Siripak Monica Sisti Maciej Slupecki Mikhail Smirnov Oleg Smirnov Thiago Sogo-Bezerra Sergey Sokolov Julanan Songwadhana Boonrucksar Soonthornthum Albert Sotnikov OndřejŠrámek Warintorn Sreethawong Achim Stahl Luca Stanco Konstantin Stankevich DušanŠtefánik Hans Steiger Jochen Steinmann Tobias Sterr Matthias Raphael Stock Virginia Strati Alexander Studenikin Jun Su Shifeng Sun Xilei Sun Yongjie Sun Yongzhao Sun Zhengyang Sun Narumon Suwonjandee Michal Szelezniak Jian Tang Qiang Tang Quan Tang Xiao Tang Vidhya Thara Hariharan Eric Theisen Alexander Tietzsch Igor Tkachev Tomas Tmej Marco Danilo Claudio Torri Konstantin Treskov Andrea Triossi Giancarlo Troni Wladyslaw Trzaska Alexandros Tsagkarakis Cristina Tuve Nikita Ushakov Vadim Vedin Giuseppe Verde Maxim Vialkov Benoit Viaud Cornelius Moritz Vollbrecht Cristina Volpe Katharina Von Sturm Vit Vorobel Dmitriy Voronin Lucia Votano Pablo Walker Caishen Wang Chung-Hsiang Wang En Wang Guoli Wang Jian Wang Jun Wang Lu Wang Meifen Wang Meng Wang Meng Wang Ruiguang Wang Siguang Wang Wei Wang Wei Wang Wenshuai Wang Xi Wang Xiangyue Wang Yangfu Wang Yaoguang Wang Yi Wang Yi Wang Yifang Wang Yuanqing Wang Yuman Wang Zhe Wang Zheng Wang Zhimin Wang Zongyi Wang Apimook Watcharangkool Wei Wei Wei Wei Wenlu Wei Yadong Wei Kaile Wen liangjian Wen Christopher Wiebusch Steven Chan-Fai Wong Bjoern Wonsak Diru Wu Qun Wu Zhi Wu Michael Wurm Jacques Wurtz Christian Wysotzki Yufei Xi Dongmei Xia Xiang Xiao Xiaochuan Xie Yuguang Xie Zhangquan Xie Zhao Xin Zhizhong Xing Benda Xu Cheng Xu Donglian Xu Fanrong Xu Hangkun Xu Jilei Xu Jing Xu Meihang Xu Yin Xu Baojun Yan Taylor Yan Wenqi Yan Xiongbo Yan Yupeng Yan Changgen Yang Chengfeng Yang Huan Yang Jie Yang Lei Yang Xiaoyu Yang Yifan Yang Haifeng Yao Jiaxuan Ye Mei Ye Ziping Ye Frédéric Yermia Na Yin Zhengyun You Boxiang Yu Chiye Yu Chunxu Yu Hongzhao Yu Miao Yu Xianghui Yu Zeyuan Yu Zezhong Yu Cenxi Yuan Chengzhuo Yuan Ying Yuan Zhenxiong Yuan Baobiao Yue Noman Zafar Vitalii Zavadskyi Shan Zeng Tingxuan Zeng Yuda Zeng liang Zhan Aiqiang Zhang Bin Zhang Binting Zhang Feiyang Zhang Guoqing Zhang Honghao Zhang Jialiang Zhang Jiawen Zhang Jie Zhang Jin Zhang Jingbo Zhang Jinnan Zhang Mohan Zhang Peng Zhang Qingmin Zhang Shiqi Zhang Shu Zhang Tao Zhang Xiaomei Zhang Xin Zhang Xuantong Zhang Xueyao Zhang Yinhong Zhang Yiyu Zhang Yongpeng Zhang Yu Zhang Yuanyuan Zhang Yumei Zhang Zhenyu Zhang Zhijian Zhang Fengyi Zhao Jie Zhao Rong Zhao Runze Zhao Shujun Zhao Dongqin Zheng Hua Zheng Yangheng Zheng Weirong Zhong Jing Zhou li Zhou Nan Zhou Shun Zhou Tong Zhou Xiang Zhou Jiang Zhu Jingsen Zhu Kangfu Zhu Kejun Zhu Zhihang Zhu Bo Zhuang Honglin Zhuang liang Zong Jiaheng Zou 《Chinese Physics C》 SCIE CAS CSCD 2022年第12期28-49,共22页
JUNO is a multi-purpose neutrino observatory under construction in the south of China.This publication presents new sensitivity estimates for the measurement of the △m_(31)^(2),△m_(21)^(2),sin^(2)θ_(12),and sin^(2)... JUNO is a multi-purpose neutrino observatory under construction in the south of China.This publication presents new sensitivity estimates for the measurement of the △m_(31)^(2),△m_(21)^(2),sin^(2)θ_(12),and sin^(2)θ_(13) oscillation parameters using reactor antineutrinos,which is one of the primary physics goals of the experiment.The sensitivities are obtained using the best knowledge available to date on the location and overburden of the experimental site,the nuclear reactors in the surrounding area and beyond,the detector response uncertainties,and the reactor antineutrino spectral shape constraints expected from the TAO satellite detector.It is found that the △m_(21)^(2) and sin^(2)θ_(12) oscillation parameters will be determined to 0.5%precision or better in six years of data collection.In the same period,the △m_(31)^(2) parameter will be determined to about 0.2%precision for each mass ordering hypothesis.The new precision represents approximately an order of magnitude improvement over existing constraints for these three parameters. 展开更多
关键词 neutrino oscillation reactor antineutrino precision measurement JUNO
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突发事件紧急医学救援物资配置问题:文献综述与研究展望
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作者 覃朝晖 李亦琛 +4 位作者 陈敬云 许铁 沈良 郑舒遥 燕宪亮 《中华卫生应急电子杂志》 2024年第3期178-182,共5页
近年来,我国公共卫生、事故灾难、自然灾害等重大突发事件高发频发,严重危害公众健康与社会安定。突发事件发生后的紧急医学救援对保障人民生命安全十分重要,可实现最大限度地减少突发事件造成的人员伤亡、降低病死率和伤残率,保障公众... 近年来,我国公共卫生、事故灾难、自然灾害等重大突发事件高发频发,严重危害公众健康与社会安定。突发事件发生后的紧急医学救援对保障人民生命安全十分重要,可实现最大限度地减少突发事件造成的人员伤亡、降低病死率和伤残率,保障公众健康和生命安全、维护社会稳定。其中救援物资的及时供给与合理配置是紧急医学救援工作中的关键环节,优化救援物资的配置管理是高效开展紧急医学救援的基础。例如,新冠疫情全球暴发流行期间,卫生防疫物资的配置问题极为严峻,一定程度上反映出卫生应急物资保障体系的脆弱性,实现供需平衡、精准科学的物资配置是疫情防控的关键。党的二十大报告强调,要提高防灾减灾救灾和重大突发公共事件处置保障能力[1]。国家卫生健康委员会发布的《突发事件紧急医学救援"十四五"规划》(以下简称《规划》)中明确指出加强突发事件紧急医学救援物资仓储配送,提升突发事件紧急医学救援能力[2]。探究紧急医学救援物资配置的过程机制、加快构建有效满足突发事件应对处置需要的紧急医学救援物资配置体系意义重大。因此,笔者针对"突发事件紧急医学救援物资配置"这一主题的相关研究进行梳理与总结并探讨该领域未来的研究主题。 展开更多
关键词 突发事件应对 重大突发公共事件 维护社会稳定 卫生应急 公众健康 疫情防控 人民生命安全 救援物资
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