FAHP在课程思政教学效果评价中的应用

课程思政教学是专业知识与价值塑造的融合,其效果评价是一个多准则决策问题。本文引入模糊层次分析法(Fuzzy Analytic Hierarchy Process,FAHP)探究课程思政教学效果,完成思政融入课堂后教学效果的多因素综合评价,为提升思政课程的教学质量提供科学依据。首先,定义课程思政教学效果的评价指标体系,包括3个一级指标和10个二级指标;其次,运用FAHP对各指标进行权重赋值并分析模糊关系;最后进行实证分析,得出各指标的得分及综合评价结果。实践证明:评价模型具有一定普适性,通过思政指标和专业知识能力指标一体化构建,对课程思政教学效果进行较全面的评价。同时,可以通过试验找到最适合的β值,用以改变指标权重,能够进一步提高方案的区分度。

Effect of Zhuang Medicine Feilongzhangxue on the Expression of HMGB1-TLR4 / RANKL-NF-κB Signaling Pathway Related Factors in Osteoclasts

Objective:To study the regulatory effect of feilongzhangxue on the levels of HMGB1-TLR4/RANKL-NF-κB signaling pathway related factors HMGB1,RANKL,rank,TRAF-6 and NF-κBp65 in osteoclasts,so as to explore the mechanism of feilongzhangxue intervention in RA;Methods:The osteoclasts with good activity were randomly divided into blank group,methotrexate control group and Zhuang medicine feilongzhang blood containing serum treatment group,which were divided into OC+blank group,OC+methotrexate control group,OC+Zhuang medicine feilongzhang blood containing serum group;The expression of HMGB1,RANKL,rank,TRAF-6 and NF-κBp65 mRNA was detected by RT-PCR;The protein expressions of HMGB1,RANKL,RANK,TRAF-6 and NF-κBp65 were detected by immunofluorescence.Results:PCR results showed that:Compared with the blank group,feilongzhangxue could effectively inhibit the expression levels of HMGB1,RANKL,rank,TRAF-6 and NF-κB p65 mRNA in OC cells,and the inhibitory effect was stronger than methotrexate.Immunofluorescence test results showed that:Compared with the blank group and methotrexate group,feilongzhangxue could effectively inhibit the protein expression of HMGB1,RANKL,rank,TRAF-6 and NF-κB p65 in OC cells.Conclusion:The effect of Zhuang medicine feilongzhangxue on hmgbl-tlr4/rankl-nf-κB signaling pathway of osteoclasts is through the regulation of related factors HMGB1,RANKL,rank,TRAF-6 and NF-κB p65,which may be the key mechanism of Zhuang medicine feilongzhangxue on rheumatoid arthritis.

Recovery of Li, Ni, Co and Mn from spent lithium-ion batteries assisted by organic acids: Process optimization and leaching mechanism

The proper recycling of spent lithium-ion batteries(LIBs)can promote the recovery and utilization of valuable resources,while also negative environmental effects resulting from the presence of toxic and hazardous substances.In this study,a new environmentally friendly hydro-metallurgical process was proposed for leaching lithium(Li),nickel(Ni),cobalt(Co),and manganese(Mn)from spent LIBs using sulfuric acid with citric acid as a reductant.The effects of the concentration of sulfuric acid,the leaching temperature,the leaching time,the solid-liquid ratio,and the reducing agent dosage on the leaching behavior of the above elements were investigated.Key parameters were optimized using response surface methodology(RSM)to maximize the recovery of metals from spent LIBs.The maxim-um recovery efficiencies of Li,Ni,Co,and Mn can reach 99.08%,98.76%,98.33%,and 97.63%.under the optimized conditions(the sulfuric acid concentration was 1.16 mol/L,the citric acid dosage was 15wt%,the solid-liquid ratio was 40 g/L,and the temperature was 83℃ for 120 min),respectively.It was found that in the collaborative leaching process of sulfuric acid and citric acid,the citric acid initially provided strong reducing CO_(2)^(-),and the transition metal ions in the high state underwent a reduction reaction to produce transition metal ions in the low state.Additionally,citric acid can also act as a proton donor and chelate with lower-priced transition metal ions,thus speeding up the dissolution process.

Sabatier principle guiding the design of cathode catalysts for Li-CO_(2) batteries

The Sabatier principle has been widely used for designing electrocatalysts for energy conversion applications,but it is rarely mentioned in the research of cathode catalyst of Li-CO_(2) batteries.In our work,the"volcanic"relationship between the catalytic activity and the adsorption energy of the catalyst to the intermediates is first demonstrated based on the first-principles calculation,which meets the Sabatier principle and can be used to design the cathode catalysts.The increases in the number of nitrogenvacancy in WN shift the d-band center and increase the interaction with the reactants.The catalytic activity increases first and then decreases with the increase of adsorption energy,which was proved in the experiment.The optimal catalyst for moderate adsorption of intermediate makes the thin LiaCO_(3) distribute evenly.It exhibits a median voltage difference of 0.68 V and an energy efficiency of 84.33%at20μA cm^(-2)with a limited capacity of 200μA h cm^(-2).

Prevalence of physical fitness in Chinese school-aged children： Findings from the 2016 Physical Activity and Fitness in China -The Youth Study

Purpose： This study was to present the 2016 prevalence estimates of Chinese school-aged children meeting physical fitness standards and to examine differences by sex and residence locales in children who did not meet fitness standards. Methods： We conducted cross-sectional analyses of 171,991 children and adolescents （boy： 50.0%, Grades 1-12） who participated in the 2016 Physical Activity and Fitness in China--The Youth Study. The main outcomes were fitness measures, assessed by the 2014 revised Chinese National Student Physical Fitness Standard （CNSPFS）, covering areas of aerobic capacity, upper body strength, flexibility, body mass index, abdominal strength, and trunk strength. Children＇s overall physical fitness performance was categorized, per CNSPFS standards, as excellent, good, pass, or no pass. Data on the prevalence of physical fitness categories and not meeting fitness standards （i.e., among children who received a ＂no pass＂ mark） were analyzed, through logistic regression, by sex （boy, girl） and residence locales （urban, rural） across 3 school grades （primary, junior middle, and junior high）. Results： In 2016, 5.95% of Chinese children and adolescents achieved an ＂excellent＂ mark, 25.80% received a ＂good＂ rating, 59.90% received a ＂pass＂, and 8.35% received a ＂no pass＂. Overall, boys were more likely to not pass the fitness standards compared with girls （adjusted odds ratio （aOR） = 1.710; 95% confidence interval （CI）： 1.708-1.712） and children living in urban areas were more likely to not pass the standards than those living in rural areas （aOR = 1.298; 95%CI： 1.296-1.299）. Consistent patterns of not meeting fitness standards were also found by sex and residence locales across all 3 school grades. Conclusion： In the Chinese school-aged population, about 3 in 10 children achieved an ＂excellent＂ or ＂good＂ fitness standard in 2016, and about 8% of this population did not meet CNSPFS standards. Children living in urban areas were more likely to not meet minimum fitness performance levels, and boys in school were more likely to not meet minimum fitness performance levels than girls. 2017 Production and hosting by Elsevier B.V. on behalf of Shanghai University of Sport. This is an open access article under the CC BY-NC-ND license （http：//creativecommons.org/licenses/by-nc-nd/4.0/）.

Synergetic strengthening mechanism of ultrasound combined with calcium fluoride towards vanadium extraction from low-grade vanadium-bearing shale

The effect and mechanism of ultrasound and CaF_(2) on vanadium leaching from vanadium-bearing shale were investigated systematically.In consideration of the enhancement for vanadium recovery,the combination of ultrasound and CaF_(2)(66.28%) exerts more evident effects than ultrasound(26.97%) and CaF_(2)(60.35%) alone,demonstrating the synergetic effect of ultrasound and CaF_(2).Kinetic analysis manifests that the product layer diffusion controls vanadium leaching in ultrasound system without CaF_(2),however product layer diffusion and interfacial reaction is the rate-controlling step for vanadium leaching in other three leaching systems.The combination of ultrasound and CaF_(2) notably decreases the activation energy(E_(a)) from 62.03 to 27.61 kJ/mol,nevertheless individual CaF_(2) only reduces the E_(a) to 50.70 kj/mol.X-ray diffraction and fourier transform infrared spectrometer analyses show that the decomposition degree of the vanadium-bearing mica structure is the most significant in ultrasound and CaF_(2) system,proving the highest release degree of vanadium.Specific surface area and pore distribution combined with scanning electron microscope analyses reveal that the action of ultrasound and CaF_(2) would provide higher specific surface area,more abundant pores structure and cracks for the particles,which further prompts the rapid diffusion of H^(+),F^(-)and HF,and achieves the conspicuous improvement of vanadium leaching recovery.

Synchronization of two coupled exciters in a vibrating system of spatial motion

The paper proposes an analytical approach to investigate the synchronization of the two coupled exciters in a vibrating system of spatial motion. Introducing the distur- bance parameters for average angular velocity of two excit- ers, we deduce the non-dimensional coupling equations of angular velocities of two exciters, in which the inertia cou- pling matrix is symmetric and the stiffness coupling matrix is antisymmetric in a non-resonant vibrating system. The analysis of the coupling dynamic characteristic shows that the coupled cosine effect of the phase angles will cause the torque acting on two motors to limit the increase of phase difference between two exciters as well as sustain its sym- metry of two exciters during the running process. It physi- cally explains the peculiarity of self-synchronization of two exciters. The cosine effect of phase angles of the vibrations excited by each exciter will decrease its moment of inertia. The residual moment of inertia of each exciter represents its relative moment of inertia. The stability condition of synchro- nization of two exciters is that the relative non-dimensional moments of inertia of two exciters are all greater than zero and four times their product is greater than the square of their coefficient of coupled cosine effect of phase angles, which is equivalent to that the inertia coupling matrix is positive definite and all its elements are positive. The numeric results show that the structure of the vibrating system can ensure the stability condition of synchronous operation.

Adhesion between nanobubbles and fine cassiterite particles

Adhesion is an important process of particle-bubble interaction in fine particle(-10μm)flotation.This paper studied the adhesion process and mechanism between nanobubbles and fine cassiterite particles by using a high-speed camera,atomic force microscope(AFM),adsorption capacity tests,and induction time tests.After being pretreated with nanobubbles(NBs)water,fine cassiterite particles flotation tests were carried out using caprylhydroxamic acid(CHA)as a collector.The results showed that NBs can improve the recovery and flotation rate of fine cassiterite while decreasing the collector dosage.The adsorption capacity test indicated that the cassiterite treated with NBs had lower demand for collector concentration.The AFM imaging results further demonstrate that NBs could reduce the adsorption of CHA on the surface of minerals.Since NBs played a part of the role of collector,it can improve the flotation effect while reducing the amount of collector.The induction time test and the high-speed camera observation test showed that NBs promoted the attachment between bubbles and cassiterite particles.On the other hand,NBs agglomerate cassiterite particles,increasing the probability of particles colliding with bubbles.

An insight on the mechanism of efficient leaching of vanadium from vanadium shale induced by microwave-generated hot spots

Microwave heating can rapidly and uniformly raise the temperature and accelerate the reaction rate.In this paper,microwave heating was used to improve the acid leaching,and the mechanism was investigated via microscopic morphology analysis and numerical simulation by COMSOL Multiphysics software.The effects of the microwave power,leaching temperature,CaF_(2) dosage,H_(2)SO_(4) concentration,and leaching time on the vanadium recovery were investigated.A vanadium recovery of 80.66%is obtained at a microwave power of 550 W,leaching temperature of 95℃,CaF_(2) dosage of 5wt%,H_(2)SO_(4) concentration of 20vol%,and leaching time of 2.5 h.Compared with conventional leaching technology,the vanadium recovery increases by 6.18%,and the leaching time shortens by 79.17%.More obvious pulverization of shale particles and delamination of mica minerals happen in the microwave-assisted leaching process.Numerical simulation results show that the temperature of vanadium shales increases with an increase in electric field(E-field).The distributions of E-field and temperature among vanadium shale particles are relatively uniform,except for the higher content at the contact position of the particles.The analysis results of scaleup experiments and leaching experiments indicate high-temperature hot spots in the process of microwave-assisted leaching,and the local high temperature destroys the mineral structure and accelerates the reaction rate.

A Promising Anti-Cytokine-Storm Targeted Therapy for COVID-19:The Artificial-Liver Blood-Purification System

The coronavirus disease 2019(COVID-19)pan-epidemic,resulting from infection with the 2019 novel coronavirus(2019-nCoV),also known as severe acute respiratory syndrome-coronavirus-2(SARS-CoV-2),is currently the source of public health concern worldwide;however,treatment of this infection has been clinically challenging in many patients[1].Importantly,2019-nCoV is the third fatal coronavirus that has emerged in the past two decades,following SARS-CoV and the Middle East respiratory syndrome(MERS)-CoV[2].The numbers of confirmed cases of COVID-19 infection and related deaths are still rising.As of 9 March 2020.

Low-temperature dry reforming of methane tuned by chemical speciations of active sites on the SiO_(2) and γ-Al_(2)O_(3) supported Ni and Ni-Ce catalysts

The cognition of active sites in the Ni-based catalysts plays a vital role and remains a huge challenge in improving catalytic performance of low temperature CO_(2) dry reforming of methane(LTDRM).In this work,typical catalysts of SiO_(2) and γ-Al_(2)O_(3) supported Ni and Ni-Ce were designed and prepared.Importantly,the difference in the chemical speciations of active sites on the Ni-based catalysts is revealed by advanced characterizations and further estimates respective catalytic performance for LTDRM.Results show that larger[Ni0-]particles mixed with[Ni-O-Sin])species on the Ni/SiO_(2)(R)make CH_(4) excessive decomposition,leading to poor activity and stability.Once the Ce species is doped,however,superior activity(59.0%CH_(4) and 59.8%CO_(2) conversions),stability and high H_(2)/CO ratio(0.96)at 600℃ can be achieved on the Ni-Ce/SiO_(2)(R),in comparison with other catalysts and even reported studies.The improved performance can be ascribed to the formation of integral([Ni0_(n))]-[CeⅢ-□-CeⅢ])species on the Ni-Ce/SiO_(2)(R)catalyst,containing highly dispersed[Ni]particles and rich oxygen vacancies,which can synergistically establish a new stable balance between gasification of carbon species and CO_(2) dissocia-tion.With respect to Ni-Ce/γ-Al_(2)O_(3)(R),the Ni and Ce precursors are easily captured by extra-framework Al_(n)-OH groups and further form stable isolated([Ni0_(n))]-[Ni-O-Al_(n)])and[CeⅢ-O-Al_(n)]species.In such a case,both of them preferentially accelerate CO_(2) adsorption and dissociation,causing more car-bon deposition due to the disproportionation of superfuous CO product.This deep distinguishment of chemical speciations of active sites can guide us to further develop new efficient Ni-based catalysts for LTDRM in the future.

Fabrication of green one-part geopolymer from silica-rich vanadium tailing via thermal activation and modification

The aim of this investigation was to prepare geopolymeric precursor from vanadium tailing(VT)by thermal activation and modification.For activation,a homogeneous blend of VT and sodium hydroxide was calcinated at an elevated temperature and then modified with metakaolin to produce a geopolymeric precursor.During the thermal activation,the VT was corroded by sodium hydroxide and then sodium silicate formed on the particle surfaces.After water was added,the sodium silicate coating dissolved to release silicon species,which created an alkaline solution environment.The metakaolin then dissolved in the alkaline environment to generate aluminum species,which was followed by geopolymerization.The VT particles were connected by a gel produced during geopolymerization,which yielded a geopolymer with excellent mechanical performance.This investigation not only improves the feasibility of using geopolymer technology for large-scale and in-situ applications,but also promotes the utilization of VT and other silica-rich solid wastes.

THE ASYMPTOTIC BEHAVIOR AND SYMMETRY OF POSITIVE SOLUTIONS TO p-LAPLACIAN EQUATIONS IN A HALF-SPACE

We study a nonlinear equation in the half-space with a Hardy potential,specifically,−Δ_(p)u=λu^(p−1)x_(1)^(p)−x_(1)^(θ)f(u)in T,where Δp stands for the p-Laplacian operator defined by Δ_(p)u=div(∣Δu∣^(p−2)Δu),p>1,θ>−p,and T is a half-space{x_(1)>0}.When λ>Θ(where Θ is the Hardy constant),we show that under suitable conditions on f andθ,the equation has a unique positive solution.Moreover,the exact behavior of the unique positive solution as x_(1)→0^(+),and the symmetric property of the positive solution are obtained.

Effect of job satisfaction on burnout among physicians: A survey study in urban public medical institutions in Hubei province, China

Objectives: Chinese physicians are being loaded with the enormous psychological pressure and so tend to be susceptible to burnout. Little is known on the relationship between job satisfaction and burnout for physicians from urban public medical institutions. We aim to describe the degree of burnout and evaluate the impact of job satisfaction on burnout. Methods: A cross-sectional survey was conducted in March 2010 in Hubei province, central China. The job satisfaction and burnout instruments were obtained by modifying the Chinese Physicians’ Job Satisfaction Questionnaire and the Chinese Maslach Burnout Inventory, respectively. Such statistical methods as one-way ANOVA, Pearson correlation coefficient and GLM-univariate were employed. Results: The observed mean and burnout incidence on emotional exhaustion (3.45 ± 0.75, 66.99%) and depersonalization (3.56 ± 0.76, 68.64%) were high, but reduced personal accomplishment (2.18 ± 0.56, 5.79%) was low. The distribution of the degree of overall burnout was: 3.2% (severe), 48.2% (moderate), 35.4% (mild) and 13.2% (zero). Less the development level of urban area and higher the grade of medical institution was, more severe physicians’ burnout was. Job-itself satisfaction (b1 = -0.166, b2 = -0.056), job rewards satisfaction (b1 = -0.084, b2 = -0.150) and medical practicing environment satisfaction (b1 = -0.096, b2 = -0.319) were identified as significant negative predictors of emotional exhaustion (R2 = 0.35) and also of depersonalization (R2 = 0.46). Only the job-itself satisfaction (b3 = -0.355) contributed to reduced personal accomplishment (R2 = 0.40). significantly Conclusions: Occupational burnout, especially emotional exhaustion and depersonalization, is common and serious among Chinese physicians. Several, but not all dimensions of job satisfaction, which prove to have predictive effects on burnout, should be paid more attention to in order to improve physicians’ psychological health.

Influence of bone morphogenetic protein on articular cartilage regeneration following periosteal grafting

Background: Autologous periosteal grafting is used as treatment for articular cartilage defect. Objective: To study the effect of bone morphogenetic protein (BMP) on articular cartilage regeneration following periosteal grafting. Methods: 16 healthy 15 week-old New Zealand white rabbits of both sexes (32 knees) were randomly divided into experimental group (group A) and control group (group B). A4.0 mmdiameter full-thickness articular cartilage defect was created in the femoral intercondylar fossa in all rabbits. Following this, a4.0 mmdiameter section of the periosteum was harvested from the anteromedial part of the upper tibial bone. In group A (eight rabbits, 16 knees), the cartilage defect was covered with periosteum, into which 20 μg BMP and 20% Pluronic were injected. In group B (eight rabbits, 16 knees), the cartilage defect was covered with periosteum, into which the same dosage of 0.9% NS (Normal saline) and 20% Pluronic were injected. All rabbits were sacrificed at 4, 8, and 12 weeks postoperatively, the cartilage defect areas were examined macroscopically and microscopically, and the morphology of the chondrocytes and collagen fibers were examined by scanning electron microscopy. Results: The filling of the defects with regenerated tissue was observed in both the group. The most notable improvement was that the cartilage regeneration in group A was obviously superior to that in group B, with the total histological score in group A significantly higher. Conclusion: BMP is an effective factor that could promote regeneration of articular cartilage and lead to successful cartilaginous resurfacing following periosteal

沈三白与华萼

有收藏爱好者在华夏收藏网上发布了一幅《七夕相会图》,其上题诗落款为“雨堂外史华萼”。而清《浮生六记》的作者沈三白(沈复)的姬人即为华萼。尽管此华萼是否为彼华萼,尚待考订,但当年沈三白佐史琉球,携姬而归,却是他一段出彩的佳话。

Optimized the vanadium electrolyte with sulfate-phosphoric mixed acids to enhance the stable operation at high-temperature

Herein, the influence of the concentration design and comprehensive performance of the sulfate-phosphoric mixed acid system electrolyte is investigated to realize an electrolyte that maintains high energy density and stable operation at high temperatures. Static stability tests have shown that VOPO4 precipitation occurs only with vanadium(V) electrolyte. The concentration of vanadium ion of 2.0–2.2 mol·L^(–1), phosphoric acid of 0.10–0.15 mol·L^(–1), and sulfuric acid of 2.5–3.0 mol·L^(–1) are suitable for a vanadium redox flow battery in the temperature range from –20 to 50 ℃. The equations for predicting the viscosity and conductivity of electrolytes are obtained by the response surface method. The optimized electrolyte overcomes precipitation generation. It has 2.8 times higher energy density than the non-phosphate electrolyte, and a coulomb efficiency of 94.0% at 50 ℃. The sulfate-phosphoric mixed acid system electrolyte promotes the electrode reaction process, increases the current density, and reduces the resistance. This work systematically optimizes the concentrations of composition of positive and negative vanadium electrolytes with mixed sulfate-phosphoric acid. It provides a basis for the different valence states and comprehensive properties of sulfate-phosphoric mixed acid system vanadium electrolytes under extreme environments, guiding engineering applications.

Oxidative mechanism of chicken wooden breast myofibrillar protein

To explore the oxidation mechanism of wooden breast myofibrillar protein(WBMP),oxidative breast MP(OBMP)was obtained from different doses(3,10,and 20 mmol/L)of H2O2 oxidized normal breast MP(NBMP).The results showed that the Zeta-potential,particle size,solubility,sulfhydryl,and carbonyl contents of OBMP-3(3 mmol/L,low-dose free radicals)and WBMP were similar.Fluorescence spectrum analysis showed that the oxidation of low-dose free radicals led to a significant increase in the surface hydrophobicity(from 214.03±10.03 to 393.50±10.33)and tryptophan fluorescence intensity(from 185.71 to 568.32).In addition,theα-helix content of WBMP decreased significantly from(37.46±1.15)%(NBMP)to(34.70±2.04)%,whileβ-sheet and random coil contents increased significantly(P<0.05)from(14.37±0.69)%and(22.24±0.78)%(NBMP)to(17.70±0.87)%and(25.20±1.47)%(WBMP).In summary,low-dose free radical oxidation attacks protein groups,inducing secondary and tertiary structural changes,leading to the formation of WBMP.This work will provide a theoretical basis at the molecular level for exploring the mechanism of functional degradation of WBMP.

Immunomodulatory and Antiviral Therapy Improved Functional Cure Rate in CHB Patients with High HBsAg Level Experienced NA

Background and Aims:A functional cure,or hepatitis B virus(HBV)surface antigen(HBsAg)loss,is difficult to achieve in patients with hepatitis B virus e antigen(HBeAg)-positive chronic hepatitis B.The HBV vaccine and granulocyte-macrophage colony-stimulating factor(GM-CSF)have been reported to help reduce HBsAg levels and promote HBsAg loss.In this prospective randomized trial,we evaluated HBsAg loss in patients receiving pegylated interferon α2b(PEGIFN-α2b)and tenofovir disoproxil fumarate(TDF),with and without GM-CSF and HBV vaccination.Methods:A total of 287 patients with HBeAg positive chronic hepati-tis B and seroconversion after nucleot(s)ide analog treat-ment were assigned randomly to three treatment groups for 48 weeks,TDF alone(control),PEGIFN-α2b+TDF,and PEGIFN-α2b+TDF+GM-CSF+HBV vaccine.The prima-ry endpoints were the proportions of patients with HBsAg loss and seroconversion at 48 and 72 weeks.Resu/ts:The cumulative HBsAg loss rates in the control,PEGIFN-α2b+TDF,and PEGIFN-α2b+TDF+GM-CSF+HBV vaccine groups at week 48 were 0.0%,28.3%,and 41.1%,respec-tively.The cumulative HBsAg seroconversion rates in these groups at week 48 were 0.0%,21.7%,and 33.9%,respec-tively.Multivariate regression analysis showed that GM-CSF use plus HBV vaccination was significantly associated with HBsAg loss(p=0.017)and seroconversion(p=0.030).Con-clusions:In patients with HBeAg-positive chronic hepatitis B and seroconversion after nucleot(s)ide analog treatment,immunomodulatory/antiviral treatment regimens effective-ly improved HBsAg loss,and the regimen including GM-CSF and HBV vaccination was most effective.

Reliability-based robust design optimization of vehicle components, Part Ⅱ： Case studies

The reliability-based optimization, the relia- bility-based sensitivity analysis and robust design method are employed to propose an effective approach for reliability-based robust design optimization of vehicle components in Part I. Applications of the method are further discussed for reliability-based robust optimization of vehicle components in this paper. Examples of axles, torsion bar, coil and composite springs are illustrated for numerical investigations. Results have shown the proposed method is an efficient method for reliability-based robust design optimization of vehicle components.