In order to extract the defect edge information on the magnetic tile surface with low contrast and textured background,an edge detection algorithm based on image weighted information entropy and wavelet modulus maxima...In order to extract the defect edge information on the magnetic tile surface with low contrast and textured background,an edge detection algorithm based on image weighted information entropy and wavelet modulus maxima is proposed.At first,a new Butterworth high pass filter(BHPF) with adaptive cutoff frequency is produced,because the clarity and complexity of the textured background are described by the weighted information entropy of the image gradient variance quantitatively,and the filter can change its parameters through matching the non-linear relationship between the information entropy and the cutoff frequency.And then,the best decomposition scale is obtained by the level determination function to prevent edge information from missing.At last,edge points are got by double threshold after obtaining the wavelet modulus maxima,and then the edge image is linked by the edge points to ensure the edge continuity and veracity.Experiment results indicate that the proposed algorithm outperforms the conventional Canny and Sobel algorithm,and the edge detection algorithm can also detect other defects,and lays the foundation for defecting auto- recognition.展开更多
Radiotherapy combined with chemotherapy and immunotherapy is the development trend of precise cancer treatment.As an advanced radiotherapy method,carbon ion therapy can activate the immune response of cancer cells,and...Radiotherapy combined with chemotherapy and immunotherapy is the development trend of precise cancer treatment.As an advanced radiotherapy method,carbon ion therapy can activate the immune response of cancer cells,and its combination with immunotherapy is expected to further improve the effect of cancer control and improve the survival of cancer patients.In this study,anti-PD-L1,anti-HER-2 and R848 immune antibodies were selected to study the changes of weight and volume of tumors in mice bearing triple negative breast cancer 4T1-4P cells.Anti-HER-2 was further selected in different groups(control group,carbon ion group,immune treatment group and combined treatment group).T cell population analysis was carried out in combination with R848 and carbon ion group.展开更多
基金Supported by the National Natural Science Foundation of China(No.51205265)
文摘In order to extract the defect edge information on the magnetic tile surface with low contrast and textured background,an edge detection algorithm based on image weighted information entropy and wavelet modulus maxima is proposed.At first,a new Butterworth high pass filter(BHPF) with adaptive cutoff frequency is produced,because the clarity and complexity of the textured background are described by the weighted information entropy of the image gradient variance quantitatively,and the filter can change its parameters through matching the non-linear relationship between the information entropy and the cutoff frequency.And then,the best decomposition scale is obtained by the level determination function to prevent edge information from missing.At last,edge points are got by double threshold after obtaining the wavelet modulus maxima,and then the edge image is linked by the edge points to ensure the edge continuity and veracity.Experiment results indicate that the proposed algorithm outperforms the conventional Canny and Sobel algorithm,and the edge detection algorithm can also detect other defects,and lays the foundation for defecting auto- recognition.
文摘Radiotherapy combined with chemotherapy and immunotherapy is the development trend of precise cancer treatment.As an advanced radiotherapy method,carbon ion therapy can activate the immune response of cancer cells,and its combination with immunotherapy is expected to further improve the effect of cancer control and improve the survival of cancer patients.In this study,anti-PD-L1,anti-HER-2 and R848 immune antibodies were selected to study the changes of weight and volume of tumors in mice bearing triple negative breast cancer 4T1-4P cells.Anti-HER-2 was further selected in different groups(control group,carbon ion group,immune treatment group and combined treatment group).T cell population analysis was carried out in combination with R848 and carbon ion group.