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一流课程视域下的高等师范院校有机化学课程建设与实践
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作者 赵勇 毕韵梅 +2 位作者 王利勤 詹睿 黄国利 《大学化学》 CAS 2024年第8期54-63,共10页
为有效提升师范院校有机化学课程教学质量,针对我院有机化学课程建设中存在的问题,基于“学生中心、出口导向、持续改进”理念,从学生学习和教师教学两个层面进行了剖析;并针对性提出问题解决思路,阐述了课程建设实施的“一二八”战略,... 为有效提升师范院校有机化学课程教学质量,针对我院有机化学课程建设中存在的问题,基于“学生中心、出口导向、持续改进”理念,从学生学习和教师教学两个层面进行了剖析;并针对性提出问题解决思路,阐述了课程建设实施的“一二八”战略,构建了特色鲜明、成效显著的有机化学课程教学体系,课程建设取得了明显成效。 展开更多
关键词 有机化学 课程建设 学生中心 “一二八”战略
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水帘结构同步水冷装置对光-粉同路激光熔覆温度场的影响研究
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作者 杨高林 刘谭亮 +4 位作者 雍兆 郑权航 王晓江 石岳林 姚建华 《表面技术》 EI CAS CSCD 北大核心 2024年第13期13-21,共9页
目的解决大型设备激光增材修复过程中的局部升温易烧蚀零件边缘、熔化内部导线及橡胶圈、损坏原有结构的问题。方法采用Fluent软件和VOF模型研究水帘下干区稳定气液两相流模型,通过Abaqus软件和热传导三定律、热弹塑性理论、热变形理论... 目的解决大型设备激光增材修复过程中的局部升温易烧蚀零件边缘、熔化内部导线及橡胶圈、损坏原有结构的问题。方法采用Fluent软件和VOF模型研究水帘下干区稳定气液两相流模型,通过Abaqus软件和热传导三定律、热弹塑性理论、热变形理论建立温度场和弯曲变形的数值模型,并通过对比光-粉同路和同步水冷2种方式下熔覆316L不锈钢的熔池形貌、晶粒尺寸、热量累积、弯曲变形差异,验证同步水冷对熔覆过程中温度场的影响机理。结果同步水冷装置内部水帘呈散射状流向四周,能够形成稳定的干区环境,沉积后的金相表面无明显气孔、裂纹等缺陷。在相同参数单道沉积时,温度云图和熔池形貌表明,水冷有效缩减了熔池的大小,但其对熔池凝固速度的影响较小,二者平均晶粒尺寸仅存在略微差别,分别为28.81μm和27.55μm。多道沉积时,水帘的冷却作用拔高了熔池边缘的温度差异,拉低了外延区域的热量累积,在降低基板整体温度的同时,增大了熔池边缘的温度梯度,而温差的增大带来了更大的热应力,导致不同沉积方式下基板的变形程度不同。在悬臂梁搭接熔覆试验中,采用热电偶测得同步水冷能保持基板背面温度在50℃以下,而光-粉同路最高能达到500℃。同时,悬臂梁厚度较薄时,基板上下面温差产生的热应力大于基板自身约束力,试样发生严重变形,且含同步水冷的变形更为明显。厚度增加时,试样自身约束力增大,变形量差异逐渐减小。结论同步水冷水路的耦合限制了熔池热量的深入与扩散,可以有效实现熔覆过程中加工区域的温度控制,同时也会导致在工件较薄时弯曲变形程度提升,但在板材厚度大于3 mm时,变形量差别趋于相同,且越来越小。 展开更多
关键词 同步水冷 光-粉同路 增材制造 温度控制 能场复合 数值模拟
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Identification of an Aux/IAA regulator for flesh firmness using combined GWAS and bulked segregant RNA-Seq analysis in watermelon 被引量:1
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作者 Muhammad Anees Hongju Zhu +8 位作者 Muhammad Jawad Umer Chengsheng Gong Pingli Yuan Xuqiang Lu Nan He Mohamed Omar Kaseb Dongdong Yang yong zhao Wenge Liu 《Horticultural Plant Journal》 SCIE CAS CSCD 2024年第5期1198-1213,共16页
Watermelon is a highly cultivated fruit crop renowned for its quality properties of fruit flesh.Among various quality factors,fruit flesh firmness is a crucial quality parameter influencing the fruit texture,shelf lif... Watermelon is a highly cultivated fruit crop renowned for its quality properties of fruit flesh.Among various quality factors,fruit flesh firmness is a crucial quality parameter influencing the fruit texture,shelf life and its commercial value.The auxin/indole-3-acetic acid(Aux/IAA)plays a significant role in fruit development and ripening of non-climacteric fruits.However,the regulatory mechanism of Aux/IAA in controlling fruit flesh firmness and ripening in watermelon remains unknown.In this study,we employed an integrative approach combining genome-wide association study(GWAS)and bulked segregant RNA-Seq analysis(BSR-Seq)to identify an overlapping candidate region between 12776310 and 12968331 bp on chromosome 6,underlying an auxin-responsive gene(Aux/IAA)associated with flesh firmness in watermelon.Transcriptome analysis,followed by real-time quantitative reverse transcription PCR(qRT-PCR),confirmed that the expression of Aux/IAA was consistently higher in fruits with high flesh firmness.The sequence alignment revealed a single base mutation in the coding region of Aux/IAA.Furthermore,the concomitant Kompetitive/Competitive allele-specific PCR(KASP)genotyping data sets for F2 population and germplasm accessions identified Aux/IAA as a strong candidate gene associated with flesh firmness.Aux/IAA was enriched in the plant hormone signal transduction pathway,involving cell enlargement and leading to low flesh firmness.We determined the higher accumulation of abscisic acid(ABA)in fruits with low flesh firmness than hard flesh.Moreover,overexpression of Aux/IAA induced higher flesh firmness with an increased number of fruit flesh cells while reducing ABA content and flesh cell sizes.Additionally,the allelic variation in Aux/IAA for soft flesh firmness was found to exist in Citrullus mucosospermus and gradually fixed into Citrullus lanatus during domestication,indicating that soft flesh firmness was a domesticated trait.These findings significantly enhanced our understanding of watermelon fruit flesh firmness and consequently the watermelon fruit quality. 展开更多
关键词 WATERMELON Flesh firmness GWAS BSR-Seq KASP marker analysis Transient overexpression
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Increased dependence on nitrogen-fixation of a native legume in competition with an invasive plant 被引量:1
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作者 Meixu Han Haiyang Zhang +12 位作者 Mingchao Liu Jinqi Tang Xiaocheng Guo Weizheng Ren yong zhao Qingpei Yang Binglin Guo Qinwen Han Yulong Feng Zhipei Feng Honghui Wu Xitian Yang Deliang Kong 《Plant Diversity》 SCIE CAS CSCD 2024年第4期510-518,共9页
Suppression of roots and/or their symbiotic microorganisms,such as mycorrhizal fungi and rhizobia,is an effective way for alien plants to outcompete native plants.However,little is known about how invasive and native ... Suppression of roots and/or their symbiotic microorganisms,such as mycorrhizal fungi and rhizobia,is an effective way for alien plants to outcompete native plants.However,little is known about how invasive and native plants interact with the quantity and activity of nutrient-acquisition agents.Here a pot experiment was conducted with monoculture and mixed plantings of an invasive plant,Xanthium strumarium,and a common native legume,Glycine max.We measured traits related to root and nodule quantity and activity and mycorrhizal colonization.Compared to the monoculture,fine root quantity(biomass,surface area)and activity(root nitrogen(N)concentration,acid phosphatase activity)of G.max decreased in mixed plantings;nodule quantity(biomass)decreased by 45%,while nodule activity in Nfixing via rhizobium increased by 106%;mycorrhizal colonization was unaffected.Contribution of N fixation to leaf N content in G.max increased in the mixed plantings,and this increase was attributed to a decrease in the rhizosphere soil N of G.max in the mixed plantings.Increased root quantity and activity,along with a higher mycorrhizal association was observed in X.strumarium in the mixed compared to monoculture.Together,the invasive plant did not directly scavenge N from nodule-fixed N,but rather depleted the rhizosphere soil N of the legume,thereby stimulating the activity of N-fixation and increasing the dependence of the native legume on this N source.The quantity-activity framework holds promise for future studies on how native legumes respond to alien plant invasions. 展开更多
关键词 Mycorrhizal strategy Nitrogen depletion Plant invasion Root nutrient acquisition strategy Symbiotic nitrogen fixation
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Analysis of explosion wave interactions and rock breaking effects during dual initiation
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作者 Renshu Yang Jinjing Zuo +3 位作者 Liwei Ma yong zhao Zhen Liu Quanmin Xie 《International Journal of Minerals,Metallurgy and Materials》 SCIE EI CAS CSCD 2024年第8期1788-1798,共11页
In blasting engineering, the location and number of detonation points, to a certain degree, regulate the propagation direction ofthe explosion stress wave and blasting effect. Herein, we examine the explosion wave fie... In blasting engineering, the location and number of detonation points, to a certain degree, regulate the propagation direction ofthe explosion stress wave and blasting effect. Herein, we examine the explosion wave field and rock breaking effect in terms of shockwave collision, stress change of the blast hole wall in the collision zone, and crack propagation in the collision zone. The produced shockwave on the collision surface has an intensity surpassing the sum of the intensities of the two colliding explosion shock waves. At the collisionlocation, the kinetic energy is transformed into potential energy with a reduction in particle velocity at the wave front and the wavefront pressure increases. The expansion form of the superposed shock wave is dumbbell-shaped, the shock wave velocity in the collisionarea is greater than the radial shock wave velocity, and the average propagation angle of the explosion shock waves is approximately 60°.Accordingly, a fitted relationship between blast hole wall stress and explosion wave propagation angle in the superposition area is plotted.Under the experimental conditions, the superimposed explosion wave stress of the blast hole wall is approximately 1.73 times the singleexplosionwave incident stress. The results of the model test and numerical simulations reveal that large-scale radial fracture cracks weregenerated on the blast hole wall in the superimposed area, and the width of the crack increased. The width of the large-scale radial fracturecracks formed by a strong impact is approximately 5% of the blast hole length. According to the characteristics of blast hole wallcompression, the mean peak pressures of the strongly superimposed area are approximately 1.48 and 1.84 times those of the weakly superimposedand nonsuperimposed areas, respectively. 展开更多
关键词 BLASTING shock wave collision high-speed schlieren system crack fracture characteristic explosion wave
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Transcriptome Analysis of Inflorescence Development at the Five-Leaf Stage in Castor(Ricinus communis L.)
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作者 yong zhao Yaxuan Jiang +7 位作者 Li Wen Rui Luo Guorui Li Jianjun Di Mingda Yin Zhiyan Wang Fenglan Huang Fanjuan Meng 《Phyton-International Journal of Experimental Botany》 SCIE 2024年第4期713-723,共11页
The yield of castor is influenced by the type of inflorescence and the proportion of female flowers.However,there are few studies on the genetic mechanism involved in the development and differentiation of castor infl... The yield of castor is influenced by the type of inflorescence and the proportion of female flowers.However,there are few studies on the genetic mechanism involved in the development and differentiation of castor inflorescences.In this study,we performed transcriptomic analyses of three different phenotypes of inflorescences at the five-leaf stage.In comparison to the MI(complete pistil without willow leaves),290 and 89 differentially expressed genes(DEGs)were found in the SFI(complete pistil with willow leaves)and the BI(monoecious inflorescence),respectively.Among the DEGs,104 and 88 were upregulated in the SFI and BI,respectively,compared to the MI.In addition,186 DEGs and 1 DEG were downregulated in the SFI and BI compared to the MI.Moreover,we conducted GO and KEGG enrichment analyses of the DEGs.In comparison to the MI,the SFI and BI exhibited the enrichment of functional branches in DEGs,specifically in pollen wall assembly,pollen development,and cellular component assembly involved in morphogenesis.In our study,RADL5 showed low expression levels between SFI-vs.-MI types.In addition,we found that the expression of NAC in the SFI differed from that in MI and BI,and some genes related to hormonal signaling changed their expression levels during inflorescence differentiation.These results reveal the genetic mechanism of sex genotypes in castor,which will not only guide researchers in the breeding of castor but also provide a reference for genetic research on other flowering plants. 展开更多
关键词 Ricinus communis L RNA-SEQ INFLORESCENCE
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Research on the Resistance of Cutting Mechanism of Mining Longitudinal Roadheader
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作者 Mengjiao NIU yong zhao yongliang YUAN 《Mechanical Engineering Science》 2024年第1期8-12,共5页
In order to accurately obtain the dynamic characteristics of the cutting mechanism of the mining longitudinal roadheader,combined with the working principle of the mining longitudinal roadheader,the theoretical analys... In order to accurately obtain the dynamic characteristics of the cutting mechanism of the mining longitudinal roadheader,combined with the working principle of the mining longitudinal roadheader,the theoretical analysis and derivation are carried out in detail.By using ADAMS to simulate,the resistance curve and torque curve of the cutting mechanism in different directions are obtained.The results show that ADAMS can effectively predict the excavation resistance and torque of the cutting mechanism of mining longitudinal roadheader,which has certain reference value for future optimization design. 展开更多
关键词 longitudinal roadheader cutting mechanism dynamic characteristics DYNAMICS
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新疆叶城县维吾尔族6~12岁儿童的近视及远视储备现况 被引量:4
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作者 阿依努·努拉厚 赵勇 +1 位作者 郭宁 高云仙 《国际眼科杂志》 CAS 北大核心 2023年第6期986-990,共5页
目的:了解新疆叶城县维吾尔族6~12岁儿童近视及远视储备现状。方法:采用横断面研究,共有来自新疆叶城县维吾尔族6~12岁的50151名学生均接受了全面的视力筛查检查,其中包括全自动电脑验光仪进行验光、室内远用灯箱式E字标准对数视力表(GB... 目的:了解新疆叶城县维吾尔族6~12岁儿童近视及远视储备现状。方法:采用横断面研究,共有来自新疆叶城县维吾尔族6~12岁的50151名学生均接受了全面的视力筛查检查,其中包括全自动电脑验光仪进行验光、室内远用灯箱式E字标准对数视力表(GB 11533)测裸眼远视力及戴镜矫正视力。结果:2021-10/2022-01新疆叶城县维吾尔族6~12岁近视儿童等效球镜度(SE)为-0.875(-1.625,-0.625)D,近视检出率为6.75%(3384/50151),其中6~12岁近视儿童SE分别为6岁-0.75(-1.125,-0.625)D、7岁-0.75(-1.125,-0.625)D、8岁-0.875(-1.125,-0.625)D、9岁-0.875(-1.375,-0.625)D、10岁-0.875(-1.6,-0.625)D、11岁-0.875(-1.625,-0.625)D、12岁-1.25(-2.125,-0.75)D。6~12岁非近视儿童SE为+0.25(-0.125,+0.5)D,远视储备不足检出率为75.51%,其6~12岁非近视儿童SE分别为6岁+0.25(-0.125,+0.5)D、7岁+0.25(0,+0.5)D、8岁+0.125(-0.125,+0.5)D、9岁+0.25(-0.125,+0.5)D、10岁+0.125(-0.125,+0.5)D、11岁+0.125(-0.125,+0.5)D、12岁+0.25(-0.125,+0.625)D。近视检出率分别为6岁6.78%、7岁5.64%、8岁5.72%、9岁5.36%、10岁5.01%、11岁6.82%、12岁12.14%;非近视远视储备不足检出率分别为6岁91.67%、7岁92.04%、8岁92.91%、9岁83.85%、10岁68.89%、11岁54.01%、12岁26.71%。9~12岁非近视儿童女生远视储备不足检出率高于男生(χ^(2)=8.94、19.99、19.91、39.11,均P<0.05);10~12岁儿童女生近视检出率高于男生(χ^(2)=5.402、8.493、36.9711,均P<0.05)。结论:新疆叶城县维吾尔族6~12岁儿童近视患病率6.75%,而非近视远视储备不足检出率高达75.51%,预测近视高危儿童人数较多,故儿童的远视储备早期监测对于近视防控策略至关重要。 展开更多
关键词 新疆 维吾尔族 近视 远视储备 儿童
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Pea-like MoS_(2)@NiS_(1.03)-carbon heterostructured hollow nanofibers for high-performance sodium storage 被引量:4
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作者 Songwei Gao Yixiang He +10 位作者 Guichu Yue Huaike Li Shuai Li Jingchong Liu Beibei Miao Jie Bai Zhimin Cui Nu Wang Qianfan Zhang Lei Jiang yong zhao 《Carbon Energy》 SCIE CSCD 2023年第4期42-54,共13页
The rational synergy of chemical composition and spatial nanostructures of electrode materials play important roles in high-performance energy storage devices.Here,we designed pea-like MoS_(2)@NiS_(1.03)-carbon hollow... The rational synergy of chemical composition and spatial nanostructures of electrode materials play important roles in high-performance energy storage devices.Here,we designed pea-like MoS_(2)@NiS_(1.03)-carbon hollow nanofibers using a simple electrospinning and thermal treatment method.The hierarchical hollow nanofiber is composed of a nitrogen-doped carbon-coated NiS_(1.03) tube wall,in which pea-like uniformly discrete MoS_(2) nanoparticles are enclosed.As a sodium-ion battery electrode material,the MoS_(2)@NiS_(1.03)-carbon hollow nanofibers have abundant diphasic heterointerfaces,a conductive network,and appropriate volume variation-buffering spaces,which can facilitate ion diffusion kinetics,shorten the diffusion path of electrons/ion,and buffer volume expansion during Na^(+)insertion/extraction.It shows outstanding rate capacity and long-cycle performance in a sodium-ion battery.This heterogeneous hollow nanoarchitectures designing enlightens an efficacious strategy to boost the capacity and long-life stability of sodium storage performance of electrode materials. 展开更多
关键词 density functional theory electrospinning HETEROSTRUCTURE hollow nanofibers molybdenum disulfide sodium-ion batteries
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Integrated simulation and monitoring to analyze failure mechanism of the anti-dip layered slope with soft and hard rock interbedding 被引量:2
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作者 Jinduo Li Yuan Gao +5 位作者 Tianhong Yang Penghai Zhang yong zhao Wenxue Deng Honglei Liu Feiyue Liu 《International Journal of Mining Science and Technology》 SCIE EI CAS CSCD 2023年第9期1147-1164,共18页
The significant difference between the mechanical properties of soft rock and hard rock results in the complexity of the failure mode of the anti-dip layered slope with soft and hard rock interbedding.In order to reve... The significant difference between the mechanical properties of soft rock and hard rock results in the complexity of the failure mode of the anti-dip layered slope with soft and hard rock interbedding.In order to reveal the landslide mechanism,taking the north slope of Fushun West Open-pit Mine as an example,this paper analyzed the failure mechanism of different landslides with monitoring and field surveys,and simulated the evolution of landslides.The study indicated that when the green mudstone(hard rock)of the anti-dip slope contains siltized intercalations(soft rock),the existence of weak layers not only aggravates the toppling deformation of anti-dip layered slope with high dip,but also causes the shear failure of anti-dip layered slope with stable low dip.The shear failure including subsidence induced sliding and wedge failure mainly exists in the unloading zone of the slope.Its failure depth and failure time were far less than that of toppling failure.In terms of the development characteristics of deformation,toppling deformation has the long-term and progressive characteristics,but shear failure deformation has the abrupt and transient characteristics.This study has deepened the understanding of such slope landslide mechanism,and can provide reference for similar engineering. 展开更多
关键词 Anti-dip layered slope Soft and hard rock interbedding Toppling failure Wedge failure Fushun West Open-pit Mine
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Two-view attention-guided convolutional neural network for mammographic image classification 被引量:2
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作者 Lilei Sun Jie Wen +4 位作者 Junqian Wang yong zhao Bob Zhang Jian Wu yong Xu 《CAAI Transactions on Intelligence Technology》 SCIE EI 2023年第2期453-467,共15页
Deep learning has been widely used in the field of mammographic image classification owing to its superiority in automatic feature extraction.However,general deep learning models cannot achieve very satisfactory class... Deep learning has been widely used in the field of mammographic image classification owing to its superiority in automatic feature extraction.However,general deep learning models cannot achieve very satisfactory classification results on mammographic images because these models are not specifically designed for mammographic images and do not take the specific traits of these images into account.To exploit the essential discriminant information of mammographic images,we propose a novel classification method based on a convolutional neural network.Specifically,the proposed method designs two branches to extract the discriminative features from mammographic images from the mediolateral oblique and craniocaudal(CC)mammographic views.The features extracted from the two-view mammographic images contain complementary information that enables breast cancer to be more easily distinguished.Moreover,the attention block is introduced to capture the channel-wise information by adjusting the weight of each feature map,which is beneficial to emphasising the important features of mammographic images.Furthermore,we add a penalty term based on the fuzzy cluster algorithm to the cross-entropy function,which improves the generalisation ability of the classification model by maximising the interclass distance and minimising the intraclass distance of the samples.The experimental results on The Digital database for Screening Mammography INbreast and MIAS mammography databases illustrate that the proposed method achieves the best classification performance and is more robust than the compared state-ofthe-art classification methods. 展开更多
关键词 convolutional neural network deep learning medical image processing mammographic image
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Stress wave analysis of high-voltage pulse discharge rock fragmentation based on plasma channel impedance model 被引量:1
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作者 黄仕杰 刘毅 +5 位作者 赵勇 徐尤来 林福昌 李化 张钦 李柳霞 《Plasma Science and Technology》 SCIE EI CAS CSCD 2023年第6期52-64,共13页
High-voltage pulse discharge(HVPD)rock fragmentation controls a plasma channel forming inside the rock by adjusting the electrical parameters,electrode type,etc.In this work,an HVPD rock fragmentation test platform wa... High-voltage pulse discharge(HVPD)rock fragmentation controls a plasma channel forming inside the rock by adjusting the electrical parameters,electrode type,etc.In this work,an HVPD rock fragmentation test platform was built and the test waveforms were measured.Considering the effects of temperature,channel expansion and electromagnetic radiation,the impedance model of the plasma channel in the rock was established.The parameters and initial values of the model were determined by an iterative computational process.The model calculation results can reasonably characterize the development of the plasma channel in the rock and estimate the shock wave characteristics.Based on the plasma channel impedance model,the temporal and spatial distribution characteristics of the radial stress and tangential stress in the rock were calculated,and the rock fragmentation effect of the HVPD was analyzed. 展开更多
关键词 stress wave shock wave plasma channel impedance model rock fragmentation high-voltage pulse discharge
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The worldwide allometric relationship in anatomical structures for plant roots 被引量:1
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作者 Yue Zhang Jing-Jing Cao +3 位作者 Qing-Pei Yang Ming-Zuo Wu yong zhao De-Liang Kong 《Plant Diversity》 SCIE CAS CSCD 2023年第6期621-629,共9页
The cortex(i.e.,absorptive tissue)and stele(transportive vascular tissue)are fundamental to the function of plant roots.Unraveling how these anatomical structures are assembled in absorptive roots is essential for our... The cortex(i.e.,absorptive tissue)and stele(transportive vascular tissue)are fundamental to the function of plant roots.Unraveling how these anatomical structures are assembled in absorptive roots is essential for our understanding of plant ecology,physiology,and plant responses to global environmental changes.In this review,we first compile a large data set on anatomical traits in absorptive roots,including cortex thickness and stele radius,across 698 observations and 512 species.Using this data set,we reveal a common root allometry in absorptive root structures,i.e.,cortex thickness increases much faster than stele radius with increasing root diameter(hereafter,root allometry).Root allometry is further validated within and across plant growth forms(woody,grass,and liana species),mycorrhiza types(arbuscular mycorrhiza,ectomycorrhiza,and orchid mycorrhizas),phylogenetic gradients(from ferns to Orchidaceae),and environmental change scenarios(e.g.,elevation of atmospheric CO_(2)concentration and nitrogen fertilization).These findings indicate that root allometry is common in plants.Importantly,root allometry varies greatly across species.We then summarize recent research on the mechanisms of root allometry and potential issues regarding these mechanisms.We further discuss ecological and evolutionary implications of root allometry.Finally,we propose several important research directions that should be pursued regarding root allometry. 展开更多
关键词 Allometric relationship Root dimeter Cortex thickness Stele radius
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低位直肠癌术后前切除综合征的诊治进展 被引量:1
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作者 刘非凡 卓光鑽 +3 位作者 赵玉涓 张斌 赵勇 丁健华 《世界华人消化杂志》 CAS 2023年第5期178-183,共6页
直肠癌是临床上常见的消化道恶性肿瘤之一,低位直肠癌术后高达90%的患者会出现不同程度的排便频率增加、大便失禁或排泄功能障碍等临床表现,这种广泛的症状被称为低位前切除综合征(low anterior resection syndrome,LARS),这种肠功能紊... 直肠癌是临床上常见的消化道恶性肿瘤之一,低位直肠癌术后高达90%的患者会出现不同程度的排便频率增加、大便失禁或排泄功能障碍等临床表现,这种广泛的症状被称为低位前切除综合征(low anterior resection syndrome,LARS),这种肠功能紊乱对生活质量有显著的负面影响.本文就国内外有关LARS的发病机制、危险因素、评估方法及治疗策略进展进行综述. 展开更多
关键词 低位直肠癌 低位前切除综合征 评估方法 诊治
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相平衡的教学设计案例与思考 被引量:1
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作者 王女 赵勇 刘兆阅 《大学化学》 CAS 2023年第10期129-136,共8页
“相平衡”是物理化学的重要部分,本文以“纯物质系统相图分析”为例,介绍了围绕“问题探究式”教学模式开展教学内容、教学目标、教学设计的基本理念与思路,致力于培养学生发现问题、分析问题、解决问题的能力,取得了很好的教学效果。
关键词 物理化学 相平衡 相图 教学设计
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Permeability evolution mechanism and the optimum permeability determination of uranium leaching from low-permeability sandstone treated with low-frequency vibration
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作者 yong zhao Xiqi Li +2 位作者 Lin Lei Ling Chen Zhiping Luo 《Journal of Rock Mechanics and Geotechnical Engineering》 SCIE CSCD 2023年第10期2597-2610,共14页
Low-frequency vibrations can effectively improve natural sandstone permeability,and higher vibration frequency is associated with larger permeability.However,the optimum permeability and permeability evolution mechani... Low-frequency vibrations can effectively improve natural sandstone permeability,and higher vibration frequency is associated with larger permeability.However,the optimum permeability and permeability evolution mechanism for uranium leaching and the relationship between permeability and the change of chemical reactive rate affecting uranium leaching have not been determined.To solve the above problems,in this study,identical homogeneous sandstone samples were selected to simulate lowpermeability sandstone;a permeability evolution model considering the combined action of vibration stress,pore water pressure,water flow impact force,and chemical erosion was established;and vibration leaching experiments were performed to test the model accuracy.Both the permeability and chemical reactions were found to simultaneously restrict U6þleaching,and the vibration treatment increased the permeability,causing the U6þleaching reaction to no longer be diffusion-constrained but to be primarily controlled by the reaction rate.Changes of the model calculation parameters were further analyzed to determine the permeability evolution mechanism under the influence of vibration and chemical erosion,to prove the correctness of the mechanism according to the experimental results,and to develop a new method for determining the optimum permeability in uranium leaching.The uranium leaching was found to primarily follow a process consisting of(1)a permeability control stage,(2)achieving the optimum permeability,(3)a chemical reactive rate control stage,and(4)a channel flow stage.The resolution of these problems is of great significance for facilitating the application and promotion of lowfrequency vibration in the CO_(2)+O_(2) leaching process. 展开更多
关键词 Low-frequency vibration Low-permeability sandstone Uranium migration Permeability evolution mechanism Chemical reactive rate Optimum permeability
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A Spacecra Equipment Layout Optimization Method for Diverse and Competitive Design
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作者 Wei Cong yong zhao +2 位作者 Bingxiao Du Senlin Huo Xianqi Chen 《Computer Modeling in Engineering & Sciences》 SCIE EI 2023年第7期621-654,共34页
The spacecraequipment layout optimization design(SELOD)problems with complicated performance con-straints and diversity are studied in this paper.The previous literature uses the gradient-based algorithm to obtain op... The spacecraequipment layout optimization design(SELOD)problems with complicated performance con-straints and diversity are studied in this paper.The previous literature uses the gradient-based algorithm to obtain optimized non-overlap layout schemes from randomly initialized cases eectively.However,these local optimal solutions are too dicult to jump out of their current relative geometry relationships,signi􀀀cantly limiting their further improvement in performance indicators.Therefore,considering the geometric diversity of layout schemes is put forward to alleviate this limitation.First,similarity measures,including modi􀀀ed cosine similarity and gaussian kernel function similarity,are introduced into the layout optimization process.Then the optimization produces a set of feasible layout candidates with the most remarkable dierence in geometric distribution and the most representative schemes are sampled.Finally,these feasible geometric solutions are used as initial solutions to optimize the physical performance indicators of the spacecra,and diversi􀀀ed layout schemes of spacecraequipment are generated for the engineering practice.The validity and eectiveness of the proposed methodology are demonstrated by two SELOD applications. 展开更多
关键词 Layout optimization non-overlap similarity measures sampling methods physical performance
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Study of beam divergence and thrust vector eccentricity characteristics of the Hall thruster based on dual Faraday probe array planes and its applications
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作者 陈新伟 赵勇 +11 位作者 田恺 高俊 孙明明 孙新锋 郭宁 张宏 王尚民 冯杰 陈焘 耿海 杨俊泰 史楷 《Plasma Science and Technology》 SCIE EI CAS CSCD 2023年第5期104-115,共12页
The accurate knowledge of the thrust vector eccentricity and beam divergence characteristics of Hall thrusters are of significant engineering value for the beneficial integration and successful application of Hall thr... The accurate knowledge of the thrust vector eccentricity and beam divergence characteristics of Hall thrusters are of significant engineering value for the beneficial integration and successful application of Hall thrusters on spacecraft.For the characteristics of the plume bipolar diffusion due to the annular discharge channel of the Hall thruster,a Gaussian-fitted method for thrust vector deviation angle and beam divergence of Hall thrusters based on dual Faraday probe array planes was proposed in respect of the Hall thruster beam characteristics.The results show that the ratios of the deviation between the maximum and minimum values of the beam divergence angle and the thrust vector eccentricity angle using a Gaussian fit to the optimized Faraday probe dual plane to the mean value are 1.4%and 11.5%,respectively.The optimized thrust vector eccentricity angle obtained has been substantially improved,by approximately 20%.The beam divergence angle calculated using a Gaussian fitting to the optimized Faraday probe dual plane is approximately identical to the non-optimized one.The beam divergence and thrust vector eccentricity angles for different anode mass flow rates were obtained by averaging the beam divergence and thrust vector eccentricity angles calculated by the dual-plane,Gaussian-fitted ion current density method for different cross-sections.The study not only allows for an immediate and effective tool for determining the design of thrust vector adjustment mechanisms of spacecraft with different power Hall thrusters but also for characterizing the 3D spatial distribution of the Hall thruster plume. 展开更多
关键词 Hall thruster beam divergence thrust vector eccentricity dual Faraday probe array planes
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Silencing of the Nonspecific Phospholipase C6(NPC6)Gene Induces Ricinoleic Acid Accumulation in Castor Seeds
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作者 yong zhao Lili Li +7 位作者 Rui Luo Mu Peng Tongtong Jiang Mingda Yin Yanpeng Wen Zihan Wang Fenglan Huang Fanjuan Meng 《Phyton-International Journal of Experimental Botany》 SCIE 2023年第12期3237-3250,共14页
Castor,scientifically known as Ricinus communis L.,is among the top ten oil crops globally.It is considered a renewable resource and is commonly referred to as‘green oil’.Castor seeds contain castor oil as their mai... Castor,scientifically known as Ricinus communis L.,is among the top ten oil crops globally.It is considered a renewable resource and is commonly referred to as‘green oil’.Castor seeds contain castor oil as their main component,which is predominantly composed of ricinoleic acid.This study utilized RNAi technology to silence the NPC6 gene in NO.2129 castor,resulting in the creation of mutant plants L1 and L2.The weight of 100 dry seed kernels from L1 and L2 exceeds that from NO.2129.The crude fat and ricinoleic acid levels of L1 and L2 were higher than those of NO.2129 at various developmental stages.In the proteomics analysis of 60-day-old castor seeds,a total of 21 differentially expressed proteins were identified,out of which 19 were successfully recognized.Eleven of the differentially expressed proteins identified were legumins,which play a crucial role in nutrient storage within the seed.Silencing the NPC6 gene results in the accumulation of ricinoleic acid in castor seeds.The findings of this study not only enhance our knowledge of NPC6’s role in regulating castor seed oil synthesis but also offer fresh perspectives for investigating oil synthesis and accumulation in other plant species. 展开更多
关键词 Ricinus communis L ricinoleic acid NPC6 RNAI
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Proteomic Analyses of Three Inflorescence Styles of Castor(Ricinus communis L.)at Different Developmental Stages
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作者 Xue Lei yong zhao +5 位作者 Rui Luo Mingda Yin Yanpeng Wen Zhiyan Wang Xuemei Hu Fenglan Huang 《Phyton-International Journal of Experimental Botany》 SCIE 2023年第5期1621-1632,共12页
Castor(Ricinus communis L.)is one of ten oil crops in the world and has complex inflorescence styles.Generally,castor has three inflorescence types:single female inflorescence(SiFF),standard female inflorescence(StFF)... Castor(Ricinus communis L.)is one of ten oil crops in the world and has complex inflorescence styles.Generally,castor has three inflorescence types:single female inflorescence(SiFF),standard female inflorescence(StFF)and bisexual inflorescence(BF).StFF is realized as a restorer line and as a maintainer line,which was applied to castor hybrid breeding.However,the developmental mechanism of the three inflorescences is not clear.Therefore,we used proteomic techniques to analyze different inflorescence styles.A total of 72 diferentially abundant protein species(DAPs)were detected.These DAPs are primarily involved in carbon and energy metabolism and carbon fixation in the photosynthetic organism pathway.The results showed that DAPs are involved in photosynthesis to control the distribution of imported carbohydrates and exported photoassimilates and thus affect the inflorescence development of castor.In addition,these DAPs are also involved in cysteine and methionine metabolism.Quantitative real-time PCR(qRT-PCR)results demonstrated that the proteomics data collected in this study were reliable.Our findings indicate that the carbon cycle and amino acid metabolism influence the inflorescence development of castor. 展开更多
关键词 Ricinus communis L INFLORESCENCE PROTEOMICS
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