A study on the relationship between changes in serum hs-CRP levels and Chinese ischemic stroke subclassification

Objective: To study the relationship between changes in serum high sensitivity C-reactive protein (hs-CRP) levels and Chinese ischemic stroke subclassification (CISS), and explore the action mechanism of hs-CRP in the pathogenetic process of ischemic stroke. Methods: The serum hs-CRP level was measured in all subjects (including the healthy). As to 177 ischemic stroke patients, they were subclassified based on causes and pathogenesis to explore the relationship between the serum hs-CRP level and CISS. Results: The serum hs-CRP level in the ischemic stroke group was significantly higher than that in the control group (p < .05). The difference of the serum hs-CRP levels in different Chinese ischemic stroke subtypes was of statistical significance (p < .05). Conclusions: The level of serum hs-CRP is closely associated with the incidence of the ischemic stroke, and the difference of the serum hs-CRP levels in different Chinese ischemic stroke subtypes is of statistical significance.

Influence of Different Equations of State on Simulation Results of Supercritical CO_(2) Centrifugal Compressor

Supercritical CO_(2)(SCO_(2))Brayton cycle has received more and more attention in the field of power generation due to its high cycle efficiency and compact structure.SCO_(2) compressor is the core component of the cycle,and the improvement of its performance is the key to improving the efficiency of the entire cycle.However,the operation of the SCO_(2) compressor near the critical point has brought many design and operation problems.Based on the Reynolds Averaged Navier-Stokes(RANS)model,the performance and flow field of SCO_(2) centrifugal compressors based on different CO_(2) working fluid models are numerically investigated in this paper.The stability and convergence of the compressor steady-state simulation are also discussed.The results show that the fluid based on the Span-Wanger(SW)equation can obtain a more ideal compressor performance curve and capture a more accurate flow field structure,while the CO_(2) ideal gas is not suitable for the calculation of SCO_(2) centrifugal compressors.But its flow field can be used as the initial flow field for numerical calculation of centrifugal compressor based on CO_(2) real gas.

Dolomitization by Penesaline Sea Water in Early Cambrian Longwangmiao Formation, Central Sichuan Basin, China

The Lower Cambrian Longwangmiao Formation shoal dolostone reservoir in Sichuan Basin is currently an exploration and research highlight in China. Reservoir rocks mainly consist of crystalline dolomite with residual grain texture, and dolarenite of which the arene is mainly composed of muddy to micritic dolomite with some crystalline grain directionally aligned. The trace element indicates that the dolomites of Longwangmiao Formation may be related to the high salinity of sea water. The oxygen isotope values of crystalline dolomite and dolarenite are both similar to that of the Early Cambrian marine dolomites, and the carbon isotope values of every kind of dolomites are completely overlapped with that of the seawater in Early Cambrian, indicating the dolomitization fluid is originated from the Early Cambrian sea water. The restricted marine biological communities and a small amount of gypsum pseudonodule seen in muddy to micritic dolomite indicate that the sea water in Early Cambrian was restricted and evaporated. However, the general lack of massive evaporite mineral and gypsum karst breccia indicates that the salinity of sea water during dolomitization was lower than the value of gypsum＇s precipitation. The Longwangmiao Formation consists of several high-frequency sedimentary cycles, indicating frequent sea level changes. This study indicates that massive dolomitization may also occur in underwater palaeohigh in carbonate platform through the reflux of penesaline sea water driven by a combination of high-and low-frequency sea-level changes. This kind of dolomitization can explain the generation of massive dolomites in the absence of evaporite precipitation, and further indicates that replacement dolomites can be produced by sea water with a wide range of salinity（normal, penesaline to hypersaline）.

Gas accumulation conditions and key technologies for exploration & development of Sinian and Cambrian gas reservoirs in Anyue gasfield

Exploration of the Sinian-Lower Paleozoic formations in the Sichuan Basin starts from the 1950s,and is tortuous and complex.To summarize the exploration experiences is of great significance of reference for exploration of oil and gas in deep carbonate rocks of the Sichuan Basin.Gas accumulation in the Anyue oversize gasfield is chiefly controlled by the Deyang-Anyue intra-platform rift and central Sichuan paleouplift.The intra-platform rift controls the scale hydrocarbon generation center and effective hydrocarbon plays.The Anyue gasfield is characterized by near-source hydrocarbon accumulation.The marginal zone of intra-platform rift and high part of the paleouplift control the scale distribution of favorable facies belts of reservoir development,and overlapped by paleokarstic reformation,the reservoirs are widely distributed.The intra-platform rift and paleouplift jointly control formation of the scale traps and hydrocarbon enrichment.Gas reservoir features and major controlling factors for hydrocarbon accumulation have some differences in the main play strata,such as Longwangmiao Formation,and Member 4 and Member 2 of Dengying Formation.The gas reservoir in the Longwangmiao Formation is a lithologic gas reservoir under the tectonic setting,and the inherited paleouplift is a key for reservoir formation and hydrocarbon accumulation.The gas reservoir in the Member 4 of Dengying Formation is mainly controlled by large structural-stratigraphic composite traps,and the gas reservoir in the Member 2 of Dengying Formation is the structural trap.Distribution of the large gasfields in the Dengying Formation is controlled by the intra-platform rift,near-source hydrocarbon-reservoir configuration controlled by the ancient erosion plane and stratigraphic sealing in the updip direction.For exploration and development of the Anyue gasfield,four series of technologies are developed,namely,reservoir seismic fine description technology,well logging fine evaluation technology of gas layers,fast drilling technology of complex strata,and stimulation technology for high temperature and high pressure gas layers.Technical progresses provide powerful guarantee for efficient exploration and development of the oversize gasfields.

Physiological response of the razor clam Sinonovacula constricta exposed to hyposalinity stress

The razor clam Sinonovacula constricta is an economically important bivalve species in China,which inhabits the mudflat of intertidal and estuaries areas and frequently suffers the low salinity stress due to heavy rain events.The present study investigated the effects of hyposalinity stress(salinity 10,5,3,and 1)on osmoregulation and haemolymph microbiota in S.constricta after 7 days of exposure.The results showed that the survival rate of razor clams was only significantly reduced in the 1 ppt group compared to the control group(salinity 20)(P<0.05).Haemolymph osmolality in razor clams reduced significantly with decreasing salinities(P<0.05).Taurine,arginine,alanine and ornithine were the dominant free amino acids(FAAs)with higher contents in the haemolymph.Exposure to low salinities altered the composition of haemolymph FAAs,with alanine being the highest in the control group and taurine being the highest in the low salinity(LS)groups.Hyposalinity stress caused an increase in Na+/K+-ATPase(NKA)activity in gills,and histological analysis revealed severe hyperplasia in gills and a significant reduction in the length of gill filaments(P<0.05).The microbial community variation in the haemolymph assessed by 16S rRNA sequencing explains that bacterial communities was shifted under low salinity stress.At the genus level,the relative abundance of Marinobacterium,Marinomonas and Pseudomonas changed significantly under hyposalinity stress(P<0.05).These findings give further insight into the physiological responses and potential adaptation strategies of razor clams to hyposalinity stress and provide information for the development of inland low salinity culture.