Unconventional fermions in the immensely studied topological semimetals are the source for rich exotic topological properties.Here,using symmetry analysis and first-principles calculations,we propose the coexistence o...Unconventional fermions in the immensely studied topological semimetals are the source for rich exotic topological properties.Here,using symmetry analysis and first-principles calculations,we propose the coexistence of multiple topological nodal structure in LaSb_(2),including topological nodal surfaces,nodal lines and in particular eightfold degenerate nodal points,which have been scarcely observed in a single material.Further,utilizing angle-resolved photoemission spectroscopy,we confirm the existence of nodal surfaces and eightfold degenerate nodal points in LaSb_(2).The intriguing multiple topological nodal structure might play a crucial role in giving rise to the large linear magnetoresistance.Our work renews the insights into the exotic topological phenomena in LaSb_(2).展开更多
Background:Delayed graft function(DGF)is the main cause of renal function failure after kidney transplantation.This study aims at investigating the value of hypothermic machine perfusion(HMP)parameters combined with p...Background:Delayed graft function(DGF)is the main cause of renal function failure after kidney transplantation.This study aims at investigating the value of hypothermic machine perfusion(HMP)parameters combined with perfusate biomarkers on predicting DGF and the time of renal function recovery after deceased donor(DD)kidney transplantation.Methods:HMP parameters,perfusate biomarkers and baseline characteristics of 113 DD kidney transplantations from January 1,2019 to August 31,2019 in the First Affiliated Hospital of Xi’an Jiaotong University were retrospectively analyzed using univariate and multivariate logistic regression analysis.Results:In this study,the DGF incidence was 17.7%(20/113);The multivariate logistic regression results showed that terminal resistance(OR:1.879,95%CI 1.145-3.56)and glutathione S-transferase(GST)(OR=1.62,95%CI 1.23-2.46)were risk factors for DGF;The Cox model analysis indicated that terminal resistance was an independent hazard factor for renal function recovery time(HR=0.823,95%CI 0.735-0.981).The model combining terminal resistance and GST(AUC=0.888,95%CI:0.842-0.933)significantly improved the DGF predictability compared with the use of terminal resistance(AUC=0.756,95%CI 0.693-0.818)or GST alone(AUC=0.729,95%CI 0.591-0.806).Conclusion:According to the factors analyzed in this study,the combination of HMP parameters and perfusate biomarkers displays a potent DGF predictive value.展开更多
基金supported by the National Key R&D Program of China(Grant No.2023YFA1406304)the National Natural Science Foundation of China(Grant Nos.U2032208,12222413,11874264,12074181,11834006,and 12104217)+9 种基金the Natural Science Foundation of Shanghai(Grant Nos.23ZR1482200,22ZR1473300,and 14ZR1447600)the Shanghai Science and Technology Innovation Action Plan(Grant No.21JC1402000)the Open Projects from State Key Laboratory of Functional Materials for Informatics(Grant No.SKL2022)the Double First-Class Initiative Fund of Shanghai Tech Universitythe fund of Science and Technology on Surface Physics and Chemistry Laboratory(Grant No.6142A02200102)supported by ME2Project(Grant No.11227902)from the National Natural Science Foundation of Chinasupported by the National Key Projects for Research and Development of China(Grant No.2021YFA1400400)the Fundamental Research Funds for the Central Universities(Grant No.020414380185)the Natural Science Foundation of Jiangsu Province(Grant No.BK20200007)the Fok Ying-Tong Education Foundation of China(Grant No.161006)。
文摘Unconventional fermions in the immensely studied topological semimetals are the source for rich exotic topological properties.Here,using symmetry analysis and first-principles calculations,we propose the coexistence of multiple topological nodal structure in LaSb_(2),including topological nodal surfaces,nodal lines and in particular eightfold degenerate nodal points,which have been scarcely observed in a single material.Further,utilizing angle-resolved photoemission spectroscopy,we confirm the existence of nodal surfaces and eightfold degenerate nodal points in LaSb_(2).The intriguing multiple topological nodal structure might play a crucial role in giving rise to the large linear magnetoresistance.Our work renews the insights into the exotic topological phenomena in LaSb_(2).
基金This work was supported by the grants from the National Natural Science Foundation of China(Nos.81670681,81760137,81870514,81970668 and 81970670)the Fundamental Research Funds for the Central Universities(No.xjj2018091)+1 种基金the Clinical Research Award of the First Affiliated Hospital of Xi’an Jiaotong University(No.XJTU1AF-CRF-2019-008)the Special Supportive Program for Organ Transplantation by COTDF(No.2019JYJH04).
文摘Background:Delayed graft function(DGF)is the main cause of renal function failure after kidney transplantation.This study aims at investigating the value of hypothermic machine perfusion(HMP)parameters combined with perfusate biomarkers on predicting DGF and the time of renal function recovery after deceased donor(DD)kidney transplantation.Methods:HMP parameters,perfusate biomarkers and baseline characteristics of 113 DD kidney transplantations from January 1,2019 to August 31,2019 in the First Affiliated Hospital of Xi’an Jiaotong University were retrospectively analyzed using univariate and multivariate logistic regression analysis.Results:In this study,the DGF incidence was 17.7%(20/113);The multivariate logistic regression results showed that terminal resistance(OR:1.879,95%CI 1.145-3.56)and glutathione S-transferase(GST)(OR=1.62,95%CI 1.23-2.46)were risk factors for DGF;The Cox model analysis indicated that terminal resistance was an independent hazard factor for renal function recovery time(HR=0.823,95%CI 0.735-0.981).The model combining terminal resistance and GST(AUC=0.888,95%CI:0.842-0.933)significantly improved the DGF predictability compared with the use of terminal resistance(AUC=0.756,95%CI 0.693-0.818)or GST alone(AUC=0.729,95%CI 0.591-0.806).Conclusion:According to the factors analyzed in this study,the combination of HMP parameters and perfusate biomarkers displays a potent DGF predictive value.
