Thermally Conductive and UV-EMI Shielding Electronic Textiles for Unrestricted and Multifaceted Health Monitoring

Skin-attachable electronics have garnered considerable research attention in health monitoring and artificial intelligence domains,whereas susceptibility to elec-tromagnetic interference(EMI),heat accumulation issues,and ultraviolet(UV)-induced aging problems pose significant constraints on their potential applications.Here,an ultra-elas-tic,highly breathable,and thermal-comfortable epidermal sensor with exceptional UV-EMI shielding performance and remarkable thermal conductivity is developed for high-fidelity monitoring of multiple human electrophysiological signals.Via filling the elastomeric microfibers with thermally conductive boron nitride nanoparticles and bridging the insulating fiber interfaces by plating Ag nanoparticles(NPs),an interwoven thermal con-ducting fiber network(0.72 W m^(-1) K^(-1))is constructed benefiting from the seamless thermal interfaces,facilitating unimpeded heat dissipation for comfort skin wearing.More excitingly,the elastomeric fiber substrates simultaneously achieve outstanding UV protection(UPF=143.1)and EMI shielding(SET>65,X-band)capabilities owing to the high electrical conductivity and surface plasmon resonance of Ag NPs.Furthermore,an electronic textile prepared by printing liquid metal on the UV-EMI shielding and thermally conductive nonwoven textile is finally utilized as an advanced epidermal sensor,which succeeds in monitoring different electrophysiological signals under vigorous electromagnetic interference.This research paves the way for developing protective and environmentally adaptive epidermal electronics for next-generation health regulation.

Comprehensive analyses of the proteome and ubiquitome revealed mechanism of high temperature accelerating petal abscission in tree peony

Tree peony(Paeonia suffruticosa Andrews)is a well-known ornamental plant with high economic value,but the short fluorescence is a key obstacle to its ornamental value and industry development.High temperature accelerates flower senescence and abscission,but the associated mechanisms are poorly understood.In this study,the tandem mass tag(TMT)proteome and label-free quantitative ubiquitome from tree peony cut flowers treated with 20℃for 0 h(RT0),20℃or 28℃for 60 h(RT60 or HT60)were examined based on morphological observation,respectively.Totally,6970 proteins and 1545 lysine ubiquitinated(Kub)sites in 844 proteins were identified.Hydrophilic residues(such as glutamate and aspartate)neighboring the Kub sites were in preference,and 36.01%of the Kub sites were located on the protein surface.The differentially expressed proteins(DEPs)and Kub-DEPs in HT60 vs RT60 were mainly enriched in ribosomal protein,protein biosynthesis,secondary metabolites biosynthesis,flavonoid metabolism,carbohydrate catabolism,and auxin biosynthesis and signaling revealed by GO and KEGG analysis,accompanying the increase of endogenous abscisic acid(ABA)accumulation and decrease of endogenous indoleacetic acid(IAA)level.Additionally,the expression patterns of six enzymes(SAMS,ACO,YUC,CHS,ANS and PFK)putatively with Kub modifications were analyzed by proteome and real-time quantitative RT-PCR.The cell-free degradation assays showed PsSAMS and PsACO proteins could be degraded via the 26 S proteasome system in tree peony flowers.Finally,a working model was proposed for the acceleration of flower senescence and abscission by high temperature.In summary,all results contributed to understanding the mechanism of flower senescence induced by high temperature and prolonging fluorescence in tree peony.

“Half of the Node Records Are Forged?”: The Problemof Node Records Forgery in Ethereum Network

Ethereum, currently the most widely utilized smart contracts platform, anchors the security of myriad smartcontracts upon its own robustness. Its foundational peer-to-peer network facilitates a dependable node connectionmechanism, whereas an efficient data-sharing protocol constitutes as the bedrock of Blockchain network security.In this paper, we propose NodeHunter, an Ethereum network detector implemented through the application ofsimulation technology, which is capable of aggregating all node records within the network and the interconnectednessbetween them. Utilizing this connection information, NodeHunter can procure more comprehensive insightsfor network status analysis compared to preceding detection methodologies. Throughout a three-month period ofunbroken surveillance of the Ethereum network, we obtained an excess of two million node records along with overone hundred million node acquaintances. Analysis of the gathered data revealed that an alarming 49% or more ofthese node records were maliciously forged.

凉血解毒消斑汤治疗寻常型银屑病临床对照研究

本研究的目的是探究凉血解毒消斑汤治疗寻常型银屑病的临床应用效果。随机选取杭州医学院附属医院2023年6月-2023年12月来本院就诊的50例寻常型银屑病患者为研究对象,使用凉血解毒消斑汤治疗为观察组,对照组则采用传统治疗方法。结果显示,在治疗后的3个月内,观察组患者的病情得到了显著改善,平均病情评分由初始的6.8降至2.3,且无明显不良反应发生。而对照组患者的病情改善较慢,平均病情评分由初始的6.8降至4.5。统计学分析显示,观察组的治疗效果显著优于对照组(P<0.05)。此外,观察组患者的生活质量也有明显提高,皮肤瘙痒、脱屑等症状明显减轻,对疾病的认知和接受程度也有所增加。在随访期间,观察组患者的复发率较低,仅有10%的患者出现了病情反复,而对照组患者的复发率达到了30%。由此可见,凉血解毒消斑汤对于寻常型银屑病的治疗具有显著的临床应用效果,不仅可以改善患者的症状,提高生活质量,还能有效降低疾病的复发率,值得在临床中推广应用。

Superelastic Radiative Cooling Metafabric for Comfortable Epidermal Electrophysiological Monitoring

Epidermal electronics with superb passive-cooling capabilities are of great value for both daytime outdoor dressing comfort and low-carbon economy. Herein, a multifunctional and skinattachable electronic is rationally developed on a porous all-elastomer metafabric for efficient passive daytime radiative cooling(PDRC) and human electrophysiological monitoring. The cooling characteristics are realized through the homogeneous impregnation of polytetrafluoroethylene microparticles in the styrene–ethylene–butylene–styrene fibers, and the rational regulation of microporosity in SEBS/PTFE metafabrics, thus synergistically backscatter ultraviolet–visible–near-infrared light(maximum reflectance over 98.0%) to minimize heat absorption while efficiently emit human-body midinfrared radiation to the sky. As a result, the developed PDRC metafabric achieves approximately 17℃ cooling effects in an outdoor daytime environment and completely retains its passive cooling performance even under 50% stretching. Further, high-fidelity electrophysiological monitoring capability is also implemented in the breathable and skin-conformal metafabric through liquid metal printing, enabling the accurate acquisition of human electrocardiograph, surface electromyogram, and electroencephalograph signals for comfortable and lengthy health regulation. Hence, the fabricated superelastic PDRC metafabric opens a new avenue for the development of body-comfortable electronics and low-carbon wearing technologies.

Dual functions of PsmiR172b-PsTOE3 module in dormancy release and flowering in tree peony (Paeonia suffruticosa)

MicroRNAs(miRNAs)are non-coding RNAs that interact with target genes and are involved in many physiological processes in plants.miR172-AP2 mainly plays a role in the regulation of f lowering time and floral organ differentiation.Bud dormancy release is necessary for forcing culture of tree peony in winter,but the mechanism of dormancy regulation is unclear.In this study,we found that a miR172 family member,PsmiR172b,was downregulated during chilling-induced bud dormancy release in tree peony,exhibiting a trend opposite to that of PsTOE3.RNA ligase-mediated(RLM)5-RACE(rapid amplification of cDNA ends)confirmed that miR172b targeted PsTOE3,and the cleavage site was between bases 12(T)and 13(C)within the complementary site to miR172b.The functions of miR172b and PsTOE3 were detected by virus-induced gene silencing(VIGS)and their overexpression in tree peony buds.PsmiR172b negatively regulated bud dormancy release,but PsTOE3 promoted bud dormancy release,and the genes associated with bud dormancy release,including PsEBB1,PsEBB3,PsCYCD,and PsBG6,were upregulated.Further analysis indicated that PsTOE3 directly regulated PsEBB1 by binding to its promoter,and the specific binding site was a C-repeat(ACCGAC).Ectopic expression in Arabidopsis revealed that the PsmiR172b-PsTOE3 module displayed conservative function in regulating f lowering.In conclusion,our results provided a novel insight into the functions of PsmiR172-PsTOE3 and possible molecular mechanism underlying bud dormancy release in tree peony.

Optimization of the Plugging Agent Dosage for High Temperature Salt Profile Control in Heavy Oil Reservoirs

After steam discharge in heavy oil reservoirs,the distribution of temperature,pressure,and permeability in different wells becomes irregular.Flow channels can easily be produced,which affect the sweep efficiency of the oil displacement.Previous studies have shown that the salting-out plugging method can effectively block these channels in high-temperature reservoirs,improve the suction profile,and increase oil production.In the present study,the optimal dosage of the plugging agent is determined taking into account connection transmissibility and inter-well volumes.Together with the connectivity model,a water flooding simulation model is introduced.Moreover,a non-gradient stochastic disturbance algorithm is used to obtain the optimal plugging agent dosage,which provides the basis for the high-temperature salting-out plugging agent adjustment in the field.

PsRGL1 negatively regulates chilling- and gibberellin-induced dormancy release by PsF-box1-mediated targeting for proteolytic degradation in tree peony

Tree peony bud endodormancy is a common survival strategy similar to many perennial woody plants in winter,and the activation of the GA signaling pathway is the key to breaking endodormancy.GA signal transduction is involved in many physiological processes.Although the GA-GID1-DELLA regulatory module is conserved in many plants,it has a set of specific components that add complexity to the GA response mechanism.DELLA proteins are key switches in GA signaling.Therefore,there is an urgent need to identify the key DELLA proteins involved in tree peony bud dormancy release.In this study,the prolonged chilling increased the content of endogenously active gibberellins.PsRGL1 among three DELLA proteins was significantly downregulated during chilling-and exogenous GA3-induced bud dormancy release by cell-free degradation assay,and a high level of polyubiquitination was detected.Silencing PsRGL1 accelerated bud dormancy release by increasing the expression of the genes associated with dormancy release,including PsCYCD,PsEBB1,PsEBB3,PsBG6,and PsBG9.Three F-box protein family members responded to chilling and GA3 treatments,resulting in PsF-box1 induction.Yeast two-hybrid and BiFC assays indicated that only PsF-box1 could bind to PsRGL1,and the binding site was in the C-terminal domain.PsF-box1 overexpression promoted dormancy release and upregulated the expression of the dormancy-related genes.In addition,yeast two-hybrid and pull-down assays showed that PsF-box1 also interacted with PsSKP1 to form an E3 ubiquitin ligase.These findings enriched the molecular mechanism of the GA signaling pathway during dormancy release,and enhanced the understanding of tree peony bud endodormancy.

Enhancing solar-driven overall water splitting via both sacrifice and noble metal free photocatalysis: copper cluster/boron-doped carbon nitride catalysts

The major impediment to the additional industrialization of water splitting is the high cost of the co-catalyst made of noble metals and the sacrificial reagent. A binary photocatalytic system, consisting of B-doped g-C_(3)N_(4) nanosheets(Cu_(20)@BCN-X) and atomically accurate copper clusters, is designed in this study. The copper clusters serve as co-catalysts for H_(2) evolution and exhibit Pt-like activity, whereas the nanosheets serve as carriers and semiconductor components for O_(2) evolution. Such binary system, created using simple techniques, demonstrates hydrogen bonding interactions that promote synergistic effects and efficient binding and charge transfer across the interface between the two components. Band position manipulation of carbon nitride nanosheets demonstrates a Z-scheme charge transfer mechanism between the nanosheets and copper clusters. This photocatalytic system can accomplish the photocatalytic overall water splitting process(259.9 μmol g^(-1)h^(-1)of H_(2) and 129.4 μmol g^(-1)h^(-1)of O_(2)) without using sacrificial agents or noble metal co-catalysts. This work lays the foundation for the design of overall water splitting catalysts by precisely manipulating the energy levels, and it also paves the way for commercialized photocatalytic catalysts that do not require noble metals or sacrificial chemicals.

Noncationic polymer-assisted carrier for nucleic acid drug delivery

Nucleic acid drugs are emerging as a novel biotherapeutic modality for disease treatment,targeting nucleic acids to regulate the protein translation process and thereby facilitating disease management.They hold significant promise in biomedical applications and treatment avenues.Given their negative charge,high molecular weight,and hydrophilic properties,nucleic acid drugs require carriers to traverse multiple biological barriers and facilitate intracellular delivery.Cationic material-based carriers present an unprecedented opportunity to address these challenges through electrostatic interactions with nucleic acids.However,concerns regarding the biosafety and cytotoxic responses of cationic materials have emerged in early clinical studies.As a result,the use of non-cationic polymer carriers,by controlling or circumventing the use of cationic materials,represents a promising approach for nucleic acid delivery.In this review,we highlight various designs of non-cationic polymer carriers that go beyond the principle of electrostatic interactions,including conjugation,chemical bonding,physical crosslinking,hydrophobic interactions,and coordination bonding with nucleic acids.Additionally,we discuss strategies for enhancing the efficiency of nucleic acid delivery and therapeutic effects of non-cationic polymer carriers,focusing on targeted delivery,cellular internalization,and endosomal escape.

紧凑城市理论下的停车场分时复用规划设计策略研究

紧凑城市面临的一大主要问题是人与机动车对有限城市土地资源的争夺,而停车基础设施空间的共享使用有望调和这一矛盾。本研究在既有文献的基础上,提出了交通基础设施分时复用的技术框架,并以某地一处老旧城区为例展开应用探索。该系统性规划技术策略主要包括“供需识别-规划设计-社区动员”三大步骤:1)从宏观尺度到微观尺度,结合手机信令数据与实地调研数据,对停车场使用率和居民活动需求特征进行识别;2)基于上述特征制定分时复用规则,进行具体的空间规划设计;3)基于分时复用策略,设计具有实时反馈功能的互动模型,通过引导公众行为保证规划结果的有效实施。综上,本研究回应了土地在空间维度混合利用的局限性,从时间维度出发,结合大数据、实地调研与访谈等途径,融合规划设计和公共参与方法,为减缓城市中的人车矛盾提供了有效的解决思路。

Julolidine functionalized benzimidazoline-doped fullerene derivatives for efficient and stable perovskite solar cells

Fullerene derivatives are highly attractive materials in solar cells,organic thermoelectrics,and other devices.However,the intrinsic low electron mobility and electrical conductivity restrict their potential device performance,such as perovskite solar cells(PSCs).Herein,we successfully enhanced the electric properties and morphology of phenyl-C61-butyric acid methyl ester(PCBM)by n-doping it with a benzimidazoline derivative,9-(1,3-dimethyl-2,3-dihydro-1H-benzoimidazol-2-yl)-julolidine(JLBI-H)via a solution process.We found the n-doping can not only improve the conductivity and optimize the band alignment but also enable the PCBM to have a constantly strong charge extraction ability in a wide temperature from 173 to 373 K,which guarantees a stable photovoltaic performance of the corresponding PSCs under a wide range of operating temperatures.With the JLBI-H-doped PCBM,we improved the efficiency from 17.9%to 19.8%,along with enhanced stability of the nonencapsulated devices following the aging protocol of ISOS-D-1.

Secondary Frequency Control Considering Optimized Power Support From Virtual Power Plant Containing Aluminum Smelter Loads Through VSC-HVDC Link

The growing number of renewable energy replacing conventional generators results in a loss of the reserve for frequency control in power systems,while many industrial power grids often have excess energy supply due to abundant wind and solar energy resources.This paper proposes a secondary frequency control(SFC)strategy that allows industrial power grids to provide emergency high-voltage direct current(HVDC)power support(EDCPS)for emergency to a system requiring power support through a voltage source converter(VSC)HVDC link.An architecture including multiple model predictive control(MPC)controllers with periodic communication is designed to simultaneously obtain optimized EDCPS capacity and minimize adverse effects on the providing power support(PPS)system.Moreover,a model of a virtual power plant(VPP)containing aluminum smelter loads(ASLs)and a high penetration of wind power is established for the PPS system.The flexibility and controllability of the VPP are improved by the demand response of the ASLs.The uncertainty associated with wind power is considered by chance constraints.The effectiveness of the proposed strategy is verified by simulation results using the data of an actual industrial power grid in Inner Mongolia,China.The DC voltage of the VSCs and the DC in the potlines of the ASLs are also investigated in the simulation.

Magnetic-field-driven reverse martensitic transformation with multiple magneto-responsive effects by manipulating magnetic ordering in Fe-doped Co-V-Ga Heusler alloys

Nowadays,searching for the materials with multiple magneto-functional properties and good mechanical properties is vital in various fields,such as solid-state refrigeration,magnetic actuators,magnetic sensors and intelligent/smart devices.In this work,the magnetic-field-induced metamagnetic reverse martensitic transformation(MFIRMT)from paramagnetic martensite to ferromagnetic austenite with multiple magneto-responsive effects is realized in Fe-doped Co-V-Ga Heusler alloys by manipulating the magnetic ordering.The martensitic transformation temperature Tmreduces quasi-linearly with increasing Fe-content.In strikingly contrast with the Fe-free alloys,the magnetization difference(M')across martensitic transformation increases by three orders of magnitude for Fe-doped alloys.The increased M'should be ascribed to the reduction of Tm,almost unchanged Curie temperature of austenite and the increased magnetic moment in the samples with higher Fe-content.The large M'provides strong driving force to realize the MFIRMT and accordingly multiple magneto-responsive effects,such as magnetocaloric,magnetoresistance and magnetostriction effects.Meanwhile,giant Vickers hardness of 518 HV and compressive strength of 1423 MPa are achieved.Multiple magneto-responsive effects with exceptional mechanical properties make these alloys great potential candidates for applications in many fields.

A method of improving ambiguity fixing rate for post-processing kinematic GNSS data

Global Navigation Satellite System precise positioning using carrier phase measurements requires reliable ambiguity resolution.It is challenging to obtain continuous precise positions with a high ambiguity fixing rate under a wide range of dynamic scenes with a single base station,thus the positioning accuracy will be degraded seriously.The Forward-Backward Combination(FBC),a common post-processing smoothing method,is simply the weighted average of the positions of forward and backward filtering.When the ambiguity fixing rate of the one-way(forward or backward)filter is low,the FBC method usually cannot provide accurate and reliable positioning results.Consequently,this paper proposed a method to improve the accuracy of positions by integrating forward and backward AR,which combines the forward and backward ambiguities instead of positions-referred to as ambiguity domain-based integration(ADBI).The purpose of ADBI is to find a reliable correct integer ambiguities by making full use of the integer nature of ambiguities and integrating the ambiguities from the forward and backward filters.Once the integer ambiguities are determined correctly and reliably with ADBI,then the positions are updated with the fixing ambiguities constrained,in which more accurate positions with high confidence can be achieved.The effectiveness of the proposed approach is validated with airborne and car-borne dynamic experiments.The experimental results demonstrated that much better accuracy of position and higher ambiguity-fixed success rate can be achieved than the traditional post-processing method.

Labour market performance of young migrant workers with heterogeneous educational trajectories in China

Successful global cities present a spectrum of development strategies but share the benefit of the reciprocal dynamics between tailored education systems and matching labour markets.This paper examines burgeoning cities in China and investigates the effects of the heterogeneous educational trajectories of young migrant workers in urban China on their labour market performance.Drawing on the National Migrant Dynamics Monitoring Survey,this paper finds striking wage variations among the young migrant population.Migrant workers who attended high schools in current receiving cities earned less than their counterparts who received senior-secondary education elsewhere.Students following the academic track were better off than students following the vocational track.To further explore what has prevented the urban labour market from rewarding migrants who studied in a receiving city,where the education system is expected to better cater to the city’s specific industrial needs,we tested and found evidence of the mediating effects of job industry and occupation.In addition to engaging with empirical debates in the field,this paper develops a theoretical framework to model how the qualitative attributes of an education system affect wage variations among migrant workers.

The Impact of Policy on the Clustering of the Blockchain Industry Evidence from GMM Estimates

Although local governments in China are encouraging the development of blockchain technology,the regional clustering of the blockchain industry still shows obvious differentiation.We use blockchain industry-related data during the period 2012–2019 to calculate the blockchain industrial clustering of each province in China.We find that the clustering state of the blockchain industry is quite different from the state of other industries and the situation of economic development in the same region.In less-developed regions,the blockchain industry is more prominent,which may benefit from local government management.We conduct an empirical analysis on the relationship between blockchain industrial clustering and regional government management using the generalized method of moments(GMM)of a dynamic panel.The results show that government management has a positive promoting effect on local blockchain industrial clustering as a whole,among which the promotion from economy,technology,infrastructure and policy is more significant.