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Clinical efficacy and mechanism study of mid-frequency anti-snoring device in treating moderate obstructive sleep apnea-hypopnea syndrome 被引量:1
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作者 Bao Qian zhan-jun chen +3 位作者 Yong-Sheng Wang Xiao-Yan Hu Xiao-Biao Hu Yong-Hua Zheng 《World Journal of Clinical Cases》 SCIE 2024年第5期942-950,共9页
BACKGROUND Obstructive sleep apnea-hypopnea syndrome(OSAHS)is primarily caused by airway obstruction due to narrowing and blockage in the nasal and nasopha-ryngeal,oropharyngeal,soft palate,and tongue base areas.The m... BACKGROUND Obstructive sleep apnea-hypopnea syndrome(OSAHS)is primarily caused by airway obstruction due to narrowing and blockage in the nasal and nasopha-ryngeal,oropharyngeal,soft palate,and tongue base areas.The mid-frequency anti-snoring device is a new technology based on sublingual nerve stimulation.Its principle is to improve the degree of oropharyngeal airway stenosis in OSAHS patients under mid-frequency wave stimulation.Nevertheless,there is a lack of clinical application and imaging evidence.METHODS We selected 50 patients diagnosed with moderate OSAHS in our hospital between July 2022 and August 2023.They underwent a 4-wk treatment regimen involving the mid-frequency anti-snoring device during nighttime sleep.Following the treatment,we monitored and assessed the sleep apnea quality of life index and Epworth Sleepiness Scale scores.Additionally,we performed computed tomo-graphy scans of the oropharynx in the awake state,during snoring,and while using the mid-frequency anti-snoring device.Cross-sectional area measurements in different states were taken at the narrowest airway point in the soft palate posterior and retrolingual areas.RESULTS Compared to pretreatment measurements,patients exhibited a significant reduction in the apnea-hypopnea index,the percentage of time with oxygen saturation below 90%,snoring frequency,and the duration of the most prolonged apnea event.The lowest oxygen saturation showed a notable increase,and both sleep apnea quality of life index and Epworth Sleepiness Scale scores improved.Oropharyngeal computed tomography scans revealed that in OSAHS patients cross-sectional areas of the oropharyngeal airway in the soft palate posterior area and retrolingual area decreased during snoring compared to the awake state.Conversely,during mid-frequency anti-snoring device treatment,these areas increased compared to snoring.CONCLUSION The mid-frequency anti-snoring device demonstrates the potential to enhance various sleep parameters in patients with moderate OSAHS,thereby improving their quality of life and reducing daytime sleepiness.These therapeutic effects are attributed to the device’s ability to ameliorate the narrowing of the oropharynx in OSAHS patients. 展开更多
关键词 Mid-frequency anti-snoring device Obstructive sleep apnea-hypopnea syndrome Sleep monitoring Oropharyngeal computed tomography Curative effect
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Fe3O4@ZnO@YVO4:Eu^3+磁-光-吸波多功能复合纳米颗粒的制备及其性能研究 被引量:2
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作者 彭红霞 沈梦凡 +3 位作者 陈占军 张蕾 田修营 彭秧锡 《中国科学:化学》 CAS CSCD 北大核心 2018年第5期504-511,共8页
结合溶剂热法和沉淀法以氨基功能化的Fe_3O_4纳米颗粒为磁核,在其表面先后包覆上ZnO层和YVO_4:Eu^(3+)发光层,制得集磁性-发光性-微波热转换性能于一体的Fe_3O_4@ZnO@YVO_4:Eu^(3+)多功能复合纳米颗粒,并对其结构和性能进行了研究.X射... 结合溶剂热法和沉淀法以氨基功能化的Fe_3O_4纳米颗粒为磁核,在其表面先后包覆上ZnO层和YVO_4:Eu^(3+)发光层,制得集磁性-发光性-微波热转换性能于一体的Fe_3O_4@ZnO@YVO_4:Eu^(3+)多功能复合纳米颗粒,并对其结构和性能进行了研究.X射线衍射(XRD)分析表明,Fe_3O_4表面成功包覆上了六方晶系红锌矿ZnO和四方相YVO_4.透射电子显微镜(TEM)照片表明,所得的复合纳米颗粒具有明显的核壳结构和球形形貌,构成核的Fe_3O_4纳米颗粒的尺寸在30~40 nm,Fe_3O_4@ZnO@YVO_4:Eu^(3+)多功能复合纳米颗粒的尺寸约为50~60 nm,壳层厚度约为10 nm.磁性、荧光光谱和微波热转换特性分析表明,该复合纳米颗粒同时具有良好的发光性、较强磁性和独特的微波热转换特性,在药物传输与可控释放领域具有潜在的应用价值. 展开更多
关键词 Fe3O4@ZnO@YVO4:Eu^3+ 磁性 荧光性 微波热转换性
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