Human glioblastomas(GBM)are thought to be initiated by glioma stem-like cells(GSLCs).GSLCs also participate in tumor neovascularization by transdifferentiating into vascular endothelial cells.Here,we report a critical...Human glioblastomas(GBM)are thought to be initiated by glioma stem-like cells(GSLCs).GSLCs also participate in tumor neovascularization by transdifferentiating into vascular endothelial cells.Here,we report a critical role of GSLCs in the formation of vasculogenic mimicry(VM),which defines channels lined by tumor cells to supply nutrients to early growing tumors and展开更多
Open access This is an open access article distributed in accordance with the Creative Commons Attribution Non Commercial(CC BY-NC 4.0)license,which permits others to distribute,remix,adapt,build upon this work non-co...Open access This is an open access article distributed in accordance with the Creative Commons Attribution Non Commercial(CC BY-NC 4.0)license,which permits others to distribute,remix,adapt,build upon this work non-commercially,and license their derivative works on different terms,provided the original work is properly cited and the use is non-commercial.See:http://creativecommons.org/licenses/by nc/4.0/.展开更多
文摘Human glioblastomas(GBM)are thought to be initiated by glioma stem-like cells(GSLCs).GSLCs also participate in tumor neovascularization by transdifferentiating into vascular endothelial cells.Here,we report a critical role of GSLCs in the formation of vasculogenic mimicry(VM),which defines channels lined by tumor cells to supply nutrients to early growing tumors and
文摘Open access This is an open access article distributed in accordance with the Creative Commons Attribution Non Commercial(CC BY-NC 4.0)license,which permits others to distribute,remix,adapt,build upon this work non-commercially,and license their derivative works on different terms,provided the original work is properly cited and the use is non-commercial.See:http://creativecommons.org/licenses/by nc/4.0/.
