In iron-based superconductor Fe(Se,Te), a flat band-like feature near the Fermi level was observed around the Brillouin zone center in the superconducting state. It is under debate whether this is the evidence on the ...In iron-based superconductor Fe(Se,Te), a flat band-like feature near the Fermi level was observed around the Brillouin zone center in the superconducting state. It is under debate whether this is the evidence on the presence of the BCS–BEC[Bardeen–Cooper–Schrieffer(BCS), Bose–Einstein condensation(BEC)] crossover in the superconductor. High-resolution laser-based angle-resolved photoemission measurements are carried out on high quality single crystals of FeSe_(0.45)Te_(0.55) superconductor to address the issue. By employing different polarization geometries, we have resolved and isolated the dyz band and the topological surface band, making it possible to study their superconducting behaviors separately. The dyz band alone does not form a flat band-like feature in the superconducting state and the measured dispersion can be well described by the BCS picture. We find that the flat band-like feature is formed from the combination of the dyz band and the topological surface state band in the superconducting state. These results reveal the origin of the flat band-like feature and rule out the presence of BCS-BEC crossover in Fe(Se,Te) superconductor.展开更多
Winter wheat–summer maize cropping system in the North China Plain often experiences droughtinduced yield reduction in the wheat season and rainwater and nitrogen(N)fertilizer losses in the maize season.This study ai...Winter wheat–summer maize cropping system in the North China Plain often experiences droughtinduced yield reduction in the wheat season and rainwater and nitrogen(N)fertilizer losses in the maize season.This study aimed to identify an optimal interseasonal water-and N-management strategy to alleviate these losses.Four ratios of allocation of 360 kg N ha^(-1)between the wheat and maize seasons under one-time presowing root-zone irrigation(W0)and additional jointing and anthesis irrigation(W2)in wheat and one irrigation after maize sowing were set as follows:N1(120:240),N2(180:180),N3(240:120)and N4(300:60).The results showed that under W0,the N3 treatment produced the highest annual yield,crop water productivity(WPC),and nitrogen partial factor productivity(PFPN).Increased N allocation in wheat under W0 improved wheat yield without affecting maize yield,as surplus nitrate after wheat harvest was retained in the topsoil layers and available for the subsequent maize.Under W2,annual yield was largest in the N2 treatment.The risk of nitrate leaching increased in W2 when N application rate in wheat exceeded that of the N2 treatment,especially in the wet year.Compared to W2N2,the W0N3 maintained 95.2%grain yield over two years.The WPCwas higher in the W0 treatment than in the W2 treatment.Therefore,following limited total N rate,an appropriate fertilizer N transfer from maize to wheat season had the potential of a“triple win”for high annual yield,WPCand PFPN in a water-limited wheat–maize cropping system.展开更多
Promoting more floret primordia within a spike to acquire fertile potential during the differentiation and pre-dimorphism phases is critical for increasing the number of fertile florets per spike(NFFs).However,it is y...Promoting more floret primordia within a spike to acquire fertile potential during the differentiation and pre-dimorphism phases is critical for increasing the number of fertile florets per spike(NFFs).However,it is yet unknown the physiological mechanism regulating the complex and dynamic process.This study aimed to clarify how intra-spike hormones,pigments,and assimilates coordinate with each other to regulate spike morphology and then floret primordia development.A two-year field experiment was conducted with two winter wheat genotypes:N50(big-spike with greater NFFs)and SM22(mediumspike with fewer NFFs).We monitored high temporal and spatial-resolution changes in the number and morphology of floret primordia within a spike,as well as in intra-spike hormones,pigments,and assimilates.Our results revealed that the big-spike genotype had more NFFs than the medium-spike genotype,not only because they had more spikelets,but also because they had greater NFFs mainly at central spikelets.More floret primordia at central spikelets had sufficient time to develop and acquire fertile potential during the differentiation phase(167-176 d after sowing,DAS)and the pre-dimorphism phase(179 DAS)for the big-spike genotype than the medium-spike genotype.Floret primordia with fertile morphology during the pre-dimorphism phase always developed into fertile florets during the dimorphism phase.Those early-developed floret primordia most proximal and intermediate to the rachis in the big-spike genotype developed faster than the medium-spike genotype.Correspondingly,the spike dry matter and pigments(chlorophyll a,chlorophyll b,carotene,and carotenoids)content during 170-182 DAS,auxin(IAA)and cytokinin(CTK)content on 167 DAS were significantly higher in the big-spike genotype than in the medium-spike genotype,while jasmonic acid(JA)content was significantly lower in the big-spike genotype compared to the medium-spike genotype during 167-182 DAS.Since the significant differences in intra-spike hormone content of the two genotypes appear earlier than those in dry matter and pigments,we propose a possible model that helped the N50 genotype(big-spike)to form more fertile florets,taking the intra-spike hormone content as a signaling molecule induced assimilates and pigments synthesis,which accelerated the development of more floret primordia during the differentiation phase and then acquired fertile potential during the pre-dimorphism phase,finally improved the NFFs.Our high temporal and spatial-resolution analysis provides an accurate time window for precision cultivation and effective physiological breeding to improve the number of fertile florets in wheat.展开更多
Nitrogen(N)fertilization is critical for spike and floret development,which affects the number of fertile florets per spike(NFFs).However,the physiological regulation of the floret development process by N fertilizati...Nitrogen(N)fertilization is critical for spike and floret development,which affects the number of fertile florets per spike(NFFs).However,the physiological regulation of the floret development process by N fertilization is largely unknown.A high temporal-resolution investigation of floret primordia number and morphology,dry matter,and N availability was conducted under three N fertilization levels:0(N0),120(N1)and 240(N2)kg ha^(−1).Interestingly,fertile florets at anthesis stage were determined by those floret primordia with meiotic ability at booting stage:meiotic ability was a threshold that predicted whether a floret primordium became fertile or abortive florets.Because the developmental rate of the 4th floret primordium in the central spikelet was accelerated and then they acquired meiotic ability,the NFFs increased gradually as N application increased,but the increase range decreased under N2.There were no differences in spike N concentration among treatments,but leaf N concentration was increased in the N1 and N2 treatments.Correspondingly,dry matter accumulation and N content of the leaf and spike in the N1 and N2 treatments was increased as compared to N0.Clearly,optimal N fertilization increased leaf N availability and transport of assimilates to spikes,and allowed more floret primordia to acquire meiotic ability and become fertile florets,finally increasing NFFs.There was no difference in leaf N concentration between N1 and N2 treatment,whereas soil N concentration at 0–60 cm soil layers was higher in N2 than in N1 treatment,implying that there was still some N fertilization that remained unused.Therefore,improving the leaf’s ability to further use N fertilizer is vital for greater NFFs.展开更多
In high temperature cuprate superconductors,it was found that the superfluid density decreases with the increase of hole doping.One natural question is whether there exists normal fluid in the superconducting state in...In high temperature cuprate superconductors,it was found that the superfluid density decreases with the increase of hole doping.One natural question is whether there exists normal fluid in the superconducting state in the overdoped region.In this paper,we have carried out high-resolution ultra-low temperature laser-based angle-resolved photoemission measurements on a heavily overdoped Bi2212 sample with a T_(c) of 48 K.We find that this heavily overdoped Bi2212 remains in the strong coupling regime with 2Δ_(0)/(k_(B)T_(c))=5.8.The single-particle scattering rate is very small along the nodal direction(~5 meV) and increases as the momentum moves from the nodal to the antinodal regions.A hard superconducting gap opening is observed near the antinodal region with the spectral weight at the Fermi level fully suppressed to zero.The normal fluid is found to be negligibly small in the superconducting state of this heavily overdoped Bi2212.These results provide key information to understand the high T_(c) mechanism in the cuprate superconductors.展开更多
An edge coloring of hypergraph H is a function such that holds for any pair of intersecting edges . The minimum number of colors in edge colorings of H is called the chromatic index of H and is ...An edge coloring of hypergraph H is a function such that holds for any pair of intersecting edges . The minimum number of colors in edge colorings of H is called the chromatic index of H and is denoted by . Erdös, Faber and Lovász proposed a famous conjecture that holds for any loopless linear hypergraph H with n vertices. In this paper, we show that is true for gap-restricted hypergraphs. Our result extends a result of Alesandroni in 2021.展开更多
The spatially-resolved laser-based high-resolution angle resolved photoemission spectroscopy(ARPES) measurements have been performed on the optimally-doped YBa_(2)Cu_(3)O_(7)-σ(Y123) superconductor. For the first tim...The spatially-resolved laser-based high-resolution angle resolved photoemission spectroscopy(ARPES) measurements have been performed on the optimally-doped YBa_(2)Cu_(3)O_(7)-σ(Y123) superconductor. For the first time, we found the region from the cleaved surface that reveals clear bulk electronic properties. The intrinsic Fermi surface and band structures of Y123 were observed. The Fermi surface-dependent and momentum-dependent superconducting gap was determined which is nodeless and consistent with the d+is gap form.展开更多
One of the key features required to realize fault-tolerant quantum computation is the robustness of quantum gates against errors.Since geometric quantum gate is naturally insensitivity to noise,it appears to be a prom...One of the key features required to realize fault-tolerant quantum computation is the robustness of quantum gates against errors.Since geometric quantum gate is naturally insensitivity to noise,it appears to be a promising routine to achieve high-fidelity,robust quantum gates.The implementation of geometric quantum gate however faces some troubles such as its complex interaction among multiple energy levels.Moreover,traditional geometric schemes usually take more time than equivalent dynamical ones.Here,we experimentally demonstrate a geometric gate scheme with the time-optimal control(TOC)technique in a superconducting quantum circuit.With a transmon qubit and operations restricted to two computational levels,we implement a set of geometric gates which exhibit better robustness features against control errors than the dynamical counterparts.The measured fidelities of TOC X gate and X/2 gate are 99.81%and 99.79%respectively.Our work shows a promising routine toward scalable fault-tolerant quantum computation.展开更多
Increased grain yield(GY) and grain protein concentration(GPC) are the two main targets of efforts to improve wheat(Triticum aestivum L.) production in the North China Plain(NCP). We conducted a three-year field exper...Increased grain yield(GY) and grain protein concentration(GPC) are the two main targets of efforts to improve wheat(Triticum aestivum L.) production in the North China Plain(NCP). We conducted a three-year field experiment in the 2014–2017 winter wheat growing seasons to compare the effects of conventional irrigation practice(CI) and micro-sprinkling irrigation combined with nitrogen(N) fertilizer(MSI) on GY, GPC, and protein yield(PY). Across the three years, GY, GPC, and PY increased by 10.5%–16.7%, 5.4%–8.0%, and 18.8%–24.6%, respectively, under MSI relative to CI. The higher GY under MSI was due primarily to increased thousand-kernel weight(TKW). The chlorophyll content of leaves was higher under MSI during the mid–late grain filling period, increasing the contribution of post-anthesis dry matter accumulation to GY, with consequent increases in total dry matter accumulation and harvest index compared to CI. During the mid–late grain filling period, the canopy temperature was markedly lower and the relative humidity was higher under MSI than under CI. The duration and rate of filling during the mid–late grain filling period were also higher under MSI than CI, resulting in higher TKW. MSI increased the contribution of post-anthesis N accumulation to grain N but reduced the pre-anthesis remobilization of N in leaves, the primary site of photosynthetic activity, possibly helping maintain photosynthate production in leaves during grain filling. Total N at maturity was higher under MSI than CI,although there was little difference in N harvest index. The higher GPC under MSI than under CI was due to a larger increase in grain N accumulation than in GY. Overall, MSI simultaneously increased both GY and GPC in winter wheat grown in the NCP.展开更多
Sustainable intensification is an agricultural development direction internationally.However,little is known about the yield sustainability of winter wheat(Triticum aestivum L.)under limited irrigation schemes on the ...Sustainable intensification is an agricultural development direction internationally.However,little is known about the yield sustainability of winter wheat(Triticum aestivum L.)under limited irrigation schemes on the North China Plain(NCP).A 28-year field experiment from 1991 to 2018 at Wuqiao Experimental Station was used to characterize long-term yield,evapotranspiration(ET),and water use efficiency(WUE)trends under three irrigation treatments(W1,irrigation just before sowing;W2,irrigation before sowing and at jointing stage;W3,irrigation before sowing,at jointing stage,and at anthesis).Yield gaps and the effects of genetic improvement,climate change,and climate variables on wheat yield and key phenological stages were estimated using the Agricultural Production Systems Simulator(APSIM)model.Grain yield and WUE of winter wheat increased during the 28 years under the three irrigation treatments,and the upward trend of WUE followed a saturation curve pattern.ET increased slightly.Simulation results showed that genetic improvement dramatically prolonged the phenological stages of vegetative growth period and contributed to yield increase by 0.03%-15.6%.The rapid increase in yield with lower water use was associated mainly with an increase in biomass with genetic improvement and partly with an increase in harvest index.A curvilinear relationship between WUE and yield emphasized the importance of obtaining high yields for high WUE.The yield gaps between potential yield and yield under W1 treatment increased from 1991 to 2018 but were relatively constant for the W2 and W3 treatments.Elevated atmospheric CO_(2) concentration offset the negative effects of temperature increase on yield,leading to minor(-2.3%to 0.3%)changes in yield under climate change.Thus,genetic improvement played a dominant role in yield increase,and limited-irrigation schemes(W2 and W3)can increase wheat yield and promote sustainability of crop production on the NCP.展开更多
Nitrogen(N),a macronutrient essential for plant growth and development,is needed for biosynthesis of protein and starch,which affect grain yield and quality.Application of high-N fertilizer increases plant growth,grai...Nitrogen(N),a macronutrient essential for plant growth and development,is needed for biosynthesis of protein and starch,which affect grain yield and quality.Application of high-N fertilizer increases plant growth,grain yield,and flour quality.In this study,we performed the first comparative analysis of gliadin and glutenin subproteomes during kernel development in the elite Chinese wheat cultivar Zhongmai 175 under high-N conditions by reversed-phase ultra-performance liquid chromatography and twodimensional difference gel electrophoresis(2D-DIGE).Application of high-N fertilizer led to significant increases in gluten macropolymer content,total gliadin and glutenin content,and the accumulation of individual storage protein components.Of 126 differentially accumulated proteins(DAPs)induced by high-N conditions,24 gliadins,12 high-molecularweight glutenins,and 27 low-molecular-weight glutenins were significantly upregulated.DAPs during five kernel developmental stages displayed multiple patterns of accumulation.In particular,gliadins and glutenins showed respectively five and six accumulation patterns.The accumulation of storage proteins under high-N conditions may lead to improved dough properties and bread quality.展开更多
Objective: The aim of the study was to investigate the cancer incidence and mortality in Huai'an area, China, from 2009 to 2011. Methods: The data about cancer incidence and mortality were provided by Huai'an Canc...Objective: The aim of the study was to investigate the cancer incidence and mortality in Huai'an area, China, from 2009 to 2011. Methods: The data about cancer incidence and mortality were provided by Huai'an Cancer Registry, China. Incidence and mortality rates, and standardized rates were calculated by age, gender, areas (urban and rural areas of Huai'an) and cancer sites. Results: The crude incidence rate for all cancer sites was 205.60/105 and the standardized incidence rate was 166.22/10. Both the crude and standardized rates were higher in urban area than in rural area for both sexes. The inci- dence rates increased in people aged 40 and over, and the peak ages of incidence were between 70-75 in both males and females. The crude mortality rate for all cancer sites was 153.88/105 and the standardized mortality rate was 122.14/105. Both the crude and standardized rates were similar in urban and rural areas for both men and women. The mortality rates were at low level under the age 50 in both sexes, but increased after the age 50, reaching the peak at the ages of 80-85 in both males and females. The top 10 most common cancer sites in rank were esophagus, stomach, lung, liver, colon-rectum, breast, pancreas, cervix uteri, brain and central nervous system, and leukemia, accounting for 87.56% of all cancers. The top 10 most leading causes of cancer death in order were cancers of esophagus, lung, liver, stomach, colon-rectum, pancreas, brain and central nervous system, leukemia, breast and lymphoma, accounting for 90.53% of all cancer deaths. Conclusion: Cancer is one kind of major diseases threatening people's health in Huai'an area, China. Cancer prevention and control should be enhanced, especially for esophageal cancer.展开更多
To clarify the active components of Wuzhuyu-tang, this study analyzed dynamic changes of 10 ingredients of Wuzhuyu-tang in plasma using combination high performance liquid chromatography-mass spectrometry after oral a...To clarify the active components of Wuzhuyu-tang, this study analyzed dynamic changes of 10 ingredients of Wuzhuyu-tang in plasma using combination high performance liquid chromatography-mass spectrometry after oral administration in rats. The results showed that seven ingredients were detected in portal vein plasma after oral administration of 16.3 or 8.15 g/kg equivalent of raw material of Wuzhuyu-tang extract. The absorption rate of limonin, evodiamine, gingerol (6-Gi), and ginsenoside-Rg1 was greater than that of isorhamnetin-3-O-β-D-glucosyl (6″→1″′)-α-L-rhamnoside, ginsenoside-Rb1 (Rb1), and ginsenoside-Re (Re). The time most elements were absorbed into the blood was 30 to 60 minutes after administration. Re, 6-Gi and Rb1 were metabolized faster. The results suggest that the seven ingredients described above are the active components for treating migraines.展开更多
Quantum singular value thresholding(QSVT) algorithm,as a core module of many mathematical models,seeks the singular values of a sparse and low rank matrix exceeding a threshold and their associated singular vectors.Th...Quantum singular value thresholding(QSVT) algorithm,as a core module of many mathematical models,seeks the singular values of a sparse and low rank matrix exceeding a threshold and their associated singular vectors.The existing all-qubit QSVT algorithm demands lots of ancillary qubits,remaining a huge challenge for realization on nearterm intermediate-scale quantum computers.In this paper,we propose a hybrid QSVT(HQSVT) algorithm utilizing both discrete variables(DVs) and continuous variables(CVs).In our algorithm,raw data vectors are encoded into a qubit system and the following data processing is fulfilled by hybrid quantum operations.Our algorithm requires O [log(MN)] qubits with0(1) qumodes and totally performs 0(1) operations,which significantly reduces the space and runtime consumption.展开更多
Super-high resolution laser-based angle-resolved photoemission measurements are carried out on LiFeAs superconductor to investigate its electron dynamics. Three energy scales at ~ 20 meV, ~ 34 meV, and ~ 55 meV are re...Super-high resolution laser-based angle-resolved photoemission measurements are carried out on LiFeAs superconductor to investigate its electron dynamics. Three energy scales at ~ 20 meV, ~ 34 meV, and ~ 55 meV are revealed for the first time in the electron self-energy both in the superconducting state and normal state. The ~ 20 meV and ~ 34 meV scales can be attributed to the coupling of electrons with sharp bosonic modes which are most likely phonons. These observations provide definitive evidence on the existence of mode coupling in iron-based superconductors.展开更多
Objective: The aim of our study was to investigate the epidemiological characteristics of esophageal cancer from 2009 to 2011 in Huai'an area, China. Methods: The data about the incidence and mortality of esophage...Objective: The aim of our study was to investigate the epidemiological characteristics of esophageal cancer from 2009 to 2011 in Huai'an area, China. Methods: The data about the incidence and mortality of esophageal cancer were provid- ed by Huai'an Cancer Registry, and the epidemiological characteristics of the disease were analyzed. Results: Esophageal cancer was not only the first most common cancer, but also the leading cause of cancer death in Huai'an area. The crude and standardized incidence rates were 62.91/10 5 and 49.92/10 5 , and the crude and standardized mortality rates were 46.75/10 5 and 36.87/10 5 , respectively. The sex ratio (male-female) was 1.69:1 in incidence, and the incidence increased in people aged 40 years and over, reaching the peak at the ages of 70-75 years. The mortality rate was at low level under the age of 50 years, but increased after the age of 50 years, reaching the peak at the age of 75-85 years. Incidence and mortality rates varied regionally with the highest rate found in Chuzhou district (90.76/10 5 and 67.17/10 5 ) and lowest rate observed in Qinghe district (32.41/10 5 and 8.75/10 5 ). Conclusion: Esophageal cancer is the major burden of cancer in Huai'an area, and has marked geographic distribution difference. The key period of age for screening and prevention of the disease is 55-85 years old.展开更多
The paper introduce segmentation ideas in the pretreatment process of web page. By page segmentation technique to extract the accurate information in the extract region, the region was processed to extract according t...The paper introduce segmentation ideas in the pretreatment process of web page. By page segmentation technique to extract the accurate information in the extract region, the region was processed to extract according to the rules of ontology extraction, and ultimately get the information you need. Through experiments on two real datasets and compare with related work, experimental results show that this method can achieve good extraction results.展开更多
Emerging and recurrent infectious diseases caused by human coronaviruses(HCoVs)continue to pose a significant threat to global public health security.In light of this ongoing threat,the development of a broad-spectrum...Emerging and recurrent infectious diseases caused by human coronaviruses(HCoVs)continue to pose a significant threat to global public health security.In light of this ongoing threat,the development of a broad-spectrum drug to combat HCoVs is an urgently priority.Herein,we report a series of anti-pan-coronavirus ssDNA aptamers screened using Systematic Evolution of Ligands by Exponential Enrichment(SELEX).These aptamers have nanomolar affinity with the nucleocapsid protein(NP)of Severe acute respiratory syndrome coronavirus 2(SARS-CoV-2)and also show excellent binding efficiency to the N proteins of both SARS,MERS,HCoV-OC43 and-NL63 with affinity KD values of 1.31 to 135.36 nM.Such aptamer-based therapeutics exhibited potent antiviral activity against both the authentic SARS-CoV-2 prototype strain and the Omicron variant(BA.5)with EC50 values at 2.00 nM and 41.08 nM,respectively.The protein docking analysis also evidenced that these aptamers exhibit strong affinities for N proteins of pan-coronavirus and other HCoVs(−229E and-HKU1).In conclusion,we have identified six aptamers with a high pan-coronavirus antiviral activity,which could potentially serve as an effective strategy for preventing infections by unknown coronaviruses and addressing the ongoing global health threat.展开更多
基金Projects supported by the National Key Research and Development Program of China(GrantNos.2021YFA1401800,2022YFA1604200,2022YFA1403900,and2023YFA1406000)the National Natural Science Foundation of China(Grant Nos.12488201,12374066,12074411,and 12374154)+3 种基金the Strategic Priority Research Program(B)of the Chinese Academy of Sciences(Grant Nos.XDB25000000 and XDB33000000)the Innovation Program for Quantum Science and Technology(Grant No.2021ZD0301800)the Youth Innovation Promotion Association of the Chinese Academy of Sciences(Grant No.Y2021006)the Synergetic Extreme Condition User Facility(SECUF)。
文摘In iron-based superconductor Fe(Se,Te), a flat band-like feature near the Fermi level was observed around the Brillouin zone center in the superconducting state. It is under debate whether this is the evidence on the presence of the BCS–BEC[Bardeen–Cooper–Schrieffer(BCS), Bose–Einstein condensation(BEC)] crossover in the superconductor. High-resolution laser-based angle-resolved photoemission measurements are carried out on high quality single crystals of FeSe_(0.45)Te_(0.55) superconductor to address the issue. By employing different polarization geometries, we have resolved and isolated the dyz band and the topological surface band, making it possible to study their superconducting behaviors separately. The dyz band alone does not form a flat band-like feature in the superconducting state and the measured dispersion can be well described by the BCS picture. We find that the flat band-like feature is formed from the combination of the dyz band and the topological surface state band in the superconducting state. These results reveal the origin of the flat band-like feature and rule out the presence of BCS-BEC crossover in Fe(Se,Te) superconductor.
基金supported by Hebei Province Key Research Project(21327003D-1)Beijing Science and Technology Planning Project(Z221100006422005)+1 种基金China Postdoctoral Science Foundation(2023M743815)China Agriculture Research System(CARS301)。
文摘Winter wheat–summer maize cropping system in the North China Plain often experiences droughtinduced yield reduction in the wheat season and rainwater and nitrogen(N)fertilizer losses in the maize season.This study aimed to identify an optimal interseasonal water-and N-management strategy to alleviate these losses.Four ratios of allocation of 360 kg N ha^(-1)between the wheat and maize seasons under one-time presowing root-zone irrigation(W0)and additional jointing and anthesis irrigation(W2)in wheat and one irrigation after maize sowing were set as follows:N1(120:240),N2(180:180),N3(240:120)and N4(300:60).The results showed that under W0,the N3 treatment produced the highest annual yield,crop water productivity(WPC),and nitrogen partial factor productivity(PFPN).Increased N allocation in wheat under W0 improved wheat yield without affecting maize yield,as surplus nitrate after wheat harvest was retained in the topsoil layers and available for the subsequent maize.Under W2,annual yield was largest in the N2 treatment.The risk of nitrate leaching increased in W2 when N application rate in wheat exceeded that of the N2 treatment,especially in the wet year.Compared to W2N2,the W0N3 maintained 95.2%grain yield over two years.The WPCwas higher in the W0 treatment than in the W2 treatment.Therefore,following limited total N rate,an appropriate fertilizer N transfer from maize to wheat season had the potential of a“triple win”for high annual yield,WPCand PFPN in a water-limited wheat–maize cropping system.
基金funded by the Scientific and Technological Innovation Team Project of Seed Industry for Saline-alkali Tolerant Crop in Hebei Province(23327501D)the National Key Research and Development Program of China(2022YFD2300802,2022YFD1900703)the China Agriculture Research System(CARS-3).
文摘Promoting more floret primordia within a spike to acquire fertile potential during the differentiation and pre-dimorphism phases is critical for increasing the number of fertile florets per spike(NFFs).However,it is yet unknown the physiological mechanism regulating the complex and dynamic process.This study aimed to clarify how intra-spike hormones,pigments,and assimilates coordinate with each other to regulate spike morphology and then floret primordia development.A two-year field experiment was conducted with two winter wheat genotypes:N50(big-spike with greater NFFs)and SM22(mediumspike with fewer NFFs).We monitored high temporal and spatial-resolution changes in the number and morphology of floret primordia within a spike,as well as in intra-spike hormones,pigments,and assimilates.Our results revealed that the big-spike genotype had more NFFs than the medium-spike genotype,not only because they had more spikelets,but also because they had greater NFFs mainly at central spikelets.More floret primordia at central spikelets had sufficient time to develop and acquire fertile potential during the differentiation phase(167-176 d after sowing,DAS)and the pre-dimorphism phase(179 DAS)for the big-spike genotype than the medium-spike genotype.Floret primordia with fertile morphology during the pre-dimorphism phase always developed into fertile florets during the dimorphism phase.Those early-developed floret primordia most proximal and intermediate to the rachis in the big-spike genotype developed faster than the medium-spike genotype.Correspondingly,the spike dry matter and pigments(chlorophyll a,chlorophyll b,carotene,and carotenoids)content during 170-182 DAS,auxin(IAA)and cytokinin(CTK)content on 167 DAS were significantly higher in the big-spike genotype than in the medium-spike genotype,while jasmonic acid(JA)content was significantly lower in the big-spike genotype compared to the medium-spike genotype during 167-182 DAS.Since the significant differences in intra-spike hormone content of the two genotypes appear earlier than those in dry matter and pigments,we propose a possible model that helped the N50 genotype(big-spike)to form more fertile florets,taking the intra-spike hormone content as a signaling molecule induced assimilates and pigments synthesis,which accelerated the development of more floret primordia during the differentiation phase and then acquired fertile potential during the pre-dimorphism phase,finally improved the NFFs.Our high temporal and spatial-resolution analysis provides an accurate time window for precision cultivation and effective physiological breeding to improve the number of fertile florets in wheat.
基金This study was supported by the National Key Research and Development Program of China(2022YFD1900703,2022YFD2300802)the Earmarked Fund for CARS(CARS-3)+1 种基金the National Natural Science Foundation of China(31871563)China Postdoctoral Science Foundation(2022M723437).
文摘Nitrogen(N)fertilization is critical for spike and floret development,which affects the number of fertile florets per spike(NFFs).However,the physiological regulation of the floret development process by N fertilization is largely unknown.A high temporal-resolution investigation of floret primordia number and morphology,dry matter,and N availability was conducted under three N fertilization levels:0(N0),120(N1)and 240(N2)kg ha^(−1).Interestingly,fertile florets at anthesis stage were determined by those floret primordia with meiotic ability at booting stage:meiotic ability was a threshold that predicted whether a floret primordium became fertile or abortive florets.Because the developmental rate of the 4th floret primordium in the central spikelet was accelerated and then they acquired meiotic ability,the NFFs increased gradually as N application increased,but the increase range decreased under N2.There were no differences in spike N concentration among treatments,but leaf N concentration was increased in the N1 and N2 treatments.Correspondingly,dry matter accumulation and N content of the leaf and spike in the N1 and N2 treatments was increased as compared to N0.Clearly,optimal N fertilization increased leaf N availability and transport of assimilates to spikes,and allowed more floret primordia to acquire meiotic ability and become fertile florets,finally increasing NFFs.There was no difference in leaf N concentration between N1 and N2 treatment,whereas soil N concentration at 0–60 cm soil layers was higher in N2 than in N1 treatment,implying that there was still some N fertilization that remained unused.Therefore,improving the leaf’s ability to further use N fertilizer is vital for greater NFFs.
基金Project supported by the National Natural Science Foundation of China(Grant Nos.12488201,12374066,12074411,and 12374154)the National Key Research and Development Program of China(Grant Nos.2021YFA1401800,2022YFA1604200,2022YFA1403900,and 2023YFA1406000)+3 种基金the Strategic Priority Research Program(B)of the Chinese Academy of Sciences(Grant Nos.XDB25000000 and XDB33000000)the Innovation Program for Quantum Science and Technology(Grant No.2021ZD0301800)the Youth Innovation Promotion Association of the Chinese Academy of Sciences(Grant No.Y2021006)the Synergetic Extreme Condition User Facility(SECUF)。
文摘In high temperature cuprate superconductors,it was found that the superfluid density decreases with the increase of hole doping.One natural question is whether there exists normal fluid in the superconducting state in the overdoped region.In this paper,we have carried out high-resolution ultra-low temperature laser-based angle-resolved photoemission measurements on a heavily overdoped Bi2212 sample with a T_(c) of 48 K.We find that this heavily overdoped Bi2212 remains in the strong coupling regime with 2Δ_(0)/(k_(B)T_(c))=5.8.The single-particle scattering rate is very small along the nodal direction(~5 meV) and increases as the momentum moves from the nodal to the antinodal regions.A hard superconducting gap opening is observed near the antinodal region with the spectral weight at the Fermi level fully suppressed to zero.The normal fluid is found to be negligibly small in the superconducting state of this heavily overdoped Bi2212.These results provide key information to understand the high T_(c) mechanism in the cuprate superconductors.
文摘An edge coloring of hypergraph H is a function such that holds for any pair of intersecting edges . The minimum number of colors in edge colorings of H is called the chromatic index of H and is denoted by . Erdös, Faber and Lovász proposed a famous conjecture that holds for any loopless linear hypergraph H with n vertices. In this paper, we show that is true for gap-restricted hypergraphs. Our result extends a result of Alesandroni in 2021.
基金Project supported by the National Natural Science Foundation of China (Grant Nos. 11888101 and 11974404)the National Key Research and Development Program of China (Grant Nos. 2021YFA1401800 and 2018YFA0704200)+3 种基金the Strategic Priority Research Program (B) of the Chinese Academy of Sciences (Grant Nos. XDB25000000 and XDB33000000)the Youth Innovation Promotion Association of CAS (Grant No. Y2021006)Innovation Program for Quantum Science and Technology (Grant No. 2021ZD0301800)the Synergetic Extreme Condition User Facility (SECUF)。
文摘The spatially-resolved laser-based high-resolution angle resolved photoemission spectroscopy(ARPES) measurements have been performed on the optimally-doped YBa_(2)Cu_(3)O_(7)-σ(Y123) superconductor. For the first time, we found the region from the cleaved surface that reveals clear bulk electronic properties. The intrinsic Fermi surface and band structures of Y123 were observed. The Fermi surface-dependent and momentum-dependent superconducting gap was determined which is nodeless and consistent with the d+is gap form.
基金Project supported by the Key Research and Development Program of Guangdong Province,China(Grant No.2018B030326001)the National Natural Science Foundation of China(Grant Nos.11474152,12074179,U21A20436,and 61521001)the Natural Science Foundation of Jiangsu Province,China(Grant No.BE2021015-1)。
文摘One of the key features required to realize fault-tolerant quantum computation is the robustness of quantum gates against errors.Since geometric quantum gate is naturally insensitivity to noise,it appears to be a promising routine to achieve high-fidelity,robust quantum gates.The implementation of geometric quantum gate however faces some troubles such as its complex interaction among multiple energy levels.Moreover,traditional geometric schemes usually take more time than equivalent dynamical ones.Here,we experimentally demonstrate a geometric gate scheme with the time-optimal control(TOC)technique in a superconducting quantum circuit.With a transmon qubit and operations restricted to two computational levels,we implement a set of geometric gates which exhibit better robustness features against control errors than the dynamical counterparts.The measured fidelities of TOC X gate and X/2 gate are 99.81%and 99.79%respectively.Our work shows a promising routine toward scalable fault-tolerant quantum computation.
基金supported by the National Key Research and Development Program of China (2016YFD0300401)the National Natural Science Foundation of China (32001474, 31871563)the China Agriculture Research System (CARS-3)。
文摘Increased grain yield(GY) and grain protein concentration(GPC) are the two main targets of efforts to improve wheat(Triticum aestivum L.) production in the North China Plain(NCP). We conducted a three-year field experiment in the 2014–2017 winter wheat growing seasons to compare the effects of conventional irrigation practice(CI) and micro-sprinkling irrigation combined with nitrogen(N) fertilizer(MSI) on GY, GPC, and protein yield(PY). Across the three years, GY, GPC, and PY increased by 10.5%–16.7%, 5.4%–8.0%, and 18.8%–24.6%, respectively, under MSI relative to CI. The higher GY under MSI was due primarily to increased thousand-kernel weight(TKW). The chlorophyll content of leaves was higher under MSI during the mid–late grain filling period, increasing the contribution of post-anthesis dry matter accumulation to GY, with consequent increases in total dry matter accumulation and harvest index compared to CI. During the mid–late grain filling period, the canopy temperature was markedly lower and the relative humidity was higher under MSI than under CI. The duration and rate of filling during the mid–late grain filling period were also higher under MSI than CI, resulting in higher TKW. MSI increased the contribution of post-anthesis N accumulation to grain N but reduced the pre-anthesis remobilization of N in leaves, the primary site of photosynthetic activity, possibly helping maintain photosynthate production in leaves during grain filling. Total N at maturity was higher under MSI than CI,although there was little difference in N harvest index. The higher GPC under MSI than under CI was due to a larger increase in grain N accumulation than in GY. Overall, MSI simultaneously increased both GY and GPC in winter wheat grown in the NCP.
基金supported by the National Natural Science Foundation of China(31871563)China Agriculture Research System of MOF and MARA(CARS-3)Ministerial and Provincial Co-Innovation Centre for Endemic Crops Production with High-quality and Efficiency in Loess Plateau(SBGJXTZX-44)。
文摘Sustainable intensification is an agricultural development direction internationally.However,little is known about the yield sustainability of winter wheat(Triticum aestivum L.)under limited irrigation schemes on the North China Plain(NCP).A 28-year field experiment from 1991 to 2018 at Wuqiao Experimental Station was used to characterize long-term yield,evapotranspiration(ET),and water use efficiency(WUE)trends under three irrigation treatments(W1,irrigation just before sowing;W2,irrigation before sowing and at jointing stage;W3,irrigation before sowing,at jointing stage,and at anthesis).Yield gaps and the effects of genetic improvement,climate change,and climate variables on wheat yield and key phenological stages were estimated using the Agricultural Production Systems Simulator(APSIM)model.Grain yield and WUE of winter wheat increased during the 28 years under the three irrigation treatments,and the upward trend of WUE followed a saturation curve pattern.ET increased slightly.Simulation results showed that genetic improvement dramatically prolonged the phenological stages of vegetative growth period and contributed to yield increase by 0.03%-15.6%.The rapid increase in yield with lower water use was associated mainly with an increase in biomass with genetic improvement and partly with an increase in harvest index.A curvilinear relationship between WUE and yield emphasized the importance of obtaining high yields for high WUE.The yield gaps between potential yield and yield under W1 treatment increased from 1991 to 2018 but were relatively constant for the W2 and W3 treatments.Elevated atmospheric CO_(2) concentration offset the negative effects of temperature increase on yield,leading to minor(-2.3%to 0.3%)changes in yield under climate change.Thus,genetic improvement played a dominant role in yield increase,and limited-irrigation schemes(W2 and W3)can increase wheat yield and promote sustainability of crop production on the NCP.
基金financially supported by the National Key Research and Development Program of China(2016YFD0100502)the National Natural Science Foundation of China(31171773)
文摘Nitrogen(N),a macronutrient essential for plant growth and development,is needed for biosynthesis of protein and starch,which affect grain yield and quality.Application of high-N fertilizer increases plant growth,grain yield,and flour quality.In this study,we performed the first comparative analysis of gliadin and glutenin subproteomes during kernel development in the elite Chinese wheat cultivar Zhongmai 175 under high-N conditions by reversed-phase ultra-performance liquid chromatography and twodimensional difference gel electrophoresis(2D-DIGE).Application of high-N fertilizer led to significant increases in gluten macropolymer content,total gliadin and glutenin content,and the accumulation of individual storage protein components.Of 126 differentially accumulated proteins(DAPs)induced by high-N conditions,24 gliadins,12 high-molecularweight glutenins,and 27 low-molecular-weight glutenins were significantly upregulated.DAPs during five kernel developmental stages displayed multiple patterns of accumulation.In particular,gliadins and glutenins showed respectively five and six accumulation patterns.The accumulation of storage proteins under high-N conditions may lead to improved dough properties and bread quality.
基金Supported by the grants of Medical Science and Technology Innovation Foundation of Nanjing Military Command of Chinese People’s Liberation Army (No. 08MA036)Jiangsu Province Preventive Medicine Foundation (No. YZ201008)
文摘Objective: The aim of the study was to investigate the cancer incidence and mortality in Huai'an area, China, from 2009 to 2011. Methods: The data about cancer incidence and mortality were provided by Huai'an Cancer Registry, China. Incidence and mortality rates, and standardized rates were calculated by age, gender, areas (urban and rural areas of Huai'an) and cancer sites. Results: The crude incidence rate for all cancer sites was 205.60/105 and the standardized incidence rate was 166.22/10. Both the crude and standardized rates were higher in urban area than in rural area for both sexes. The inci- dence rates increased in people aged 40 and over, and the peak ages of incidence were between 70-75 in both males and females. The crude mortality rate for all cancer sites was 153.88/105 and the standardized mortality rate was 122.14/105. Both the crude and standardized rates were similar in urban and rural areas for both men and women. The mortality rates were at low level under the age 50 in both sexes, but increased after the age 50, reaching the peak at the ages of 80-85 in both males and females. The top 10 most common cancer sites in rank were esophagus, stomach, lung, liver, colon-rectum, breast, pancreas, cervix uteri, brain and central nervous system, and leukemia, accounting for 87.56% of all cancers. The top 10 most leading causes of cancer death in order were cancers of esophagus, lung, liver, stomach, colon-rectum, pancreas, brain and central nervous system, leukemia, breast and lymphoma, accounting for 90.53% of all cancer deaths. Conclusion: Cancer is one kind of major diseases threatening people's health in Huai'an area, China. Cancer prevention and control should be enhanced, especially for esophageal cancer.
基金the Scientific Research Program of Beijing Municipal Education Commission-Capital Key Research Program of Chinese Medicine and Nursing, No. 10ZYH01the Supporting Program of the "Eleventh Five-year Plan" for Science and Technology Research of China, No.2006BAI08B03
文摘To clarify the active components of Wuzhuyu-tang, this study analyzed dynamic changes of 10 ingredients of Wuzhuyu-tang in plasma using combination high performance liquid chromatography-mass spectrometry after oral administration in rats. The results showed that seven ingredients were detected in portal vein plasma after oral administration of 16.3 or 8.15 g/kg equivalent of raw material of Wuzhuyu-tang extract. The absorption rate of limonin, evodiamine, gingerol (6-Gi), and ginsenoside-Rg1 was greater than that of isorhamnetin-3-O-β-D-glucosyl (6″→1″′)-α-L-rhamnoside, ginsenoside-Rb1 (Rb1), and ginsenoside-Re (Re). The time most elements were absorbed into the blood was 30 to 60 minutes after administration. Re, 6-Gi and Rb1 were metabolized faster. The results suggest that the seven ingredients described above are the active components for treating migraines.
基金Project supported by the Key Research and Development Program of Guangdong Province,China(Grant No.2018B030326001)the National Natural Science Foundation of China(Grant Nos.61521001,12074179,and 11890704)。
文摘Quantum singular value thresholding(QSVT) algorithm,as a core module of many mathematical models,seeks the singular values of a sparse and low rank matrix exceeding a threshold and their associated singular vectors.The existing all-qubit QSVT algorithm demands lots of ancillary qubits,remaining a huge challenge for realization on nearterm intermediate-scale quantum computers.In this paper,we propose a hybrid QSVT(HQSVT) algorithm utilizing both discrete variables(DVs) and continuous variables(CVs).In our algorithm,raw data vectors are encoded into a qubit system and the following data processing is fulfilled by hybrid quantum operations.Our algorithm requires O [log(MN)] qubits with0(1) qumodes and totally performs 0(1) operations,which significantly reduces the space and runtime consumption.
基金Project supported by the National Key Research and Development Program of China(Grant Nos.2016YFA0300300,2016YFA0300600,2017YFA0302900,2018YFA0704200,2018YFA0305600,and 2019YFA0308000)the National Natural Science Foundation of China(Grant Nos.11888101,11922414,and 11874405)+2 种基金the Strategic Priority Research Program(B)of the Chinese Academy of Sciences(Grant Nos.XDB25000000 and XDB33010300)the Youth Innovation Promotion Association of the Chinese Academy of Sciences(Grant No.2017013)the Research Program of Beijing Academy of Quantum Information Sciences(Grant No.Y18G06)。
文摘Super-high resolution laser-based angle-resolved photoemission measurements are carried out on LiFeAs superconductor to investigate its electron dynamics. Three energy scales at ~ 20 meV, ~ 34 meV, and ~ 55 meV are revealed for the first time in the electron self-energy both in the superconducting state and normal state. The ~ 20 meV and ~ 34 meV scales can be attributed to the coupling of electrons with sharp bosonic modes which are most likely phonons. These observations provide definitive evidence on the existence of mode coupling in iron-based superconductors.
基金Supported by grants from the Medical Science and Technology Innovation Foundation of Nanjing Military Command of Chinese People’s Liberation Army (No. 08MA036)Jiangsu Province Preventive Medicine Foundation (No. YZ201008)
文摘Objective: The aim of our study was to investigate the epidemiological characteristics of esophageal cancer from 2009 to 2011 in Huai'an area, China. Methods: The data about the incidence and mortality of esophageal cancer were provid- ed by Huai'an Cancer Registry, and the epidemiological characteristics of the disease were analyzed. Results: Esophageal cancer was not only the first most common cancer, but also the leading cause of cancer death in Huai'an area. The crude and standardized incidence rates were 62.91/10 5 and 49.92/10 5 , and the crude and standardized mortality rates were 46.75/10 5 and 36.87/10 5 , respectively. The sex ratio (male-female) was 1.69:1 in incidence, and the incidence increased in people aged 40 years and over, reaching the peak at the ages of 70-75 years. The mortality rate was at low level under the age of 50 years, but increased after the age of 50 years, reaching the peak at the age of 75-85 years. Incidence and mortality rates varied regionally with the highest rate found in Chuzhou district (90.76/10 5 and 67.17/10 5 ) and lowest rate observed in Qinghe district (32.41/10 5 and 8.75/10 5 ). Conclusion: Esophageal cancer is the major burden of cancer in Huai'an area, and has marked geographic distribution difference. The key period of age for screening and prevention of the disease is 55-85 years old.
文摘The paper introduce segmentation ideas in the pretreatment process of web page. By page segmentation technique to extract the accurate information in the extract region, the region was processed to extract according to the rules of ontology extraction, and ultimately get the information you need. Through experiments on two real datasets and compare with related work, experimental results show that this method can achieve good extraction results.
基金supported by the National Key Research&Development Program of China(2021YFA1201000,2021YFC2302400,2023YFC2606004)the Guangxi Science and Technology Development Program(AB20117001)+5 种基金the National Natural Science Foundation of China(82204263,32171394,32001008)the Fundamental Research Funds for the Central Universities(3332022055,2022CX01013)the China Postdoctoral Science Foundation(2022M720438)the Beijing Nova Program(Interdisciplinary Cooperation Project)from Beijing Municipal Science&Technology Commission(20220484207)We knowledge the Beijing Institute of Technology Research Fund Program for Young Scholars(XSQD-6120220072)We thank the Biological and Medical Engineering Core Facilities,and Analysis&Testing Center,Beijing Institute of Technology for supporting experimental equipment,and staffs for valuable help with technical support.
文摘Emerging and recurrent infectious diseases caused by human coronaviruses(HCoVs)continue to pose a significant threat to global public health security.In light of this ongoing threat,the development of a broad-spectrum drug to combat HCoVs is an urgently priority.Herein,we report a series of anti-pan-coronavirus ssDNA aptamers screened using Systematic Evolution of Ligands by Exponential Enrichment(SELEX).These aptamers have nanomolar affinity with the nucleocapsid protein(NP)of Severe acute respiratory syndrome coronavirus 2(SARS-CoV-2)and also show excellent binding efficiency to the N proteins of both SARS,MERS,HCoV-OC43 and-NL63 with affinity KD values of 1.31 to 135.36 nM.Such aptamer-based therapeutics exhibited potent antiviral activity against both the authentic SARS-CoV-2 prototype strain and the Omicron variant(BA.5)with EC50 values at 2.00 nM and 41.08 nM,respectively.The protein docking analysis also evidenced that these aptamers exhibit strong affinities for N proteins of pan-coronavirus and other HCoVs(−229E and-HKU1).In conclusion,we have identified six aptamers with a high pan-coronavirus antiviral activity,which could potentially serve as an effective strategy for preventing infections by unknown coronaviruses and addressing the ongoing global health threat.