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Superficial Angiomyxoma of the Vulva: A Case Report
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作者 zo irène raivoherivony Herilalao Elisabeth Razafindrafara +2 位作者 Vahatra Joëlle Razafimahefa Romuald Randriamahavonjy Nantenaina Soa Randrianjafisamindrakotroka 《Open Journal of Pathology》 2024年第2期64-68,共5页
Superficial angiomyxoma is a rare benign mesenchymal tumor that mainly occurs in the genital region. We report the case of a 51-year-old woman with a painless vulvar mass, well circumscribed on ultrasound. On gross fi... Superficial angiomyxoma is a rare benign mesenchymal tumor that mainly occurs in the genital region. We report the case of a 51-year-old woman with a painless vulvar mass, well circumscribed on ultrasound. On gross finding, it was a polypoid and bilobed mass, partially encapsulated. On histological examination, it was a proliferation of non-atypical spindle cells with an abundant, myxoid stroma and numerous medium-sized blood vessels. The diagnosis was superficial angiomyxoma. The clinical features do not often lead to the diagnosis of superficial vulvar angiomyxoma. It is based on histological examination and immunohistochemistry is helpful to differentiate it from other myxoid tumors. 展开更多
关键词 ANGIOMYXOMA Mesenchymal Tumor Myxoïd Stromal Tumor of Vulva
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Undifferentiated Uterine Sarcoma: A Rare Cause of Pelvic Pain in Young Woman
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作者 Fenohery Nalisoa Rakotondrainibe zo irène raivoherivony Nantenaina Soa Randrianjafisamindrakotroka 《Open Journal of Pathology》 2019年第4期71-75,共5页
We report a case of undifferentiated uterine sarcoma occurring in a 20-year-old woman presenting as a pelvic pain with a mass discovered at the physical examination. The tumor ruptured into the abdominal cavity. A tot... We report a case of undifferentiated uterine sarcoma occurring in a 20-year-old woman presenting as a pelvic pain with a mass discovered at the physical examination. The tumor ruptured into the abdominal cavity. A total hysterectomy was performed. On the pathological examination, the uterine corpus presents a proliferation of markedly atypical spindle cells admixed with round cells and pleomorphic cells. The tumor deeply infiltrated the myometrium. The tumor was very necrotizing. There were more than 50 mitoses per 10 fields at high magnification. The isthmus was invaded by the tumor. The diagnosis of undifferentiated uterine sarcoma was confirmed by immunohistochemistry. The tumor shows negativity for the following markers: CKAE1/AE3, h-caldesmon, α-SMA, progesterone receptors, desmin, CD 10, alpha foeto-protein, CD 3 and CD 20. 展开更多
关键词 SARCOMA ENDOMETRIAL Stroma UTERINE SARCOMA
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Invasive Mole of the Uterus: A Case Report
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作者 Herilalao Elisabeth Razafindrafara zo irène raivoherivony +3 位作者 Joëlle Razafimahefa Vahatra Nomeharisoa Rodrigue Emile Hasiniatsy Romuald Randriamahavonjy Nantenaina Soa Randrianjafisamindrakotroka 《Open Journal of Pathology》 CAS 2022年第4期177-182,共6页
Invasive mole is a rare subgroup of gestational trophoblastic disease characterized by the invasion of molar tissue into the myometrium or uterine vasculature. In this paper, we report the third case of invasive mole ... Invasive mole is a rare subgroup of gestational trophoblastic disease characterized by the invasion of molar tissue into the myometrium or uterine vasculature. In this paper, we report the third case of invasive mole described in the Malagasy literature. A 33-year-old woman was referred to the Soavinandriana Hospital, her complaint was persistent vaginal bleeding during 2 months, occurring at 3 months of pregnancy with biological anemia without hemodynamic repercussions. The human chorionic gonadotropin (HCG) level was 385,931 mIU/ml. A haemostasis hysterectomy was performed. Histological examination showed an enlarged uterus and endometrial cavity containing edematous chorionic villi with trophoblastic proliferation invading the myometrium. The diagnosis was an invasive mole, stage I, FIGO score 6. Chemotherapy was prescribed but was not honored. After 45 days of follow-up, the serum βHCG level decreased to 1803 mIU/ml, without clinical symptoms. The patient then lost sight. Persistent vaginal bleeding after pregnancy may be the only clinical symptom of an invasive mole and should raise suspicion. Histological examination establishes the diagnosis. As this is an unusual cause of vaginal bleeding, our case should remind physicians that when faced with this symptom, the possibility of an invasive mole should be considered in order to make an early diagnosis for less aggressive treatment. 展开更多
关键词 Hydatiform Mole Gestational Trophoblastic Disease Invasive Mole Madagascar
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Primary Bilateral Adenocarcinoma of the Fallopian Tube: A Case Report
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作者 zo irène raivoherivony Lalaina Nomenjanahary +1 位作者 Fenohery Nalisoa Rakotondrainibe Nantenaina Soa Randrianjafisamindrakotroka 《Open Journal of Pathology》 CAS 2022年第4期140-145,共6页
Primary fallopian tube carcinoma is an uncommon malignancy that accounts for 0.14% to 1.8% of gynecological cancers. The clinical symptom is not specific and preoperative diagnosis is easy to miss or delay because of ... Primary fallopian tube carcinoma is an uncommon malignancy that accounts for 0.14% to 1.8% of gynecological cancers. The clinical symptom is not specific and preoperative diagnosis is easy to miss or delay because of a lack of specific symptoms. We reported a case of bilateral adenocarcinoma of the Fallopian tubes, was occurred in a 51-year-old postmenopausal woman and diagnosed with bilateral salpingectomy for suspicious of suppurative salpingitis. The diagnosis is not always suspected preoperatively. They are assimilated to salpingitis in the early stage, or to ovarian tumors in the advanced stage. The diagnosis is made postoperatively, after an anatomopathological examination. Its etiology is still poorly understood. 展开更多
关键词 ADENOCARCINOMA Fallopian Tube Madagascar Tubal Carcinoma
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Appendicular Abscess Revealing Gastrointestinal Stromal Tumor of the Appendix
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作者 Lalaina Nomenjanahary zo irène raivoherivony +1 位作者 Adriana Tongavelona Randrianjafisamindrakotroka Nantenaina Soa 《Open Journal of Pathology》 2021年第4期115-119,共5页
Gastrointestinal stromal tumor (GIST) is a rare tumor of the digestive tract, but it is the most common of the mesenchymal tumors. The location is often gastric and small intestine. GIST of the appendix is extremely r... Gastrointestinal stromal tumor (GIST) is a rare tumor of the digestive tract, but it is the most common of the mesenchymal tumors. The location is often gastric and small intestine. GIST of the appendix is extremely rare. We report one case in a 48-year-old man. He complained of severe pain in the right iliac region. The clinical presentation was typically like acute appendicitis. Abdominal ultrasound was performed and suspected an appendicular abscess. Surgical excision of the appendix was performed and histological diagnosis was “gastrointestinal stromal tumor of the appendix”. 展开更多
关键词 GIST APPENDIX PATHOLOGY Antananarivo
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Endometriosis of the Sigmoid Colon Mimicking Malignant Lesion
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作者 Lalaina Nomenjanahary zo irène raivoherivony +1 位作者 Holy Tiana Andrianjafitrimo Nantenaina Soa Randrianjafisamindrakotroka 《Open Journal of Pathology》 2021年第4期110-114,共5页
Endometriosis is defined as the presence of endometrial tissue outside the uterus. It is a benign pathology involving 15% of women of reproductive age. The sigmoid site represents 7% of endometriosis but it is the mos... Endometriosis is defined as the presence of endometrial tissue outside the uterus. It is a benign pathology involving 15% of women of reproductive age. The sigmoid site represents 7% of endometriosis but it is the most frequent area in the digestive tract. We report two cases of colonic endometriosis in which the initial diagnosis suspected a malignant disease. Respectively, the patients were 31 and 48 years old. The first patient complained about abdominal pain with symptoms of intestinal obstruction and was classified after radiological examination as an intrasigmoid tumor with bladder adhesion. The second patient was undergone for a radiological examination because of a bowel obstruction syndrom and a mass in the sigmoid colon was suspected. In both cases, sigmoid colon resection was performed and histological diagnosis was sigmoid endometriosis. Sigmoid endometriosis is rarely diagnosed before surgical excision. Suspicious bowel obstruction and malignant origin lead to large surgical excision. Histological examination is important to establish the diagnosis. 展开更多
关键词 Endometrial Mucosa ENDOMETRIOSIS Sigmoid Endometriosis
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Primary Breast Tuberculosis Mimicking Carcinomatous Mastitis: A Case Report
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作者 zo irène raivoherivony Lalaina Nomenjanahary +1 位作者 Fenohery Nalisoa Rakotondrainibe Nantenaina Soa Randrianjafisamindrakotroka 《Open Journal of Pathology》 2021年第3期79-83,共5页
<span style="font-family:Verdana;">The breast is a rare localization of extra-pulmonary tuberculosis, even in highly endemic countries. It is most often primitive. The clinical and radiological feature... <span style="font-family:Verdana;">The breast is a rare localization of extra-pulmonary tuberculosis, even in highly endemic countries. It is most often primitive. The clinical and radiological features are sometimes misleading. It poses diagnostic problems especially with cancer. We report a case of breast tuberculosis having clinical and radiological presentations as a breast carcinoma. Through this observation and a review of the literature, we provide an update on the epidemiological characteristics and the means of diagnosis of this lesion. It was a 52-year-old woman with inflammatory lump of the left breast, adherent to the skin. Ultrasonography and mammography revealed a homogeneous, poorly demarcated nodule of approximately 4 cm of diameter, classified ACR4. Surgical excision was performed. The histological diagnosis was breast tuberculosis. The diagnosis of tuberculous mastitis is made on bacteriological and pathological examinations. Histological examination helps for diagnostic confirmation while excluding a malignant lesion of the breast.</span> 展开更多
关键词 MASTITIS Breast Disease Extra-Pulmonary Tuberculosis
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