Changes in brain functional network connectivity after stroke

Studies have shown that functional network connection models can be used to study brain net- work changes in patients with schizophrenia. In this study, we inferred that these models could also be used to explore functional network connectivity changes in stroke patients. We used independent component analysis to find the motor areas of stroke patients, which is a novel way to determine these areas. In this study, we collected functional magnetic resonance imaging datasets from healthy controls and right-handed stroke patients following their first ever stroke. Using independent component analysis, six spatially independent components highly correlat- ed to the experimental paradigm were extracted. Then, the functional network connectivity of both patients and controls was established to observe the differences between them. The results showed that there were 11 connections in the model in the stroke patients, while there were only four connections in the healthy controls. Further analysis found that some damaged connections may be compensated for by new indirect connections or circuits produced after stroke. These connections may have a direct correlation with the degree of stroke rehabilitation. Our findings suggest that functional network connectivity in stroke patients is more complex than that in hea- lthy controls, and that there is a compensation loop in the functional network following stroke. This implies that functional network reorganization plays a very important role in the process of rehabilitation after stroke.

Brain functional network connectivity based on a visual task: visual information processing-related brain regions are significantly activated in the task state

It is not clear whether the method used in functional brain-network related research can be applied to explore the feature binding mechanism of visual perception. In this study, we inves-tigated feature binding of color and shape in visual perception. Functional magnetic resonance imaging data were collected from 38 healthy volunteers at rest and while performing a visual perception task to construct brain networks active during resting and task states. Results showed that brain regions involved in visual information processing were obviously activated during the task. The components were partitioned using a greedy algorithm, indicating the visual network existed during the resting state.Z-values in the vision-related brain regions were calculated, conifrming the dynamic balance of the brain network. Connectivity between brain regions was determined, and the result showed that occipital and lingual gyri were stable brain regions in the visual system network, the parietal lobe played a very important role in the binding process of color features and shape features, and the fusiform and inferior temporal gyri were crucial for processing color and shape information. Experimental ifndings indicate that understanding visual feature binding and cognitive processes will help establish computational models of vision, improve image recognition technology, and provide a new theoretical mechanism for feature binding in visual perception.

IEEE 802.16中改进的QoS调度算法设计

IEEE802.16标准在每个节点处都提供实时业务和非实时业务。由于基于优先级的业务的服务质量(QoS)的需求不同,因此需要对传统的调度算法进行改进使其具有更大的适应性。为了改善QoS端到端时延的性能,提出了一种混合调度算法(EDD和WFQ算法相结合)。仿真结果表明:在每个节点处,提出的混合算法比仅使用EDD算法能给实时业务产生的时延更少,并且还能够使单个BS在可允许的端到端时延范围内容纳数量更多的子SS,而且使用从BS到SS的GPSS模式的调度机制比使用GPC模式能产生更小的时延。

政治关联、政府补助与技术创新投入关系研究

基于政治关联视角,以沪深两市信息技术行业上市公司为研究对象,分析政治关联、政府补助与技术创新投入三者之间的关系。研究发现,政治关联、政府补助均对信息技术行业技术创新投入具有正向显著作用。政治关联可以分为两种类型:代表委员类政治关联与政府官员类政治关联。研究表明两种类型的政治关联对技术创新投入力度的作用机制不同。政治关联利用政府补助的中介作用正向作用于信息技术行业的技术创新投入,代表委员类政治关联发挥一定的调节作用。

丹参酮ⅡA抑制心肌细胞的纤维化

背景:转化生长因子β-Smads信号通路是心肌纤维化的关键通路;丹参酮ⅡA具有抑制心肌纤维化作用。目的:验证丹参酮ⅡA对转化生长因子β1致心肌纤维化的作用并探讨其机制。方法:取出生24h内的SD大鼠心脏,利用酶消化法结合差速贴壁体外培养心肌成纤维细胞。取上述第3代心肌成纤维细胞,用5μg/L转化生长因子β1培养15,30,60,120min或6,12,24h后收集细胞,用不同浓度(10-5mol/L、10-4mol/L)丹参酮ⅡA预处理2h后再加入5μg/L转化生长因子β1培养120min或24h后收集细胞,并设空白对照组。免疫细胞化学染色法进行细胞鉴定,反转录聚合酶链反应检测结缔组织生长因子及Ⅰ型胶原蛋白mRNA表达,Western Blot检测Smad7及磷酸化Smad3蛋白表达。免疫组织化学染色及免疫荧光法检测磷酸化Smad3、结缔组织生长因子及Ⅰ型胶原蛋白表达。结果与结论:转化生长因子β1在一定范围内以时间依赖方式诱导结缔组织生长因子、Ⅰ型胶原、磷酸化Smad3及Smad7的表达,刺激终末结缔组织生长因子、Ⅰ型胶原mRNA的表达量明显上升(均P<0.01);磷酸化Smad3及Smad7蛋白表达量在刺激后1h达到峰值,表达量显著增加(均P<0.01)。高浓度丹参酮ⅡA预处理可显著下调磷酸化Smad3、结缔组织生长因子及Ⅰ型胶原表达(均P<0.01)。两种浓度的丹参酮ⅡA预处理均可上调Smad7蛋白表达(P<0.05,P<0.01)。提示丹参酮ⅡA对心肌纤维化有抑制作用,可能与其上调Smad7蛋白表达,抑制转化生长因子β1诱导的Smad3磷酸化,部分阻断转化生长因子β1-Smads信号通路有关。

针刺过程中的针体受力分布

背景:针刺过程针体受力分布,不仅取决于不同穴位处组织结构,更受行针手法的影响。目的:就一般穴位所共有的表皮、真皮和皮下结缔组织的组织结构和力学性质,分提插和捻转法进行针体受力研究。方法:以提插法和捻转法为前提,以表皮组织、真皮组织和皮下结缔组织为区域对象,在前期研究的基础上建立类固体和软物质两种生物力学模型,对行针过程中的针体阻力分布进行分析,以得出定性化的结论。结果与结论:表皮无血管无神经,致密而坚硬,可以看作类固体;真皮及皮下结缔组织中血管神经等分布广泛,疏松而柔软,是典型的软物质。提插行针过程中非"得气"时阻力主要来自表皮部分,在"得气"状况下阻力应该来自表皮和结缔组织中的纤维细胞共同作用,对针体而言,进入皮肤的所有针体部分都是受力点,只是靠近针尖部分的针体受力稍大一些,但是随着提插操作,进入皮肤的针体长度不断在发生变化。捻转法行针的主要阻力来自胶原纤维和弹性纤维的缠绕,对针体而言受力点主要集中在针尖及附近部位。

基于PDMA的5G NR低功耗大连接免调度算法

在5G低功耗大连接场景下,一个小区内存在着数量非常多的UE,并且每个UE传输速率、每次传输的传输块并不大,所以PDCCH信道能够承载的DCI数量就成为增加UE连接数的主要瓶颈,为了降低对PDCCH的DCI数量需求,基于上行的基于PDMA的非正交多址接入技术和免授权调度结合的传输方案,提出此资源分配方案,通过初步系统仿真,相同参数情况下频谱效率可提高到LTE的200%~300%,上行调度过程占用控制信道资源至少降低30%。此外,对于发生碰撞的UE,初传均为免授权,重传时采用授权调度,通过优化PDCCH搜索空间,UE能耗至少降低14%。

CHROMOSPHERIC OBSERVATION AND PRELIMIN ARYALALYSIS OF ACTIVE REGION AR5629 AT URUMQI ASTRONOMICAL STATION

The active region AR5629 had looked quiet since it appeared from east limb onAug. 4th, there were some faculae aronud sunspot, two long filaments connected with thesunspot. On 9th, the filaments in active region became short and arched, We observedtwo class S flares, one of them (1005 UT) was SF / C3. 2 class. On 10th, we took

高压应急柴油发电机组并网控制的实现

本文介绍高压应急发电机组并网控制的实现。说明基于GPC和PLC的系统总体硬件构成,给出了GPC和PLC并网控制思路和方法。

财政分权、企业寻租与地方政府补助——来自中国资本市场的经验证据

文章利用2007-2010年我国A股上市公司数据,实证研究了财政分权、企业寻租与地方政府补助之间的关系。研究发现:(1)总体上看,财政分权程度越高的地区,政府对企业的补助越少,而且企业寻租有助于其获得政府补助;(2)区分不同所有制企业后,财政分权程度越高的地区,政府对国有企业的补助越多,而对非国有企业的补助则越少,说明在政府补助方面存在所有制歧视,国有企业的预算软约束问题依然突出。因此,营造不同所有制经济公平竞争、共同发展的制度环境任重而道远。

A GROWING FAMILY

New development lender in Asia assists with regional infrastructure connectivityThe Asian Infrastructure Investment Bank（AIIB）announced on April 6 that it had admitted 13 new members,bringing its total approved membership to 70.The new AIIB members come from Asia,Africa,Europeand the Americas.