A new ureido-substituted amino acid,conopsamide A（1）,has been isolated from an ethanolic extract of the tubers of Gymnadenia conopsea.Its structure was elucidated by extensive spectroscopic analysis,and the absolute...A new ureido-substituted amino acid,conopsamide A（1）,has been isolated from an ethanolic extract of the tubers of Gymnadenia conopsea.Its structure was elucidated by extensive spectroscopic analysis,and the absolute configuration was assigned by Marfey＇s method.The new compound was evaluated for in vitro assay for HDACl（Histone Deacetylase 1） inhibitory activity.展开更多
基金Financial support from the National Natural Science Foundation of China (No. 81522050)Beijing outstanding talents cultivation fund (No. 2013D009008000002)the Natural Science Foundation of Qinghai Province (No. 2014-ZJ-923)
文摘A new ureido-substituted amino acid,conopsamide A（1）,has been isolated from an ethanolic extract of the tubers of Gymnadenia conopsea.Its structure was elucidated by extensive spectroscopic analysis,and the absolute configuration was assigned by Marfey＇s method.The new compound was evaluated for in vitro assay for HDACl（Histone Deacetylase 1） inhibitory activity.
