Objective To prospectively evaluate the efficacy of Removing Stasis and Reducing Heat Formula in accelerating calculus clearance and improving lower urinary tract symptoms of patients with proximal ureteral calculi af...Objective To prospectively evaluate the efficacy of Removing Stasis and Reducing Heat Formula in accelerating calculus clearance and improving lower urinary tract symptoms of patients with proximal ureteral calculi after ureteroscopic Ho:YAG laser lithotripsy. Methods A total of 138 patients with proximal ureteral calculi underwent ureteroscopic Ho:YAG laser lithotripsy by a single endocrinologist. Stone size varied from 10 to 15 mm. After operation, the patients were randomly divided into three groups: the control group(group A), tamsulosin group(group B), and Removing Stasis and Reducing Heat Formula group(group C). The treatment lasted for 4 weeks or until stone clearance. The primary and secondary outcomes of the three groups at follow-up were assessed. Results Of the 131 patients available for follow-up, 44 cases were in the group A, 45 in the group B, and 42 in the group C, respectively. The stone free rate at 2 weeks in the groups B and C were significantly higher than that in the group A(95.56%, 97.62% vs. 79.55%; all P<0.05). The ureteral colic rate and mean time of fragment expulsion were significantly reduced in the groups B(4.44% and 7.86±4.99 days) and C(2.43% and 6.76±4.37 days) compared with the group A(22.73% and 11.54±9.89 days, all P<0.05). On the day of double-J ureteric stent removal, the group C differed significantly from the group A in the total International Prostate Symptom Score, irritative subscore, obstructive subscore, and quality of life score(all P<0.05). Conclusion Removing Stasis and Reducing Heat Formula in the medical expulsive therapy might be an effective modality for patients with calculus in the proximal uretera after ureteroscopic Ho:YAG laser lithotripsy.展开更多
A stable wavelength operation Ho:YAG laser dual-pumped by two orthogonally polarized Tm:YLF lasers is reported. Under the cw operation mode, a laser output power of 24 W is measured. The corresponding opticaloptical c...A stable wavelength operation Ho:YAG laser dual-pumped by two orthogonally polarized Tm:YLF lasers is reported. Under the cw operation mode, a laser output power of 24 W is measured. The corresponding opticaloptical conversion efficiency is 44.75% and the slope efficiency is 50.12%. Under the Q-switched operation mode,the output maximum average power is 22.8 W at the re-frequency of 6 kHz. The corresponding optical-optical conversion efficiency and slope efficiency are 42.64% and 48.01%, respectively. The output central wavelength is 2090.73 nm, the linewidth is 0.40 nm, and the beam quality is M^2< 1.6. Moreover, the shift of the output central wavelength is less than 0.01 nm, and the linewidth shift is also less than 0.01 nm.展开更多
An actively mode-locked Ho: YAG laser pumped by a diode-pumped Tin-doped fiber laser is reported. For the cw operation, we obtain the maximum output power of 3.43 W with a central wavelength 2022.2nm at the maximum i...An actively mode-locked Ho: YAG laser pumped by a diode-pumped Tin-doped fiber laser is reported. For the cw operation, we obtain the maximum output power of 3.43 W with a central wavelength 2022.2nm at the maximum incident pump power of 11.4 W, corresponding to a slope efficiency of 34.5%. The beam quality factor M2 is 1.16, and the output beam is close to fundamental TEMoo. In the case of the CWML operation, a stable pulse train is generated with an average output power up to 3.41 W with a slope efficiency of 34.3% at the incident pump power of 11.4 W and a pulse duration of 294ps at a repetition rate of 81.92MHz. In addition, the maximum single pulse energy is 41.6nJ.展开更多
We present a Tm-doped fiber laser pumped Fabry-Perot etalons Ho:YAG laser based on a corner cube. A maximum single-longitudinal-mode and fundamental transverse mode output power of 478 m W at the wavelength of 2091.0...We present a Tm-doped fiber laser pumped Fabry-Perot etalons Ho:YAG laser based on a corner cube. A maximum single-longitudinal-mode and fundamental transverse mode output power of 478 m W at the wavelength of 2091.06 nm is achieved with a pump power of 16.3 W, corresponding to an optical-to-optical efficiency of 2.9% and a slope efficiency of 7.9%. The single-longitudinal-mode and fundamental transverse mode are less sensitive to the rotating of the corner cube. The results indicate the potential impact of a single-longitudinal-mode Ho: YA G laser with corner cube geometry to improve the anti-maladjustment stability.展开更多
A linearly polarized operation Ho: YAG laser at 2090.5 nm with a corner cube cavity is demonstrated. A polarizer with high reflectivity for the s-polarized light at the laser wavelength is employed to achieve a linea...A linearly polarized operation Ho: YAG laser at 2090.5 nm with a corner cube cavity is demonstrated. A polarizer with high reflectivity for the s-polarized light at the laser wavelength is employed to achieve a linearly polarized laser. In the same case of resonator length, the corner cube can be used to cut the volume of the Ho:YAG laser and to enhance the stability of the system. The maximum linearly polarized output power of 5.8 W is achieved at the absorbed pump power of 23.3 W, corresponding to a slope efficiency of 29.7%, and the optical-optical conversion efficiency is around 24.9%. The M2 factors of the 2.09μm laser are 2.4 and 1.2 along the horizontal and vertical directions, respectively.展开更多
We demonstrate a mid-IR ZnGeP2 (ZGP) optical parametric oscillator (OPO) pumped by a dual-end-pumped actively aeoasto-optie Q-switched Ho:YAG ceramic laser. The maximum average output power of 35 W is obtained at...We demonstrate a mid-IR ZnGeP2 (ZGP) optical parametric oscillator (OPO) pumped by a dual-end-pumped actively aeoasto-optie Q-switched Ho:YAG ceramic laser. The maximum average output power of 35 W is obtained at a pulse repetition frequency of 20 kHz from the Ho:YAG ceramic laser. Under the maximum incident pump power of Ho:YAG ceramic laser, the maximum output power of 14 W is obtained from the ZGP OPO, corresponding to the slope efficiency of 49.6% with respect to the incident pump power. The wavelength can be tuned from 3.5 μm to 4.2μm (signal), corresponding to 5.24.1 μm (idler). The beam quality M2 is less than 2.3 from the ZGP OPO.展开更多
We present a high-power Ho:YAG ceramic laser pumped at 1908nm. Using a dual-end-pumped structure, the maximum continuous-wave output power of 48 W is obtained, corresponding to a slope efficiency of 70.4% with respec...We present a high-power Ho:YAG ceramic laser pumped at 1908nm. Using a dual-end-pumped structure, the maximum continuous-wave output power of 48 W is obtained, corresponding to a slope efficiency of 70.4% with respect to the absorbed pump power. At actively Q-switched mode, the maximum average output power of 46 W and the minimum pulse width of 21 ns are achieved at a pulse repetition frequency of 20 kHz, corresponding to a peak power of approximately 109.5kW. In addition, the beam-quality M2 factor is found to be 1.4 at the maximum output power.展开更多
文摘Objective To prospectively evaluate the efficacy of Removing Stasis and Reducing Heat Formula in accelerating calculus clearance and improving lower urinary tract symptoms of patients with proximal ureteral calculi after ureteroscopic Ho:YAG laser lithotripsy. Methods A total of 138 patients with proximal ureteral calculi underwent ureteroscopic Ho:YAG laser lithotripsy by a single endocrinologist. Stone size varied from 10 to 15 mm. After operation, the patients were randomly divided into three groups: the control group(group A), tamsulosin group(group B), and Removing Stasis and Reducing Heat Formula group(group C). The treatment lasted for 4 weeks or until stone clearance. The primary and secondary outcomes of the three groups at follow-up were assessed. Results Of the 131 patients available for follow-up, 44 cases were in the group A, 45 in the group B, and 42 in the group C, respectively. The stone free rate at 2 weeks in the groups B and C were significantly higher than that in the group A(95.56%, 97.62% vs. 79.55%; all P<0.05). The ureteral colic rate and mean time of fragment expulsion were significantly reduced in the groups B(4.44% and 7.86±4.99 days) and C(2.43% and 6.76±4.37 days) compared with the group A(22.73% and 11.54±9.89 days, all P<0.05). On the day of double-J ureteric stent removal, the group C differed significantly from the group A in the total International Prostate Symptom Score, irritative subscore, obstructive subscore, and quality of life score(all P<0.05). Conclusion Removing Stasis and Reducing Heat Formula in the medical expulsive therapy might be an effective modality for patients with calculus in the proximal uretera after ureteroscopic Ho:YAG laser lithotripsy.
基金Supported by the Cooperation Foundation of Changchun Science and Technology Bureau under Grant No 17DY027the Foundation of Education Department of Jilin Province under Grant No JJKH20181105KJthe Foundation of Jilin Province Science and Technology Department under Grant No 20180101033JC
文摘A stable wavelength operation Ho:YAG laser dual-pumped by two orthogonally polarized Tm:YLF lasers is reported. Under the cw operation mode, a laser output power of 24 W is measured. The corresponding opticaloptical conversion efficiency is 44.75% and the slope efficiency is 50.12%. Under the Q-switched operation mode,the output maximum average power is 22.8 W at the re-frequency of 6 kHz. The corresponding optical-optical conversion efficiency and slope efficiency are 42.64% and 48.01%, respectively. The output central wavelength is 2090.73 nm, the linewidth is 0.40 nm, and the beam quality is M^2< 1.6. Moreover, the shift of the output central wavelength is less than 0.01 nm, and the linewidth shift is also less than 0.01 nm.
基金Supported by the National Natural Science Foundation of China under Grant Nos 61308009 and 61405047the China Postdoctoral Science Foundation Funded Project under Grant Nos 2013M540288 and 2015M570290+2 种基金the Fundamental Research Funds for the Central Universities Grant under Grant Nos HIT.NSRIF.2014044 and HIT.NSRIF.2015042the Science Fund for Outstanding Youths of Heilongjiang Province under Grant No JQ201310the Heilongjiang Postdoctoral Science Foundation Funded Project under Grant No LBH-Z14085
文摘An actively mode-locked Ho: YAG laser pumped by a diode-pumped Tin-doped fiber laser is reported. For the cw operation, we obtain the maximum output power of 3.43 W with a central wavelength 2022.2nm at the maximum incident pump power of 11.4 W, corresponding to a slope efficiency of 34.5%. The beam quality factor M2 is 1.16, and the output beam is close to fundamental TEMoo. In the case of the CWML operation, a stable pulse train is generated with an average output power up to 3.41 W with a slope efficiency of 34.3% at the incident pump power of 11.4 W and a pulse duration of 294ps at a repetition rate of 81.92MHz. In addition, the maximum single pulse energy is 41.6nJ.
基金Supported by the National Natural Science Foundation of China under Grant Nos 61308009 and 61405047the China Postdoctoral Science Foundation Funded Project under Grant No 2013M540288+2 种基金the Fundamental Research Funds for the Central Universities under Grant Nos HIT.NSRIF.2014044 and HIT.NSRIF.2015042the Science Fund for Outstanding Youths of Heilongjiang Province under Grant No JQ201310the Heilongjiang Postdoctoral Science Foundation Funded Project under Grant No LBH-Z14085
文摘We present a Tm-doped fiber laser pumped Fabry-Perot etalons Ho:YAG laser based on a corner cube. A maximum single-longitudinal-mode and fundamental transverse mode output power of 478 m W at the wavelength of 2091.06 nm is achieved with a pump power of 16.3 W, corresponding to an optical-to-optical efficiency of 2.9% and a slope efficiency of 7.9%. The single-longitudinal-mode and fundamental transverse mode are less sensitive to the rotating of the corner cube. The results indicate the potential impact of a single-longitudinal-mode Ho: YA G laser with corner cube geometry to improve the anti-maladjustment stability.
基金Supported by the National Natural Science Foundation of China under Grant Nos 61308009 and 61405047the China Postdoctoral Science Foundation Funded Project under Grant No 2013M540288+1 种基金the Fundamental Research Funds for the Central Universities under Grant Nos HIT.NSRIF.2014044 and HIT.NSRIF.2015042the Science Fund for Outstanding Youths of Heilongjiang Province under Grant No JQ201310
文摘A linearly polarized operation Ho: YAG laser at 2090.5 nm with a corner cube cavity is demonstrated. A polarizer with high reflectivity for the s-polarized light at the laser wavelength is employed to achieve a linearly polarized laser. In the same case of resonator length, the corner cube can be used to cut the volume of the Ho:YAG laser and to enhance the stability of the system. The maximum linearly polarized output power of 5.8 W is achieved at the absorbed pump power of 23.3 W, corresponding to a slope efficiency of 29.7%, and the optical-optical conversion efficiency is around 24.9%. The M2 factors of the 2.09μm laser are 2.4 and 1.2 along the horizontal and vertical directions, respectively.
基金Supported by the National Natural Science Foundation of China under Grant Nos 61308009,61405047 and 50990301the Fundamental Research Funds for the Central Universities under Grant Nos HIT.NSRIF.2014044 and HIT.NSRIF.2015042the Science Fund for Outstanding Youths of Heilongjiang Province under Grant No JQ201310
文摘We demonstrate a mid-IR ZnGeP2 (ZGP) optical parametric oscillator (OPO) pumped by a dual-end-pumped actively aeoasto-optie Q-switched Ho:YAG ceramic laser. The maximum average output power of 35 W is obtained at a pulse repetition frequency of 20 kHz from the Ho:YAG ceramic laser. Under the maximum incident pump power of Ho:YAG ceramic laser, the maximum output power of 14 W is obtained from the ZGP OPO, corresponding to the slope efficiency of 49.6% with respect to the incident pump power. The wavelength can be tuned from 3.5 μm to 4.2μm (signal), corresponding to 5.24.1 μm (idler). The beam quality M2 is less than 2.3 from the ZGP OPO.
基金Supported by the National Natural Science Foundation of China under Grant Nos 61308009,61405047 and 50990301the China Postdoctoral Science Foundation Funded Project under Grant No 2015T80339+1 种基金the Fundamental Research Funds for the Central Universities under Grant No HIT.NSRIF.2015042the Science Fund for Outstanding Youths of Heilongjiang Province under Grant No JQ201310
文摘We present a high-power Ho:YAG ceramic laser pumped at 1908nm. Using a dual-end-pumped structure, the maximum continuous-wave output power of 48 W is obtained, corresponding to a slope efficiency of 70.4% with respect to the absorbed pump power. At actively Q-switched mode, the maximum average output power of 46 W and the minimum pulse width of 21 ns are achieved at a pulse repetition frequency of 20 kHz, corresponding to a peak power of approximately 109.5kW. In addition, the beam-quality M2 factor is found to be 1.4 at the maximum output power.