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Fresh human amniotic membrane effectively promotes the repair of injured common peroneal nerve 被引量:5
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作者 Zhong-Yuan Zhang Jin Yang +5 位作者 Zhen-Hai Fan Da-Li Wang Yu-Ying Wang Tao Zhang Li-Mei Yu Chang-Yin Yu 《Neural Regeneration Research》 SCIE CAS CSCD 2019年第12期2199-2208,共10页
Suture and autologous nerve transplantation are the primary therapeutic measures for completely severed nerves. However, imbalances in the microenvironment and adhesion of surrounding tissues can affect the quality of... Suture and autologous nerve transplantation are the primary therapeutic measures for completely severed nerves. However, imbalances in the microenvironment and adhesion of surrounding tissues can affect the quality of nerve regeneration and repair. Previous studies have shown that human amniotic membrane can promote the healing of a variety of tissues. In this study, the right common peroneal nerve underwent a 5-mm transection in rats. Epineural nerve repair was performed using 10/0 non-absorbable surgical suture. The repair site was wrapped with a two-layer amniotic membrane with α-cyanoacrylate rapid medical adhesive after suture. Hindlimb motor function was assessed using footprint analysis. Conduction velocity of the common peroneal nerve was calculated by neural electrical stimulation. The retrograde axoplasmic transport of the common peroneal nerve was observed using fast blue BB salt retrograde fluorescent staining. Hematoxylin- eosin staining was used to detect the pathological changes of the common peroneal nerve sputum. The mRNA expression of axon regeneration-related neurotrophic factors and inhibitors was measured using real-time polymerase chain reaction. The results showed that the amniotic membrane significantly improved the function of the injured nerve;the toe spread function rapidly recovered, the nerve conduction velocity was restored, and the number of fast blue BB salt particles were increased in the spinal cord. The amniotic membrane also increased the recovery rate of the tibialis anterior muscle and improved the tissue structure of the muscle. Meanwhile, mRNA expression of nerve growth factor, growth associated protein-43, collapsin response mediator protein-2, and brain-derived neurotrophic factor recovered to near-normal levels, while Lingo-1 mRNA expression decreased significantly in spinal cord tissues. mRNA expression of glial-derived neurotrophic factor did not change significantly. Changes in mRNA levels were more significant in amniotic-membrane-wrapping-treated rats compared with model and nerve sutured rats. These results demonstrate that fresh amniotic membrane wrapping can promote the functional recovery of sutured common peroneal nerve via regulation of expression levels of neurotrophic factors and inhibitors associated with axonal regeneration. The study was approved by the Committee on Animal Research and Ethics at the Affiliate Hospital of Zunyi Medical University, China (approval No. 112) on December 1, 2017. 展开更多
关键词 nerve REGENERATION human amniotic membrane AXONAL Schwann cells α-cyanoacrylate rapid medical adhesive NEURAL suture TIBIAL anterior muscle neuronal growth factor common peroneal nerve injury NEURAL REGENERATION
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Electroacupuncture for Treatment of 12 Cases of Infantile Peroneal Nerve Injury
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作者 吕忠礼 陈志强 周永生 《Journal of Traditional Chinese Medicine》 SCIE CAS CSCD 2000年第2期130-131,共2页
Infantile peroneal nerve injury,also calledperoneal paralysis,is mostly caused by intraglutealinjection.Clinically,it is characterized by foot drop,strephenopodia,digital flexion,and high leg raisingwhile walking.The ... Infantile peroneal nerve injury,also calledperoneal paralysis,is mostly caused by intraglutealinjection.Clinically,it is characterized by foot drop,strephenopodia,digital flexion,and high leg raisingwhile walking.The authors have treated 12 cases ofperoneal nerve injury by electroacupuncture,withsatisfactory results reported as follows. 展开更多
关键词 Acupuncture Therapy ELECTROACUPUNCTURE CHILD Child Preschool Female Humans INFANT Male peroneal nerve peroneal Neuropathies
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Differential gene and protein expression between rat tibial nerve and common peroneal nerve during wallerian degeneration 被引量:4
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作者 Yao-Fa Lin Zheng Xie +2 位作者 Jun Zhou Gang Yin Hao-Dong Lin 《Neural Regeneration Research》 SCIE CAS CSCD 2019年第12期2183-2191,共9页
Wallerian degeneration and nerve regeneration after injury are complex processes involving many genes, proteins and cytokines. After different peripheral nerve injuries the regeneration rate can differ. Whether this i... Wallerian degeneration and nerve regeneration after injury are complex processes involving many genes, proteins and cytokines. After different peripheral nerve injuries the regeneration rate can differ. Whether this is caused by differential expression of genes and proteins during Wallerian degeneration remains unclear. The right tibial nerve and the common peroneal nerve of the same rat were exposed and completely cut through and then sutured in the same horizontal plane. On days 1, 7, 14, and 21 after surgery, 1–2 cm of nerve tissue distal to the suture site was dissected out from the tibial and common peroneal nerves. The differences in gene and protein expression during Wallerian degeneration of the injured nerves were then studied by RNA sequencing and proteomic techniques. In the tibial and common peroneal nerves, there were 1718, 1374, 1187, and 2195 differentially expressed genes, and 477, 447, 619, and 495 differentially expressed proteins on days 1, 7, 14, and 21 after surgery, respectively. Forty-seven pathways were activated during Wallerian degeneration. Three genes showing significant differential expression by RNA sequencing (Hoxd4, Lpcat4 and Tbx1) were assayed by real-time quantitative polymerase chain reaction. RNA sequencing and real-time quantitative polymerase chain reaction results were consistent. Our findings showed that expression of genes and proteins in injured tibial and the common peroneal nerves were significantly different during Wallerian degeneration at different time points. This suggests that the biological processes during Wallerian degeneration are different in different peripheral nerves after injury. The procedure was approved by the Animal Experimental Ethics Committee of the Second Military Medical University, China (approval No. CZ20160218) on February 18, 2016. 展开更多
关键词 nerve REGENERATION PERIPHERAL nerveS PERIPHERAL nerve injuries Wallerian degeneration TIBIAL nerve common peroneal nerve RNA sequencing proteomic real-time quantitative polymerase chain reaction neural REGENERATION
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Anatomical study of sciatic nerve and common peroneal nerve compression 被引量:1
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作者 Mingzhao Jia Qing Xia Jinmin Sun Qiang Zhou Weidong Wang 《Neural Regeneration Research》 SCIE CAS CSCD 2008年第6期621-624,共4页
BACKGROUND: Many diseases of the common peroneal nerve are a result of sciatic nerve injury. The present study addresses whether anatomical positioning of the sciatic nerve is responsible for these injuries. OBJECTIV... BACKGROUND: Many diseases of the common peroneal nerve are a result of sciatic nerve injury. The present study addresses whether anatomical positioning of the sciatic nerve is responsible for these injuries. OBJECTIVE: To analyze anatomical causes of sciatic nerve and common peroneal nerve injury by studying the relationship between the sciatic nerve and piriformis. DESIGN, TIME AND SETTING: Observe and measure repeatedly. The experiment was conducted in the Department of Anatomy, Tianjin Medical College between January and June 2005. MATERIALS: Fifty-two adult cadavers 33 males and 19 females, with a total of 104 hemispheres, and fixed with formaldehyde, were provided by Tianjin Medical College and Tianjin Medical University. METHODS: A posterior cut was made from the lumbosacral region to the upper leg, fully exposing the piriformis and path of the sciatic nerve. MAIN OUTCOME MEASURES: (1) Anatomical characteristics of the tibial nerve and common peroneal nerve. (2) According to different areas where the sciatic nerve crosses the piriformis, the study was divided into two types-normal and abnormal. Normal is considered to be when the sciatic nerve passes through the infrapiriform foramen. Remaining pathways are considered to be abnormal. (3) Observe the relationship between the suprapiriform foramen, infrapiriform foramen, as well as the superior and inferior space of piriformis. RESULTS: (1) The nerve tract inside the common peroneal nerve is smaller and thinner, with less connective tissue than the tibial nerve. When pathological changes or variations of the piriformis, or over-abduction of the hip joint, occur, injury to the common peroneal nerve often arises due to blockage and compression. (2) A total of 76 hemispheres (73.08%) were normal, 28 were abnormal (26.92%). The piriformis can be injured, and the sciatic nerve can become compressed, when the hip joint undergoes intorsion, extorsion, or abduction. (3) The structures between the infrapiriform and suprapiriform foramen are where "the first threshold" sciatic nerve projects. The structures between the infrapiriform and suprapiriform gap were "the second threshold". This became the concept of "double threshold". The reduced area caused by pathological changes of "double threshold" may block and compress the sciatic nerve. Because the common peroneal nerve lies on the anterolateral side of the sciatic nerve, injury to the common peroneal nerve is more serious. CONCLUSION: Anatomical characteristics of the common peroneal nerve, as well as variation of the sciatic nerve, piriformis, and the reduced "double threshold", are the main causes of sciatic nerve injury, and are especially common in peroneal nerve injury. 展开更多
关键词 sciatic nerve injury common peroneal nerve disease PIRIFORMIS
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Predictive Reliability of the Phoenix Sign for the Outcome of Common Fibular (Peroneal) Nerve Decompression Surgery
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作者 Stephen L. Barrett Adam Khan +3 位作者 Victoria Brown Erik Rosas Sequioa Du Casse Porscha Bailey 《Open Journal of Orthopedics》 2020年第9期234-240,共7页
<span style="font-family:Verdana;">A positive Phoenix sign occurs when a patient, with a suspected focal nerve entrapment of the Common Fibular (Peroneal) Nerve (CFN) at the level of the fibular neck, ... <span style="font-family:Verdana;">A positive Phoenix sign occurs when a patient, with a suspected focal nerve entrapment of the Common Fibular (Peroneal) Nerve (CFN) at the level of the fibular neck, demonstrates an improvement in dorsifexion after an ultrasound guided infiltration of a sub-anesthetic dose of lidocaine. Less than</span><span style="font-family:""> </span><span style="font-family:Verdana;">5 cc’s of 1% or 2% lidocaine is utilized and the effect is seen within minutes after the infiltration, but usually lasts only 10 minutes. This effect may be due to the vasodilatory action of lidocaine on the microcirculation in the area of infiltration. This nerve block has significant diagnostic utility as it is highly specific in the confirmation of true focal entrapment of the CFN, has high predictive value for a patient who may undergo surgical nerve decompression if they have demonstrated a positive Phoenix Sign, and may help in the surgical decision-making process in patients who have had a drop foot for many years but still may regain some motor function after decompression. In this retrospective review, 26 patients were tested, and 25</span><span style="font-family:""> </span><span style="font-family:""><span style="font-family:Verdana;">of this cohort demon</span><span style="font-family:Verdana;">strated a Positive Phoenix Sign (an increase in dorsiflexion strength of the</span><span style="font-family:Verdana;"> Extensor Hallucis Longus muscle (EHL)). One patient had no response to the </span><span style="font-family:Verdana;">peripheral nerve block. Of the 25 patients who demonstrated a positive</span><span style="font-family:Verdana;"> “Phoenix Sign” and underwent nerve decompression of the CFN, and 25 (100%) showed an increase in dorsiflexion strength of the EHL after nerve decom</span><span style="font-family:Verdana;">pression surgery of the CFN. The one patient in this cohort who did not</span><span style="font-family:Verdana;"> dem</span><span style="font-family:Verdana;">onstrate any improvement in dorsiflexion of the EHL after the nerve block</span><span style="font-family:Verdana;"> did not have any improvement after surgery. 展开更多
关键词 Peripheral nerve Block Drop Foot Ultrasound Guidance Common peroneal nerve Entrapment Common Fibular nerve Entrapment
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Hereditary Multiple Exostoses (HME) with Peroneal Nerve Compresion: A Case Report
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作者 Onarisa Ayu Muhammad Iqbal 《International Journal of Medical Physics, Clinical Engineering and Radiation Oncology》 2023年第2期51-57,共7页
Introduction: Hereditary multiple exostosis (HME) is a hereditary disorder characterized by multiple osteochondromas. Clinical symptoms can result from compression of adjacent structures such as peripheral nerves. In ... Introduction: Hereditary multiple exostosis (HME) is a hereditary disorder characterized by multiple osteochondromas. Clinical symptoms can result from compression of adjacent structures such as peripheral nerves. In Indonesia, HME with nerve compression cases have rarely reported. Presentation of Case: An eleven-year-old female with complaining of left knee joint pain and progressive masses in left lower leg since 6 years ago. This complains followed by numbness and difficulty to dorso flexion motion on left ankle joint since four months ago. Physical examination showed of the bony masses was detected at the left lateral upper third lower leg with measuring about six into eight centimeters. Range of motion of left ankle joint patient had difficult to dorso flexion. X-ray imaging viewed demonstrates multiple exostosis appearance involving distal femoral, proximal fibula, proximal tibia and distal fibula bone. MR Imaging revealed cartilage cap of head fibula is thin less 1.5 cm and the axially specimen showed peroneal nerve compression. The patient underwent left head fibula wide resection. Intraoperative findings peripheral nerve peroneal compression and was decompression. Medical rehabilitation for physiotherapy was advised. The results of the follow-up after 2 years, no pain feels and the patient was able to dorso flexion of left ankle joint and no additional bumps in other areas of the body. These lesions may arise from any bone which was pre-formed in the cartilage. Nerve compression syndromes are the neurological complex symptom caused by the mechanical or dynamic compression of a specific single segment. MRI was excellent demonstration of blood vessels compromise and represents choices with peripheral nerves structures and to measuring cartilage cap thickness for criterion of osteochondromas differentiation and exostotic grade. Complete resection was importance of the cartilaginous cap to prevent recurrence. The decompressing the peroneal nerve that pressured by the masses and vascular problems occured. Conclusion: Hereditary multiple exostosis is an inherited disorder characterized by multiple osteochondromas. It is important to monitor all cases of HME especially if the patient complains of pain or growth of an osteochondroma. The surgical excision, with complete resection of the cartilaginous cap of the tumor, is important in preventing recurrence. 展开更多
关键词 OSTEOCHONDROMA Hereditary Multiple Exostosis (HME) peroneal nerve Compression
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Natural history of sensory nerve recovery after cutaneous nerve injury following foot and ankle surgery 被引量:3
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作者 Lu Bai Yan-ni Han +2 位作者 Wen-tao Zhang Wei Huang Hong-lei Zhang 《Neural Regeneration Research》 SCIE CAS CSCD 2015年第1期99-103,共5页
Cutaneous nerve injury is the most common complication following foot and ankle surgery. However, clinical studies including long-term follow-up data after cutaneous nerve injury of the foot and ankle are lacking. In ... Cutaneous nerve injury is the most common complication following foot and ankle surgery. However, clinical studies including long-term follow-up data after cutaneous nerve injury of the foot and ankle are lacking. In the current retrospective study, we analyzed the clinical data of 279 patients who underwent foot and ankle surgery. Subjects who suffered from apparent paresthesia in the cutaneous sensory nerve area after surgery were included in the study. Pa- tients received oral vitamin B^2 and methylcobalamin. We examined final follow-up data of 17 patients, including seven with sural nerve injury, five with superficial peroneal nerve injury, and five with plantar medial cutaneous nerve injury. We assessed nerve sensory function using the Medical Research Council Scale. Follow-up immediately, at 6 weeks, 3, 6 and 9 months, and 1 year after surgery demonstrated that sensory function was gradually restored in most patients within 6 months. However, recovery was slow at 9 months. There was no significant difference in sensory function between 9 months and 1 year after surgery. Painful neuromas occurred in four patients at 9 months to 1 year. The results demonstrated that the recovery of sensory func- tion in patients with various cutaneous nerve injuries after foot and ankle surgery required at least 6 months. 展开更多
关键词 nerve regeneration natural history cutaneous nerve injury foot and ankle sural nerve superficial peroneal nerve medial plantar nerve neurosensory function neural regeneration
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Autologous transplantation with fewer fibers repairs large peripheral nerve defects 被引量:8
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作者 Jiu-xu Deng Dian-yin Zhang +7 位作者 Ming Li Jian Weng Yu-hui Kou Pei-xun Zhang Na Han Bo Chen Xiao-feng Yin Bao-guo Jiang 《Neural Regeneration Research》 SCIE CAS CSCD 2017年第12期2077-2083,共7页
Peripheral nerve injury is a serious disease and its repair is challenging. A cable-style autologous graft is the gold standard for repairing long peripheral nerve defects; however, ensuring that the minimum number of... Peripheral nerve injury is a serious disease and its repair is challenging. A cable-style autologous graft is the gold standard for repairing long peripheral nerve defects; however, ensuring that the minimum number of transplanted nerve attains maximum therapeutic effect remains poorly understood. In this study, a rat model of common peroneal nerve defect was established by resecting a 10-mm long right common peroneal nerve. Rats receiving transplantation of the common peroneal nerve in situ were designated as the in situ graft group. Ipsilateral sural nerves(10–30 mm long) were resected to establish the one sural nerve graft group, two sural nerves cable-style nerve graft group and three sural nerves cable-style nerve graft group. Each bundle of the peroneal nerve was 10 mm long. To reduce the barrier effect due to invasion by surrounding tissue and connective-tissue overgrowth between neural stumps, small gap sleeve suture was used in both proximal and distal terminals to allow repair of the injured common peroneal nerve. At three months postoperatively, recovery of nerve function and morphology was observed using osmium tetroxide staining and functional detection. The results showed that the number of regenerated nerve fibers, common peroneal nerve function index, motor nerve conduction velocity, recovery of myodynamia, and wet weight ratios of tibialis anterior muscle were not significantly different among the one sural nerve graft group, two sural nerves cable-style nerve graft group, and three sural nerves cable-style nerve graft group. These data suggest that the repair effect achieved using one sural nerve graft with a lower number of nerve fibers is the same as that achieved using the two sural nerves cable-style nerve graft and three sural nerves cable-style nerve graft. This indicates that according to the ‘multiple amplification' phenomenon, one small nerve graft can provide a good therapeutic effect for a large peripheral nerve defect. 展开更多
关键词 nerve regeneration peripheral nerve injury peripheral nerve defect autologous nerve graft functional recovery nerve conductionvelocity sural nerve common peroneal nerve sleeve bridging suture neural regeneration
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Proximal tibial and fibular physeal fracture causing popliteal artery injury and peroneal nerve injury: A case report and review of literature 被引量:2
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作者 Uday Guled Nirmal Raj Gopinathan Vijay G. Goni Arjun Rhh Rakesh John Prateek Behera 《Chinese Journal of Traumatology》 CAS CSCD 2015年第4期238-240,共3页
Either proximal tibial or tibial physeal injuries are rare. The combination of both is even rarer, let alone causes a vascular injury. Early intervention is the key for management. We hereby present an interesting cas... Either proximal tibial or tibial physeal injuries are rare. The combination of both is even rarer, let alone causes a vascular injury. Early intervention is the key for management. We hereby present an interesting case of simultaneous proximal tibiofibular physeal injury with popliteal arterial occlusion and common peroneal nerve injury. The present case is important in two aspects: firstly it reports a very rare occurrence of simultaneous proximal tibiofibular physeal injury associated with vascular insult and common peroneal nerve injury; secondly it highlights that with timely intervention excellent results can be achieved in paediatric patients. 展开更多
关键词 physeal injury peroneal nerve Popliteal artery Tibia fracture
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CHANGED CONTENTS OF MONOAMINES AND THEIR METABOLITES OF CEREBROSPINAL FLUID DURING INHIBITION OF DEFENCE PRESSOR RESPONSE BY INPUTS OF DEEP PERONEAL NERVE IN RABBITS 被引量:1
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作者 夏萤 张安中 +2 位作者 曹小定 唐琴梅 徐修容 《Chinese Science Bulletin》 SCIE EI CAS 1989年第13期1134-1139,共6页
It has been demonstrated that excitation of hypothalamic defence area (HDA) causes an increase in sympathetic activity of the cardiovascular system and changes of other functions, which may be related to the activitie... It has been demonstrated that excitation of hypothalamic defence area (HDA) causes an increase in sympathetic activity of the cardiovascular system and changes of other functions, which may be related to the activities of central monoamines; electroacupuncture applied to "Zusanli" or deep peroneal nerve stimulation (DPNS) can inhibit HDA stimulation-induced pressor, ventricular extrasystoles and other de- 展开更多
关键词 deep peroneal nerve DEFENCE reaction HYPOTHALAMUS
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RELATIONSHIP BETWEEN THE BRAIN MONO-AMINE NEUROTRANSMITTERS AND ENDOGE-NOUS OPIOID PEPTIDES DURING INHIBITION OF DEFENCE PRESSOR RESPONSE BY INPUTS OF DEEP PERONEAL NERVE IN RABBITS 被引量:1
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作者 夏萤 张安中 +2 位作者 曹小定 唐琴梅 徐修容 《Chinese Science Bulletin》 SCIE EI CAS 1989年第14期1221-1225,共5页
It has been reported that stimulation of hypothalamic defence area (HDA) led to the increased release of central NA and other monoamine neurotransmitters,
关键词 deep peroneal nerve DEFENCE reaction pressor endogenous opioid peptide MONOAMINE NEUROTRANSMITTER
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Acupuncture for 24 cases of peroneal nerve palsy 被引量:1
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作者 柏树祥 《World Journal of Acupuncture-Moxibustion》 2012年第3期55-56,共2页
Objective To explore the effective therapy for peroneal nerve palsy.Methods Twenty-four cases of peroneal nerve palsy took acupuncture treatment,with acupoints of Bāfēng(八风 EX-LE 10),Tàichōng(太冲 LR 3),... Objective To explore the effective therapy for peroneal nerve palsy.Methods Twenty-four cases of peroneal nerve palsy took acupuncture treatment,with acupoints of Bāfēng(八风 EX-LE 10),Tàichōng(太冲 LR 3),Yánglíngquán(阳陵泉 GB 34),Xuánzhōng(悬钟 GB 39) etc.,once a day,10 times as a course.Results Twenty-four cases were all cured after 1-4 courses.Conclusion Acupuncture for peroneal nerve palsy shows a significant therapeutic effect. 展开更多
关键词 peroneal nerve palsy acupuncture therapy foot drop
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Electrical Stimulation of Deep Peroneal Nerve Mimicking Acupuncture Inhibits the Pressor Response via Capsaicin-lnsensitive Afferents in Anesthetized Rats
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作者 孙霞 蓝倩倩 +1 位作者 蔡勇 虞燕琴 《Chinese Journal of Integrative Medicine》 SCIE CAS 2012年第2期130-136,共7页
Objective: To assess the inhibitory modulation of blood pressure by stimulation of the deep peroneal nerve (DPN) and to determine the involvement of nociceptive fibers in the modulation. Methods: All the animals w... Objective: To assess the inhibitory modulation of blood pressure by stimulation of the deep peroneal nerve (DPN) and to determine the involvement of nociceptive fibers in the modulation. Methods: All the animals were divided into six groups (A-F). The rats in groups A and B received no pretreatment. The rats in groups C and D received subcutaneous injection of capsaicin or control vehicle, respectively, near the DPN for 2 days. Those in groups E and F had the DPN exposed to capsaicin or control vehicle, respectively, for 20 min. Subsequently, pressor responses were induced by stimulation of paraventricular nucleus (PVN) either electrically (groups A and C-F) or chemically via injection of glutamate (group B). After two stable pressor responses (baseline), all groups were subject to 5-min DPN stimulation followed by PVN stimulation for 10 s. Arterial blood pressure, heart rate, and electrocardiogram were recorded. The pressor response was calculated as the difference in the mean arterial pressure (MAP) before and after PVN stimulation, and changes from baseline in pressor response after DPN stimulation were compared between the groups. Results: Increases of MAP of 22.88 + 2.18 mm Hg and 20.32 + 5.25 mm Hg were induced by electrical (group A) or chemical (group B) stimulation of the PVN, respectively. These pressor responses were inhibited by stimulation of the DPN, and the MAP was reduced to 12.00 _+ 2.10 mm Hg in group A (n=6, P〈0.01) and 7.00 + 2.85 mm Hg in group B (n=6, P〈0.01). Subcutaneous injection of capsaicin (125 mg/kg) near the DPN in group C (n=7) had no effect on the inhibitory effect of DPN stimulation compared with the group D (n=9), and neither did blockade of nociceptive fibers with capsaicin in group E (n=6) compared with group F (n=8). Conclusion: Stimulation of the DPN mimicking acupuncture has an inhibitory effect on the pressor response, and the effect is mediated by capsaicin-insensitive afferent fibers in the DPN. 展开更多
关键词 ACUPUNCTURE deep peroneal nerve hypothalamic paraventricular nucleus pressor response capsaicin
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芒针治疗腓总神经损伤经验拾零 被引量:1
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作者 郭娅露 周婷 +1 位作者 李伟 田梦卓 《中医临床研究》 2024年第3期132-134,共3页
腓总神经损伤在现代医学中属于下肢周围神经损伤疾病,占下肢神经损伤的50.9%,因其解剖位置表浅,故骨折、外伤、手术等均易致其损伤,在临床上多被忽视,常于患者出现症状后才被发觉。临床上尤以小腿及足运动功能和/或感觉功能异常为最明... 腓总神经损伤在现代医学中属于下肢周围神经损伤疾病,占下肢神经损伤的50.9%,因其解剖位置表浅,故骨折、外伤、手术等均易致其损伤,在临床上多被忽视,常于患者出现症状后才被发觉。临床上尤以小腿及足运动功能和/或感觉功能异常为最明显的症状。随着病程的进展,患者可能出现足下垂、足背伸不能、足外翻功能障碍等,严重影响患者的日常生活。腓总神经损伤属于中医学中“痿证”范畴,指以肢体筋脉弛缓,软弱无力,不能随意运动,或伴有肌肉萎缩为主症的病证。本病病变部位在筋脉肌肉,病变脏器涉及肺、脾(胃)、肝、肾,基本病机为津液、气血、精髓亏虚,不能濡养肌肉筋脉。病理性质分为虚证与实证,也可见虚实夹杂。针灸在补虚泻实方面具有独特优势,而芒针相对于普通毫针具有刺激性更强、针感透传更深的特点,以此增强针灸治疗的效果。导师周婷主任为广德张氏芒针第四代传人,全国第五批名老中医继承人,从业20余年,尤擅长运用芒针治疗神经系统相关疾病,并在临床取得了良好的疗效。文章通过介绍周婷主任医师运用芒针治疗腓总神经损伤的医案,总结周婷主任治疗该病的临床经验,期望为临床治疗腓总神经损伤提供新的思路。 展开更多
关键词 芒针 腓总神经损伤 经验
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恢刺法治疗腓总神经损伤踝背屈功能疗效观察 被引量:2
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作者 韩美美 段丽阳 +2 位作者 吕楠 尚清 石立业 《中国中西医结合儿科学》 2024年第1期62-65,共4页
目的 比较恢刺法与常规针刺法对腓总神经损伤的疗效差异。方法 采用回顾性队列研究方法,收集2018年3月至2022年10月河南省儿童医院康复科住院和门诊收治的腓总神经损伤患儿的临床资料,根据治疗方案不同分为恢刺组和常规针刺组,每组各收... 目的 比较恢刺法与常规针刺法对腓总神经损伤的疗效差异。方法 采用回顾性队列研究方法,收集2018年3月至2022年10月河南省儿童医院康复科住院和门诊收治的腓总神经损伤患儿的临床资料,根据治疗方案不同分为恢刺组和常规针刺组,每组各收集20例,共40例。两组均选择患侧下肢阳陵泉、足三里、三阴交、解溪、太冲等穴位,恢刺组在常规取穴基础上予以行针,常规针刺组在针刺得气后予以平补平泻,每次留针30 min。两组均每日1次,每周5次,4周(20次)为1个疗程,共治疗8周(2个疗程)后评定疗效。观察两组治疗效果及下肢运动功能评估、足背屈角度变化。结果 治疗后恢刺组总有效率为90.0%(18/20),显著高于常规针刺组60.0%(12/20),差异有统计学意义(P<0.05)。治疗后,恢刺组Fugl-Meyer运动功能评分及踝关节背屈活动度改善程度明显高于常规针刺组,差异有统计学意义(P<0.05)。结论 恢刺法在改善下肢运动功能和踝关节活动度方面治疗效果优于常规针刺法,值得临床推广应用。 展开更多
关键词 腓总神经损伤 针刺 恢刺 踝背屈
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带腓动脉穿支腓肠神经营养血管皮瓣在足背创面修复中的应用
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作者 张汉霖 康毅 +5 位作者 李亚岚 吴建科 李晓亮 马国续 高剑 黄永禄 《宁夏医学杂志》 CAS 2024年第2期125-127,共3页
目的探讨腓动脉穿支腓肠神经营养血管皮瓣修复足背创面的临床治疗效果。方法选择腓动脉穿支腓肠神经营养血管皮瓣修复足背创面缺损患者15例,男8例,女7例,年龄43~66岁,平均年龄(50.40±6.59)岁,创面均为足背缺损,缺损面积3 cm×5... 目的探讨腓动脉穿支腓肠神经营养血管皮瓣修复足背创面的临床治疗效果。方法选择腓动脉穿支腓肠神经营养血管皮瓣修复足背创面缺损患者15例,男8例,女7例,年龄43~66岁,平均年龄(50.40±6.59)岁,创面均为足背缺损,缺损面积3 cm×5 cm~6 cm×7 cm,所有患者均一期行清创VSD覆盖创面,二期行皮瓣覆盖创面的方法治疗,皮瓣的供区缝合张力小的选择直接缝合,对于缝合张力过高可能出现皮肤坏死的选取同侧大腿皮肤游离植皮修复。所有患者均采取上门、电话、微信拍照或者视频随访。定期随访患者患肢皮瓣外形、功能、供区及受区愈合情况和患者满意度。结果术后15例患者均获得随访,1例皮瓣出现远端部分表皮坏死,对创面加强换药后局部瘢痕愈合。随访13~22个月,平均(16.55±2.60)个月,在随访期间,患者的皮瓣呈现出正常的色泽、温度和毛细血管反应,未发现任何异常,皮瓣外形不臃肿,质地柔软,患足行走功能不受限。随访患者满意度评分在80分以上的为12例,评分在60~80分为2例,评分在60分以下为1例。结论腓动脉穿支腓肠神经营养血管皮瓣修复术,应用腓动脉在外踝后肌间隙穿出与腓肠神经营养血管吻合成网的优势,使皮瓣成活更可靠,血运更加理想,是修复足背侧创面缺损的理想方法。 展开更多
关键词 腓动脉穿支 腓肠神经营养血管皮瓣 软组织缺损
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超声引导下自体富血小板血浆注射治疗腓总神经卡压综合征—附1例报告
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作者 黄艺琪 覃兰惠 刘夕霞 《中国输血杂志》 CAS 2024年第9期1008-1012,共5页
目的观察1例超声引导下自体富血小板血浆(PRP)注射治疗腓总神经卡压综合征的临床疗效,为周围神经卡压性疾病的治疗提供借鉴。方法对1名腓总神经卡压综合征患者行超声引导下自体PRP神经水分离注射治疗,通过观察患者的症状、电生理及影像... 目的观察1例超声引导下自体富血小板血浆(PRP)注射治疗腓总神经卡压综合征的临床疗效,为周围神经卡压性疾病的治疗提供借鉴。方法对1名腓总神经卡压综合征患者行超声引导下自体PRP神经水分离注射治疗,通过观察患者的症状、电生理及影像学指标,评价PRP注射治疗对腓总神经卡压综合征的疗效。结果经系统注射治疗后,患者的症状、体征及肌电图指标均明显好转,且追踪3个月无明显不良反应。结论超声引导下PRP注射治疗改善了腓总神经卡压综合征中的神经功能障碍。 展开更多
关键词 超声引导 神经水分离 自体富血小板血浆 腓总神经卡压综合征
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水中运动疗法联合陆地物理疗法治疗62例腓总神经损伤的疗效分析 被引量:1
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作者 范慧 卓燕玲 +1 位作者 田德宽 孙莉 《中外医疗》 2024年第4期37-41,共5页
目的探讨水中运动疗法配合陆地物理疗法治疗腓总神经损伤的疗效。方法方便选取2021年2月-2023年2月北京和睦家康复医院收治的62例腓总神经损伤的患者为研究对象,按照随机数表法分为对照组和水疗组,每组31例。两组在神经营养药物治疗的同... 目的探讨水中运动疗法配合陆地物理疗法治疗腓总神经损伤的疗效。方法方便选取2021年2月-2023年2月北京和睦家康复医院收治的62例腓总神经损伤的患者为研究对象,按照随机数表法分为对照组和水疗组,每组31例。两组在神经营养药物治疗的同时,对照组给予传统的陆地物理疗法,水疗组通过水中运动疗法及陆地物理疗法相结合的方法治疗,共治疗8周。治疗前后用康复评定及神经电生理标准评定疗效。结果治疗后,水疗组踝关节背屈主动活动度为(7.28±3.06)°、10 m步行速度为(1.27±0.44)m/s,均优于对照组,差异有统计学意义(t=2.155、2.205,P均<0.05)。水疗组步长优于对照组,差异有统计学意义(P<0.05)。水疗组受损神经传导速度增加百分比与对照组比较,差异无统计学意义(P>0.05)。水疗组重用力运动单位电位募集频率百分比、受损神经复合肌肉动作电位波幅增加百分比,均优于对照组,差异有统计学意义(P均<0.05)。结论采用水中运动疗法联合陆地物理疗法治疗腓总神经的损伤的方法,比单独陆地物理疗法更有效。 展开更多
关键词 水中运动 腓总神经损伤 康复评定 电生理
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Presentation and management outcome of foot drop with tibialis posterior tendon transfer
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作者 Muhammad Saaiq 《World Journal of Orthopedics》 2024年第11期1047-1055,共9页
BACKGROUND Foot drop causes considerable disability.The ankle-dorsiflexion is either weak or lost completely.Additionally,the ankle eversion and toe extensions are also impaired.This results in a high steppage gait wh... BACKGROUND Foot drop causes considerable disability.The ankle-dorsiflexion is either weak or lost completely.Additionally,the ankle eversion and toe extensions are also impaired.This results in a high steppage gait while walking.Overall,the gait is awkward;there is greater energy consumption;increased proneness to sustain injury of the forefoot;and more frequent falling during walking.AIM To document the clinical and epidemiological profile of foot drop patients in our population and evaluate the outcome of tibialis posterior(TP)tendon transfer for restoring the lost dorsiflexion in foot drop.METHODS The study was carried out at the National Institute of Rehabilitation Medicine in Islamabad over a period of 7 years.It included patients of all sexes and ages who presented with foot drop and had no contraindications for the procedure of TP tendon transfer.Exclusion criteria were patients who had contraindications for the operation.For instance,paralyzed posterior leg compartment muscles,Achilles tendon contracture,stiff ankle or toes,unstable ankle joint,weak gastrocnemius and scarred skin spanning over the route of planned tendon transfer.Also,patients who had the foot drop as a result of disc prolapses or brain diseases were excluded.Convenience sampling technique was used.The circum-tibial route of TP tendon transfer was employed.RESULTS Out of 37 patients,26(70.27%)were males whereas 11(29.72%)were females.The mean age was 22.59±8.19 years.Among the underlying causes of foot drop,road traffic accidents constituted the most common cause,found among 20(54.05%)patients.The share of complications included wound infections in 3(8.10%)patients and hypertrophic scars in 2(5.40%)patients.At 1-year postoperative follow-up visits,the outcome was excellent in 8(21.62%),good in 20(54.05%)and moderate in 9(24.31%).CONCLUSION The majority of cases of foot drop resulted from road traffic accidents that directly involved the common peroneal nerve.TP tendon transfer through the circumtibial route was found to be an easily executed effective operation which restored good dorsiflexion of the ankle among the majority of patients. 展开更多
关键词 Foot drop Common peroneal nerve peroneal nerve palsy Tibialis posterior transfer Tibialis anterior Tendon transfer
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中药熏蒸联合穴位针刺疗法在脑出血后偏瘫患者中的应用效果
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作者 张淳 《中国伤残医学》 2024年第18期117-121,共5页
目的:探究中药熏蒸联合穴位针刺疗法在脑出血后偏瘫患者中的应用效果。方法:选取2022年1月-2024年1月天津市中医药研究院附属医院收治的97例脑出血后偏瘫患者为研究对象,采用随机数字表法分为研究组(n=49)及对照组(n=48)。对照组采用常... 目的:探究中药熏蒸联合穴位针刺疗法在脑出血后偏瘫患者中的应用效果。方法:选取2022年1月-2024年1月天津市中医药研究院附属医院收治的97例脑出血后偏瘫患者为研究对象,采用随机数字表法分为研究组(n=49)及对照组(n=48)。对照组采用常规干预,研究组在此基础上采用中药熏蒸联合穴位针刺干预。两组均干预1个月,比较两组患者的步行能力、肢体运动功能、神经传导速度及生活质量。结果:干预后,研究组的功能性步行量表评分、Fugl-Meyer运动功能评定量表评分、脑卒中专用生活质量量表评分均高于对照组,差异均有统计学意义(P<0.05)。干预后,胫神经运动神经传导速度(MCV)、腓总神经MCV均快于对照组,差异均有统计学意义(P<0.05)。结论:中药熏蒸联合穴位针刺干预可加快脑出血后偏瘫患者的患肢神经传导,提高其步行能力,改善其肢体运动能力及生活质量,具有较高的应用价值。 展开更多
关键词 脑出血 偏瘫 中药熏蒸 穴位针刺 胫神经 腓总神经
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