Objectives: Stroke is a major cause of morbidity and mortality worldwide. It is increasingly common from the sixth decade, but is particularly tragic when it occurs in young adults. There are limited studies of stroke...Objectives: Stroke is a major cause of morbidity and mortality worldwide. It is increasingly common from the sixth decade, but is particularly tragic when it occurs in young adults. There are limited studies of stroke in young adults in Nigeria. It is against this background that we embarked on this prospective hospital based study to determine the epidemiology, pattern and case fatality rate of stroke in young adults in Abakaliki Southeastern part of Nigeria. Patients and Method: The stroke patients between the ages of 18 - 50 years admitted to the medical wards of a tertiary health centre at Abakaliki Nigeria from 1st August 2012 to 30th April 2019 were consecutively recruited. They were followed up till discharge. Relevant data like biodata, and clinical features of the patients were extracted and analyzed. Results: A total of 983 (males—511, females—472) stroke cases were seen with 197 between 18 - 50 years. One hundred and fifty two (77%) did neuroimaging (mean age—40.7 years). Eighty-eight (57.9%) had Cerebral infarct (males—42, females—46) while 64 (42.1%) had Hemorrhagic stroke (males—35, females—29). For those that had hemorrhagic stroke, 11 (17.2%) were Subarachnoid hemorrhage (SAH) while 52 (82.8%) were Intracerebral hemorrhage (ICH). The identified risk factors range from hypertension, DM, dyslipidemia, alcoholism, cigarette smoking, HIV infection and chronic use of coffee drinks. Sixteen patients died during the admission with case fatality rate of 10.5%. Conclusion: Stroke is actually prevalent in young adults as 1 in every 5 stroke patients seen was a young adult. In addition to the traditional risk factors, HIV/AIDS and chronic use of coffee drinks were also noted as emerging risk factors. There is need for a continuous health education and strong campaign on primary stroke prevention. Also, there is need for training of more neurologists with interest in stroke management and establishing comprehensive stroke centers at national, regional and local levels in order to contend adequately with the rising burden of stoke in young adults.展开更多
目的:探讨索菲亚(SOFIA)远端通路导管抽吸取栓对急性缺血性卒中(cute ischemic stroke,AIS)患者血管再通及预后的影响。方法:回顾性选取2021年5月至2023年5月,沧州中西医结合医院就诊的166例AIS患者的临床资料,根据治疗方式分为抽吸组(6...目的:探讨索菲亚(SOFIA)远端通路导管抽吸取栓对急性缺血性卒中(cute ischemic stroke,AIS)患者血管再通及预后的影响。方法:回顾性选取2021年5月至2023年5月,沧州中西医结合医院就诊的166例AIS患者的临床资料,根据治疗方式分为抽吸组(64例)和支架组(102例),抽吸组采用SOFIA远端通路导管抽吸取栓治疗,支架组采用支架取栓治疗。比较两组患者再通成功率、一次成功再通率及穿刺到再通时间,术前和术后24h、7d美国国立卫生研究院卒中量表(national institute of health stroke scale,NIHSS)评分,术后3个月内并发症发生及预后情况。结果:两组比较,抽吸组一次成功再通率更高,穿刺到再通时间更短(P<0.05)。两组NIHSS评分的组间、交互比较,差异无统计学意义(P>0.05),时间比较(P<0.05)。抽吸组并发症发生率更低(P<0.05)。术后两组神经功能良好率和死亡率比较,差异无统计学意义(P>0.05)。结论:与支架取栓治疗相比,SOFIA远端通路导管抽吸取栓治疗AIS,可以提高一次成功再通率,缩短穿刺到再通时间,降低并发症发生率。展开更多
目的:对中国脑卒中病人营养风险的检出率进行系统评价与Meta分析。方法:计算机检索中国知网(CNKI)、维普数据库(VIP)、万方数据库(WanFang Database)、中国生物医学文献数据库(CBM)、PubMed、EMbase、Web of Science,收集从建库至2023年...目的:对中国脑卒中病人营养风险的检出率进行系统评价与Meta分析。方法:计算机检索中国知网(CNKI)、维普数据库(VIP)、万方数据库(WanFang Database)、中国生物医学文献数据库(CBM)、PubMed、EMbase、Web of Science,收集从建库至2023年4月30日关于中国脑卒中病人营养风险检出率的横断面研究。由2名研究者独立筛选文献、提取资料并评价纳入研究的偏倚风险,采用Stata 15.1软件进行Meta分析。结果:共纳入35项横断面研究,涉及9 616例脑卒中病人,其中3 975例存在营养风险,中国脑卒中病人营养风险总检出率为42.5%[95%CI(37.7%,47.4%)],亚组分析结果显示,男性和女性脑卒中病人营养风险检出率分别为50.0%、53.2%;60岁以下、60岁及以上脑卒中病人营养风险检出率分别为27.4%、47.7%;就脑卒中类型而言,缺血性脑卒中和出血性脑卒中病人营养风险检出率分别为50.1%、52.1%;首次发生脑卒中病人营养风险检出率(45.1%)低于有脑卒中病史病人(57.2%);合并吞咽困难脑卒中病人营养风险检出率(60.5%)高于未合并吞咽困难的脑卒中病人(34.9%);使用营养风险筛查2002、微型营养评估表、微型营养评价精法及营养不良通用筛查工具检测出脑卒中病人营养风险发生率分别为45.3%、23.3%、41.3%、42.3%。结论:我国脑卒中病人营养风险的检出率较高,不同亚组间脑卒中病人营养风险检出率存在差异。展开更多
目的分析血小板相关指标与急性缺血性卒中后抑郁(post-stroke depression,PSD)的关系。方法选取2021年9月至2022年5月在华北理工大学附属唐山市工人医院治疗的急性缺血性卒中病人235例,记录其一般临床资料,根据17项汉密顿抑郁量表(Hamil...目的分析血小板相关指标与急性缺血性卒中后抑郁(post-stroke depression,PSD)的关系。方法选取2021年9月至2022年5月在华北理工大学附属唐山市工人医院治疗的急性缺血性卒中病人235例,记录其一般临床资料,根据17项汉密顿抑郁量表(Hamilton depression rating scale,17 item,HAMD-17)评分将病人分为PSD组和非PSD组;测定各组病人血小板相关指标(血小板计数、血小板平均体积、血小板比容、血小板分布宽度);使用美国国立卫生院卒中量表(national institute of health stroke scale,NIHSS)、日常生活活动能力量表(activity of daily living,ADL)分别评估病人神经功能缺损情况和日常生活能力;采用多因素二元logistic回归模型分析与PSD相关的独立危险因素。结果研究共纳入缺血性脑卒中病人235例,PSD组病人85例,非PSD组病人150例。PSD组身体质量指数、NIHSS评分高于非PSD组,PSD组ADL评分低于非PSD组(P<0.05)。两组血小板计数和平均血小板体积分级分布上均差异有统计学差意义(P<0.05);PSD组血小板计数≤183×10^(9)/L、(>183~<257)×10^(9)/L、≥257×10^(9)/L分别有11例(12.9%)、47例(55.3%)、27例(31.8%),非PSD组分别有47例(31.3%)、72例(48.0%)、31例(20.7%)。多因素二元logistic回归分析结果显示,较高水平血小板计数、身体质量指数及NIHSS评分是PSD的独立危险因素(P<0.05)。结论较高水平的血小板计数是PSD发生的独立危险因素。展开更多
文摘Objectives: Stroke is a major cause of morbidity and mortality worldwide. It is increasingly common from the sixth decade, but is particularly tragic when it occurs in young adults. There are limited studies of stroke in young adults in Nigeria. It is against this background that we embarked on this prospective hospital based study to determine the epidemiology, pattern and case fatality rate of stroke in young adults in Abakaliki Southeastern part of Nigeria. Patients and Method: The stroke patients between the ages of 18 - 50 years admitted to the medical wards of a tertiary health centre at Abakaliki Nigeria from 1st August 2012 to 30th April 2019 were consecutively recruited. They were followed up till discharge. Relevant data like biodata, and clinical features of the patients were extracted and analyzed. Results: A total of 983 (males—511, females—472) stroke cases were seen with 197 between 18 - 50 years. One hundred and fifty two (77%) did neuroimaging (mean age—40.7 years). Eighty-eight (57.9%) had Cerebral infarct (males—42, females—46) while 64 (42.1%) had Hemorrhagic stroke (males—35, females—29). For those that had hemorrhagic stroke, 11 (17.2%) were Subarachnoid hemorrhage (SAH) while 52 (82.8%) were Intracerebral hemorrhage (ICH). The identified risk factors range from hypertension, DM, dyslipidemia, alcoholism, cigarette smoking, HIV infection and chronic use of coffee drinks. Sixteen patients died during the admission with case fatality rate of 10.5%. Conclusion: Stroke is actually prevalent in young adults as 1 in every 5 stroke patients seen was a young adult. In addition to the traditional risk factors, HIV/AIDS and chronic use of coffee drinks were also noted as emerging risk factors. There is need for a continuous health education and strong campaign on primary stroke prevention. Also, there is need for training of more neurologists with interest in stroke management and establishing comprehensive stroke centers at national, regional and local levels in order to contend adequately with the rising burden of stoke in young adults.
文摘目的:探讨索菲亚(SOFIA)远端通路导管抽吸取栓对急性缺血性卒中(cute ischemic stroke,AIS)患者血管再通及预后的影响。方法:回顾性选取2021年5月至2023年5月,沧州中西医结合医院就诊的166例AIS患者的临床资料,根据治疗方式分为抽吸组(64例)和支架组(102例),抽吸组采用SOFIA远端通路导管抽吸取栓治疗,支架组采用支架取栓治疗。比较两组患者再通成功率、一次成功再通率及穿刺到再通时间,术前和术后24h、7d美国国立卫生研究院卒中量表(national institute of health stroke scale,NIHSS)评分,术后3个月内并发症发生及预后情况。结果:两组比较,抽吸组一次成功再通率更高,穿刺到再通时间更短(P<0.05)。两组NIHSS评分的组间、交互比较,差异无统计学意义(P>0.05),时间比较(P<0.05)。抽吸组并发症发生率更低(P<0.05)。术后两组神经功能良好率和死亡率比较,差异无统计学意义(P>0.05)。结论:与支架取栓治疗相比,SOFIA远端通路导管抽吸取栓治疗AIS,可以提高一次成功再通率,缩短穿刺到再通时间,降低并发症发生率。
文摘目的分析血小板相关指标与急性缺血性卒中后抑郁(post-stroke depression,PSD)的关系。方法选取2021年9月至2022年5月在华北理工大学附属唐山市工人医院治疗的急性缺血性卒中病人235例,记录其一般临床资料,根据17项汉密顿抑郁量表(Hamilton depression rating scale,17 item,HAMD-17)评分将病人分为PSD组和非PSD组;测定各组病人血小板相关指标(血小板计数、血小板平均体积、血小板比容、血小板分布宽度);使用美国国立卫生院卒中量表(national institute of health stroke scale,NIHSS)、日常生活活动能力量表(activity of daily living,ADL)分别评估病人神经功能缺损情况和日常生活能力;采用多因素二元logistic回归模型分析与PSD相关的独立危险因素。结果研究共纳入缺血性脑卒中病人235例,PSD组病人85例,非PSD组病人150例。PSD组身体质量指数、NIHSS评分高于非PSD组,PSD组ADL评分低于非PSD组(P<0.05)。两组血小板计数和平均血小板体积分级分布上均差异有统计学差意义(P<0.05);PSD组血小板计数≤183×10^(9)/L、(>183~<257)×10^(9)/L、≥257×10^(9)/L分别有11例(12.9%)、47例(55.3%)、27例(31.8%),非PSD组分别有47例(31.3%)、72例(48.0%)、31例(20.7%)。多因素二元logistic回归分析结果显示,较高水平血小板计数、身体质量指数及NIHSS评分是PSD的独立危险因素(P<0.05)。结论较高水平的血小板计数是PSD发生的独立危险因素。
