Background: Brucellosis is a zoonotic endemic disease, the main source of infection is infected cattle, sheep, pigs and their products. In recent years, the global incidence of brucellosis spondylitis has increased ye...Background: Brucellosis is a zoonotic endemic disease, the main source of infection is infected cattle, sheep, pigs and their products. In recent years, the global incidence of brucellosis spondylitis has increased year by year, and it has spread from pastoral areas to semi-agricultural and semi-pastoral areas, agricultural areas and cities. It has changed from a mainly occupational disease to a mainly food-borne disease, and it is also a zoonotic specific spinal infectious disease that WHO and governments around the world pay great attention to. Due to the low cure rate and high recurrence rate of traditional drug therapy regimen. Therefore, to carry out epidemiological investigation and Related research on clinical drug therapy of brucellosis spondylitis has practical significance for improving diagnosis rate, cure rate and reducing recurrence rate. Objective: To analyze the epidemiological characteristics of Brucellosis spondylitis and explore the choice of drugs and the best drug treatment plan, so as to provide scientific basis for improving the prevention and control of the disease and treatment effect. Methods: Clinical epidemiodogical materials were collected from 113 patients with brucellar spondylitis. All these patients were divided into 5 different groups according to 5 kinds of drugs adopted respectively, and then the patients were given different course of treatment. Results: In the 113 patients, brucellar spondylitis morbility of female patients were higher than that of male ones, and the morbility of Bashang were higher than that of Baxia. These patients were infected mainly through browsing and breeding beasts. Lumbars were the major focus of infection. It was very comnlon that two adjacent lumbars were involved in concurrently. L4 was the most common infection location and its demolishment was most serious. The curative effect of group treated with doxycycline was better than that of group treated without doxycycline. If the course of treatment Was increased, the curative effect Was not increased obviously. Conclusions: There are characteristic features in clinical epidemiology of brucell spondylitis. Doxycycline + Rifampicin + Sulfamethoxazole was used as the preferred antibiotic. Using antibiotics adequately and jointly by two courses of treatment for a long time is the most reasonable way to treat the disease and prevent the disease from recurrence.展开更多
Objective： To observe the relationship between treatment course and therapeutic effect of acupuncture on female obesity in different types. Methods： The 83 cases of obesity were divided into two groups： abdominal o...Objective： To observe the relationship between treatment course and therapeutic effect of acupuncture on female obesity in different types. Methods： The 83 cases of obesity were divided into two groups： abdominal obesity group （AO, 31 cases） and symmetrical obesity group （SO, 52 cases）. All of them were treated by acupuncture for 3 months, 1 month as one course. Results： In Group AO, after one month of treatment, body mass index （BMI）, waist circumference （WC） and skin fat thickness （SFT） in the upper limbs （A）, trunk （B） and abdomen （at locations C and D） were very significantly reduced （P〈0.01）; After 2 months of treatment, BMI, WC and SFT at C were also very significantly reduced （P〈0.01）, SFT in A and at D was significantly reduced （P〈0.05）, but no significant SFT difference was found in B （/9〉0.05）; And after 3 months of treatment, no difference was found in any indices. In Group SO, all the indices including BMI, WC and SFT in A, B, C and D were reduced in the successive 3 months of treatment （P〈0.01）. Conclusions： The therapeutic effect of acupuncture on abdominal obesity was gradually lessened with the prolonging of treatment course, even without further advance after reaching the normal body weight range. But for symmetrical obesity, the effect was gradually advanced to reach the normal range. That their body weight in a normal range will be kept stable without further reduction remains to be studied further.展开更多
AIM: This study shares Asian clinical experiences of carcinoid tumors that originated in the upper gastrointestinal tract.METHODS: From May 1987 to June 2002, we had found only 13 cases of histologically confirmed car...AIM: This study shares Asian clinical experiences of carcinoid tumors that originated in the upper gastrointestinal tract.METHODS: From May 1987 to June 2002, we had found only 13 cases of histologically confirmed carcinoid tumors in the upper gastrointestinal tract by endoscopic examinations. There were eight males and five females.The mean age was 53.16±20.51 years that ranged from 26 to 82 years. Each of their clinical presentations,locations, tumor morphology, and size and the treatment outcome were analyzed and discussed.RESULTS: One patient had a polypoid lesion at the lower esophagus, nine were stomach lesions and three located at the duodenum. All patients with polypoid and submucosal tumor types were of small size (＜1.7 cm) and all patients survived after simple excision or polypectomy.Four of the five patients in tumor mass forms died and the tumors were more than 2.0 cm in size.CONCLUSION: Carcinoid tumors rarely originated from the upper gastrointestinal tract and are usually found accidentally after endoscopic study. Bigger size (more than 2 cm) tumor masses may indicate a more severe disease and poor prognosis.展开更多
Objective:To summarize the influence patterns of related time factors on acupuncture effectiveness in different disease model rats/mice,and to provide reference for acupuncture clinical practice.Methods:Retrieved the ...Objective:To summarize the influence patterns of related time factors on acupuncture effectiveness in different disease model rats/mice,and to provide reference for acupuncture clinical practice.Methods:Retrieved the relevant literatures on time-effect experimental studies of acupuncture in rats/mice in the recent 10 years.The correlations between the key time factors(such as different intervention timings of acupuncture,acupuncture moments,operation durations,needle-retaining times,intervals and treatment courses)and the acupuncture effect were analyzed and summarized.Results:From the mainstream perspective of quantification,the earlier the acupuncture intervention,the better.The proper time to implement acupuncture varied depending on disease models and points.The best operation time varied widely between different diseases.The most frequently needle-retaining time was 20-30 min.The frequency of acupuncture was usually 1 time/day;the length of the treatment course was determined according to practitioners'experience.Conclusion:Throughout the time-effect studies of acupuncture intervention in experimental rats/mice,conclusions are inconsistent,especially the lack of quantitative research on acupuncture operation time,acupuncture frequency,acupuncture treatment duration,and optimal stimulation amount.Future research should explore and determine the best time-quantity parameters that affect the effectiveness of acupuncture intervention,which is the key and goal of the acupuncture time-effect research.Independent intervention-time experiments throughout the entire course of a single disease(dominant disease)need to be done to guide clinical and disciplinary development.展开更多
文摘Background: Brucellosis is a zoonotic endemic disease, the main source of infection is infected cattle, sheep, pigs and their products. In recent years, the global incidence of brucellosis spondylitis has increased year by year, and it has spread from pastoral areas to semi-agricultural and semi-pastoral areas, agricultural areas and cities. It has changed from a mainly occupational disease to a mainly food-borne disease, and it is also a zoonotic specific spinal infectious disease that WHO and governments around the world pay great attention to. Due to the low cure rate and high recurrence rate of traditional drug therapy regimen. Therefore, to carry out epidemiological investigation and Related research on clinical drug therapy of brucellosis spondylitis has practical significance for improving diagnosis rate, cure rate and reducing recurrence rate. Objective: To analyze the epidemiological characteristics of Brucellosis spondylitis and explore the choice of drugs and the best drug treatment plan, so as to provide scientific basis for improving the prevention and control of the disease and treatment effect. Methods: Clinical epidemiodogical materials were collected from 113 patients with brucellar spondylitis. All these patients were divided into 5 different groups according to 5 kinds of drugs adopted respectively, and then the patients were given different course of treatment. Results: In the 113 patients, brucellar spondylitis morbility of female patients were higher than that of male ones, and the morbility of Bashang were higher than that of Baxia. These patients were infected mainly through browsing and breeding beasts. Lumbars were the major focus of infection. It was very comnlon that two adjacent lumbars were involved in concurrently. L4 was the most common infection location and its demolishment was most serious. The curative effect of group treated with doxycycline was better than that of group treated without doxycycline. If the course of treatment Was increased, the curative effect Was not increased obviously. Conclusions: There are characteristic features in clinical epidemiology of brucell spondylitis. Doxycycline + Rifampicin + Sulfamethoxazole was used as the preferred antibiotic. Using antibiotics adequately and jointly by two courses of treatment for a long time is the most reasonable way to treat the disease and prevent the disease from recurrence.
文摘Objective： To observe the relationship between treatment course and therapeutic effect of acupuncture on female obesity in different types. Methods： The 83 cases of obesity were divided into two groups： abdominal obesity group （AO, 31 cases） and symmetrical obesity group （SO, 52 cases）. All of them were treated by acupuncture for 3 months, 1 month as one course. Results： In Group AO, after one month of treatment, body mass index （BMI）, waist circumference （WC） and skin fat thickness （SFT） in the upper limbs （A）, trunk （B） and abdomen （at locations C and D） were very significantly reduced （P〈0.01）; After 2 months of treatment, BMI, WC and SFT at C were also very significantly reduced （P〈0.01）, SFT in A and at D was significantly reduced （P〈0.05）, but no significant SFT difference was found in B （/9〉0.05）; And after 3 months of treatment, no difference was found in any indices. In Group SO, all the indices including BMI, WC and SFT in A, B, C and D were reduced in the successive 3 months of treatment （P〈0.01）. Conclusions： The therapeutic effect of acupuncture on abdominal obesity was gradually lessened with the prolonging of treatment course, even without further advance after reaching the normal body weight range. But for symmetrical obesity, the effect was gradually advanced to reach the normal range. That their body weight in a normal range will be kept stable without further reduction remains to be studied further.
文摘AIM: This study shares Asian clinical experiences of carcinoid tumors that originated in the upper gastrointestinal tract.METHODS: From May 1987 to June 2002, we had found only 13 cases of histologically confirmed carcinoid tumors in the upper gastrointestinal tract by endoscopic examinations. There were eight males and five females.The mean age was 53.16±20.51 years that ranged from 26 to 82 years. Each of their clinical presentations,locations, tumor morphology, and size and the treatment outcome were analyzed and discussed.RESULTS: One patient had a polypoid lesion at the lower esophagus, nine were stomach lesions and three located at the duodenum. All patients with polypoid and submucosal tumor types were of small size (＜1.7 cm) and all patients survived after simple excision or polypectomy.Four of the five patients in tumor mass forms died and the tumors were more than 2.0 cm in size.CONCLUSION: Carcinoid tumors rarely originated from the upper gastrointestinal tract and are usually found accidentally after endoscopic study. Bigger size (more than 2 cm) tumor masses may indicate a more severe disease and poor prognosis.
文摘Objective:To summarize the influence patterns of related time factors on acupuncture effectiveness in different disease model rats/mice,and to provide reference for acupuncture clinical practice.Methods:Retrieved the relevant literatures on time-effect experimental studies of acupuncture in rats/mice in the recent 10 years.The correlations between the key time factors(such as different intervention timings of acupuncture,acupuncture moments,operation durations,needle-retaining times,intervals and treatment courses)and the acupuncture effect were analyzed and summarized.Results:From the mainstream perspective of quantification,the earlier the acupuncture intervention,the better.The proper time to implement acupuncture varied depending on disease models and points.The best operation time varied widely between different diseases.The most frequently needle-retaining time was 20-30 min.The frequency of acupuncture was usually 1 time/day;the length of the treatment course was determined according to practitioners'experience.Conclusion:Throughout the time-effect studies of acupuncture intervention in experimental rats/mice,conclusions are inconsistent,especially the lack of quantitative research on acupuncture operation time,acupuncture frequency,acupuncture treatment duration,and optimal stimulation amount.Future research should explore and determine the best time-quantity parameters that affect the effectiveness of acupuncture intervention,which is the key and goal of the acupuncture time-effect research.Independent intervention-time experiments throughout the entire course of a single disease(dominant disease)need to be done to guide clinical and disciplinary development.
