Objective:To observe the effects of acupoint thread-embedding therapy on serum apelin and glucagon-like peptide-1(GLP-1)in type 2 diabetes mellitus patients with obesity due to dampness-heat encumbering spleen.Methods...Objective:To observe the effects of acupoint thread-embedding therapy on serum apelin and glucagon-like peptide-1(GLP-1)in type 2 diabetes mellitus patients with obesity due to dampness-heat encumbering spleen.Methods:Sixty-six patients were randomly divided into a control group and an observation group according to the random number table method,with 33 cases in each group.Patients in the control group were treated with exenatide and metformin,while patients in the observation group were treated with additional acupoint thread-embedding.After 12-week treatment,the obesity-related indicators,including body mass index(BMI),waist circumference and body fat rate,the glycometabolism indicators,including fasting blood glucose,2 h postprandial blood glucose and glycosylated hemoglobin,and the lipid metabolism indicators,including total cholesterol(TC),triglyceride(TG)and low-density lipoprotein cholesterol(LDL-C),as well as serum apelin and GLP-1 levels were observed in patients of the two groups.Results:After treatment,the BMI,waist circumference and body fat rate of patients in the two groups were all reduced(all P<0.05),and were lower in the observation group than in the control group(all P<0.05);the fasting blood glucose,2 h postprandial blood glucose and glycosylated hemoglobin levels of patients in both groups were all decreased(all P<0.05),and were significantly lower in the observation group than in the control group(all P<0.05);the TC level was decreased(P<0.05),while the TG and LDL-C levels did not change significantly in the control group(both P>0.05);the TC,TG and LDL-C levels were all significantly reduced in the observation group(all P<0.05),lower than those in the control group(all P<0.05);the serum apelin level was decreased(P<0.05)and the serum GLP-1 level was increased(P<0.05)in the observation group,statistically different from those in the control group(both P<0.05).Conclusion:Combined with the conventional medication,acupoint thread-embedding therapy can significantly improve the obesity-related indicators,glycometabolism and lipid metabolism in type 2 diabetes mellitus patients with obesity due to dampness-heat encumbering spleen.This may be achieved by regulating the serum apelin and GLP-1 levels.展开更多
Objective:To investigate the effect of acupoint catgut-embedding therapy on non-alcoholic fatty liver disease(NAFLD).Methods:Twenty-three participants were subjected to acupoint catgut-embedding therapy for 3 sessions...Objective:To investigate the effect of acupoint catgut-embedding therapy on non-alcoholic fatty liver disease(NAFLD).Methods:Twenty-three participants were subjected to acupoint catgut-embedding therapy for 3 sessions.The second session was performed one month after the first session and the third session two months after the second session.Three months after the third session of catgut-embedding therapy,the patients were subjected to fibroscan analysis.A total of 20 acupoints were selected in three sessions.Same acupoints were selected for all the patients at the same session but different points were selected at different sessions.Results:Of the 23 participants,5 cases showed significant improvement and 8 cases showed moderate improvement as the steatosis stage was reduced by 1 or 2 degrees.The whole group showed significant improvements in terms of patient score,fat percentage,NAFLD steatosis stage,weight loss and abdominal circumference reduction after acupoint catgut-embedding therapy(all P<0.05).Conclusion:The acupoint catgut-embedding therapy can significantly improve the important factors in patients with NAFLD.展开更多
目的基于磁共振成像观察穴位埋线对单纯性肥胖患者局部经穴(天枢、脾俞、丰隆)刺激效应的时效特点。方法应用T2-mapping技术采集15例单纯性肥胖患者左侧天枢、脾俞、丰隆穴埋线前后不同时间段T2WI压脂及T2-mapping 8回波序列图像,传入...目的基于磁共振成像观察穴位埋线对单纯性肥胖患者局部经穴(天枢、脾俞、丰隆)刺激效应的时效特点。方法应用T2-mapping技术采集15例单纯性肥胖患者左侧天枢、脾俞、丰隆穴埋线前后不同时间段T2WI压脂及T2-mapping 8回波序列图像,传入后处理工作站生成伪彩图,获取信号最强的连续3个层面感兴趣区(region of interest,ROI)的T2值均数,分析天枢、脾俞、丰隆穴局部T2WI压脂序列图像的信号影强弱和T2值随时间变化的特点。结果天枢穴埋线后1、4 d ROI的T2值均较埋线前显著升高(P<0.05),均可见不同高信号影;埋线后1、2、3、4、5周ROI的T2值较埋线后4d显著下降(P<0.05),各时间段信号影接近埋线前。脾俞穴埋线后1、4 d及埋线后1周ROI的T2值均较埋线前显著升高(P<0.05),均可见不同高信号影;埋线后2、3、4、5周ROI的T2值较埋线后1周显著下降(P<0.05),各时间段信号影接近埋线前。丰隆穴埋线后1、4 d及埋线后1、2周ROI的T2值均较埋线前显著升高(P<0.05),均可见不同高信号影;埋线后3、4、5周ROI的T2值较埋线后2周显著下降(P<0.05),各时间段信号影接近埋线前。结论单纯性肥胖患者埋线后穴位刺激效应具有不同的时效特点,天枢约1周,脾俞约2周,丰隆约3周。故单纯性肥胖患者埋线减肥时,建议可参照腹部1周、背部2周、下肢3周的间隔周期治疗。展开更多
目的:探讨温肺固元汤联合穴位埋线在慢阻肺稳定期肺脾气虚证治疗中的应用效果。方法:选取2019年1月至2021年1月期间于本院诊治的60例慢阻肺稳定期肺脾气虚证患者作为研究对象,随机分为对照组和观察组,各30例。对照组接受西医对症治疗和...目的:探讨温肺固元汤联合穴位埋线在慢阻肺稳定期肺脾气虚证治疗中的应用效果。方法:选取2019年1月至2021年1月期间于本院诊治的60例慢阻肺稳定期肺脾气虚证患者作为研究对象,随机分为对照组和观察组,各30例。对照组接受西医对症治疗和温肺固元汤治疗,观察组在对照组基础上联合穴位埋线治疗。两组均连续治疗2m。分析比较两组的中医症状积分、肺功能、急性发作次数、复发率。结果:治疗前,两组的中医症候积分、各项肺功能指标水平比较均无明显差异(P>0.05)。治疗后,观察组的症候积分明显低于对照组(P<0.05);观察组的第1秒用力呼气容积(Forced expiratory volume in the first second,FEV1)、用力肺活量(Forced vital capacity,FVC)、FEV1/FVC各项肺功能指标均明显高于对照组(P<0.05)。治疗后6 m、12 m,观察组的急性发作次数均明显少于对照组(P<0.05)。治疗后2 m,观察组复发率明显低于对照组(P<0.05)。结论:温肺固元汤联合穴位埋线治疗慢阻肺稳定期肺脾气虚证,能促进患者临床症状的缓解,改善肺功能,减少急性发作次数,降低短时复发率。展开更多
文摘Objective:To observe the effects of acupoint thread-embedding therapy on serum apelin and glucagon-like peptide-1(GLP-1)in type 2 diabetes mellitus patients with obesity due to dampness-heat encumbering spleen.Methods:Sixty-six patients were randomly divided into a control group and an observation group according to the random number table method,with 33 cases in each group.Patients in the control group were treated with exenatide and metformin,while patients in the observation group were treated with additional acupoint thread-embedding.After 12-week treatment,the obesity-related indicators,including body mass index(BMI),waist circumference and body fat rate,the glycometabolism indicators,including fasting blood glucose,2 h postprandial blood glucose and glycosylated hemoglobin,and the lipid metabolism indicators,including total cholesterol(TC),triglyceride(TG)and low-density lipoprotein cholesterol(LDL-C),as well as serum apelin and GLP-1 levels were observed in patients of the two groups.Results:After treatment,the BMI,waist circumference and body fat rate of patients in the two groups were all reduced(all P<0.05),and were lower in the observation group than in the control group(all P<0.05);the fasting blood glucose,2 h postprandial blood glucose and glycosylated hemoglobin levels of patients in both groups were all decreased(all P<0.05),and were significantly lower in the observation group than in the control group(all P<0.05);the TC level was decreased(P<0.05),while the TG and LDL-C levels did not change significantly in the control group(both P>0.05);the TC,TG and LDL-C levels were all significantly reduced in the observation group(all P<0.05),lower than those in the control group(all P<0.05);the serum apelin level was decreased(P<0.05)and the serum GLP-1 level was increased(P<0.05)in the observation group,statistically different from those in the control group(both P<0.05).Conclusion:Combined with the conventional medication,acupoint thread-embedding therapy can significantly improve the obesity-related indicators,glycometabolism and lipid metabolism in type 2 diabetes mellitus patients with obesity due to dampness-heat encumbering spleen.This may be achieved by regulating the serum apelin and GLP-1 levels.
文摘Objective:To investigate the effect of acupoint catgut-embedding therapy on non-alcoholic fatty liver disease(NAFLD).Methods:Twenty-three participants were subjected to acupoint catgut-embedding therapy for 3 sessions.The second session was performed one month after the first session and the third session two months after the second session.Three months after the third session of catgut-embedding therapy,the patients were subjected to fibroscan analysis.A total of 20 acupoints were selected in three sessions.Same acupoints were selected for all the patients at the same session but different points were selected at different sessions.Results:Of the 23 participants,5 cases showed significant improvement and 8 cases showed moderate improvement as the steatosis stage was reduced by 1 or 2 degrees.The whole group showed significant improvements in terms of patient score,fat percentage,NAFLD steatosis stage,weight loss and abdominal circumference reduction after acupoint catgut-embedding therapy(all P<0.05).Conclusion:The acupoint catgut-embedding therapy can significantly improve the important factors in patients with NAFLD.
文摘目的基于磁共振成像观察穴位埋线对单纯性肥胖患者局部经穴(天枢、脾俞、丰隆)刺激效应的时效特点。方法应用T2-mapping技术采集15例单纯性肥胖患者左侧天枢、脾俞、丰隆穴埋线前后不同时间段T2WI压脂及T2-mapping 8回波序列图像,传入后处理工作站生成伪彩图,获取信号最强的连续3个层面感兴趣区(region of interest,ROI)的T2值均数,分析天枢、脾俞、丰隆穴局部T2WI压脂序列图像的信号影强弱和T2值随时间变化的特点。结果天枢穴埋线后1、4 d ROI的T2值均较埋线前显著升高(P<0.05),均可见不同高信号影;埋线后1、2、3、4、5周ROI的T2值较埋线后4d显著下降(P<0.05),各时间段信号影接近埋线前。脾俞穴埋线后1、4 d及埋线后1周ROI的T2值均较埋线前显著升高(P<0.05),均可见不同高信号影;埋线后2、3、4、5周ROI的T2值较埋线后1周显著下降(P<0.05),各时间段信号影接近埋线前。丰隆穴埋线后1、4 d及埋线后1、2周ROI的T2值均较埋线前显著升高(P<0.05),均可见不同高信号影;埋线后3、4、5周ROI的T2值较埋线后2周显著下降(P<0.05),各时间段信号影接近埋线前。结论单纯性肥胖患者埋线后穴位刺激效应具有不同的时效特点,天枢约1周,脾俞约2周,丰隆约3周。故单纯性肥胖患者埋线减肥时,建议可参照腹部1周、背部2周、下肢3周的间隔周期治疗。
文摘目的:探讨温肺固元汤联合穴位埋线在慢阻肺稳定期肺脾气虚证治疗中的应用效果。方法:选取2019年1月至2021年1月期间于本院诊治的60例慢阻肺稳定期肺脾气虚证患者作为研究对象,随机分为对照组和观察组,各30例。对照组接受西医对症治疗和温肺固元汤治疗,观察组在对照组基础上联合穴位埋线治疗。两组均连续治疗2m。分析比较两组的中医症状积分、肺功能、急性发作次数、复发率。结果:治疗前,两组的中医症候积分、各项肺功能指标水平比较均无明显差异(P>0.05)。治疗后,观察组的症候积分明显低于对照组(P<0.05);观察组的第1秒用力呼气容积(Forced expiratory volume in the first second,FEV1)、用力肺活量(Forced vital capacity,FVC)、FEV1/FVC各项肺功能指标均明显高于对照组(P<0.05)。治疗后6 m、12 m,观察组的急性发作次数均明显少于对照组(P<0.05)。治疗后2 m,观察组复发率明显低于对照组(P<0.05)。结论:温肺固元汤联合穴位埋线治疗慢阻肺稳定期肺脾气虚证,能促进患者临床症状的缓解,改善肺功能,减少急性发作次数,降低短时复发率。
