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Rapid and Sensitive Chemiluminescent Enzyme Immunoassay for the Determination of Neomycin Residues in Milk 被引量:5
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作者 LUO Peng Jie ZHANG Jian Bo +8 位作者 WANG Hua Li CHEN Xia WU Nan ZHAO Yun Feng WANG Xiao Mei ZHANG Hong ZHANG Ji Yue ZHU Lei JIANG Wen Xiao 《Biomedical and Environmental Sciences》 SCIE CAS CSCD 2016年第5期374-378,共5页
Immunoassays greatly contribute to veterinary drug residue analysis. However, there are few reports on detecting neomycin residues by immunoassay. Here, a rapid and sensitive chemiluminescent enzyme immunoassay (CLIE... Immunoassays greatly contribute to veterinary drug residue analysis. However, there are few reports on detecting neomycin residues by immunoassay. Here, a rapid and sensitive chemiluminescent enzyme immunoassay (CLIEA) was successfully developed for neomycin residue analysis. CLIEA demonstrated good cross-reactivity for neomycin, and the IC50 value was 2.4 ng/mL in buffer. 展开更多
关键词 CLEIA Rapid and Sensitive chemiluminescent Enzyme Immunoassay for the Determination of Neomycin Residues in Milk
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Determination of theophylline concentration in serum by chemiluminescent immunoassay 被引量:2
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作者 周美霞 管茶英 +2 位作者 陈光 谢鑫友 吴盛海 《Journal of Zhejiang University-Science B(Biomedicine & Biotechnology)》 SCIE CAS CSCD 2005年第12期1148-1152,共5页
Objective: This study aimed to establish chemiluminescent immunoassay (CLIA) for quantitative determination of theophylline levels in human serum. Methods: To measure the concentration of theophylline (n=122) and eval... Objective: This study aimed to establish chemiluminescent immunoassay (CLIA) for quantitative determination of theophylline levels in human serum. Methods: To measure the concentration of theophylline (n=122) and evaluate the assay.Results: The linear range of the CLIA method was 0.51~40 mg/L (Y=1.02X+0.44, r=0.995). The intra and inter CV (coefficient variance) of CLIA were 3.20% and 3.57%, respectively. The average recovery rate was 102.3%. This method was free from interference by brilirubin (<200 μmol/L), hemoglobin (<10 g/L), and triglycerides (<15 mmol/L). Conclusion: This method is simple, convenient and precise for clinical pharmacokinetics study oftheophylline. 展开更多
关键词 THEOPHYLLINE chemiluminescent immunoassay (CLIA) Fluorescence polarization immunoassay (FPIA)
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A New Chemiluminescent Triazine Reagent
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作者 Quan Li MA Mei Hong SU +2 位作者 Hui Min MA Zhi Hua WANG Shu Chuan LIANG 《Chinese Chemical Letters》 SCIE CAS CSCD 2001年第3期267-268,共2页
A new chemiluminescent reagent 7-(4,6-dichloro-1,3,5-triazinylamino)-4-methylcoumarin-4-methylcoumarin (DTMC) was synthesized by linking 7-amino-4-methylcoumarin to cyanuric chloride at 0-5 degreesC, and with it a nov... A new chemiluminescent reagent 7-(4,6-dichloro-1,3,5-triazinylamino)-4-methylcoumarin-4-methylcoumarin (DTMC) was synthesized by linking 7-amino-4-methylcoumarin to cyanuric chloride at 0-5 degreesC, and with it a novel chemiluminescence method was developed for the determination of hydrogen peroxide. The selectivity of this method is high, and most of the transition metal ions have no effect on the determination of H2O2. 展开更多
关键词 7-(4 6-dichloro-1 3 5-triazinylamino)-4-methylcoumarin chemiluminescent reagent hydrogen peroxide.
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Covalent Attachment of DNA to Glass Supports Using A New Silane Coupling Agent and Chemiluminescent Detection
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作者 张国军 周宜开 +2 位作者 邬晓燕 袁津玮 任恕 《Journal of Huazhong University of Science and Technology(Medical Sciences)》 SCIE CAS 2000年第2期89-91,共3页
A new kind of silane coupling agent, N- (β-aminoethyl ) - γ-aminopropyl triet hoxysilane, was used for DNA direct attachment on the surfaces of glass supports, then the immobilized DNA was hybridized with horseradis... A new kind of silane coupling agent, N- (β-aminoethyl ) - γ-aminopropyl triet hoxysilane, was used for DNA direct attachment on the surfaces of glass supports, then the immobilized DNA was hybridized with horseradish peroxidase (HRP)-labeled probe, and detected by using enhanced chemiluminescent method. In comparison with γ-aminopropyl triethoxysilane, the detection limits (S/N) of DNA were 10 pg and 75 pg respectively. Several experimental conditions of DNA attachING to glass supports were investigated, and the system of hybridization of nucleic acid on the surfaces of glass supports was developed. 展开更多
关键词 new silane coupling agent DNA attachment glass support nucleic acid hybridization enhanced chemiluminescent detection
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SELECTIVE SULFUR DIOXIDE DETERMINATION BY GAS DIFFUSION FLOW INJECTION ANALYSIS WITH CHEMILUMINESCENT DETECTION
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作者 Yong He BAO Qi Jun SONG Department of Chemistry,XingJiang University,Urumchi,830046 《Chinese Chemical Letters》 SCIE CAS CSCD 1991年第4期313-314,共2页
Sulfur dioxide has been found to decrease the chemiluminescence of luminol-iodine system.A new determination method for sulfur dioxide in atmosphere is developed by applying this reaction to a flow injection gas diffu... Sulfur dioxide has been found to decrease the chemiluminescence of luminol-iodine system.A new determination method for sulfur dioxide in atmosphere is developed by applying this reaction to a flow injection gas diffusion separation system.This permits the determination of sulfur dioxide selectively and rapidly. 展开更多
关键词 FLOW SELECTIVE SULFUR DIOXIDE DETERMINATION BY GAS DIFFUSION FLOW INJECTION ANALYSIS WITH chemiluminescent DETECTION GAS
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Determination of Progesterone Receptor by Chemiluminescent Enzyme Immunoassay
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作者 殷铁军 顾美皎 +3 位作者 周宜开 郑文 胡伟 芦运萍 《Journal of Huazhong University of Science and Technology(Medical Sciences)》 SCIE CAS 2003年第1期60-61,93,共3页
A new method of chemiluminescent enzyme immunoassay (CLEIA) was developed and the standard curve and regression equation for determination of progesterone receptor (PR) made. The luminosity of tissue samples was teste... A new method of chemiluminescent enzyme immunoassay (CLEIA) was developed and the standard curve and regression equation for determination of progesterone receptor (PR) made. The luminosity of tissue samples was tested and PR level was calculated by the regression equation. Correlation analysis revealed that there was a linear relationship between different concentrations of the standard PR samples and the corresponding values of luminosity: Y=3748+463.77X, γ=0 9958. The values of the luminosity in 38 cases of tumor tissues were determined with the highest being 267.32 fmol/mg, the lowest 3.69 fmol/mg and the mean 78.53 fmol/mg. The new method of CLEIA was a stable, creditable,specific and sensitive assay for determination of PR. 展开更多
关键词 progesterone receptor chemiluminescent enzyme immunoassay
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Clinical Performance of SARS-CoV-2 IgG and IgM Tests Using an Automated Chemiluminescent Assay 被引量:3
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作者 Jin-an ZHOU Hao-long ZENG +1 位作者 Ling-yan DENG Hui-jun LI 《Current Medical Science》 SCIE CAS 2021年第2期318-322,共5页
Serology tests for viral antibodies provide an important tool to support nucleic acid testing for diagnosis of the novel coronavirus disease 2019(COVID-19)and is useful for documenting previous exposures to SARS-CoV-2... Serology tests for viral antibodies provide an important tool to support nucleic acid testing for diagnosis of the novel coronavirus disease 2019(COVID-19)and is useful for documenting previous exposures to SARS-CoV-2,the etiological agent of COVID-19.The sensitivities of the chemiluminescent SARS-CoV-2 IgG/IgM immunoassay were assessed by using serum samples collected from 728 patients testing positive for SARS-CoV-2 RNA.The specificity was evaluated on a panel of 60 serum samples from non-COVID-19 patients with high levels of rheumatoid factor,antinuclear antibody,or antibodies against Epstein-Barr virus(EBV),cytomegalovirus(CMV),mycoplasma pneumonia,human respiratory syncytial virus(RSV),adenovirus,influenza A or influenza B.The imprecision and interference were assessed by adopting the Clinical and Laboratory Standards Institute(CLSI)EP15-A2 and EP7-A2,respectively.Sensitivities between 1 and 65 days after onset of symptoms were 94.4%and 78.7%,for IgG and IgM test,respectively.The sensitivity increased with the time after symptom onset,and rose to the top on the 22nd to 28th days.The total imprecision(CVs)was less than 6.0%for IgG and less than 6.5%for IgM.Limited cross-reactions with antibodies against EBV,CMV,mycoplasma pneumonia,human RSV,adenovirus,influenza A or influenza B were found.These data suggested the chemiluminescent SARS-CoV-2 IgG and IgM,assay with reliable utility and sensitivity,could be used for rapid screening and retrospective surveillance of COVID-19. 展开更多
关键词 COVID-19 SARS-CoV-2 IGG IGM CHEMILUMINESCENCE
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Flow Injection Determination of Tramadol Based on Its Sensitizing Effect on the Chemiluminescent Reaction of Permanganate-Sulfite 被引量:1
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作者 Xun Yao Jingkai Zhang Jianguo Li 《American Journal of Analytical Chemistry》 2011年第7期768-775,共8页
In this paper, a novel chemiluminescence (CL) method for the determination of tramadol has been developed by combining the flow injection technique and its sensitizing effect on the weak CL reaction between sulfite an... In this paper, a novel chemiluminescence (CL) method for the determination of tramadol has been developed by combining the flow injection technique and its sensitizing effect on the weak CL reaction between sulfite and acidic KMnO4. A mechanism for the CL reaction has been proposed on the basis of fluorescent and CL spectra. Under the optimized conditions, the proposed method allows the measurement of tramadol hydrochloride over the range of 0.04 - 4 ?g/mLwith a correlation coefficient of 0.9995 (n = 8) and a detection limit of 0.01 ?g/mL (3σ), and the relative standard deviation for 2.0 ?g/mL tramadol (n = 11) is 2.1%. The utility of this method was demonstrated by determining tramadol hydrochloride in tablets and injections. 展开更多
关键词 Chemiluminescence TRAMADOL HYDROCHLORIDE KMNO4 Sodium SULFITE FLOW-INJECTION Analysis
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New Time-resolved-Tween 80 Chemiluminescent System for Simultaneous Determination of Trace Gold and Osmium
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作者 韩鹤友 罗庆尧 余席茂 《Rare Metals》 SCIE EI CAS CSCD 1997年第3期35-40,共6页
A time resolved chemiluminescent analysis for simultaneous determination of trace Au(Ⅲ) and Os(Ⅳ) was proposed. The method is based on the kinetic distinction of Au(Ⅲ) and Os(Ⅳ) in Tween 80 KOH chemilumescent sy... A time resolved chemiluminescent analysis for simultaneous determination of trace Au(Ⅲ) and Os(Ⅳ) was proposed. The method is based on the kinetic distinction of Au(Ⅲ) and Os(Ⅳ) in Tween 80 KOH chemilumescent system. The detection limits were 1.1×10 -9 g/ml for Au(Ⅲ) and 1.0×10 -8 g/ml for Os(Ⅳ), with the linear ranges of 1.0×10 -8 ~1.0×10 -5 g/ml for Au(Ⅲ) and 1.0×10 -7 ~1.0×10 -6 g/ml for Os(Ⅳ). The method was applied to the determination of Au(Ⅲ) and Os(Ⅳ) in the sample of metallurgical materials of noble metals with satisfactory results. 展开更多
关键词 Time resolved CHEMILUMINESCENCE Tween80 Simultaneous determination GOLD OSMIUM
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Determination of Some CarbonylCarboxylic Acids Using Chemiluminescent Reaction of Ru (bipy)_3^(2+)-Ce (Ⅳ)
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《Wuhan University Journal of Natural Sciences》 CAS 1999年第3期326-330,共5页
A coupled chemiluminescence method for the determination of some carhoxylic acids was devel-oped, based on their enhancement the chemiluminescence light emission of the reaction of tirs(2, 2'-bipyri-dine) rutheni... A coupled chemiluminescence method for the determination of some carhoxylic acids was devel-oped, based on their enhancement the chemiluminescence light emission of the reaction of tirs(2, 2'-bipyri-dine) ruthenium(Ⅱ) and Ce(Ⅳ) in sulfuric acid medium. The conditions for their determination were opti-mized. The following detection limits were obtained: oxalic acid, 2. 67×10-8 mol/L; propandioic acld, 1.20×10-6 mol/L; pyruvic acid, 1. 35 ×10-8 mol/L; citric acid, 5.10×10-8. mol/L; barbituric acid, 2.48×10-7,mol/L. The proposed method was successfully applied to determination or oxalic acid. The coupled chemilu-minescent reaction mechanism and rate equation are proposed. 展开更多
关键词 CHEMILUMINESCENCE Ru(bipy)_3^(2+) carbonyl carboxylic acid Ce(Ⅳ)
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Near-infrared Emissive 1,2-Dioxetane-based Chemiluminescent Probes
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作者 CHEN Yingqi BUDIANTA Richard NING Yingying 《Chemical Research in Chinese Universities》 SCIE CAS CSCD 2024年第5期806-823,共18页
Chemiluminescence,a phenomenon emitting light from chemical reactions rather than photon absorption,has gained significant interest for applications in bioimaging and biosensing due to its high sensitivity and low bac... Chemiluminescence,a phenomenon emitting light from chemical reactions rather than photon absorption,has gained significant interest for applications in bioimaging and biosensing due to its high sensitivity and low background interference.Now there is a growing interest in near-infrared(NIR)chemiluminescent probes for improved tissue penetration and reduced autofluorescence.This review summarizes NIR emissive chemiluminescent probes based on 1,2-dioxetane and discusses their chemical structures and applications.Structure modification strategies for red-shifting wavelength and enhancing brightness include incorporating electron-withdrawing groups,designing chemiluminophore-fluorophore cassettes,and exploring alternative chemiluminescent scaffolds.This review aims to inspire the exploration of NIR chemiluminescent probes in disease detection and treatment. 展开更多
关键词 CHEMILUMINESCENCE NEAR-INFRARED DIOXETANE BIOIMAGING BIOSENSING
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Rational design multi-color-emissive chemiluminescent carbon nanodots in a single solvothermal reaction
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作者 Guang-Song Zheng Cheng-Long Shen +5 位作者 Yuan Deng Kai-Kai Liu Jin-Hao Zang Lin Dong Qing Lou Chong-Xin Shan 《Nano Research》 SCIE EI CSCD 2024年第6期4651-4660,共10页
Recently,the chemiluminescence(CL)induced by carbon nanodots(CDs)has intrigued researchers’extensive interests in various applications due to its special light emission principle.However,the difficulty of synthesizin... Recently,the chemiluminescence(CL)induced by carbon nanodots(CDs)has intrigued researchers’extensive interests in various applications due to its special light emission principle.However,the difficulty of synthesizing chemiluminescent CDs with full-spectrum emission severely hinders the further regulation of the CL emission mechanism.Herein,the multi-color-emissive chemiluminescent CDs are rational designed and further synthesized by regulating the sp2-hybrid core and sp3-hybrid surface from the citrate-ammonia molecular in a single solvothermal reaction.More experimental characterizations and density functional theory calculations reveal that the higher temperature can promote the crosslinking polymerization/carbonization of carbon core and the higher protonation of solvent can determine the core size of final CDs,resulting in the variant CL emission from molecular-,crosslinking-and core-states.Thus,the CL emission of the CDs can be further synthesized by tuning the luminescence chromophores in the formation process via regulating the temperature and solvent,enabling the applications of the CL CDs in illumination and information encryption.This study paves a new technology to understand the luminescence of CDs and affords an industry translational potential over traditional chemiluminescent molecular. 展开更多
关键词 carbon nanodots CHEMILUMINESCENCE REGULATION energy level alignment mechanism
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Cloud-based smartphone-assisted chemiluminescent assay for rapid screening of electroactive bacteria 被引量:1
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作者 WEN JunLin HE DaiGui +2 位作者 LUO SongQing ZHOU ShunGui YUAN Yong 《Science China(Technological Sciences)》 SCIE EI CAS CSCD 2023年第3期743-750,共8页
Electroactive bacteria(EAB)can transfer electrons to exocellular solid acceptors and have widespread applications in the fields of pollutant degradation,biosynthesis,and hydrogen generation.Traditional EAB screening m... Electroactive bacteria(EAB)can transfer electrons to exocellular solid acceptors and have widespread applications in the fields of pollutant degradation,biosynthesis,and hydrogen generation.Traditional EAB screening methods can precisely measure the bacterial extracellular electron transfer ability,but they suffer from time-consuming and labor-intensive procedures.The chemiluminescence technique is effective for the rapid detection of hemoglobin but has not been applied for EAB screening.Herein,we utilized a chemiluminescent assay to identify EAB through a multiheme c-type cytochrome(c-Cyt)triggered chemiluminescent reaction.The multiheme c-Cyts-triggered chemiluminescence was conveniently determined by taking photographs with commercial smartphones and cloud-based computing.The acquired image signal shows a significant and linear relationship with the bacterial concentration.Measurement results of the chemiluminescence intensity triggered by different bacterial species with the proposed method are strongly associated with those of the microplate reading method(Pearson’s r of 0.9795;P<0.01)and dissimilatory Fe(Ⅲ)reduction method(Pearson’s r of 0.9628;P<0.01).Furthermore,this cloud-based and smartphone-assisted chemiluminescent assay is instrument-free and easy to operate,and results can be obtained within 2 min.The findings demonstrate that the proposed method can effectively detect EAB.Therefore,it will be an alternative approach for EAB screening and can have promising applications in microbiology,environmental science,and bioenergy. 展开更多
关键词 electroactive bacteria c-type cytochrome CHEMILUMINESCENCE cloud computing SMARTPHONE
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DNAzyme@CuSNPs dual mimic enzyme probe-amplified chemiluminescent imaging array immunosensor for multiple chicken cytokines detection
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作者 Jingyi Zhan Feng Shi +4 位作者 Juan Li Hao Zeng Ming Chen Xiaoya Hu Zhanjun Yang 《Chinese Chemical Letters》 SCIE CAS CSCD 2023年第12期505-508,共4页
The detection of cytokines plays an important role in clinical diagnosis and immune mechanism research of chicken diseases.In this work,a novel and ultrasensitive chemiluminescent(CL)imaging array immunosensor was pro... The detection of cytokines plays an important role in clinical diagnosis and immune mechanism research of chicken diseases.In this work,a novel and ultrasensitive chemiluminescent(CL)imaging array immunosensor was proposed to detect multiple chicken cytokines based on DNAzyme@CuS nanoparticles(DNAzyme@CuSNPs)dual mimic enzyme signal amplification strategy.DNAzyme@CuSNPs owns excellent peroxidase property,which was modified with second antibody(Ab_(2))to prepare DNAzyme@CusNPs detection probe,and demonstrated high catalysis CL imaging signal due to synergistic catalysis.Chicken interleukin-4(ChIL-4)and chicken interferon-y(ChIFN-y)were used as model analysis samples,the DNAzyme@CusSNPs-based CL imaging immunosensor achieved simultaneous and high-throughput detection of ChIL-4 and ChIFN-y with wide linear range of 10^(-3)-10^(2) ng/mL,and the detection limits are 0.41 pg/mL and 0.36 pg/mL,respectively.The multiplex chicken cytokines CL imaging array immunosensor shows a high sensitivity,wide linear range,excellent specificity and acceptable stability.This research opens dual mimic enzyme signal-amplified strategy to develop sensitive CL imaging immunoassay for chicken diseases detection application. 展开更多
关键词 DNAzyme@CuSNPs Dual mimic enzyme Signal amplification CHEMILUMINESCENCE Array sensor Chicken cytokines
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Integration of cryogenic trap to gas chromatography-sulfur chemiluminescent detection for online analysis of hydrogen gas for volatile sulfur compounds 被引量:5
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作者 Yi Pan Fan-Feng Deng +3 位作者 Zheng Fang Han-Jiao Chen Zhou Long Xian-Deng Hou 《Chinese Chemical Letters》 SCIE CAS CSCD 2021年第11期3440-3445,共6页
Hydrogen fuel cells are among the promising energy sources worldwide,which could accomplish cyclic production of energy and avoid the emission of green-house or contaminative byproducts.However,sulfur compounds(SCs)ev... Hydrogen fuel cells are among the promising energy sources worldwide,which could accomplish cyclic production of energy and avoid the emission of green-house or contaminative byproducts.However,sulfur compounds(SCs)even at trace level(nmol/mol)are usually involved in cell construction and further H_(2)production,which would cause degradation of the catalysts and shorten the lifetime of the fuel cells.Moreover,the highly reactive SCs could cause varied species and concentrations of them in complex matrices,so online rather than offline analysis of SCs in H_(2)would be preferred.In this context,we developed a new system combining online cryogenic preconcentration of nine SCs and subsequent determination by GC-SCD(sulfur chemiluminescent detector),with the correlation coefficients of the calibration curves higher than 0.999,calculated limits of detection no higher than 0.050 nmol/mol,analytical time around 30 min per sample,and satisfactory precision and accuracy(RSD<5%and SD<15%).The analytical performance was much better than or at least comparable to the previously reported and the developed system was successfully applied for real sample analysis. 展开更多
关键词 GAS-CHROMATOGRAPHY Hydrogen fuel cell Online cryogenic trap Sulfur chemiluminescent detector Volatile sulfur compounds
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Insight into structure evolution of carbon nitrides and its energy conversion as luminescence
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作者 Hao Zhang Jingwei Zhang +4 位作者 Wenjie Chen Minjia Tao Xianguang Meng Yuanjian Zhang Guifu Zuo 《Carbon Energy》 SCIE EI CAS CSCD 2024年第2期37-60,共24页
A series of carbon nitride(CN)materials represented by graphitic carbon nitride(g-C_(3)N_(4))have been widely used in bioimaging,biosensing,and other fields in recent years due to their nontoxicity,low cost,and high l... A series of carbon nitride(CN)materials represented by graphitic carbon nitride(g-C_(3)N_(4))have been widely used in bioimaging,biosensing,and other fields in recent years due to their nontoxicity,low cost,and high luminescent quantum efficiency.What is more attractive is that the luminescent properties such as wavelength and intensity can be regulated by controlling the structure at the molecular level.Hence,it is time to summarize the related research on CN structural evolution and make a prospect on future developments.In this review,we first summarize the research history and multiple structural evolution of CN.Then,the progress of improving the luminescence performance of CN through structural evolution was discussed.Significantly,the relationship between CN structure evolution and energy conversion in the forms of photoluminescence,chemiluminescence,and electrochemiluminescence was reviewed.Finally,key challenges and opportunities such as nanoscale dispersion strategy,luminous efficiency improving methods,standardization evaluation,and macroscopic preparation of CN are highlighted. 展开更多
关键词 carbon nitride CHEMILUMINESCENCE ELECTROCHEMILUMINESCENCE energy conversion PHOTOLUMINESCENCE structural evolution
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Optical molecular imaging in cancer research:current impact and future prospect
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作者 Yinuo Li Zihan Li +4 位作者 Yuting Li Xiaofan Gao Tian Wang Xiangyi Ma Mingfu Wu 《Oncology and Translational Medicine》 CAS 2024年第5期212-222,共11页
Cancer has long been amajor threat to human health.Recent advancements inmolecular imaging have revolutionized cancer research by enabling early and precise disease localization,essential for effective management.In p... Cancer has long been amajor threat to human health.Recent advancements inmolecular imaging have revolutionized cancer research by enabling early and precise disease localization,essential for effective management.In particular,optical molecular imaging is an invaluable cancer detection tool in preoperative planning,intraoperative guidance,and postoperative monitoring owing to its noninvasive nature,rapid turnover,safety,and ease of use.The tumor microenvironment and cells within it express distinct biomarkers.Optical imaging technology leverages these markers to differentiate tumor tissues from surrounding tissues and capture real-time images with high resolution.Nevertheless,a robust understanding of these cancer-relatedmolecules and their dynamic changes is crucial for effectivelymanaging cancer.Recent advancements in opticalmolecular imaging technologies offer novel approaches for cancer investigation in research and practice.This review investigates themodern opticalmolecular imaging techniques employed in both preclinical and clinical research,including bioluminescence,fluorescence,chemiluminescence,photoacoustic imaging,and Raman spectroscopy.We explore the current paradigm of optical molecular imaging modalities,their current status in preclinical cancer research and clinical applications,and future perspectives in the fields of cancer research and treatment. 展开更多
关键词 CANCER Opticalmolecular imaging Bioluminescence imaging FLUORESCENCE CHEMILUMINESCENCE Photoacoustic imaging Raman spectroscopy
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A specific and selective chemiluminescent probe for Pd^(2+) detection
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作者 Yuqi Gao Yuxing Lin +5 位作者 Tingting Liu Xiaomeng Zhang Feng Xu Pan Liu Lupei Du Minyong Li 《Chinese Chemical Letters》 SCIE CAS CSCD 2019年第1期63-66,共4页
As an important transition metal catalyst, palladium is extensively used in many areas including electronics industry, petroleum industry, automobile industry and fine chemicals engineering. However,it brings harm to ... As an important transition metal catalyst, palladium is extensively used in many areas including electronics industry, petroleum industry, automobile industry and fine chemicals engineering. However,it brings harm to the environment as well as people's health. Herein, we managed to introduce a butynyl group to 1,2-dioxetane developing a reaction-based chemiluminescent probe as well as an imaging approach for monitoring palladium(II). Exhibiting enhanced total flux in Pd2+enriched areas, palladium chemiluminescent probe(PCL) may afford potential utility for detecting Pd2+in vitro, in cellulo and in vivo. 展开更多
关键词 chemiluminescent imaging CHEMILUMINESCENCE 1 2-Dioxetane Palladium(Ⅱ) BIOASSAYS
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Chemiluminescent Determination of Cyromazine in Milk Samples Using Copper(III) Chelate-Triton X-100 by Flow Injection Analysis 被引量:2
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作者 Muhammad ASGHAR Mohammad YAQOOB Abdul NABI 《Chemical Research in Chinese Universities》 SCIE CAS CSCD 2017年第3期354-359,共6页
Cyromazine(CYR) was determined in milk samples using copper(HI) chelate-Triton X-100 chemiluminescence(CL) system associated with flow-injection(FI) in KOH medium. The relative CL intensity for CYR concentrati... Cyromazine(CYR) was determined in milk samples using copper(HI) chelate-Triton X-100 chemiluminescence(CL) system associated with flow-injection(FI) in KOH medium. The relative CL intensity for CYR concentration was linear over the range of 5×10^-4-10μg/mL(R2=0.9990, n=11) with injection rate of 160 h-1 and the relative standard deviation(RSD, n=4) of 1.2%-2.6%. The limit of detection(LOD) for signal-to-noise ratio of 3 was 1.5×10^4μg/mL. The influences of key chemical and physical parameters, some major fresh water ions at their maximum admissible concentrations and a number of pesticides were examined as potential interferences. The concentrations of CYR in spiked milk samples were successfully determined by the proposed method and the results were in good agreement with that of the previously reported HPLC method, having recovery range of (92% a=4%)-(106% a:2%). The possible CL reaction mechanism for copper(m) chelate-Triton X-100-CYR was also briefly discussed. 展开更多
关键词 CHEMILUMINESCENCE Flow injection analysis CYROMAZINE Milk sample
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Near-infrared chemiluminescent carbon nanogels for oncology imaging and therapy 被引量:3
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作者 Chenglong Shen Tianci Jiang +13 位作者 Qing Lou Wenbo Zhao Chaofan Lv Guangsong Zheng Hangrui Liu Pengfei Li Lingling Dai Kaikai Liu Jinhao Zang Feng Wang Lin Dong Songnan Qu Zhe Cheng Chongxin Shan 《SmartMat》 2022年第2期269-285,共17页
Carbon nanogels(CNGs)with dual ability of reactive oxygen species(ROS)imaging and photodynamic therapy have been designed with selfassembled chemiluminescent carbonized polymer dots(CPDs).With efficient deep-red/near-... Carbon nanogels(CNGs)with dual ability of reactive oxygen species(ROS)imaging and photodynamic therapy have been designed with selfassembled chemiluminescent carbonized polymer dots(CPDs).With efficient deep-red/near-infrared chemiluminescence(CL)emission and distinctive photodynamic capacity,the H2O2-driven chemiluminescent CNGs are further designed by assembling the polymeric conjugate and CL donors,enabling an in vitro and in vivo ROS bioimaging capability in animal inflammation models and a high-performance therapy for xenograft tumors.Mechanistically,ROS generated in inflammatory sites or tumor microenvironment can trigger the chemically initiated electron exchange luminescence in the chemical reaction of peroxalate and H2O2,enabling in vivo CL imaging.Meanwhile,part of the excited-state electrons will transfer to the ambient H2O or dissolved oxygen and in turn lead to the type I and type II photochemical ROS production of hydroxyl radicals or singlet oxygen,endowing the apoptosis of tumor cells and thus enabling cancer therapy.These results open up a new avenue for the design of multifunctional nanomaterials for bioimaging and antienoplastic agents. 展开更多
关键词 cancer therapy carbon nanogels CHEMILUMINESCENCE inflammation imaging
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