期刊文献+

二次检索

题名
关键词
文摘
作者
第一作者
机构
刊名
分类号
参考文献
作者简介
基金资助
栏目信息
共找到3,427篇文章
< 1 2 172 >
每页显示 20 50 100
Glutamatergic CYLD deletion leads to aberrant excitatory activity in the basolateral amygdala:association with enhanced cued fear expression
1
作者 Huidong Li Faqin Li +8 位作者 Zhaoyi Chen Erwen Wu Xiaoxi Dai Danni Li Haojie An Shiyi Zeng Chunyan Wang Li Yang Cheng Long 《Neural Regeneration Research》 SCIE CAS 2025年第11期3259-3272,共14页
Neuronal activity,synaptic transmission,and molecular changes in the basolateral amygdala play critical roles in fear memory.Cylindromatosis(CYLD)is a deubiquitinase that negatively regulates the nuclear factor kappa-... Neuronal activity,synaptic transmission,and molecular changes in the basolateral amygdala play critical roles in fear memory.Cylindromatosis(CYLD)is a deubiquitinase that negatively regulates the nuclear factor kappa-B pathway.CYLD is well studied in non-neuronal cells,yet underinvestigated in the brain,where it is highly expressed.Emerging studies have shown involvement of CYLD in the remodeling of glutamatergic synapses,neuroinflammation,fear memory,and anxiety-and autism-like behaviors.However,the precise role of CYLD in glutamatergic neurons is largely unknown.Here,we first proposed involvement of CYLD in cued fear expression.We next constructed transgenic model mice with specific deletion of Cyld from glutamatergic neurons.Our results show that glutamatergic CYLD deficiency exaggerated the expression of cued fear in only male mice.Further,loss of CYLD in glutamatergic neurons resulted in enhanced neuronal activation,impaired excitatory synaptic transmission,and altered levels of glutamate receptors accompanied by over-activation of microglia in the basolateral amygdala of male mice.Altogether,our study suggests a critical role of glutamatergic CYLD in maintaining normal neuronal,synaptic,and microglial activation.This may contribute,at least in part,to cued fear expression. 展开更多
关键词 basolateral amygdala cued fear expression cylindromatosis deubiquitinase glutamate receptor 1 glutamatergic neuron microglial activation N-methyl-D-aspartate receptor 1 neuronal activation synaptic transmission
下载PDF
Fear of Cancer Recurrence in Women with Gynecological Cancer:A Systematic Review
2
作者 Şerife Büyükokudan Öznur Körükcü 《Psycho-Oncologie》 SCIE 2024年第3期147-158,共12页
Although some types of gynecological cancer have a poor prognosis and high recurrence rate,less is known about the fear of cancer recurrence(FCR)in gynecological cancer patients than in other cancer populations.Psycho... Although some types of gynecological cancer have a poor prognosis and high recurrence rate,less is known about the fear of cancer recurrence(FCR)in gynecological cancer patients than in other cancer populations.Psychosocial problems may be experienced more in gender-specific cancers.In order to prevent future health problems related to FCR,it is critical to identify the factors affecting FCR in different subgroups and to develop various interventions.The aim of this study was to review the literature on the factors affecting the FCR in women diagnosed with gynecological cancer and interventions to reduce the FCR.The protocol of this review was registered with PROSPERO(Registration number:CRD42023452570).A total of 18 studies from 10 different countries were included in the systematic review by searching on the PubMed,ScienceDirect,Ovid,Sage,Scopus,Taylor&Francis,Web of Science,CINAHL Complete,and Cochrane databases were searched in English between July-August 2023 without year limitation to identify studies on FCR in women with gynecological cancer.Data from eligible articles were extracted and appraised for quality by two independent reviewers.In addition,bibliometric analysis method was used to visually map the studies on FCR in women with gynecological cancer according to the most frequently repeated keyword,number of citations,most cited author and publication year.Thefindings of the study are categorized and interpreted under two headings,“Interventions affecting FCR”and“Factors influencing FCR”.Sociodemographic characteristics such as age,economic status,social support,family history of cancer,psychological characteristics,quality of life and symptoms affect FCR.Deterioration in mental health and emotional weakness predict higher FCR,increase in positive emotional expression reduces FCR.The negative effects of cancer on sexuality and relationships,concerns about future treatments and emotional problems,and anxiety about not being able to fulfill their roles at home/work are the underlying reasons for the FCR.Therefore,professional psychosocial support should be provided to cancer survivors.Further studies are needed to identify the factors that trigger FCR and to plan interventions accordingly.This study is expected to encourage health professionals to plan interventions and research for gynecological cancer survivors. 展开更多
关键词 GYNECOLOGY CANCER RECURRENCE systematic review fear
下载PDF
Research on the Association between Fear of Cancer Recurrence in Young Breast Cancer Patients and Adult Attachment and Self-Disclosure
3
作者 Huimin Zheng Minghui Wang Miao Ye 《Psycho-Oncologie》 SCIE 2024年第3期169-179,共11页
Background:Although fear of cancer recurrence(FCR)is the most important factor affecting the life quality of young breast cancer patients,and it may be affected by the patient’s personality,marital relationship and c... Background:Although fear of cancer recurrence(FCR)is the most important factor affecting the life quality of young breast cancer patients,and it may be affected by the patient’s personality,marital relationship and communication,there is a lack of research on the relationship between adult attachment,self-disclosure and FCR in patients.This study investigated the current situation of FCR in young breast cancer patients,its correlation with adult attachment and self-disclosure and its influencing factors,in order to predict the impact of adult attachment and self-disclosure of patients to spouse on FCR.Methods:A survey was conducted on 126 breast cancer patients at our hospital using the General Information Questionnaire(GIQ),Fear of Progression Questionnaire-Short Form(FoP-Q-SF),Experiences in Close Relationships inventory(ECR),and Distress Disclosure Index(DDI).The study analyzed the status of FCR among young breast cancer patients and its correlation with adult attachment and self-disclosure,along with its influencing factors.Results:Among the 126 young breast cancer patients,50 had a FoP-Q-SF score<34(normal group),while 76 had a FoP-Q-SF score≥34(FCR positive group),with an FCR incidence rate of 60.32%.Univariate analysis showed statistically significant differences between the two groups in terms of FoP-Q-SF score,ECR score,attachment anxiety score,attachment avoidance score,DDI score,age,educational level,employment status,per capita monthly income,and treatment method(p<0.05).Correlation analysis revealed that FoP-Q-SF scores were positively correlated with attachment anxiety score,attachment avoidance score,ECR scores and negatively correlated with DDI scores(p<0.05).Linear regression analysis indicated that age,per capita monthly income,treatment method,attachment anxiety,attachment avoidance and self-disclosure level were negative predictors of FoP-Q-SF scores in young breast cancer patients(p<0.05).Conclusion:The incidence rate of FCR among young breast cancer patients is high.There is a positive correlation between adult attachment and the level of FCR,and a negative correlation between the level of self-disclosure and FCR.Patients with lower per capita monthly income,more complex treatment methods,higher level of attachment anxiety,higher level of attachment avoidance and lower DDI scores had higher FoP-Q-SF scores. 展开更多
关键词 Breast cancer fear of recurrence adult attachment SELF-DISCLOSURE
下载PDF
The Relationship between Self-Esteem and Social Phobia among College Students:The Mediating Effect of Fear of Negative Evaluation and the Moderating Effect of Perfectionism
4
作者 Shuai Lv Zhaojun Chen +3 位作者 Jian Mao Hui Wang Peibo Wu Yujuan Hai 《International Journal of Mental Health Promotion》 2024年第6期491-498,共8页
Objectives:To explore the relationship between college students’self-esteem(SE)and their social phobia(SP),as well as the mediating role of fear of negative evaluation(FNE)and the moderating effect of perfectionism.M... Objectives:To explore the relationship between college students’self-esteem(SE)and their social phobia(SP),as well as the mediating role of fear of negative evaluation(FNE)and the moderating effect of perfectionism.Methods:A convenience sampling survey was carried out for 1020 college students from Shandong Province of China,utilizing measures of college students’self-esteem,fear of negative evaluation,perfectionism,and social phobia.Data analysis was performed using the SPSS PROCESS macro.Results:(1)college students’self-esteem significantly and negatively predicts their social phobia(β=−0.31,t=−10.10,p<0.001);(2)fear of negative evaluation partially mediates the relation between self-esteem and social phobia among college students,with the mediating effect accounting for 48.97%of the total effect(TE);(3)the mediating role of fear of negative evaluation is moderated by perfectionism(β=0.18,t=7.75,p<0.001),where higher levels of perfectionism strengthen the mediating effect of fear of negative evaluation.Conclusions:Perfectionism moderates the mediating effect that fear of negative evaluation plays,establishing a moderated mediating model. 展开更多
关键词 SELF-ESTEEM fear of negative evaluation PERFECTIONISM social phobia
下载PDF
Resilience provides mediating effect of resilience between fear of progression and sleep quality in patients with hematological malignancies
5
作者 Yuan Tian Ying-Li Wang 《World Journal of Psychiatry》 SCIE 2024年第4期541-552,共12页
BACKGROUND Hematological tumors are common malignant tumors,with high morbidity and mortality rates.Most patients with hematological malignancies develop sleep disorders that seriously affect their life and health bec... BACKGROUND Hematological tumors are common malignant tumors,with high morbidity and mortality rates.Most patients with hematological malignancies develop sleep disorders that seriously affect their life and health because of acute onset of disease,rapid progression,high recurrence rates,complex treatment methods,and treatment costs.AIM To explore the mediating effect of resilience on fear of disease progression and sleep quality in patients with hematological malignancies.METHODS A cross-sectional analysis of 100 patients with hematological malignancies,treated in the First Affiliated Hospital of Jinzhou Medical University between August 2022 and August 2023,was conducted.Patients were assessed using a general data survey,a simplified scale for the fear of progression(FoP)of disease,a resilience scale,and the Pittsburgh Sleep Quality Index.Statistical analysis was conducted to determine the relationship between various patient characteristics and FoP,resilience,and sleep quality.Spearman’s correlation analysis was used to examine the correlations between mental resilience,FoP,and sleep quality.RESULTS The total FoP score mean value in patients with hematological malignancies was 38.09±5.16;the total resilience score mean value was 40.73±7.04;and the Pittsburgh Sleep Quality Index score mean value was 10.72±1.90.FoP,resilience,and sleep quality of the patients were associated with family per capita monthly income and patient education level(P<0.05).Spearman correlation analysis revealed that FoP was negatively correlated with resilience and sleep quality scores(r=-0.560,-0.537,P<0.01),respectively,and resilience was significantly associated with sleep quality scores(r=0.688,P<0.01).Mediation analysis showed that the mediating effect of resilience between FoP and sleep quality in patients with hematological malignancies was-0.100 and accounted for 50.51%of the total effect.This indicated that FoP directly and indirectly affected sleep quality through the mesomeric effect of resilience.CONCLUSION Resilience is an intermediary variable between FoP and sleep quality in patients with hematological malignancies.Medical staff should evaluate and follow-up FoP and resilience to implement measures to improve sleep quality. 展开更多
关键词 RESILIENCE Blood tumor fear of progression Sleep quality Mediating effect
下载PDF
The Impact of Nursing Staff’s Work Attitude on the Fear of Patients Recovering from Benign Tumors:Family Support as a Mediating Variable
6
作者 Chengzhe Guo Aihua Cheng +1 位作者 Jian Chen Gaojie Cheng 《Psycho-Oncologie》 SCIE 2024年第4期291-303,共13页
The perception of nursing staff’s attitude influences patient fear.Understanding this dynamic is crucial for fostering a supportive environment conducive to patient well-being and effective healthcare practices.The p... The perception of nursing staff’s attitude influences patient fear.Understanding this dynamic is crucial for fostering a supportive environment conducive to patient well-being and effective healthcare practices.The purpose of this research is to investigate how the attitudes and behaviours of nursing staff influence the fear and anxiety levels of patients recovering from benign tumors,aiming to improve patient care and recovery outcomes.Data was collected from a sample of 100 participants,comprising 20 nursing staff and 80 patients recovering from benign tumors.Surveys were administered to gather quantitative data on attitudes and fear levels.Participants were selected randomly from hospital records and outpatient clinics.Our analysis encompassed nursing staff attitude,patient fear levels,the influence of family support,progression of tumor recovery,patient-reported satisfaction,and the quality of healthcare services provided.The quantitative aspect utilized PLS-SEM software to perform regression analysis,evaluating both direct and indirect effects.Statistical analysis assessed the relationships between nursing staff attitudes,patient fear during benign tumor recovery,and the mediating role of family support.The findings of the study demonstrate that better nurse attitudes(Hypothesis 1,β=0.45,p<0.001)and stronger family support(Hypothesis 2,β=0.32;p<0.001) are linked to lower levels of patient fear.Partially mediating the relationship between nurse attitudes and patient fear,according to Hypothesis 3(β=0.28,p<0.002),is family support.Patients’perceptions of family support are highly influenced by nursing behaviour,as demonstrated by Hypothesis 4(β=0.38;p<0.001).Our research showed a strong relationship between the attitudes of nursing personnel and patient fear levels.Family support demonstrated a strong mediating effect on patient fear.Patient-reported satisfaction is positively correlated with family support.However,no significant relationship was found between healthcare service quality and patient fear. 展开更多
关键词 Nursing staff’s work attitude fear of patients benign tumors recovery family support statistical analysis
下载PDF
Network Structure and Variability of Recurrence Fear in Early-Stage Non-Small Cell Lung Cancer:A Symptom Network Analysis
7
作者 Lu Liu Zhuoheng Lv +2 位作者 Yousheng Mao Yan Liu Man Liu 《Psycho-Oncologie》 SCIE 2024年第4期317-328,共12页
Background:Lung cancer,one of the most prevalent and deadly malignancies worldwide,not only poses a significant physical burden but also a profound psychological challenge to patients.Among these psychological challen... Background:Lung cancer,one of the most prevalent and deadly malignancies worldwide,not only poses a significant physical burden but also a profound psychological challenge to patients.Among these psychological challenges,the fear of recurrence stands out as a particularly distressing issue.This fear,often rooted in the patients’past experiences with the disease and its treatment,can significantly impact their quality of life,mental health,and even compliance with follow-up care.Moreover,this fear can be exacerbated by the lack of understanding and support from healthcare professionals and family members,further isolating patients and compounding their psychological burden.Therefore,understanding and addressing the fear of recurrence in lung cancer patients is crucial for improving their overall well-being and outcomes.Aims:This study aims to develop a symptom network model for fear of recurrence in early-stage lung cancer patients,analyzing symptom correlations to enhance healthcare providers’understanding and management of these symptoms,thereby improving patient outcomes and quality of life.Design:A cross-sectional study design was used.Method:We employed convenience sampling to recruit 551 lung cancer patients from the Thoracic Surgery Department of a tertiary hospital in Beijing between January 2023 and December 2023.A cross-sectional study was conducted using the General Information Questionnaire,Fear of Disease Progression Scale,and Level of Hope Scale.Network analysis was performed with JASP 0.18.3.0 using the EBICglasso method,and centrality metrics including Betweenness,Closeness,Degree centrality,and Expected influence were calculated.Results:Symptom network analysis identified fear of family impact and future work disruption as central to recurrence fear in these patients.Gender-based analysis revealed‘fear of being unable to continue work’as central in males,while‘fear of affecting family members’was central in females.Among adolescents,concerns about future work,medication side effects,and family impact showed the highest expected influence.In contrast,older patients predominantly feared major treatment implications.One-way ANOVA indicated that older age correlated with reduced recurrence fear,and higher hope levels significantly mitigated this fear.Conclusion:This study broadens understanding of fear of recurrence across demographic variables like gender and age,elucidating symptom interrelations and impacts.Future strategies should focus on patient-specific differences in recurrence fear to formulate targeted interventions.Relevance to Clinical Practice:Through in-depth analysis of the symptom network,healthcare professionals can more comprehensively understand the psychological responses of lung cancer patients when they face the risk of recurrence,and then formulate more precise and personalized treatment plans.At the same time,doctors and nurses can adjust treatment strategies in a timely manner according to the changes in the patient’s symptom network and provide more comprehensive psychological support,thus enhancing the patient’s treatment adherence and outcome.Patient Contribution:People who were invited to participate voluntarily completed a range of questionnaires. 展开更多
关键词 Symptom network recurrence fear early-stage non-small cell lung cancer
下载PDF
Correlation among anxiety and depression,fear of disease progression,and social support in coronary heart disease
8
作者 Yan Xu Han-Xiang Ma +1 位作者 Shan-Shui Liu Qian Gong 《World Journal of Psychiatry》 SCIE 2024年第11期1708-1717,共10页
BACKGROUND The mental well-being of individuals with coronary heart disease(CHD)during the intensive care unit(ICU)transition period is a multifaceted and significant concern.In this phase,the individuals might encoun... BACKGROUND The mental well-being of individuals with coronary heart disease(CHD)during the intensive care unit(ICU)transition period is a multifaceted and significant concern.In this phase,the individuals might encounter psychological challenges like anxiety and depression,which can impede their recuperation and potentially have lasting effects on their health.AIM To investigate the correlation among psychological factors in CHD patients in the ICU transition period.METHODS A questionnaire survey was conducted with 119 patients admitted to the ICU after coronary artery bypass grafting between March and December 2023.Variations in Hamilton Anxiety Scale(HAMA)and Hamilton Depression Scale(HAMD),Fear of Progression Questionnaire-Short Form(Fop-Q-SF),and Social Support Rating Scale(SSRS)were collected and analyzed among diverse populations.We used Pearson’s correlation analysis to examine the correlation.Multiple linear regression analysis was used to explore whether these indicators influenced depression and anxiety in the patients.RESULTS The total scores for anxiety,depression,fear of disease progression,and social support were(7.50±1.41)points,(8.38±1.62)points,(35.19±8.14)points,and(36.34±7.08)points,respectively(P<0.05).Multivariate regression analysis showed that both the level of disease progression and social support affected the level of postoperative depression and anxiety in patients.CONCLUSION The anxiety and depression levels were positively related to each dimension of phobia disease progression and negatively related to each dimension of social support among patients with CHD. 展开更多
关键词 Intensive care unit transition period Coronary heart disease Anxiety and depression fear of disease progression Social support level
下载PDF
The Association between Fear of COVID-19,Obsession with COVID-19,and Post Traumatic Stress Disorder in Korean Emergency Rescue Firefighters:A Cross-Sectional Study
9
作者 Yun-Jung Choi Heewon Song 《International Journal of Mental Health Promotion》 2024年第6期475-480,共6页
During the rapid spread of COVID-19,first responders are at risk of being exposed to COVID-19 due to their role in providing first aid and responding to an unspecified number of people.This uncertainty can have advers... During the rapid spread of COVID-19,first responders are at risk of being exposed to COVID-19 due to their role in providing first aid and responding to an unspecified number of people.This uncertainty can have adverse mental health effects,such as increased anxiety and fear.This study aimed to investigate the degree of association between fear of COVID-19,obsession with COVID-19,and post-traumatic stress disorder(PTSD)in emergency rescue firefighters.The participants were 150 emergency rescue firefighters working in Region S,Korea.They filled out self-report questionnaires:The data obtained through the Fear of COVID-19 Scale,Obsession with COVID-19 Scale,and Impact of Event Scale-Revised Korean version were subjected to nonparametric statistical analysis using SPSS WIN 25.0.The study found a significant correlation between emergency rescue firefighters’fear of COVID-19,obsession with COVID-19,and PTSD.Fear and obsession with COVID-19 were higher among first responder firefighters who were directly involved in COVID-19-related tasks.Furthermore,a one-point increase in obsession was associated with a 2.837-point increase in PTSD.Based on the results,we found that there is a need for effective control of obsessions and fears among first responder firefighters during COVID-19,and we suggest that there is a need for mental health care for first responder firefighters during the pandemic through the development and support of programs to prevent and mitigate obsessions. 展开更多
关键词 COVID-19 emergency rescue firefighters fear of COVID-19 mental health promotion obsession with COVID-19 PTSD
下载PDF
Research Status of Fear of Cancer Recurrence in Breast Cancer Patients
10
作者 Yun Ding Liping Zhang +1 位作者 Lijuan Zhang Qiaoling Zhong 《Journal of Cancer Therapy》 2024年第9期311-319,共9页
Fear of disease progression is one of the most common psychological problems in the treatment of cancer patients. Early recognition and intervention can effectively control the level of fear of disease progression and... Fear of disease progression is one of the most common psychological problems in the treatment of cancer patients. Early recognition and intervention can effectively control the level of fear of disease progression and improve the quality of life of patients. The present situation and influencing factors of FoP in breast cancer patients were reviewed in this paper, in order to provide reference for clinical research of breast cancer patients. 展开更多
关键词 fear of Cancer Recurrence Breast Cancer CANCER NURSING
下载PDF
Qualitative Analysis of a Diffusive Predator-prey Model with Nonlcoal Fear Effect
11
作者 Shen Zhongyuan Zhang Xuebing Li Shunjie 《数学理论与应用》 2024年第3期67-82,共16页
In this paper,we establish a delayed predator-prey model with nonlocal fear effect.Firstly,the existence,uniqueness,and persistence of solutions of the model are studied.Then,the local stability,Turing bifurcation,and... In this paper,we establish a delayed predator-prey model with nonlocal fear effect.Firstly,the existence,uniqueness,and persistence of solutions of the model are studied.Then,the local stability,Turing bifurcation,and Hopf bifurcation of the constant equilibrium state are analyzed by examining the characteristic equation.The global asymptotic stability of the positive equilibrium point is investigated using the Lyapunov function method.Finally,the correctness of the theoretical analysis results is verified through numerical simulations. 展开更多
关键词 Delay Nonlocal fear effect Global stability Hopf bifurcation
下载PDF
Dynamical Behaviors of a Modified Leslie-Gower Predator-Prey System with Fear Effect and Prey Refuge
12
作者 Ke Yuan 《Open Journal of Modelling and Simulation》 2024年第4期184-202,共19页
In this paper, the dynamical behaviors of a modified Leslie-Gower predator-prey model incorporating fear effect and prey refuge are investigated. We delve into the construction of the model and its biological signific... In this paper, the dynamical behaviors of a modified Leslie-Gower predator-prey model incorporating fear effect and prey refuge are investigated. We delve into the construction of the model and its biological significance, with preliminary results encompassing positivity, boundedness, and persistence. The stability of the system’s boundary and positive equilibrium points is proven by calculating the real part of the eigenvalues of the Jacobian matrix. At the positive equilibrium point, we demonstrate that the system’s unique positive equilibrium is globally asymptotically stable by using the Dulac criterion. Furthermore, at this equilibrium point, we employ the Implicit Function Theorem to discuss how fear effects and prey refuges influence the population densities of both prey and predators. Finally, numerical simulations are conducted to validate the above-mentioned conclusions and explored the impact of Predator-taxis sensitivity αon dynamics of the system. 展开更多
关键词 fear Effect Prey Refuge Predator-Taxis Sensitivity Population Density Stability
下载PDF
Muscle Strength, Lumbar Curve, Fear of Movement and Functional Disability among Patients with Lumbar Disc Herniation: A Review
13
作者 G. M. Jakaria Chua Siew Kuan 《Open Journal of Therapy and Rehabilitation》 2024年第1期28-51,共24页
Introduction: Lumbar disc herniation (LDH) refers to the rupture of the fibrous annulus of the intervertebral discs. Lumbar curvature may lead to the occurrence of lumbar disc degeneration. Fear of movement may worsen... Introduction: Lumbar disc herniation (LDH) refers to the rupture of the fibrous annulus of the intervertebral discs. Lumbar curvature may lead to the occurrence of lumbar disc degeneration. Fear of movement may worsen their disc herniation and cause further pain and injury. LDH conditions impact the individuals’ quality of life, to explore the relationship between lumbar curve, muscle strength, fear of movement and functional disability among patients with LDH. Methods: An electronic search was conducted on PubMed, Medline, Science Direct, Springerlink, Google Scholar and a hand search from reference lists was reviewed. Publications were included in human studies, patients 25 - 85 years of age, original studies and published in English language journals from January 2002 to December 2023. Result: In total, 64 articles were researched through the online search engines, and 9 papers were found through manual searches of reference lists. As a result, a total of 11 articles were included for the purpose of this review. The comprehensive analysis revealed the presence of eight cross-sectional studies, two retrospective studies and one experimental study. A minimum of 25 participants and a maximum of 360 participants were included. Ten studies included both genders, only one studies included healthy adults and patients with LDH but these studies didn’t mention gender. Results showed that the factors influencing LDH can be categorized into non-modifiable factors, such as gender, age, height or others. Modifiable factors included increased BMI, DM, smoking, alcohol, employment status, lifestyle and health problems or psychology. Conclusion: Females with greater VASC may be at risk of LDH. The lumbar extensor muscles indicated a localized disc herniation or nerve root pathology in patients with LDH. The fear of movement may lead to psychological consequences and reduce functional disability among patients with LDH. 展开更多
关键词 Lumbar Disc Herniation fear of Movement Functional Disability Vertical Angle of Spinal Curvature
下载PDF
Coping review of dementia fear studies among middle-aged and elderly people in the community
14
作者 Hui Ren Gui-Meng Wang +3 位作者 Wen-Jing Yu Meng-Yuan Teng Jing-Mei Li Xiang-Shu Cui 《Nursing Communications》 2024年第22期1-9,共9页
This study used Arksey and O’Malley’s scoping review methodology as a framework and searched the following databases:PubMed,Embase,EBSCO,CINAHL,Web of Science,Cochrane Library,Scopus,CNKI,Wanfang,VIP,and the Chinese... This study used Arksey and O’Malley’s scoping review methodology as a framework and searched the following databases:PubMed,Embase,EBSCO,CINAHL,Web of Science,Cochrane Library,Scopus,CNKI,Wanfang,VIP,and the Chinese Biomedical Literature Database.The database is open to December 20,2023,and documents related to the fear of dementia among the elderly in the community are described and analyzed to provide a reference for future research in this field.At the same time,we screened,extracted,and summarized relevant information from 21 included documents(16 in English and 5 in Chinese),which consisted of 16 cross-sectional studies,2 quasi-experimental studies,2 randomized controlled studies,and 1 longitudinal study.Sixteen of the included documents mentioned the incidence or level of dementia fear among the elderly in the community,2 addressed the adverse effects of dementia fear,and 4 reported prevention and intervention measures for dementia fear.In total,there are 8 assessment tools,and the influencing factors are categorized into sociodemographic characteristics,psychological and behavioral characteristics,sociocultural background factors,and health and dementia-related factors.The final conclusion is that the fear of dementia is common among the elderly in the community.In the future,the application of research tools should be expanded among middle-aged individuals,with considerations for other types of dementia in mind.It is recommended to conduct large-scale,multi-center randomized controlled trials while confirming the intervention’s effect on different types of middle-aged and elderly individuals,focusing on the long-term impact of these intervention measures to promote healthy aging. 展开更多
关键词 dementia fear middle-aged and elderly people COMMUNITY scope review
下载PDF
Mediating role of fear of progression between sensory processing sensitivity and stigma in lung cancer patients:a cross-sectional study
15
作者 Nan Shen Jiao Yang +5 位作者 Qian-Rong Yang Ruo-Jia Wu Jing Yang Kai-Wen Dong Yan-Qiu Zhao Xiu-Mei Yang 《Frontiers of Nursing》 2024年第4期373-378,共6页
Objective:To explore the association of sensory processing sensitivity(SPS)and stigma as well as the mediating role of fear of progression(FoP)in lung cancer patients.Methods:Two hundred and forty-two lung cancer pati... Objective:To explore the association of sensory processing sensitivity(SPS)and stigma as well as the mediating role of fear of progression(FoP)in lung cancer patients.Methods:Two hundred and forty-two lung cancer patients completed a self-reported questionnaire,which included the highly sensitive person scale(HSPS),fear of progression questionnaire-short form(FoP-Q-SF),and the Cataldo Lung Cancer Stigma Scale(CLCSS).Results:CLCSS was positively correlated with FoP(Pearson correlation=0.217,P<0.01)and HSPS(Pearson correlation=0.187,P<0.01),FoP was positively correlated with HSPS(Pearson correlation=0.199,P<0.01).FoP played a mediating role between SPS and stigma(a×b=0.025,95%confidence intervals[CI][0.004,0.054]),and the proportion of mediating effect(ab/c)was 21%(ab=0.025,c=0.120).Conclusions:Patients with higher SPS reported higher level of stigma,and FoP has a mediating role between SPS and stigma.Our discussion deemed that psychological intervention may help higher SPS patients reduce the harm of FoP and further reduce stigma. 展开更多
关键词 fear of progression lung cancer mediating role sensory processing sensitivity STIGMA
下载PDF
Fear of missing out: A brief overview of origin, theoretical underpinnings and relationship with mental health 被引量:5
16
作者 Mayank Gupta Aditya Sharma 《World Journal of Clinical Cases》 SCIE 2021年第19期4881-4889,共9页
Fear of missing out(FoMO)is a unique term introduced in 2004 to describe a phenomenon observed on social networking sites.FoMO includes two processes;firstly,perception of missing out,followed up with a compulsive beh... Fear of missing out(FoMO)is a unique term introduced in 2004 to describe a phenomenon observed on social networking sites.FoMO includes two processes;firstly,perception of missing out,followed up with a compulsive behavior to maintain these social connections.We are interested in understanding the complex construct of FoMO and its relations to the need to belong and form stable interpersonal relationships.It is associated with a range of negative life experiences and feelings,due to it being considered a problematic attachment to social media.We have provided a general review of the literature and have summarized the findings in relation to mental health,social functioning,sleep,academic performance and productivity,neuro-developmental disorders,and physical well-being.We have also discussed the treatment options available for FoMo based on cognitive behavior therapy.It imperative that new findings on FoMO are communicated to the clinical community as it has diagnostic implications and could be a confounding variable in those who do not respond to treatment as usual. 展开更多
关键词 fear of missing out Mental health Physical well-being Academic performance fear of missing out-reduction Problematic social media
下载PDF
Sevoflurane plays a reduced role in cognitive impairment compared with isoflurane: limited effect on fear memory retention 被引量:9
17
作者 Ying Du Xiang-Dan Gong +3 位作者 Xin Fang Fang Xing Tian-Jiao Xia Xiao-Ping Gu 《Neural Regeneration Research》 SCIE CAS CSCD 2020年第1期96-102,共7页
Isoflurane and sevoflurane are both inhalation anesthetics,but in clinical application,sevoflurane has been considered to be less suitable for long-term anesthesia because of its catabolic compounds and potential neph... Isoflurane and sevoflurane are both inhalation anesthetics,but in clinical application,sevoflurane has been considered to be less suitable for long-term anesthesia because of its catabolic compounds and potential nephrotoxicity.Nevertheless,recent studies have shown that these two inhalation anesthetics are similar in hepatorenal toxicity,cost,and long-term anesthetic effect.Moreover,sevoflurane possibly has less cognitive impact on young mice.In this study,C57BL/6 mice aged 8–10 weeks were exposed to 1.2%isoflurane or 2.4%sevoflurane for 6 hours.Cognitive function and memory were examined in young mice using the novel object recognition,contextual fear conditioning,and cued-fear extinction tests.Western blot assay was performed to detect expression levels of D1 dopamine receptor,catechol-O-methyltransferase,phospho-glycogen synthase kinase-3β,and total glycogen synthase kinase-3βin the hippocampus.Our results show that impaired performance was not detected in mice exposed to sevoflurane during the novel object recognition test.Contextual memory impairment in the fear conditioning test was shorter in the sevoflurane group than the isoflurane group.Long-term sevoflurane exposure did not affect memory consolidation,while isoflurane led to memory consolidation and reduced retention.Downregulation of hippocampal D1 dopamine receptors and phosphorylated glycogen synthase kinase-3β/total glycogen synthase kinase-3βand upregulation of catechol-O-methyltransferase may be associated with differing memory performance after exposure to isoflurane or sevoflurane.These results confirm that sevoflurane has less effect on cognitive impairment than isoflurane,which may be related to expression of D1 dopamine receptors and catechol-O-methyltransferase and phosphorylation of glycogen synthase kinase-3βin the hippocampus.This study was approved by the Institutional Animal Care and Use Committee,Nanjing University,China on November 20,2017(approval No.20171102). 展开更多
关键词 CATECHOL-O-METHYLTRANSFERASE cognitive impairment D1 dopamine receptors fear memory GLYCOGEN synthase kinase-3β ISOFLURANE NEUROTOXICOLOGY SEVOFLURANE
下载PDF
Effects of Abnormal Early Rearing Environments on Fear Memory in Adult Rats
18
作者 李传玉 张波 +3 位作者 李振邦 黄伏连 田绍文 胡新天 《Zoological Research》 CAS CSCD 北大核心 2009年第1期31-37,共7页
In the present experiment, Pavlovian fear conditioning was adopted to study the effects of different early rearing environments on fear conditioning in adult rats. Weaned rats were reared in three manipulable environm... In the present experiment, Pavlovian fear conditioning was adopted to study the effects of different early rearing environments on fear conditioning in adult rats. Weaned rats were reared in three manipulable environments (enriched, social and isolated conditions). After 8 weeks, fear conditioning (characterized by percentage of freezing) was observed and analyzed, and rats' weight, locomoter activity and foot-shock sensitivity were operated too. The results showed that: (1) Compared with control group, the level of conditioned fear was significantly increased in enriched group, but significantly decreased in isolated group; (2) Enriched and isolated conditions influenced rat's weight significantly; (3) Different rearing conditions have no effect on locomoter activity and foot-shock sensitivity. These results indicated that early enriched condition could improve the tone-evoked fear conditioning response, while isolated condition impaired the response. 展开更多
关键词 fear conditioning FREEZING Enriched condition Isolated condition Locomoter activity Foot-shock sensitivity
下载PDF
A comparison of maternal fear of childbirth,labor pain intensity and intrapartum analgesic consumption between primiparas and multiparas:A cross-sectional study 被引量:11
19
作者 Yongfang Deng Yan Lin +5 位作者 Liyuan Yang Qiuxia Liang Bailing Fu Huixian Li Huizhu Zhang Yan Liu 《International Journal of Nursing Sciences》 CSCD 2021年第4期380-387,I0002,共9页
Objectives:To describe and compare fear of childbirth and in-labor pain intensity between primiparas and multiparas and explore the association between the amount of actual pain relief and fear of childbirth.Methods:A... Objectives:To describe and compare fear of childbirth and in-labor pain intensity between primiparas and multiparas and explore the association between the amount of actual pain relief and fear of childbirth.Methods:A convenience sampling method was used.A total of 260 women undergoing spontaneous or induced labor,including 97 primiparas and 163 multiparas,were recruited in a large academic specialized hospital in Guangzhou,China,from February 2018 to August 2019.The clinical data of maternal and neonatal were extracted from a structured electronic medical record system.Other demographic information,such as employment and family monthly income,was collected by a questionnaire.The Numeric Rating Scale(NRS)and the Chinese version of the Childbirth Attitude Questionnaire(C-CAQ)were applied to assess maternal in-labor pain intensity and fear of childbirth.The analgesic consumption and the frequency of manual boluses as rescue analgesia were stored and collected from the analgesia pump.Results:Eighty-two(84.5%)primiparas and ninety-nine(60.7%)multiparas received epidural analgesia(P<0.001).In the epidural subgroup,the primiparous average fear of childbirth(36.46±10.93)was higher than that of the multiparas(32.06±10.23)(P¼0.007).However,multiparas reported more intense in-labor pain[8.0(8.0,9.0)vs.8.0(7.0,8.0)],had more successful manual boluses per hour[2.68(1.65,3.85)vs.1.77(0.90,2.47)],more hourly analgesic consumption[23.00(16.00,28.25)vs.17.24(11.52,21.36)mL]and more average analgesic consumption[0.35(0.24,0.45)vs.0.26(0.19,0.35)mL/(h$kg)]than the primiparas(P<0.05).Spearman’s correlation analysis showed that the maximum in-labor pain was weakly positively correlated with fear of childbirth(r¼0.09)(P<0.05),hourly analgesic consumption(r¼0.16)(P<0.01)and average analgesic consumption(r¼0.17)(P<0.05).No statistically significant association was uncovered between analgesic consumption and maternal fear of childbirth.Conclusions:Fear of childbirth is a potential predictor of labor pain intensity.Further study is needed to explore its role and value in pain management during delivery.Parity is not a determinant of pain relief use and should not be a preconceived preference of obstetric care team members to determine the distribution of epidural analgesia,especially when analgesia resources are insufficient. 展开更多
关键词 Epidural analgesia fear Labor pain Obstetrics and gynecology department of the hospital Parity PARTURITION
下载PDF
Fear can be more harmful than the severe acute respiratory syndrome coronavirus 2 in controlling the corona virus disease 2019 epidemic 被引量:18
20
作者 Shi-Yan Ren Rong-Ding Gao Ye-Lin Chen 《World Journal of Clinical Cases》 SCIE 2020年第4期652-657,共6页
The current corona virus disease 2019 outbreak caused by severe acute respiratory syndrome coronavirus 2 started in Wuhan,China in December 2019 and has put the world on alert.To safeguard Chinese citizens and to stre... The current corona virus disease 2019 outbreak caused by severe acute respiratory syndrome coronavirus 2 started in Wuhan,China in December 2019 and has put the world on alert.To safeguard Chinese citizens and to strengthen global health security,China has made great efforts to control the epidemic.Many in the global community have joined China to limit the epidemic.However,discrimination and prejudice driven by fear or misinformation have been flowing globally,superseding evidence and jeopardizing the anti-severe acute respiratory syndrome coronavirus 2 efforts.We analyze this phenomenon and its underlying causes and suggest practical solutions. 展开更多
关键词 CORONAVIRUS Severe acute respiratory syndrome Severe acute respiratory syndrome coronavirus 2 Coronavirus disease 2019 OUTBREAK fear Discrimination PREJUDICE
下载PDF
上一页 1 2 172 下一页 到第
使用帮助 返回顶部