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The“Digital”Approach Impact Today:Modularity in Interior Architecture
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作者 Xinyi Tian 《Journal of World Architecture》 2024年第5期60-65,共6页
Understanding digital technology requires a shift in mindset that takes into account the broader implications of design,social dynamics,environmental factors,and cultural influences.Acknowledging the fact that technol... Understanding digital technology requires a shift in mindset that takes into account the broader implications of design,social dynamics,environmental factors,and cultural influences.Acknowledging the fact that technology is not confined to the virtual domain but rather has a tangible influence on our daily lives and the surrounding environment,the extensive integration and potential of digital technologies offer a distinctive prospect to fundamentally transform our shared comprehension of architecture.Digital technologies are revolutionizing design practices,manufacturing processes,and our engagement with and understanding of the built environment,by fostering the development of novel models that promote equity and inclusivity.The application of“digital technologies”can function as a methodology for examining and expressing the possible paths of emerging digital technologies.Extrapolate the expected impact of digital technologies on the design,development,and occupancy of the environment to achieve a more sustainable future in the long run.This paper will examine the potential connections and origins of digital technology concerning modularity,as well as the implications of modularity on forthcoming architectural developments in customization. 展开更多
关键词 modularity Modular architecture Interior architecture CUSTOMIZATION
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Dynamic evolutionary community detection algorithms based on the modularity matrix 被引量:2
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作者 陈建芮 洪志敏 +1 位作者 汪丽娜 乌兰 《Chinese Physics B》 SCIE EI CAS CSCD 2014年第11期686-691,共6页
Motivated by the relationship of the dynamic behaviors and network structure, in this paper, we present two efficient dynamic community detection algorithms. The phases of the nodes in the network can evolve according... Motivated by the relationship of the dynamic behaviors and network structure, in this paper, we present two efficient dynamic community detection algorithms. The phases of the nodes in the network can evolve according to our proposed differential equations. In each iteration, the phases of the nodes are controlled by several parameters. It is found that the phases of the nodes are ultimately clustered into several communities after a short period of evolution. They can be adopted to detect the communities successfully. The second differential equation can dynamically adjust several parameters, so it can obtain satisfactory detection results. Simulations on some test networks have verified the efficiency of the presented algorithms. 展开更多
关键词 community detection dynamic evolutionary modularity matrix SYNCHRONIZATION
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A mobile self-reconfigurable robot based on modularity 被引量:2
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作者 钟鸣 《High Technology Letters》 EI CAS 2009年第1期26-31,共6页
A novel mobile self-reconfigurable robot is presented. This robot consists of several independent units. Each unit is composed of modular components including ultrasonic sensor, camera, communication, computation, and... A novel mobile self-reconfigurable robot is presented. This robot consists of several independent units. Each unit is composed of modular components including ultrasonic sensor, camera, communication, computation, and mobility parts, and is capable of simple self-reconfiguring to enhance its mobility by expanding itself. Several units can not only link into a train or other shapes autonomously via camera and sensors to be a united whole robot for obstacle clearing, but also disjoin to be separate units under control after missions. To achieve small overall size, compact mechanical structures are adopted in modular components design, and a miniature advanced RISC machines (ARM) based embedded controller is developed for minimal power consumption and efficient global control. The docking experiment between two units has also been implemented. 展开更多
关键词 self-reconfigurable robot MOBILITY modularity DOCKING
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Link prediction in complex networks via modularity-based belief propagation 被引量:1
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作者 赖大荣 舒欣 Christine Nardini 《Chinese Physics B》 SCIE EI CAS CSCD 2017年第3期604-614,共11页
Link prediction aims at detecting missing, spurious or evolving links in a network, based on the topological information and/or nodes' attributes of the network. Under the assumption that the likelihood of the existe... Link prediction aims at detecting missing, spurious or evolving links in a network, based on the topological information and/or nodes' attributes of the network. Under the assumption that the likelihood of the existence of a link between two nodes can be captured by nodes' similarity, several methods have been proposed to compute similarity directly or indirectly, with information on node degree. However, correctly predicting links is also crucial in revealing the link formation mechanisms and thus in providing more accurate modeling for networks. We here propose a novel method to predict links by incorporating stochastic-block-model link generating mechanisms with node degree. The proposed method first recov- ers the underlying block structure of a network by modularity-based belief propagation, and based on the recovered block structural information it models the link likelihood between two nodes to match the degree sequence of the network. Experiments on a set of real-world networks and synthetic networks generated by stochastic block model show that our proposed method is effective in detecting missing, spurious or evolving links of networks that can be well modeled by a stochastic block model. This approach efficiently complements the toolbox for complex network analysis, offering a novel tool to model links in stochastic block model networks that are fundamental in the modeling of real world complex networks. 展开更多
关键词 link prediction complex network belief propagation modularity
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Research in Green Modularity Design Methodology 被引量:1
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作者 李方义 李剑峰 +3 位作者 段广洪 张洪潮 徐进永 马开岺 《Journal of Shanghai Jiaotong university(Science)》 EI 2005年第4期402-406,共5页
Green design and manufacturing is a proactive approach to minimize wastes during a product’s design stage, thus preventing future environmental impacts. Current modular design method mainly focuses on product functio... Green design and manufacturing is a proactive approach to minimize wastes during a product’s design stage, thus preventing future environmental impacts. Current modular design method mainly focuses on product functional and manufacturing issues. In this paper, a theoretical scheme of multi-objective modularity analysis for discrete electromechanical product design was proposed. Product physical architecture was represented by a fuzzy graph, where fuzzy relationships contain environmental objectives and influence module formulation. Finally the optimal product modules combining all objectives can be searched by clustering algorithm. 展开更多
关键词 green design modularity fuzzy graph analytic hierarchy process (AHP)
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Interpreting Nestedness and Modularity Structures in Affiliation Networks: An Application in Knowledge Networks Formed by Software Project Teams 被引量:1
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作者 Jorge Luiz dos Santos Renelson Ribeiro Sampaio 《Social Networking》 2021年第1期1-18,共18页
An understanding of the knowledge creation and diffusion process in the organizational context is extremely relevant. Because from this understanding, organizations can restructure processes, reorient teams and implem... An understanding of the knowledge creation and diffusion process in the organizational context is extremely relevant. Because from this understanding, organizations can restructure processes, reorient teams and implement methodologies to assist in the construction of an evolutionary process of knowledge creation and diffusion aimed at sustainable growth and innovation. The theory of complex social networks has been applied in several fields to help understand organizational cognitive processes. However, these approaches still insipiently consider the analysis of the nestedness and modularity of the studied networks. In this article, we presented an approach that sought to identify patterns of nestedness and modularity in networks of affiliation of people in projects in the organizational context. The study sought to identify these patterns in affiliation networks in a public organization providing information technology services in the period from 2006 to 2013. The detection of these patterns was performed using the NODF (Nestedness metric based on Overlap and Decreasing Fill) algorithm described by <a href="#ref1">[1]</a>. The nestedness and modularity metrics can influence patterns of knowledge creation and diffusion in formal and informal networks constituted for the execution of projects in organizations. This study showed that the network structures of the organization during the study period presented a high degree of nestedness, and it was possible to identify combined structures of nestedness and modularity. 展开更多
关键词 Social Network Analysis Affiliation Networks modularity NESTEDNESS
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Pseudotumor recurrence in a post-revision total hip arthroplasty with stem neck modularity: A case report 被引量:1
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作者 Bhumit R Desai Gonzalo E Sumarriva George F Chimento 《World Journal of Orthopedics》 2020年第2期116-122,共7页
BACKGROUND This unique presentation of hip swelling is only the seventh reported case of pseudotumor recurrence in a non-metal-on-metal total hip arthroplasty(THA)construct.The constellation of patient symptoms and la... BACKGROUND This unique presentation of hip swelling is only the seventh reported case of pseudotumor recurrence in a non-metal-on-metal total hip arthroplasty(THA)construct.The constellation of patient symptoms and laboratory findings contradict the expected elevated serum metal ion levels associated with the formation of pseudotumor.The presentation,lab trends,and imaging findings contribute to the growing base of knowledge surrounding the effects of corrosion in arthroplasty constructs with stem-neck modularity.CASE SUMMARY A 74-year-old man status post primary THA presented with left hip swelling and elevated serum metal ions five years after implantation of a modular stem-neck prosthesis.The swelling was diagnosed as pseudotumor based on laboratory trends and imaging findings and was treated with revision arthroplasty that completely resolved the initial hip swelling.The patient presented with recurrent hip swelling and recurrent pseudotumor findings on imaging in the same hip four months later.Non-operative management with ultrasound-guided hip aspiration resulted in symptom relief and resolution of the recurrent swelling.After one year of follow-up,the patient had no further recurrences of hip swelling.CONCLUSION This case of post-revision pseudotumor recurrence elucidates attributable patient,surgical,and implant factors with a discussion of diagnostics,management,and prognosis for patients with pseudotumor in non-metal-on-metal arthroplasty constructs. 展开更多
关键词 Revision arthroplasty PSEUDOTUMOR Stem-neck modularity Pseudotumor recurrence Metal-on-metal arthroplasty Modular stem Case report
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Modularity,module reintegration and industry landscape remaking
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作者 李晓华 《China Economist》 2010年第5期119-128,共10页
The turn-key solution originated by Media Tek Inc.(MTK) changed the degree of handset modularity and sparked therise of "knockoff handsets’’ This paper holds that modularity is not a product of independent evol... The turn-key solution originated by Media Tek Inc.(MTK) changed the degree of handset modularity and sparked therise of "knockoff handsets’’ This paper holds that modularity is not a product of independent evolution and that thechange in the degree of product modularity will lead to a change in the product’s organizational structure.Modulereintegration has reduced the industry’s knowledge barrier and made it possible for a large number of low-tech firms toenter the industry in China.As a result, it has altered the industry’s competitive landscape.Module reintegration can betaken as an important path for industrial upgrade, and the industry regulatory policies shall also be adjusted accordingto the changes in this industry’s characteristics. 展开更多
关键词 modularity MODULE REINTEGRATION value CHAIN INDUSTRY LANDSCAPE
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Modularity Techniques in High Performance Permanent Magnet Machines and Applications 被引量:2
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作者 Z.Q.Zhu Y.X.Li 《CES Transactions on Electrical Machines and Systems》 2018年第1期93-103,共11页
This paper reviews the modularity techniques in the stator manufacture of permanent magnet machines for different applications.Some basic concepts of modular machines are firstly introduced.Modular machines for severa... This paper reviews the modularity techniques in the stator manufacture of permanent magnet machines for different applications.Some basic concepts of modular machines are firstly introduced.Modular machines for several typical applications are then described in details,including domestic appliances,automobiles and electric vehicles,more electric aircrafts and civic applications,wind power generators,etc.Besides,the influence of manufacture tolerance gaps and flux barriers on the electromagnetic performance is discussed. 展开更多
关键词 Domestic appliance electric vehicle(EV) modular machine more electric aircraft permanent magnet wind power generator
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Modularity,reconfigurability,and autonomy for the future in spacecraft:A review 被引量:1
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作者 Zhibin ZHANG Xinhong LI +4 位作者 Yanyan LI Gangxuan HU Xun WANG Guohui ZHANG Haicheng TAO 《Chinese Journal of Aeronautics》 SCIE EI CAS CSCD 2023年第7期282-315,共34页
The shape of a spacecraft is transitioning from monolithic,manual,and static to modular,autonomous,and dynamic.Modular Reconfigurable Spacecrafts(MRSs)offer better solutions than traditional monolithic spacecrafts in ... The shape of a spacecraft is transitioning from monolithic,manual,and static to modular,autonomous,and dynamic.Modular Reconfigurable Spacecrafts(MRSs)offer better solutions than traditional monolithic spacecrafts in several aspects,and may become the next generation of spacecraft systems with efficient design,fast deployment,flexible application,and convenient management.This paper reviews the development and technology of MRS from three aspects:Modularity,reconfigurability,and autonomy.Despite the progress of research on MRS,there is still a lack of unified standards and little understanding of related concepts.Based on the understanding of basic concepts,the studies conducted on MRS are reviewed to identify technical requirements and solutions.Aiming at the future development trend of MRS,a novel modular selfreconfigurable spacecraft,referred to as MagicSat,is proposed.Furthermore,the MagicSat system composition,advantages,and application prospects are studied.The enabling technologies and major challenges of MRS are further analyzed in terms of modularization,integrated management,and self-reconfiguration technologies.Finally,the future development trend of MRS technology is predicted,and corresponding suggestions are provided. 展开更多
关键词 Autonomous Deformable Modular Reconfigurable Spacecraft(MRS) Modular Self-Reconfigurable Spacecraft(MSRS) On-Orbit Service(OOS) SELF-RECONFIGURATION
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Community detection on elite mathematicians’collaboration network
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作者 Yurui Huang Zimo Wang +1 位作者 Chaolin Tian Yifang Ma 《Journal of Data and Information Science》 CSCD 2024年第4期1-23,共23页
Purpose:This study focuses on understanding the collaboration relationships among mathematicians,particularly those esteemed as elites,to reveal the structures of their communities and evaluate their impact on the fie... Purpose:This study focuses on understanding the collaboration relationships among mathematicians,particularly those esteemed as elites,to reveal the structures of their communities and evaluate their impact on the field of mathematics.Design/methodology/approach:Two community detection algorithms,namely Greedy Modularity Maximization and Infomap,are utilized to examine collaboration patterns among mathematicians.We conduct a comparative analysis of mathematicians’centrality,emphasizing the influence of award-winning individuals in connecting network roles such as Betweenness,Closeness,and Harmonic centrality.Additionally,we investigate the distribution of elite mathematicians across communities and their relationships within different mathematical sub-fields.Findings:The study identifies the substantial influence exerted by award-winning mathematicians in connecting network roles.The elite distribution across the network is uneven,with a concentration within specific communities rather than being evenly dispersed.Secondly,the research identifies a positive correlation between distinct mathematical sub-fields and the communities,indicating collaborative tendencies among scientists engaged in related domains.Lastly,the study suggests that reduced research diversity within a community might lead to a higher concentration of elite scientists within that specific community.Research limitations:The study’s limitations include its narrow focus on mathematicians,which may limit the applicability of the findings to broader scientific fields.Issues with manually collected data affect the reliability of conclusions about collaborative networks.Practical implications:This study offers valuable insights into how elite mathematicians collaborate and how knowledge is disseminated within mathematical circles.Understanding these collaborative behaviors could aid in fostering better collaboration strategies among mathematicians and institutions,potentially enhancing scientific progress in mathematics.Originality/value:The study adds value to understanding collaborative dynamics within the realm of mathematics,offering a unique angle for further exploration and research. 展开更多
关键词 Greedy modularity maximization Infomap Collaboration network Community detection Mathematical awardees
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Leveraging React Components in Business Process Management (BPM) Applications
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作者 Ashok Reddy Annaram 《Journal of Computer and Communications》 2024年第4期86-94,共9页
As organizations increasingly embrace digital transformation, the integration of modern web technologies like React.js with Business Process Management (BPM) applications has become essential. React components offer f... As organizations increasingly embrace digital transformation, the integration of modern web technologies like React.js with Business Process Management (BPM) applications has become essential. React components offer flexibility, reusability, and scalability, making them ideal for enhancing user interfaces and driving user engagement within BPM environments. This article explores the benefits, challenges, and best practices of leveraging React components in BPM applications, along with real-world examples of successful implementations. 展开更多
关键词 React.js Digital Transformation User Interface (UI) Development Component-Based Architecture Declarative UI Development User Experience (UX) REUSABILITY modularity INTEGRATION CUSTOMIZATION Developer Productivity Legacy System Integration
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Risk Assessment of Deep-Water Horizontal X-Tree Installation 被引量:1
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作者 MENG Wen-bo FU Guang-ming +3 位作者 HUANG Yi LIU Shu-jie HUANG Liang GAOYong-hai 《China Ocean Engineering》 SCIE EI CSCD 2024年第2期210-220,共11页
Due to the high potential risk and many influencing factors of subsea horizontal X-tree installation,to guarantee the successful completion of sea trials of domestic subsea horizontal X-trees,this paper established a ... Due to the high potential risk and many influencing factors of subsea horizontal X-tree installation,to guarantee the successful completion of sea trials of domestic subsea horizontal X-trees,this paper established a modular risk evaluation model based on a fuzzy fault tree.First,through the analysis of the main process oftree down and combining the Offshore&Onshore Reliability Data(OREDA)failure statistics and the operation procedure and the data provided by the job,the fault tree model of risk analysis of the tree down installation was established.Then,by introducing the natural language of expert comprehensive evaluation and combining fuzzy principles,quantitative analysis was carried out,and the fuzzy number was used to calculate the failure probability of a basic event and the occurrence probability of a top event.Finally,through a sensitivity analysis of basic events,the basic events of top events significantly affected were determined,and risk control and prevention measures for the corresponding high-risk factors were proposed for subsea horizontal X-tree down installation. 展开更多
关键词 subsea horizontal X-tree risk assessment fuzzy fault tree modular risk evaluation model
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"Five steps four quadrants" modularized en bloc dissection technique for accessing hepatic hilum lymph nodes in laparoscopic pancreaticoduodenectomy 被引量:1
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作者 Xiao-Si Hu Yong Wang +5 位作者 Hong-Tao Pan Chao Zhu Shi-Lei Chen Hui-Chun Liu Qing Pang Hao Jin 《World Journal of Gastrointestinal Surgery》 SCIE 2024年第2期503-510,共8页
BACKGROUND Although en bloc dissection of hepatic hilum lymph nodes has many advantages in radical tumor treatment,the feasibility and safety of this approach for laparo-scopic pancreaticoduodenectomy(LPD)require furt... BACKGROUND Although en bloc dissection of hepatic hilum lymph nodes has many advantages in radical tumor treatment,the feasibility and safety of this approach for laparo-scopic pancreaticoduodenectomy(LPD)require further clinical evaluation and investigation.AIM To explore the application value of the"five steps four quadrants"modularized en bloc dissection technique for accessing hepatic hilum lymph nodes in LPD patients.METHODS A total of 52 patients who underwent LPD via the"five steps four quadrants"modularized en bloc dissection technique for hepatic hilum lymph nodes from April 2021 to July 2023 in our department were analyzed retrospectively.The patients'body mass index(BMI),preoperative laboratory indices,intraoperative variables and postoperative complications were recorded.The relationships between preoperative data and intraoperative lymph node dissection time and blood loss were also analyzed.RESULTS Among the 52 patients,36 were males and 16 were females,and the average age was 62.2±11.0 years.There were 26 patients with pancreatic head cancer,16 patients with periampullary cancer,and 10 patients with distal bile duct cancer.The BMI was 22.3±3.3 kg/m²,and the median total bilirubin(TBIL)concentration was 57.7(16.0-155.7)µmol/L.All patients successfully underwent the"five steps four quadrants"modularized en bloc dissection technique without lymph node clearance-related complications such as postoperative bleeding or lymphatic leakage.Correlation analysis revealed significant associations between preoperative BMI(r=0.3581,P=0.0091),TBIL level(r=0.2988,P=0.0341),prothrombin time(r=0.3018,P=0.0297)and lymph node dissection time.Moreover,dissection time was significantly correlated with intraoperative blood loss(r=0.7744,P<0.0001).Further stratified analysis demonstrated that patients with a preoperative BMI≥21.9 kg/m²and a TIBL concentration≥57.7μmol/L had significantly longer lymph node dissection times(both P<0.05).CONCLUSION The"five steps four quadrants"modularized en bloc dissection technique for accessing the hepatic hilum lymph node is safe and feasible for LPD.This technique is expected to improve the efficiency of hepatic hilum lymph node dissection and shorten the learning curve;thus,it is worthy of further clinical promotion and application. 展开更多
关键词 Five steps four quadrants Hepatic hilum lymph node Modularized en bloc clearance Laparoscopic pancreaticoduodenectomy
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Protein interaction networks:centrality,modularity,dynamics,and applications 被引量:2
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作者 Xiangmao MENG Wenkai LI +2 位作者 Xiaoqing PENG Yaohang LI Min LI 《Frontiers of Computer Science》 SCIE EI CSCD 2021年第6期1-17,共17页
In the post-genomic era,proteomics has achieved significant theoretical and practical advances with the development of high-throughput technologies.Especially the rapid accumulation of protein-protein interactions(PPI... In the post-genomic era,proteomics has achieved significant theoretical and practical advances with the development of high-throughput technologies.Especially the rapid accumulation of protein-protein interactions(PPIs)provides a foundation for constructing protein interaction networks(PINs),which can furnish a new perspective for understanding cellular organizations,processes,and functions at network level.In this paper,we present a comprehensive survey on three main characteristics of PINs:centrality,modularity,and dynamics.1)Different centrality measures,which are used to calculate the importance of proteins,are summarized based on the structural characteristics of PINs or on the basis of its integrated biological information;2)Different modularity definitions and various clustering algorithms for predicting protein complexes or identifying functional modules are introduced;3)The dynamics of proteins,PPIs and sub-networks are discussed,respectively.Finally,the main applications of PINs in the complex diseases are reviewed,and the challenges and future research directions are also discussed. 展开更多
关键词 protein interaction networks network centrality modularity DYNAMICS complex diseases
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Modularity-like objective function in annotated networks 被引量:1
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作者 Jia-Rong Xie Bing-Hong Wang 《Frontiers of physics》 SCIE CSCD 2017年第6期109-113,共5页
We ascertain the modularity-like objective function whose optimization is equivalent to the maximum likelihood in annotated networks. We demonstrate that the modularity-like objective function is a lin- ear combinatio... We ascertain the modularity-like objective function whose optimization is equivalent to the maximum likelihood in annotated networks. We demonstrate that the modularity-like objective function is a lin- ear combination of modularity and conditional entropy. In contrast with statistical inference methods, in our method, the influence of the metadata is adjustable; when its influence is strong enough, the metadata can be recovered. Conversely, when it is weak, the detection may correspond to another partition. Between the two, there is a transition. This paper provides a concept for expanding the scope of modularity methods. 展开更多
关键词 community structure annotated networks modularity objective function
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A Modularity Analysis Method for Forum Situation Prediction 被引量:1
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作者 QIAN Ailing QU Binbin +1 位作者 LU Yansheng HUANG Jin 《Wuhan University Journal of Natural Sciences》 CAS 2011年第2期148-154,共7页
A forum is a social network that consists of posters and the following comments made by netizens. Generally speaking, forum topics are evolving over time dynamically. In this paper, based on time series analysis and m... A forum is a social network that consists of posters and the following comments made by netizens. Generally speaking, forum topics are evolving over time dynamically. In this paper, based on time series analysis and matrix modularity analysis, a novel prediction method is proposed through investigating the correlating influence of three key measurements: relationship strength, pillars, and change frequency of a forum topic. The method demonstrates that there exist some macroscopic and potential laws for forum situation prediction. Extensive experiments over large many datasets show the efficiency and effectiveness of the algorithms. 展开更多
关键词 time series social network forum sentiment situation prediction modularity analysis
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Fixed-Time Sliding Mode Control With Varying Exponent Coefficient for Modular Reconfigurable Flight Arrays
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作者 Jianquan Yang Chunxi Yang +1 位作者 Xiufeng Zhang Jing Na 《IEEE/CAA Journal of Automatica Sinica》 SCIE EI CSCD 2024年第2期514-528,共15页
The modular system can change its physical structure by self-assembly and self-disassembly between modules to dynamically adapt to task and environmental requirements. Recognizing the adaptive capability of modular sy... The modular system can change its physical structure by self-assembly and self-disassembly between modules to dynamically adapt to task and environmental requirements. Recognizing the adaptive capability of modular systems, we introduce a modular reconfigurable flight array(MRFA) to pursue a multifunction aircraft fitting for diverse tasks and requirements,and investigate the attitude control and the control allocation problem by using the modular reconfigurable flight array as a platform. First, considering the variable and irregular topological configuration of the modular array, a center-of-mass-independent flight array dynamics model is proposed to allow control allocation under over-actuated situations. Secondly, in order to meet the stable, fast and accurate attitude tracking performance of the MRFA, a fixed-time convergent sliding mode controller with state-dependent variable exponent coefficients is proposed to ensure fast convergence rate both away from and near the system equilibrium point without encountering the singularity. It is shown that the controller also has fixed-time convergent characteristics even in the presence of external disturbances. Finally,simulation results are provided to demonstrate the effectiveness of the proposed modeling and control strategies. 展开更多
关键词 Control allocation dynamic model fixed-time stabilization modular reconfigurable flight array(MRFA) sliding mode
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Customized scaffolds for large bone defects using 3D‑printed modular blocks from 2D‑medical images
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作者 Anil AAcar Evangelos Daskalakis +4 位作者 Paulo Bartolo Andrew Weightman Glen Cooper Gordon Blunn Bahattin Koc 《Bio-Design and Manufacturing》 SCIE EI CAS CSCD 2024年第1期74-87,共14页
Additive manufacturing(AM)has revolutionized the design and manufacturing of patient-specific,three-dimensional(3D),complex porous structures known as scaffolds for tissue engineering applications.The use of advanced ... Additive manufacturing(AM)has revolutionized the design and manufacturing of patient-specific,three-dimensional(3D),complex porous structures known as scaffolds for tissue engineering applications.The use of advanced image acquisition techniques,image processing,and computer-aided design methods has enabled the precise design and additive manufacturing of anatomically correct and patient-specific implants and scaffolds.However,these sophisticated techniques can be timeconsuming,labor-intensive,and expensive.Moreover,the necessary imaging and manufacturing equipment may not be readily available when urgent treatment is needed for trauma patients.In this study,a novel design and AM methods are proposed for the development of modular and customizable scaffold blocks that can be adapted to fit the bone defect area of a patient.These modular scaffold blocks can be combined to quickly form any patient-specific scaffold directly from two-dimensional(2D)medical images when the surgeon lacks access to a 3D printer or cannot wait for lengthy 3D imaging,modeling,and 3D printing during surgery.The proposed method begins with developing a bone surface-modeling algorithm that reconstructs a model of the patient’s bone from 2D medical image measurements without the need for expensive 3D medical imaging or segmentation.This algorithm can generate both patient-specific and average bone models.Additionally,a biomimetic continuous path planning method is developed for the additive manufacturing of scaffolds,allowing porous scaffold blocks with the desired biomechanical properties to be manufactured directly from 2D data or images.The algorithms are implemented,and the designed scaffold blocks are 3D printed using an extrusion-based AM process.Guidelines and instructions are also provided to assist surgeons in assembling scaffold blocks for the self-repair of patient-specific large bone defects. 展开更多
关键词 Additive manufacturing Modular scaffolds Large bone defect Customized scaffold design Patient-specific scaffolds
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Rapid fabrication of modular 3D paper-basedmicrofluidic chips using projection-based 3D printing
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作者 Mingjun Xie Zexin Fu +5 位作者 Chunfei Lu Sufan Wu Lei Pan Yong He Yi Sun Ji Wang 《Bio-Design and Manufacturing》 SCIE EI CAS CSCD 2024年第5期611-623,共13页
Paper-based microchips have different advantages,such as better biocompatibility,simple production,and easy handling,making them promising candidates for clinical diagnosis and other fields.This study describes ametho... Paper-based microchips have different advantages,such as better biocompatibility,simple production,and easy handling,making them promising candidates for clinical diagnosis and other fields.This study describes amethod developed to fabricate modular three-dimensional(3D)paper-based microfluidic chips based on projection-based 3D printing(PBP)technology.A series of two-dimensional(2D)paper-based microfluidic modules was designed and fabricated.After evaluating the effect of exposure time on the accuracy of the flow channel,the resolution of this channel was experimentally analyzed.Furthermore,several 3D paper-based microfluidic chips were assembled based on the 2D ones using different methods,with good channel connectivity.Scaffold-based 2D and hydrogel-based 3D cell culture systems based on 3D paper-based microfluidic chips were verified to be feasible.Furthermore,by combining extrusion 3D bioprinting technology and the proposed 3D paper-based microfluidic chips,multiorgan microfluidic chips were established by directly printing 3D hydrogel structures on 3D paperbased microfluidic chips,confirming that the prepared modular 3D paper-based microfluidic chip is potentially applicable in various biomedical applications. 展开更多
关键词 Paper-based microfluidic chip Projection-based 3D printing(PBP) Modularization Cell culture
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